LOCUS       NM_181707                975 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens CHD1 helical C-terminal domain containing 1 (CHCT1),
            mRNA.
ACCESSION   NM_181707
VERSION     NM_181707.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Dai,Y., Nie,J., Luo,Z. and Nie,D.
  TITLE     Expression profile analysis of a new testis-specifically expressed
            gene C17ORF64 and its association with cell apoptosis in MCF-7
            cells
  JOURNAL   Mol Biol Rep 48 (2), 1521-1529 (2021)
   PUBMED   33566224
  REMARK    GeneRIF: Expression profile analysis of a new testis-specifically
            expressed gene C17ORF64 and its association with cell apoptosis in
            MCF-7 cells.
REFERENCE   2  (bases 1 to 975)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   3  (bases 1 to 975)
  AUTHORS   Mohanty,B., Helder,S., Silva,A.P., Mackay,J.P. and Ryan,D.P.
  TITLE     The Chromatin Remodelling Protein CHD1 Contains a Previously
            Unrecognised C-Terminal Helical Domain
  JOURNAL   J Mol Biol 428 (21), 4298-4314 (2016)
   PUBMED   27591891
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC037475.9, DB448877.1, BC036356.1 and CD742737.1.
            
            On Nov 23, 2018 this sequence version replaced NM_181707.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036356.1, BI827561.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000269127.5/ ENSP00000269127.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AC037475.9         41185-41199         c
            16-20               DB448877.1         1-5
            21-970              BC036356.1         1-950
            971-975             CD742737.1         18-22               c
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q23.2"
     gene            1..975
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /note="CHD1 helical C-terminal domain containing 1"
                     /db_xref="GeneID:124773"
                     /db_xref="HGNC:HGNC:26990"
     exon            1..155
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..815
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /note="uncharacterized protein C17orf64"
                     /codon_start=1
                     /product="CHD1 helical C-terminal domain containing
                     protein 1"
                     /protein_id="NP_859058.2"
                     /db_xref="CCDS:CCDS32698.2"
                     /db_xref="GeneID:124773"
                     /db_xref="HGNC:HGNC:26990"
                     /translation="MEASDGQGGEGDKPLEQVTNVSCLETSSSASPARDSLMRHAKGL
                     DQDTFKTCKEYLRPLKKFLRKLHLPRDLPQKKKLKYMKQSLVVLGDHINTFLQHYCQA
                     WEIKHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQPAKFLVTFCASDAPERSLLADR
                     EDSLPKLCHAWGLHSNISGMKERLSNMQTPGQGSPLPGQPRSQDHVKKDSLRELSQKP
                     KLKRKRIKEAPETPETEP"
     exon            156..257
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /inference="alignment:Splign:2.1.0"
     exon            258..433
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /inference="alignment:Splign:2.1.0"
     exon            434..533
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /inference="alignment:Splign:2.1.0"
     exon            534..729
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /inference="alignment:Splign:2.1.0"
     exon            730..975
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /inference="alignment:Splign:2.1.0"
     regulatory      946..951
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /note="hexamer: AATAAA"
     polyA_site      975
                     /gene="CHCT1"
                     /gene_synonym="C17orf64"
                     /note="major polyA site"
ORIGIN      
        1 aaaccgccca ctccctgaga cggctaggtc acagaagcag tgggtcagaa gccagagggg
       61 acgtggggag tgccaccctg gagcctaccg gcacacctgc tgagatggag gcctcagatg
      121 ggcaaggggg tgaaggggac aagccactag agcaggtgac aaatgtgtca tgcctggaga
      181 caagctccag cgccagccct gctagagact cgctcatgcg ccatgccaag ggcctggatc
      241 aggacacctt caaaacttgt aaagaatacc taagaccgct gaagaagttc ctgcgaaagt
      301 tgcacctgcc cagggacctt ccccagaaga agaagctgaa gtacatgaag cagagccttg
      361 tggtcctagg ggaccacatc aacacctttc tgcagcatta ctgccaagcc tgggaaatca
      421 aacactggag aaagatgctc tggcggttca tctccctctt ctcggagctg gaagcaaagc
      481 agcttcgccg actttacaag tacaccaaga gcagccagcc ggccaagttc ctggtgacat
      541 tctgcgcctc ggatgcgccg gagaggtcct tgctggccga ccgggaagac agtctgccca
      601 agctctgcca tgcatggggg ctgcacagca acatcagcgg catgaaggag cggctgtcca
      661 acatgcagac cccaggtcaa gggagccccc tgcctgggca gccaagatcc caggaccatg
      721 tcaagaaaga ttctttaagg gagctttctc aaaaaccaaa actcaagagg aagaggataa
      781 aggaagcccc agaaactcca gagactgaac cgtaagaaga ccaactggga caaagggccc
      841 gcttgtcctg gctctcagag cacggggaat ggagaccaaa aagggaaaag aattgtcctt
      901 atcaaaaaga ttctcaggtc ttaattagga ataaatgagg tgggaaataa acattcttat
      961 gacagttcta cctta
//
