LOCUS       NM_001079530            1643 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens cryptic, EGF-CFC family member 1B (CFC1B), mRNA.
ACCESSION   NM_001079530 XM_928615 XM_932990
VERSION     NM_001079530.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC013269.10, BQ777283.1, BU784123.1 and BM716751.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001079530.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2154405,
                              SAMEA2157511 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000281882.8/ ENSP00000281882.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AC013269.10        59246-59275
            31-487              BQ777283.1         1-457
            488-608             BU784123.1         471-591
            609-1032            BM716751.1         9-432
            1033-1643           AC013269.10        66017-66627
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q21.1"
     gene            1..1643
                     /gene="CFC1B"
                     /note="cryptic, EGF-CFC family member 1B"
                     /db_xref="GeneID:653275"
                     /db_xref="HGNC:HGNC:33983"
     exon            1..286
                     /gene="CFC1B"
                     /inference="alignment:Splign:2.1.0"
     CDS             264..935
                     /gene="CFC1B"
                     /note="cryptic family protein 1B; cripto, FRL-1, cryptic
                     family 1B"
                     /codon_start=1
                     /product="cryptic family protein 1B precursor"
                     /protein_id="NP_001072998.1"
                     /db_xref="CCDS:CCDS33286.1"
                     /db_xref="GeneID:653275"
                     /db_xref="HGNC:HGNC:33983"
                     /translation="MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQ
                     KHRQSPLNWTSSHFGEVTGSAEGWGPEEPLPYSWAFGEGASARPRCCRNGGTCVLGSF
                     CVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPK
                     DFLASHAHGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPG
                     LGHRL"
     exon            287..336
                     /gene="CFC1B"
                     /inference="alignment:Splign:2.1.0"
     exon            337..510
                     /gene="CFC1B"
                     /inference="alignment:Splign:2.1.0"
     exon            511..625
                     /gene="CFC1B"
                     /inference="alignment:Splign:2.1.0"
     exon            626..735
                     /gene="CFC1B"
                     /inference="alignment:Splign:2.1.0"
     exon            736..1643
                     /gene="CFC1B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1010..1015
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFC1B"
                     /note="hexamer: AATAAA"
     polyA_site      1033
                     /gene="CFC1B"
                     /note="major polyA site"
     regulatory      1626..1631
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFC1B"
                     /note="hexamer: AATAAA"
     polyA_site      1642
                     /gene="CFC1B"
ORIGIN      
        1 atagagggaa ttgttcttca ggctcggagg ggcctgcctg tcactgcgcc cccgacccta
       61 gctcagggac tgcagaactc aagataccat cccgtttctc ctggctgagg aagggaaggg
      121 aacatccaca tcttctgtac tcgtccattc tgtgtccccg gggcctggag taaagacacc
      181 ttcaaatgca gagactcttc agattcagct ttcctggaaa ctgatcttca atgcactaag
      241 agaaggagac tctcaaacca aaaatgacct ggaggcacca tgtcaggctt ctgtttacgg
      301 tcagtttggc attacagatc atcaatttgg gaaacagcta tcaaagagag aaacataacg
      361 gcggtagaga ggaagtcacc aaggttgcca ctcagaagca ccgacagtca ccgctcaact
      421 ggacctccag tcatttcgga gaggtgactg ggagcgccga gggctggggg ccggaggagc
      481 cgctcccata ctcctgggct ttcggagagg gtgcgtccgc gcggccgcgc tgctgcagga
      541 acggcggtac ctgcgtgctg ggcagcttct gcgtgtgccc ggcccacttc accggccgct
      601 actgcgagca tgaccagagg cgcagtgaat gcggcgccct ggagcacgga gcctggaccc
      661 tccgcgcctg ccacctctgc aggtgcatct tcggggccct gcactgcctc cccctccaga
      721 cgcctgaccg ctgtgacccg aaagacttcc tggcctccca cgctcacggg ccgagcgccg
      781 ggggcgcgcc cagcctgcta ctcttgctgc cctgcgcact cctgcaccgc ctcctgcgcc
      841 cggatgcgcc cgcgcaccct cggtccctgg tcccttccgt cctccagcgg gagcggcgcc
      901 cctgcggaag gccgggactt gggcatcgcc tttaattttc tatgttgtaa ataatagatg
      961 tgtttagttt accgtaagct gaagcactgg gtgaatattt ttattgggta ataaatattt
     1021 tcatgaaagc gcctttggct ccagatcctt gggagaggga cacgtgtgtc cccagcacca
     1081 ctgtgaccgg taggtagaga cagcagaaca acagcgagaa ggagccaaag ctggagccag
     1141 aaagcctggc accgccacct tcccctgaca gttagcacct tcctttcaca acatctccct
     1201 taagggggaa gcgtctgctg tggaacccac cgcaaggcaa cgcaggcaga gttcagcctg
     1261 aagagcgcca ggccagcctc ctctgtcttc cgagcaccgc ttctcaggtc gcttcccaat
     1321 ctgaggaggc tgtcgtgtcc acaaccagtc cagggggatg tgcgccacta gctgaggacg
     1381 ccaggcccgg cgacaccaca aaggcttggc catgcggaat gtgccctcaa gagcacacac
     1441 ttcgggtaga aggcacttgc attgagctct tcagcttttt aaatccactg tagttcatga
     1501 gcctgtgtga cacaattact tttacatttt atattgtcaa ttagtttatt ggcattttca
     1561 atcttttcaa ctattggcta tgaaaatatg aatttaacgt aacattcaaa tgagtattaa
     1621 agaaaaataa agtagaactt cat
//
