LOCUS       NM_001193282            2173 bp    mRNA    linear   PRI 10-FEB-2025
DEFINITION  Homo sapiens cilia and flagella associated protein 99 (CFAP99),
            mRNA.
ACCESSION   NM_001193282 XM_001714276 XM_001716036 XM_938047 XR_041317
            XR_041318 XR_041319
VERSION     NM_001193282.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645924.13 and KF459867.1.
            
            On Aug 13, 2020 this sequence version replaced NM_001193282.3.
            
            Sequence Note: The RefSeq transcript was derived from the reference
            genome assembly because insufficient transcript evidence was
            available to represent the locus. The genomic coordinates were
            determined from transcript and protein alignments, including Macaca
            EB521408.1, rat FM031983.1, Ciona XP_002119250.1 and chicken
            XP_420831.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1968540
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000635017.2/ ENSP00000488922.2
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               AL645924.13        97598-97736         c
            140-267             AL645924.13        90105-90232         c
            268-412             AL645924.13        79673-79817         c
            413-507             AL645924.13        78527-78621         c
            508-620             AL645924.13        73449-73561         c
            621-798             AL645924.13        71383-71560         c
            799-879             AL645924.13        66941-67021         c
            880-951             KF459867.1         153-224             c
            952-1023            AL645924.13        65673-65744         c
            1024-1112           AL645924.13        65339-65427         c
            1113-1317           AL645924.13        64345-64549         c
            1318-1459           AL645924.13        57827-57968         c
            1460-1611           AL645924.13        57433-57584         c
            1612-1817           AL645924.13        56449-56654         c
            1818-1980           AL645924.13        54086-54248         c
            1981-2173           AL645924.13        53689-53881         c
FEATURES             Location/Qualifiers
     source          1..2173
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p16.3"
     gene            1..2173
                     /gene="CFAP99"
                     /note="cilia and flagella associated protein 99"
                     /db_xref="GeneID:402160"
                     /db_xref="HGNC:HGNC:51180"
     exon            1..139
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            140..267
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..2097
                     /gene="CFAP99"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 99"
                     /protein_id="NP_001180211.2"
                     /db_xref="GeneID:402160"
                     /db_xref="HGNC:HGNC:51180"
                     /translation="MAYYGKCIETVIEQLDKFTPKRDNPEQFLEAAATSLQALSPQKQ
                     SFVLEVLSGCLEYRKLLTVVVDAFYVEDGRLCLRVDHSRFEVICYLATFLLEELGFQL
                     FCNIIKSQPVDKMCKFLRFFFNPLHLCSWIKDEWSLIYEPAHVKENWIDPLMRWQPEV
                     QELINHLEGVSASQSSPLKTKAKVTEPKEFNLTAPRPRTIPAPEPVPVVAKPRPVPQS
                     TYQPPKEQQQLETVKRYNRRKAEELLLRANIEELRCAMPRSCRERVQGSKQQLRLQFP
                     PRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQELQRVDKLVDGAGDFSEFF
                     EWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLM
                     LQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRA
                     QAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLK
                     ENQRRKEEEKRDQIIQGKHTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPA
                     APSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRAQLEAQHWLELERSRE
                     RRLQALQQGGSGPGPARRLEAA"
     exon            268..412
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            413..507
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            508..620
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            621..798
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            799..879
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            880..951
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1023
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1112
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1113..1317
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1459
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1611
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1817
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1980
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2173
                     /gene="CFAP99"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2153..2158
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP99"
                     /note="hexamer: AATAAA"
     polyA_site      2173
                     /gene="CFAP99"
                     /note="major polyA site"
ORIGIN      
        1 gccaaacagc cgcggcgtcc tgcctaccgg gagctgacgg acgacgactg ccaacacctt
       61 agccccagct ggcccaggaa actgctgcgg tggcaggtgg cggcggcagg agggctcggc
      121 tgccccgagc gcccgccagg cttctgccct aagaagatgg cctactatgg aaaatgcatt
      181 gaaactgtga tcgagcaact cgacaaattt acacccaaga gggacaaccc tgagcagttc
      241 ctggaggctg cggccacctc cctgcaggct ctgagccccc agaagcagag ctttgttttg
      301 gaggttctgt ctgggtgcct cgagtaccgg aagctgctga ccgtcgtggt ggatgccttc
      361 tacgtggagg atggccgact ctgcctgcgg gttgaccaca gccgcttcga ggtgatctgc
      421 tacctagcca cattcctgct ggaggaactc ggcttccagc tattctgtaa catcatcaag
      481 tcccagcccg tggataagat gtgcaagttc ctcaggttct tcttcaaccc cctgcacctg
      541 tgctcatgga tcaaggatga gtggagcctc atctacgagc cagcccacgt gaaggagaac
      601 tggatcgacc ccctgatgag atggcagcca gaggtccagg agctgatcaa ccacctggag
      661 ggcgtgtctg ccagtcaatc ctctccttta aagaccaagg ccaaggtcac agagcccaag
      721 gaattcaacc tgactgcccc caggccccgc accattccag cgcccgaacc agtcccggtc
      781 gtggccaagc cgagacccgt cccccagagc acctaccagc cacccaagga gcagcagcag
      841 ctggagacag tcaagaggta caaccgccga aaggccgagg agctgctgct gagggcaaac
      901 atcgaggaac tgcgctgcgc catgcccagg tcctgcaggg agcgagtgca gggctccaag
      961 cagcagctgc ggcttcagtt cccaccccga atccgaaaga ctccgaagct gaccttctat
     1021 aggcctgaca acatcctggt caagctgaac accacagcca tcctgcgaga aggggccttg
     1081 taccagcggc aggtggagca ggagctgcag agggttgata agctcgtgga tggggctggg
     1141 gacttctctg agttcttcga gtggcagaag aagatgcagg cgaaggaccg ggaggagcag
     1201 ctggctgcaa gcgagtgccg gcggttgcaa gggaagctta gccatgagga ggccgtccta
     1261 gcccggcaga gcctcatgca ggagaacaag cagagggtgg agcagcagaa ggagcagatg
     1321 gccaagctga tgctgcagcg tgcagagaga cggctccggg aggacaggtc caggaaggag
     1381 ctggtggagc aggtgataga ggggcagaag aacgccaagg cggcccagac gaagctcgcg
     1441 aagggccgac agcagacagt tcaggaggcg atcgaggaga gcagggggct gctgcagcgc
     1501 agggcgcagg cagcccagga ggagcagcgg cgccgttgtg aactcatctc ccagctgcgc
     1561 gcactcgaga cacagcccac gcgcaagggc aagctcgtgg acctgaccca gatccccggc
     1621 tacggcctgg aaggagagat gtccatagtg gagctgcgag agcggctggc cctgctcaaa
     1681 gagaatcagc ggcgcaagga ggaagaaaag cgggatcaaa tcattcaggg caagcacacc
     1741 aagagccagg aactgcagaa catggtggag cagatctcgc tgtgccgtgc agccatgggg
     1801 agatccgcag ccttgaggtg ggaggaaaag aaggcccttg cggcggcccc ggcggcgccc
     1861 tcgcaggacg agcgcgtgca gcagctgcgg cgcaggatct cggagagggc ggccgagcgc
     1921 agcaggcagg cggccttgct gcacgtgtcg gcgccgcgga ccgcgcgccc caagccccgg
     1981 gcgcagctag aggcgcagca ctggctggag ctggagcgga gccgcgagcg caggctgcag
     2041 gcgctgcagc agggaggctc aggacccggg cccgcgcgcc gcctggaggc cgcctgagcc
     2101 gggccgagcg cgccccaccc gcttgcgggc caccccctac acccgccgcc ccaataaaga
     2161 gtgcggcccg cgg
//
