LOCUS       NM_001136483            3761 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens CFAP97 domain containing 1 (CFAP97D1), transcript
            variant 1, mRNA.
ACCESSION   NM_001136483 XM_001722064 XM_208990 XM_937761
VERSION     NM_001136483.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3761)
  AUTHORS   Oura,S., Kazi,S., Savolainen,A., Nozawa,K., Castaneda,J., Yu,Z.,
            Miyata,H., Matzuk,R.M., Hansen,J.N., Wachten,D., Matzuk,M.M. and
            Prunskaite-Hyyrylainen,R.
  TITLE     Cfap97d1 is important for flagellar axoneme maintenance and male
            mouse fertility
  JOURNAL   PLoS Genet 16 (8), e1008954 (2020)
   PUBMED   32785227
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3761)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC070324.1 and AC003098.2.
            
            On May 17, 2019 this sequence version replaced NM_001136483.2.
            
            Transcript Variant: This variant (1) encodes the predominant
            isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK125817.1, BC070324.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000449302.8/ ENSP00000415662.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-968               BC070324.1         1-968
            969-3761            AC003098.2         35338-38130
FEATURES             Location/Qualifiers
     source          1..3761
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.31"
     gene            1..3761
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /note="CFAP97 domain containing 1"
                     /db_xref="GeneID:284067"
                     /db_xref="HGNC:HGNC:37241"
                     /db_xref="MIM:619866"
     exon            1..152
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..523
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C17orf105; CFAP97
                     domain-containing protein 1; sperm axonemal maintenance
                     protein CFAP97D1"
                     /codon_start=1
                     /product="sperm axonemal maintenance protein CFAP97D1
                     isoform 1"
                     /protein_id="NP_001129955.1"
                     /db_xref="CCDS:CCDS45695.1"
                     /db_xref="GeneID:284067"
                     /db_xref="HGNC:HGNC:37241"
                     /db_xref="MIM:619866"
                     /translation="MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKP
                     TVDTKPPVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNEYF
                     SKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRRYIRNTTRYLL
                     SQNE"
     exon            153..223
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /inference="alignment:Splign:2.1.0"
     exon            224..342
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /inference="alignment:Splign:2.1.0"
     exon            343..466
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /inference="alignment:Splign:2.1.0"
     exon            467..523
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /inference="alignment:Splign:2.1.0"
     exon            524..3761
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /inference="alignment:Splign:2.1.0"
     regulatory      629..634
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /note="hexamer: AATAAA"
     polyA_site      649
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /note="major polyA site"
     regulatory      955..960
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
                     /note="hexamer: AATACA"
     polyA_site      993
                     /gene="CFAP97D1"
                     /gene_synonym="C17orf105"
ORIGIN      
        1 atttctgaag tgagactagg aagagaagat gaacaattcc ctggattatc tggcctaccc
       61 tgttatcgtc tctaatcaca ggcaaagcac aaccttcaga aagaaactgg actttggcca
      121 ctacgtatct cacaagaata gaatacaaat agcgaagcct actgttgata ccaaacctcc
      181 agtggcgcac acaaatcaca ttttaaaatt gagcaaacta cagggtgaac aaaagaaaat
      241 caacaaaatc gagtatgaaa acaagcaact gtgtcagaaa atcgcaaatg cccatcgcgg
      301 ccctgccaag gtggattgct ggaatgaata tttttccaag agcttaaaca gagaaacaag
      361 gaaccgcgag ctagtgagaa tcaccatgga aaaccagggc attctgaaga ggcttgttga
      421 tcgcaaaccc cactatgacc gcagggcatc tgagatagac tggcagaatt caaggcgcta
      481 tatcagaaat accacgagat atcttctctc ccaaaatgaa taggttactc accatggaaa
      541 agatacaaga gaaggcccta ggatttcttg gctgctcagg atctcaagac actcccgact
      601 ggctgaatgc tccatcttca gatgcttcaa taaagcttgg aacataaaat gcgtaagtta
      661 catttagggg acccaaaggc tttatgttct cattccaaaa tggggcaggc agaaggaaag
      721 atgcaatgag catttttatt tggggctatg aaaagaagtt ttaacgagag agagagagag
      781 aaatctgaga gaactcttta aaacatacac catcatcacc atcccgtgga agaagaaaag
      841 ctggggtgag atcatccagc cacaagtaca gcactgtcaa aatggaaaac gaaatcacat
      901 gacaacatca aggttcagaa aacacaagga acaaatgcca ttagttcctc tgtgaataca
      961 cacgatcgga aaagaatgcc tcattgaagt ttccatggac tctgttcatt tatagggagc
     1021 agcagcagtg aaaatgtctc aaaacatacg gtgagacaat gttgcaggcc tgctatgatt
     1081 ggtcatgcta gttttcagcc caactatatt agtcagcatt tgccaaagag acagactcaa
     1141 taggagagag agagagagag agagagtgag agagatagat agagagtgag agagagagag
     1201 aaagagagag agagaggaga ggatttattt ggggaattgg ctcacaagat catggaagct
     1261 aaagaagtcc caccacaggc catctgcaag ctggagaccc tggtggagca gggcagacaa
     1321 cccccaaagt ggggcttagc ctgcgagtgt tcttggcttc acccaggaaa gaatttaagg
     1381 gtgagccagt ggtagggtag aagaagacag ttttattgaa gcagcagtgt tacagctcca
     1441 tgactgctcc tgcagtacag ggctacccca aaggcagaga gttttgcagt catagttata
     1501 cgtactttta attacatgta gattaagggg cggtttgtgc agaaattcta gggaaggagt
     1561 agtaattttt tttttttttt ttgagatgaa atctcactct gtcgcccagg ctggagtgca
     1621 gatggcgcga tctcagctca ctgcaacctc cgcctcctgg gttcaagcga ttctcctgcc
     1681 tcagcctccc aagtagctga gactacaggc actcgccacc acgcccagct aatttttgta
     1741 tttttagtag agacgaggtt tcaccatctt ggccaggctg gtcttgaact cctgacctcg
     1801 tgatccgccc gcctcggcct ctcaaagtgc tgggattaca ggcgtgagcc accatgtccg
     1861 gcctatagga aagggtagta atttttgggt ccttgggtca ttgccctgga aaggggtggt
     1921 aactcctagg tgttgctacg gtaatggtaa actgacatgg cacactagtg ggagtgtctt
     1981 atggaaagct gcttccaccc ctttcctgtt ttagctagtc ctcaattgga tcctgtgtcc
     2041 aagccccgcc tctggagtca aggcctgcct cccacctcac tgggatgctg gtagcatggc
     2101 ttggtccaag cccaaaaacc tcagaaccaa gaagaaggtg gtgtaactct cagttcgagg
     2161 ccaaaggctg agaacccact aggggggaca agggtgctgg tgtgagtctt ggagtacaaa
     2221 ggccaaggag cctagagttg ttgtcccagg acaggagagg aagagtgtat tccagttcca
     2281 gcagatagat tgacatattc gcctcttgtc tgtttttgtt ctttctgaat ccacagcaag
     2341 ttggatgatg cctctccaca ttgagagtgg atcttcccac atagttcact cagacttaca
     2401 tgctaatctc ccctggaaac actcacagac acacccaaaa ataatgcttt accaggtttc
     2461 tattcagtca agttggcacc ttaaattaac catcgcactg actttttaaa ctttctattt
     2521 tgaaataatg aaaattcaca ggtagttgca cataaaggaa cagggaggcc tcctgcaccc
     2581 tttacccagt ctccaccaat gttagcatct tgcgtaactg gagtacaata tcaaaaccag
     2641 gaaactgaca ttggcatgat gcatggaacc tatgcaggtt tcatcagtta tacatgcact
     2701 catttttgta catatatgta tagctctatg cggtttttgc cacatgtata gctttgtgta
     2761 accacattcg agatacttaa aaccactatt atcaaaagac actcttattg ccaccctttt
     2821 agccacagtc acctcagacc ctcaagccta actcttggca atcacaatct gttttccacc
     2881 tctctgttag ttcatggtat tacgtaaatg gcgtcatgca atgtatgttc atccttttga
     2941 gattggcttt tttcactcag gataatttcc ttgatgttca tccaagttgt gtgtgccttt
     3001 ttattgctga gtagtattcc atggtatgga catgctacaa tatatttaac catacatcca
     3061 tcaaaggaca ttggggtagt ttctagtttt tcaaacatta ttattattat tattattatt
     3121 attttgagat ggagtctcat tctgttgccc aggctggagt gcagtggcac gatcttggct
     3181 cactgcaacc tccacctctg gggttcaagc gattctcctg cctcagcctc ctgagtagct
     3241 gggattacaa gcatgcatca ccaggcccgg ctaattttta tatttttagt agagacaggg
     3301 tttcaccatg ttgacccggc tggtctcaaa ttcctgacct caggtgatcc acctgcctcg
     3361 gcctcccaaa gtgctgggat tacagacatg agccaccaca cctggcctga ttttttaaat
     3421 agcaaatttt gaaagttatt tacatattat aggaataagt cctttgcctg ctatgcgcct
     3481 tgcatgtatt tttctcccag tctataattt gtcttttcat cctcagggtc tttgacagag
     3541 taaaatattt ttatttggat gacatccaat atatcaatga tgaaactgtt ctatatcttg
     3601 actctatcaa tgtcaatatc cttgttgtga tactgtacca tatagttttg cactatgcta
     3661 ccactggggg aatctggtaa ggagtttaca ggatctctct gtattatttc ctacatgcat
     3721 gtgaatatac aattatctca aaataaaaag cttaaaaaaa a
//
