LOCUS       NM_001200049            8263 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens cilia and flagella associated protein 46 (CFAP46),
            mRNA.
ACCESSION   NM_001200049 XM_003118625 XM_003119478 XM_003120662
VERSION     NM_001200049.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8263)
  AUTHORS   Ayadi,W., Allaya,N., Frikha,H., Trigui,E., Khabir,A., Ghorbel,A.,
            Daoud,J., Frikha,M., Gargouri,A. and Mokdad-Gargouri,R.
  TITLE     Identification of a novel methylated gene in nasopharyngeal
            carcinoma: TTC40
  JOURNAL   Biomed Res Int 2014, 691742 (2014)
   PUBMED   25101295
  REMARK    GeneRIF: Hypermethylation of 5'-TTC40 gene might play a role in
            nasopharyngeal carcinoma development; nevertheless, other studies
            are needed.
REFERENCE   2  (bases 1 to 8263)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX376477.2, EL734348.1, AL691429.17, DV080197.1, DV080198.1,
            DV080663.1, CN285826.1, DV080697.1, DN930461.1, DY654537.1,
            DV080629.1, AL392043.21, BM726635.1, DV080489.1, DV080461.1 and
            BC034223.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001200049.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The exon combination of this RefSeq is
            predicted based on a combination of partial transcript alignments,
            RNA-seq alignments from Illumina's BodyMap 2.0 project, and
            homologous transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000368586.10/ ENSP00000357575.4
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-487               BX376477.2         16-502
            488-738             EL734348.1         402-652
            739-810             BX376477.2         754-825
            811-811             AL691429.17        53482-53482         c
            812-850             BX376477.2         827-865
            851-923             AL691429.17        51272-51344         c
            924-983             BX376477.2         938-997
            984-1052            AL691429.17        46196-46264         c
            1053-1151           AL691429.17        43059-43157         c
            1152-1325           AL691429.17        41204-41377         c
            1326-1627           DV080197.1         35-336
            1628-1666           DV080198.1         1-39                c
            1667-2092           DV080663.1         27-452
            2093-2198           AL691429.17        33048-33153         c
            2199-2299           CN285826.1         35-135
            2300-2357           AL691429.17        29599-29656         c
            2358-2660           CN285826.1         194-496
            2661-3042           DV080697.1         54-435
            3043-3084           AL691429.17        16084-16125         c
            3085-3752           DN930461.1         11-678              c
            3753-3970           DY654537.1         228-445
            3971-4147           DV080629.1         267-443
            4148-4188           AL392043.21        200546-200586       c
            4189-4724           BM726635.1         1-536
            4725-4984           DV080489.1         141-400
            4985-5116           AL392043.21        183398-183529       c
            5117-5722           DV080461.1         17-622
            5723-7076           BC034223.1         206-1559
            7077-7077           AL392043.21        156039-156039       c
            7078-7703           BC034223.1         1561-2186
            7704-7704           AL392043.21        133010-133010       c
            7705-7750           BC034223.1         2188-2233
            7751-7751           AL392043.21        131459-131459       c
            7752-8263           BC034223.1         2235-2746
FEATURES             Location/Qualifiers
     source          1..8263
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.3"
     gene            1..8263
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /note="cilia and flagella associated protein 46"
                     /db_xref="GeneID:54777"
                     /db_xref="HGNC:HGNC:25247"
                     /db_xref="MIM:618543"
     exon            1..135
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..8234
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /note="TPR repeat-containing protein C10orf93;
                     tetratricopeptide repeat domain 40; tetratricopeptide
                     repeat protein 40"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 46"
                     /protein_id="NP_001186978.2"
                     /db_xref="CCDS:CCDS58101.1"
                     /db_xref="GeneID:54777"
                     /db_xref="HGNC:HGNC:25247"
                     /db_xref="MIM:618543"
                     /translation="MDLVITQELARAESQQDAASLKKAYELIKSANLGKSEFDPSESF
                     SPDLFVLCAEQALKMRQPEVSEDCIQMYFKVKAPITQFLGRAHLCRAQMCAPKSAENL
                     EEFENCVTEYMKAINFAKGEPRYYFLVYNASVLYWQMVRPFLKPGYRHHLIPSLSQII
                     NVLSQTEEEDKEWRAELMLELLECYLQAGRKEEAARFCSTAAPFIKSHVPQKYRQIFS
                     VMVRHELMDELQLKEEKKNSISLSVTFYINMLKAKAEQNDLPGDISVILRKAYRHLGH
                     YNHQRFPSISEEKMLLLFELARFSLTLKCMEISSACLSDLKKMESKDPGKLIEMECLE
                     CESEALRLESKMKVYNRAAVEAQLDIIQRLDVALQRAVRLGDPRVIHVVCATQWNTCL
                     PLLQHNLRHHLRKPLAGVADVLEKLDSLMTLLRCQVHMEMAQIEEDEDRLEPATEHLR
                     KAARLDSLGLYRDRIQMASTRLRLCTTLYQAPERAEDKAIMAVEQAKKATPKDSVRKK
                     RALLVNAGLALAPDAFQIVLDSENEAKVSTGKNRGRFTYLCAKAWHHTVSVDKAAGHL
                     RRLGNENDKERIQIWAELAKVARKQGVWDVCRTASRFCLLYDNVKVKKLRLRRGKKKR
                     GRDGSVQDTWSQPEVVLQRQVCPDLLRKFAEVGFIHAEATVHLLRSEGVELNDRAIPP
                     EDLSQHPAGYVPEPPEVNAEWITYRTWIESLSRCAMNNWLRSAEIGQEIQEAWIVQNA
                     VVYVLNHNHHLILAGRQKELVDALYHLLSIVKATGHSGDPVMLVTLCNTLARGLIISW
                     IPVQAAEKSRKFMRPNAFHSPLDAGATSEIKTAVEVCEFALNLTNGSAPEETVPTGTR
                     QQLIATWVKAKQLLQQQIGPRLGTEEQGTNEDVSSVTRVLVALEMYSCNGLGLMDFTV
                     PSLAQLVKMASECNWSDPLVELQTLTRLTHFAHAARDHETTMACAHRALEMGIKYLKK
                     FGPEESRLVAEMLCTATAIQGRSIMENLKGRKQLRLVAAKAFTESARFGGIAGSSALV
                     MLAARHYWNAWLPLLSSAVYRKKAKGALKRLIGIINKTEARKQEKGKTLLLHQWPTAD
                     FQGGGTTEGYFLPGAEDDLALRAALYGLLFHSHADQDDWEGGLKVLDEAVQVLPRTAH
                     RLLIFKHMVIVKAKLGQNFSMEIQKFKAESEDYLARMWHRLALNSPSVSGELACYNNA
                     IQALQKPEMEWQKVEYLMEFGQWLHHRHFPLEDVVFHLRWAVEILLAMKPPGDVPEPQ
                     PTPDGEYVAVEMPPRSPVSEAEEAVSLEQLRSVRQLEALARVHILLALVLSPGAEGYE
                     DCCLAAYAFFRHIWQVSLMTAGKSVLENRPLAATSSHLLLPKKEKENERSKEKEKERS
                     KEKENERSKEKDKEKGKEEKVKEPKQSQSPAPIKQLEDLPMSIEEWASYSCPEEVLSV
                     LKQDRSDSTVNPSSIQKPTYSLYFLDHLVKALQKMCLHELTVPVLQLGVLISDSVVGS
                     KGLSDLYHLRLAHACSELKLREAAARHEEAVGQVCVSELEQASCRKEIALKKEKNKEP
                     LLEESLPALNEQTLPVQPGEIKPLDAKDKILKMNGETGRDLDGTSFPHLWMLKAEVLL
                     EMNLYQPARLLLSEAYLAFQELDEPCAEAQCLLLLAQLANKEKNYGQAKKMIAQAQHL
                     GGSEEFWYNSTLTLAEALLSMEHSGREATVCHIFQKLINAFKILKKERPNRLPLLEFM
                     ITDLEARCLSLRVRVAQHSAVTEPTECSLLLKEMDDGLLEIERKFIDCGCKENCVDVK
                     LERAKIKRLRAQNEKDEEQKTAYYLEAYGLAQGAVAEEEGRLHSIQGLYGLAQGAMAE
                     EEGRLHSVQGLLSLQDLQNVNTPLMRKLARLKLGLVEMALDMLQFIWEEAHGQQSEQG
                     SLEKLLADYLQNTSDYTSVGLQWFTLKRTLAHGALAQLGSLQPLSVGCVEIRARLLGL
                     AGRALHLLAMQADPVHPTCYWEAGPSVGAKLSGLKSLELEVEEEGATKSSRDPPASRA
                     APEEHCRRGEDLKRRMVLAQQYLAQASEVLLQCLQVALGSGLLDVAAAASLEMVECVG
                     TLDPATTCQFLALSQSCSASETMRDVLLAATANTSSSQLAALLQLQHQLRCQDRTTTS
                     LGARVEQRLAAVSKAWQNLCVTEQHFNLLNEMPPTFWILFLHLSGDRSRLYGAAYEKP
                     KFITAAKGKVQAVGGSCKVMRLAISPTAFSHLLACAQQFRKQTQAQVYSEDMALNIGS
                     EPEGLQVEEKERPVQRLSSVLGPLEELLQPLFPLLSLSKARVQTPAVVADSGKSKGKD
                     KERKTSTGQHSTVQPEVADKIVLVADRHLLELPLEGLSVFDEGTISSVSREFSLQMLW
                     NRLHKEETEGGVKKEGRSRDPKKRSLAKKGRKGSIPRTIPPDCIIVDSDNFKFVVDPY
                     EEAQGPEMLTPVSITQDILERFQDTFTSRWAGHLGSKHFPSQAQWEQALGSCSGFFFY
                     GMESFLSHILVERLVAMNLQECQVAVLLDLARSYQSLKRHMESVEHRRSVGRWEANWR
                     NSASPSEDEWRRGGEPRRGFSDLEGQAAAAPKLRAPSHHAQLGPVWAAAPSHRVVQAW
                     TCLPSAAGAPALASALGSAPLPTHPHLPAPIPSSQLALPFLGLSPALGAASARDPPPA
                     TSRKAAAWTSSSACLCAPWGLRRGWSCVSSRGQDKGGLPLAALVLSCLDQKTIQTVSL
                     FLI"
     exon            136..260
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            261..392
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            393..457
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            458..622
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            623..746
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            747..841
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            842..952
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1052
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1151
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1342
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1571
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1572..1692
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1693..1816
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1817..1944
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2072
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            2073..2206
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2419
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            2420..2585
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            2586..2735
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            2736..2843
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            2844..3010
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3142
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3143..3305
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3306..3390
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3391..3529
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3530..3713
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3714..3885
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            3886..4091
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4092..4298
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4299..4448
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4449..4597
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4598..4696
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4697..4829
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4830..4976
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            4977..5177
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            5178..5284
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            5285..5461
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            5462..5660
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            5661..5849
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            5850..6038
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6039..6173
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6174..6353
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6354..6524
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6525..6622
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6623..6699
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6700..6830
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6831..6952
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            6953..7035
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7036..7203
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7204..7274
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7275..7335
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7336..7371
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7372..7474
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7475..7587
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7588..7669
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7670..7750
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     exon            7751..8263
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8246..8251
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /note="hexamer: AACAAA"
     polyA_site      8263
                     /gene="CFAP46"
                     /gene_synonym="bA288G11.4; bA288G11.5; bB137A17.2;
                     bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93;
                     TTC40"
                     /note="major polyA site"
ORIGIN      
        1 cctcgcggct ggagaaccca accgacagtg ggcggcagga cgcaccgcgg accccggaga
       61 gagcggacga gcagggcgcc ggcgccatgg acctggtcat cacgcaggag ctggcccgcg
      121 ccgagagcca gcaagatgct gcgtccttga agaaggccta cgagttgatc aaatcggcca
      181 acctagggaa atcggagttt gacccctcag agagcttcag cccagacctg tttgttctgt
      241 gtgcagagca ggccctgaag atgaggcagc cagaggtgag cgaggactgc atccaaatgt
      301 acttcaaggt gaaggcgccc atcacccagt ttctgggccg agcgcacctg tgcagggccc
      361 agatgtgtgc cccgaagtcg gcagaaaacc tggaggaatt tgaaaattgc gtgactgagt
      421 acatgaaggc cataaacttt gccaaaggag aaccgaggta ctactttttg gtgtacaatg
      481 catcagtcct ctactggcag atggtgaggc cgttcctcaa gcctggatat cgtcaccatc
      541 tgatccccag cctttcccaa atcataaacg tgctgagtca gactgaggag gaagacaagg
      601 agtggcgtgc tgagctgatg ctggaacttc tggagtgtta tctgcaagcc ggaagaaagg
      661 aggaggctgc caggttctgc tccacggcag ctccgttcat taagtctcac gtgccacaga
      721 aataccggca gatattctct gttatggttc gtcatgaatt aatggacgaa cttcagttaa
      781 aggaagaaaa gaaaaattcc attagcctgt cagtcacttt ctatattaat atgctaaagg
      841 caaaagcgga gcaaaatgat ttaccaggtg acatcagtgt cattctgagg aaggcctaca
      901 gacacttagg tcattacaac caccagcgct ttccctctat cagtgaagaa aaaatgcttt
      961 tgctttttga attggcgcgt ttttccttga ccttgaaatg catggagatc tcctctgcct
     1021 gcctctcaga cctgaagaag atggaaagca aagatcctgg gaagcttatt gaaatggaat
     1081 gtctggagtg tgaatcggaa gctttaagac ttgaaagtaa gatgaaagtg tacaaccgag
     1141 cggctgttga ggcccagctg gatatcatac agaggctaga cgtcgcgctg cagcgagccg
     1201 tgcgcctggg cgacccccgg gtcatccacg tggtgtgcgc cacgcagtgg aacacctgcc
     1261 tgcccctgct gcagcacaac ctgcggcacc acctgcggaa gcccctggct ggcgttgcgg
     1321 acgtgctgga gaagctggac agcctcatga cgcttctccg ctgtcaagtg cacatggaga
     1381 tggcgcagat cgaggaggac gaggaccggc tggagcccgc cacggagcac ctccggaaag
     1441 ccgcgcgcct ggacagcctg ggcctctacc gggacaggat ccagatggcc tccacccggc
     1501 tgcgtctgtg caccacgcta taccaggccc ctgagcgcgc agaggacaag gccatcatgg
     1561 ccgttgagca ggcaaaaaaa gctacaccaa aggacagcgt caggaagaag cgggccctcc
     1621 tggtgaatgc aggcctggcc ttagcccctg acgcgtttca gattgtgctg gacagtgaga
     1681 atgaggccaa agtctccacc gggaagaaca ggggccggtt cacctacctc tgtgcgaagg
     1741 cgtggcacca caccgtcagc gtggacaaag ctgccgggca cctgcggcgc ctgggcaacg
     1801 aaaacgacaa ggagaggata cagatttggg cagagctggc caaagtggcc cggaaacaag
     1861 gcgtgtggga cgtctgtcgg acggcgagcc gcttctgcct cctgtatgac aacgtcaagg
     1921 tgaagaagtt gaggctgcgg cgagggaaga agaagcgagg tagggacggc tcggtgcagg
     1981 acacctggag ccagcctgag gtcgtcctgc agaggcaggt gtgccccgac ctgctgcgga
     2041 agttcgcgga ggtggggttc atccatgctg aggccacggt tcatttgctg cggtcagaag
     2101 gtgtagagct gaatgaccgg gccatccccc ccgaagacct gagccagcac ccagctggct
     2161 acgtgcctga gcccccggag gtgaatgctg agtggatcac atacagaacc tggatcgaga
     2221 gtctgtcccg gtgtgccatg aataactggc tgcgctccgc agagatcgga caggagatcc
     2281 aggaggcgtg gattgtgcag aacgccgtgg tctacgtcct gaaccacaac caccacctga
     2341 tcctggccgg gcggcagaag gagctggtgg acgccctgta ccacctcctg agcatcgtta
     2401 aggccacagg ccacagtggg gaccccgtga tgctggtgac gctctgcaac accttggcgc
     2461 gaggcctgat catcagctgg attccagtcc aggctgccga gaagtccagg aaattcatgc
     2521 gaccaaacgc gtttcacagc ccactggacg caggagccac ttccgagatc aaaacagcgg
     2581 tggaggtctg cgagtttgcc ctgaacctga ccaatgggag tgcgcccgag gagacggtgc
     2641 ccaccggcac ccggcagcag cttatcgcca cctgggtcaa ggccaagcag ctgctgcagc
     2701 agcagattgg gccacggctg ggcaccgagg agcagggcac caatgaggat gtcagctcgg
     2761 tgaccagagt cctcgttgcc ttggaaatgt actcatgcaa cgggctgggc ctcatggact
     2821 tcactgtccc ctccctggcc cagttggtga aaatggcttc cgagtgcaac tggtcggacc
     2881 ccctggtgga gctgcagacc ctgacgcggc tgacccactt cgcccatgca gcgcgtgacc
     2941 atgagaccac catggcctgt gctcacaggg ctctggagat gggcatcaag tacctgaaga
     3001 aatttgggcc cgaggagtcc cggctggtgg cagagatgct gtgcacagcc acggccatcc
     3061 agggcaggag catcatggaa aacctgaagg gccggaagca gctgcgactg gtggcagcca
     3121 aggccttcac ggagagcgcc aggttcggag gcatcgcggg cagcagcgcc ctggtgatgc
     3181 tggccgcgcg gcattactgg aacgcctggc tcccactgct gtcctcagcc gtctacagga
     3241 agaaggccaa gggtgccctg aagaggctca tcggcatcat caacaagaca gaggccagaa
     3301 agcaggagaa aggaaagacg ctgcttctgc accagtggcc cacggccgac ttccagggtg
     3361 gcgggacgac cgaaggatat tttcttccag gggctgagga cgacctggcg ctccgtgctg
     3421 cgctctacgg cctgctcttc cacagccatg ccgaccagga cgactgggag ggcggcctca
     3481 aggtgctgga cgaggctgtg caggtgctgc caaggacggc ccaccgcctc ttgatcttca
     3541 agcacatggt catcgtgaag gccaagctcg ggcagaattt ttcgatggaa atacagaaat
     3601 tcaaggccga gagtgaggac tacttggcgc gcatgtggca ccgcctggcc ctgaactcgc
     3661 cgagcgtgtc tggagagctg gcctgctaca acaacgccat ccaggccttg cagaagcctg
     3721 agatggagtg gcagaaggtg gagtacctca tggagttcgg ccagtggctc catcacagac
     3781 actttcctct cgaggacgtg gtcttccacc tccgctgggc tgtcgagatc ctgctggcca
     3841 tgaagccgcc cggcgatgtc cctgagccac agcccacgcc ggatggggag tacgtggctg
     3901 tggagatgcc cccacggagc cccgtgtccg aggccgagga ggcggtgtcc ttggagcagc
     3961 tgcgtagcgt gcggcagctg gaggcgctgg cccgcgtgca catcctgctg gccctggtgc
     4021 tgtcgccggg cgccgagggc tacgaggact gctgccttgc agcctacgcc ttcttcaggc
     4081 acatctggca ggtttctttg atgacagcag gaaaatcagt tctggaaaac agacccctgg
     4141 cagcaaccag ctcacatctg ttattgccta aaaaagagaa ggagaatgag aggagtaaag
     4201 agaaggagaa ggagaggagt aaagagaagg agaatgagag gagtaaagag aaggacaagg
     4261 agaagggaaa ggaggagaaa gtcaaggagc ccaagcagtc tcaaagccca gctcctatca
     4321 aacaactgga agacttaccc atgagcatag aagagtgggc ttcctactcc tgccccgagg
     4381 aagtgctgtc tgtactgaaa caggacagaa gtgactctac tgtgaacccc tcaagtatcc
     4441 agaagccgac atacagtttg tatttcctgg accacctggt caaggccctg cagaagatgt
     4501 gcctgcacga actcacggtt cccgtcctgc agttgggggt gctgatttcg gactccgtgg
     4561 tgggaagcaa gggcctgtcg gatctctacc accttcgcct cgcccacgcg tgctccgagc
     4621 tgaagctgag agaagcagcc gcgcgccatg aagaggcggt cgggcaggtg tgcgtcagcg
     4681 agctggagca ggccagctgc agaaaagaga tcgcgttgaa aaaagagaaa aataaggagc
     4741 ctttattaga agaaagcctg ccagcactga atgagcagac acttcctgtc cagcctgggg
     4801 agatcaaacc actggacgcc aaggacaaga ttttgaagat gaatggggag accgggaggg
     4861 acctggatgg gacgtccttt ccccacctgt ggatgctgaa ggcagaagtt ctgctggaga
     4921 tgaacctgta ccagcctgca cggctgctcc tgtcggaggc ttacctggct ttccaggagc
     4981 tggatgagcc ttgtgcagag gcccagtgcc tgctcctcct cgcacagttg gccaacaagg
     5041 agaaaaacta tggacaagcc aagaaaatga tcgcacaggc ccagcacctg ggcggaagtg
     5101 aggagttctg gtacaattcc actctgaccc tggcagaggc gctcttgtcc atggaacact
     5161 caggaaggga agctacggtg tgtcacatat ttcagaagct catcaatgcc ttcaagatcc
     5221 tcaagaaaga aagaccaaac cgattgcctt tactggaatt catgatcaca gatctagaag
     5281 ccaggtgcct gagcctgcgg gtcagagttg cgcagcactc agcggtcact gaacccacag
     5341 agtgctcgtt gctactgaaa gagatggatg atggcctgtt ggaaattgag agaaagttta
     5401 tcgactgtgg ctgcaaagag aattgtgttg acgtaaaact agagcgtgcg aagatcaaga
     5461 ggttacgtgc ccagaacgag aaagatgaag aacaaaaaac tgcgtattac ttggaagcgt
     5521 atggcctggc ccagggtgcc gtagctgagg aagaagggag gcttcacagc atccagggct
     5581 tatatggcct ggcccagggc gccatggctg aggaagaagg gaggcttcac agcgtccagg
     5641 gcctattgtc acttcaagac ttgcagaacg tcaacacgcc cctgatgagg aagctggcgc
     5701 gcctcaagct cggcctcgtg gaaatggctc tggacatgct ccagttcatc tgggaggagg
     5761 cccacgggca gcagagtgag caggggtccc tggagaagct gctggcggac tatctgcaga
     5821 acaccagtga ctacacttcc gtcggcctgc aatggttcac gctgaagcgg actctagcac
     5881 acggggcact ggcacagctg gggagcctgc agccgctgag cgtgggctgt gtggagatcc
     5941 gcgcccggct cctgggcctg gccgggaggg ccctgcacct gctggccatg caagctgacc
     6001 ctgtgcaccc tacctgctac tgggaggcgg gcccctcggt gggcgccaag ctgagcggcc
     6061 tcaagtctct ggagctggag gtagaggaag agggtgccac aaagtccagc agggacccgc
     6121 cggcctccag ggcagccccg gaggagcact gcaggagagg cgaggacctg aagaggagga
     6181 tggttctggc ccagcagtac ctggctcagg cgtcagaggt gctgctgcag tgcctacagg
     6241 tggcccttgg cagtggcctc ctggatgtcg cagcagccgc cagcctggag atggtggagt
     6301 gtgtcggcac cctggaccct gcaactacct gccagttcct ggctctgtct cagagctgct
     6361 cggcctcaga gacgatgagg gatgtcctgc ttgcagccac agccaacacc agcagctcac
     6421 agctggcggc cctgctgcag ctacagcacc agctccggtg ccaagacagg accaccacca
     6481 gcctgggcgc ccgtgtggag cagaggctgg ccgccgtgtc caaggcttgg caaaatctct
     6541 gcgtcactga gcagcatttt aacctcttga atgagatgcc tccgaccttt tggatcctct
     6601 ttctgcacct ctcaggggac aggtcccgtc tgtacggcgc tgcctacgag aaacccaagt
     6661 tcattactgc agccaaagga aaggtgcagg cggtgggagg ctcctgcaag gtgatgcgtc
     6721 tggccataag tcccactgcc ttctcccacc tgctggcctg tgcccagcag ttccggaagc
     6781 agacccaggc ccaggtgtac agtgaggaca tggccctgaa cataggctcg gaaccagaag
     6841 gcctgcaggt ggaagagaag gagcgccctg tgcagaggct cagtagcgtc ctggggcccc
     6901 tggaggagct tctgcagccg ctattccccc tgctcagcct ctccaaggcc agagtgcaga
     6961 cacctgcggt tgttgccgat tcagggaagt cgaagggcaa agacaaggag aggaaaacgt
     7021 ccacaggaca acacagcaca gtccagcctg aggttgccga taagatagtc ctggtcgcag
     7081 acagacatct cctggagctg ccactggaag gtctctctgt gttcgatgaa gggacaattt
     7141 cctctgtgtc acgagaattt tctcttcaaa tgctgtggaa tcgcctccat aaagaagaga
     7201 cagaaggtgg cgtgaaaaag gagggaagaa gcagagaccc caaaaagaga agcctagcga
     7261 agaagggcag gaagggcagc atcccccgga ccatcccccc tgactgcatc atagtcgact
     7321 cagacaactt caagttcgtc gtggacccat acgaggaggc ccagggccca gaaatgctaa
     7381 ctcctgtctc catcacccaa gacattttgg aaagattcca agacacattc acgtcgcgat
     7441 gggcgggaca tctgggaagc aagcactttc ccagccaggc ccagtgggag caggccctgg
     7501 gcagctgcag cggtttcttc ttctatggaa tggagagctt cctgtcccat atattagtgg
     7561 agagattggt cgccatgaac ttgcaagagt gccaggtggc agtcctgctg gacctggcgc
     7621 ggtcctacca gagcttgaag aggcacatgg agagcgtgga gcacaggaga tctgttggcc
     7681 gttgggaagc caattggaga aacagtgcgt ctccttcaga agatgagtgg cgacgaggcg
     7741 gtgaaccaag acgaggcttc tcagaccttg aaggacaagc tgctgctgct ccaaagctcc
     7801 gagctccttc ccaccacgct caacttggtc ctgtatgggc tgccgcacca agccatcggg
     7861 tagtgcaggc ctggacctgc ctcccatcag ctgctggggc cccagcactt gcctctgccc
     7921 ttggctctgc ccctctgcca acccatcccc acctcccggc tcccatcccc agctcccagc
     7981 tcgctctccc cttcctgggc ctctccccag cccttggtgc agcctcagcc agggaccctc
     8041 ccccagcgac ttcccgcaag gcagccgcct ggacctcgag ctctgcctgc ctgtgtgcgc
     8101 catggggtct gcgtcggggc tggagctgcg tctcttcccg gggccaggac aagggcggcc
     8161 tccccttggc ggcgctggtg ctgagttgct tagaccagaa gactattcag accgtgagcc
     8221 tgtttttgat ttgagtgttc cactaaacaa acaacaaaag cca
//
