LOCUS       NM_025145               5367 bp    mRNA    linear   PRI 09-JUN-2024
DEFINITION  Homo sapiens cilia and flagella associated protein 43 (CFAP43),
            mRNA.
ACCESSION   NM_025145
VERSION     NM_025145.7
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5367)
  AUTHORS   Khan,I., Shah,B., Dil,S., Ullah,N., Zhou,J.T., Zhao,D.R.,
            Zhang,Y.W., Jiang,X.H., Khan,R., Khan,A., Ali,H., Zubair,M.,
            Shah,W., Zhang,H. and Shi,Q.H.
  TITLE     Novel biallelic loss-of-function mutations in CFAP43 cause multiple
            morphological abnormalities of the sperm flagellum in Pakistani
            families
  JOURNAL   Asian J Androl 23 (6), 627-632 (2021)
   PUBMED   34100391
  REMARK    GeneRIF: Novel biallelic loss-of-function mutations in CFAP43 cause
            multiple morphological abnormalities of the sperm flagellum in
            Pakistani families.
REFERENCE   2  (bases 1 to 5367)
  AUTHORS   Li,L., Feng,F., Wang,Y., Guo,J. and Yue,W.
  TITLE     Mutational effect of human CFAP43 splice-site variant causing
            multiple morphological abnormalities of the sperm flagella
  JOURNAL   Andrologia 52 (6), e13575 (2020)
   PUBMED   32207550
  REMARK    GeneRIF: Mutational effect of human CFAP43 splice-site variant
            causing multiple morphological abnormalities of the sperm flagella.
REFERENCE   3  (bases 1 to 5367)
  AUTHORS   Morimoto,Y., Yoshida,S., Kinoshita,A., Satoh,C., Mishima,H.,
            Yamaguchi,N., Matsuda,K., Sakaguchi,M., Tanaka,T., Komohara,Y.,
            Imamura,A., Ozawa,H., Nakashima,M., Kurotaki,N., Kishino,T.,
            Yoshiura,K.I. and Ono,S.
  TITLE     Nonsense mutation in CFAP43 causes normal-pressure hydrocephalus
            with ciliary abnormalities
  JOURNAL   Neurology 92 (20), e2364-e2374 (2019)
   PUBMED   31004071
  REMARK    GeneRIF: A loss of function mutation was identified in a family
            with normal-pressure hydrocephalus.
REFERENCE   4  (bases 1 to 5367)
  AUTHORS   Wu,H., Li,W., He,X., Liu,C., Fang,Y., Zhu,F., Jiang,H., Liu,W.,
            Song,B., Wang,X., Zhou,P., Wei,Z., Zhang,F. and Cao,Y.
  TITLE     NovelCFAP43 andCFAP44 mutations cause male infertility with
            multiple morphological abnormalities of the sperm flagella (MMAF)
  JOURNAL   Reprod Biomed Online 38 (5), 769-778 (2019)
   PUBMED   30904354
  REMARK    GeneRIF: important cause of multiple morphological abnormalities of
            the sperm flagellum in the Chinese population
REFERENCE   5  (bases 1 to 5367)
  AUTHORS   Sha,Y.W., Wang,X., Xu,X., Su,Z.Y., Cui,Y., Mei,L.B., Huang,X.J.,
            Chen,J., He,X.M., Ji,Z.Y., Bao,H., Yang,X., Li,P. and Li,L.
  TITLE     Novel Mutations in CFAP44 and CFAP43 Cause Multiple Morphological
            Abnormalities of the Sperm Flagella (MMAF)
  JOURNAL   Reprod Sci 26 (1), 26-34 (2019)
   PUBMED   29277146
  REMARK    GeneRIF: Study demonstrated that biallelic mutations in CFAP44 and
            CFAP43 cause multiple morphological abnormalities of the sperm
            flagella (MMAF). These results provide researchers with a new
            insight to understand the genetic etiology of MMAF and to identify
            new loci for genetic counselling of MMAF.
REFERENCE   6  (bases 1 to 5367)
  AUTHORS   Coutton,C., Vargas,A.S., Amiri-Yekta,A., Kherraf,Z.E., Ben
            Mustapha,S.F., Le Tanno,P., Wambergue-Legrand,C., Karaouzene,T.,
            Martinez,G., Crouzy,S., Daneshipour,A., Hosseini,S.H., Mitchell,V.,
            Halouani,L., Marrakchi,O., Makni,M., Latrous,H., Kharouf,M.,
            Deleuze,J.F., Boland,A., Hennebicq,S., Satre,V., Jouk,P.S.,
            Thierry-Mieg,N., Conne,B., Dacheux,D., Landrein,N., Schmitt,A.,
            Stouvenel,L., Lores,P., El Khouri,E., Bottari,S.P., Faure,J.,
            Wolf,J.P., Pernet-Gallay,K., Escoffier,J., Gourabi,H.,
            Robinson,D.R., Nef,S., Dulioust,E., Zouari,R., Bonhivers,M.,
            Toure,A., Arnoult,C. and Ray,P.F.
  TITLE     Mutations in CFAP43 and CFAP44 cause male infertility and flagellum
            defects in Trypanosoma and human
  JOURNAL   Nat Commun 9 (1), 686 (2018)
   PUBMED   29449551
  REMARK    GeneRIF: demonstrate that CFAP43 and CFAP44 have a similar
            structure with a unique axonemal localization and are necessary to
            produce functional flagella in species ranging from Trypanosoma to
            human
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5367)
  AUTHORS   Tang,S., Wang,X., Li,W., Yang,X., Li,Z., Liu,W., Li,C., Zhu,Z.,
            Wang,L., Wang,J., Zhang,L., Sun,X., Zhi,E., Wang,H., Li,H., Jin,L.,
            Luo,Y., Wang,J., Yang,S. and Zhang,F.
  TITLE     Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility
            with Multiple Morphological Abnormalities of the Sperm Flagella
  JOURNAL   Am J Hum Genet 100 (6), 854-864 (2017)
   PUBMED   28552195
  REMARK    GeneRIF: biallelic mutations in either CFAP43 or CFAP44 can cause
            sperm flagellar abnormalities and impair sperm motility.
REFERENCE   8  (bases 1 to 5367)
  AUTHORS   Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
            Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
            Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
            Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
            Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
            Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
            Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am J Hum Genet 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   9  (bases 1 to 5367)
  AUTHORS   Lesch,K.P., Timmesfeld,N., Renner,T.J., Halperin,R., Roser,C.,
            Nguyen,T.T., Craig,D.W., Romanos,J., Heine,M., Meyer,J.,
            Freitag,C., Warnke,A., Romanos,M., Schafer,H., Walitza,S., Reif,A.,
            Stephan,D.A. and Jacob,C.
  TITLE     Molecular genetics of adult ADHD: converging evidence from
            genome-wide association and extended pedigree linkage studies
  JOURNAL   J Neural Transm (Vienna) 115 (11), 1573-1585 (2008)
   PUBMED   18839057
REFERENCE   10 (bases 1 to 5367)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL139341.9 and AL357336.11.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Dec 17, 2019 this sequence version replaced NM_025145.6.
            
            Summary: This gene encodes a member of the cilia- and
            flagella-associated protein family. [provided by RefSeq, Sep 2016].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC071565.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000357060.8/ ENSP00000349568.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               AL139341.9         62924-63106         c
            184-437             AL139341.9         61332-61585         c
            438-534             AL139341.9         56203-56299         c
            535-702             AL139341.9         45001-45168         c
            703-853             AL139341.9         42749-42899         c
            854-1013            AL139341.9         38407-38566         c
            1014-1081           AL139341.9         36705-36772         c
            1082-1213           AL139341.9         34414-34545         c
            1214-1330           AL139341.9         28664-28780         c
            1331-1411           AL139341.9         27595-27675         c
            1412-1560           AL139341.9         24608-24756         c
            1561-1664           AL139341.9         22941-23044         c
            1665-1805           AL139341.9         19012-19152         c
            1806-1978           AL139341.9         18062-18234         c
            1979-2128           AL139341.9         16716-16865         c
            2129-2259           AL139341.9         15758-15888         c
            2260-2407           AL139341.9         13108-13255         c
            2408-2500           AL139341.9         10582-10674         c
            2501-2578           AL139341.9         9771-9848           c
            2579-2704           AL139341.9         3152-3277           c
            2705-2809           AL357336.11        52213-52317         c
            2810-2926           AL357336.11        51090-51206         c
            2927-3157           AL357336.11        49957-50187         c
            3158-3364           AL357336.11        47563-47769         c
            3365-3451           AL357336.11        45786-45872         c
            3452-3532           AL357336.11        45430-45510         c
            3533-3658           AL357336.11        44506-44631         c
            3659-3778           AL357336.11        36076-36195         c
            3779-3886           AL357336.11        31360-31467         c
            3887-3973           AL357336.11        29732-29818         c
            3974-4062           AL357336.11        28945-29033         c
            4063-4276           AL357336.11        26895-27108         c
            4277-4389           AL357336.11        25750-25862         c
            4390-4549           AL357336.11        24311-24470         c
            4550-4714           AL357336.11        17089-17253         c
            4715-4795           AL357336.11        15585-15665         c
            4796-4949           AL357336.11        14800-14953         c
            4950-5367           AL357336.11        13357-13774         c
FEATURES             Location/Qualifiers
     source          1..5367
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q25.1"
     gene            1..5367
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /note="cilia and flagella associated protein 43"
                     /db_xref="GeneID:80217"
                     /db_xref="HGNC:HGNC:26684"
                     /db_xref="MIM:617558"
     exon            1..183
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..5116
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /note="WD repeat-containing protein C10orf79; WD
                     repeat-containing protein 96; WD repeat domain 96"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 43"
                     /protein_id="NP_079421.5"
                     /db_xref="CCDS:CCDS31281.1"
                     /db_xref="GeneID:80217"
                     /db_xref="HGNC:HGNC:26684"
                     /db_xref="MIM:617558"
                     /translation="MAQGRERDEGPHSAGGASLSVRWVQGFPKQNVHFVNDNTICYPC
                     GNYVIFINIETKKKTVLQCSNGIVGVMATNIPCEVVAFSDRKLKPLIYVYSFPGLTRR
                     TKLKGNILLDYTLLSFSYCGTYLASYSSLPEFELALWNWESSIILCKKSQPGMDVNQM
                     SFNPMNWRQLCLSSPSTVSVWTIERSNQEHCFRARSVKLPLEDGSFFNETDVVFPQSL
                     PKDLIYGPVLPLSAIAGLVGKEAETFRPKDDLYPLLHPTMHCWTPTSDLYIGCEEGHL
                     LMINGDTLQVTVLNKIEEESPLDRRNFISPVTLVYQKEGVLASGIDGFVYSFIIKDRS
                     YMIEDFLEIERPVEHMTFSPNYTVLLIQTDKGSVYIYTFGKEPTLNKVLDACDGKFQA
                     IDFITPGTQYFMTLTYSGEICVWWLEDCACVSKIYLNTLATVLACCPSSLSAAVGTED
                     GSVYFISVYDKESPQVVHKAFLSESSVQHVVYDQQGIFLLVGTAEGKVFIINANSSSS
                     FQIIGFTEVAKDILQISTVSLLETDIVEVMVLSSLPEAGRSRLEMFTLPTLLPQVSTT
                     FADERGRLKDEIIHKYLYELEHALSSAVLGFQSNQIYGFCSQVPYICSYLLPEEEHTG
                     IYILKPYKKVQSRQYGPGLLYLSSHGLWLITIAKCGILCIRDVYTLETFAWCRSHSHQ
                     GHGIQSMRISMDGQNILVNGRDDGTLVYLKWKRFGGHLASEILDYYQKLLISLSSAMD
                     KENHYLSTTPKVSVDLGSDSEHTKQKASTDLSQDELVLTDVKKEIPWIQQKSQEAIKK
                     EVNLFSKKRKEIKQGIKSLSKTILNMMEENDKLENIAKLDQQEFGLDLEELERLHDES
                     QEEVAKMIKDVEMHNLAKSYLAELIKEECWNSMAVKGRALKCFHIPCVVENFPMKART
                     VEELKELERVLQQKKIEAECLKLRKEIVEAQSGVKLIKQRHEEDDEEEEEEDKTVKYS
                     NLPNYLLGSLSTDFGVDTSLLSSQLELHSREEKINQIILLKDIIYKVKTVFNNEFDAA
                     YKQKEFEIARVKERNVRIREIILDLELEEAVWQPEFEDCEKPERTLVVQDEEITAHKH
                     IKPWHKAKELIVNHEKEHWLLIQDASTRLRALMDMMGGVLEVKKEDILRMVIPQPAFM
                     AKPDAVWTEEERKQFKDYEKKVKELNEERDKYRKSLEAELKKLQNSIQESTQAFDEHL
                     KRLFERRVKAEMVTNQEELKISNLAFSLLLDEELSSREKFLNNYLTRKQHEKSQTSEA
                     VRKSREDLDVCKEHYDNLLAEDKVMDRSFKKEFSEIPGHQVDILYKLFKRRPRISKQK
                     THSETTSVVPFGELPGSGKLNKDAFAQLMKAMDELDNISNMPEGLDPLVWNHFCMTRR
                     AKVENEQKVKQKAADLLEMATFLQKRVEEEEKVQQEIERVFHELILLQEEKVRFQLNL
                     TIQILLKQGQVELENFQLVLEYSDAILINKNIIEDLNSVIRTQGQKKVASMMESKDVH
                     KRILQIEWEHKKMEMEREDLNQKAWDIQMLFFSRDRQKYLNEPNYEALISIQIGIMEQ
                     TIAVLDKMHKKNVENCKKLLKKLGKFSNQKDIANYALSCNLREELVAVSERKDICNAM
                     GSKLTCEKIVKERYENMMQQQKLTNISKQQAEQISILQTEVERLRMKTFPALVQM"
     exon            184..437
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            438..534
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            535..702
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            703..853
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1013
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1081
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1213
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1330
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1411
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1560
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1664
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1805
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1978
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            1979..2128
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2259
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2260..2407
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2500
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2501..2578
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2579..2704
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2809
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2810..2926
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            2927..3157
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3158..3364
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3365..3451
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3532
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3533..3658
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3659..3778
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3779..3886
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3887..3973
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            3974..4062
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4063..4276
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4277..4389
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4390..4549
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4550..4714
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4715..4795
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4796..4949
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     exon            4950..5367
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5298..5303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /note="hexamer: AATAAA"
     polyA_site      5317
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /note="major polyA site"
     regulatory      5340..5345
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /note="hexamer: AATAAA"
     regulatory      5344..5349
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
                     /note="hexamer: AACAAG"
     polyA_site      5360
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
     polyA_site      5367
                     /gene="CFAP43"
                     /gene_synonym="bA373N18.2; C10orf79; HYDNP1; SPGF19;
                     WDR96"
ORIGIN      
        1 atacgggtgt acacagcagc ggcgtcgcgg cccgcagccc cgcggcggcg gaaaggtaac
       61 cgacccgccc tggggtgctg cgtgcgctgc ctgctcccgc ctgaggaaaa cactgcccat
      121 ggcgcaaggc cgggagcgcg acgaaggccc ccactccgcc ggcggcgcgt ccttgtccgt
      181 gagatgggtg caaggattcc ctaagcagaa tgttcatttt gtcaacgaca acaccatttg
      241 ctacccttgt gggaattatg taatatttat taatattgaa accaagaaaa agactgtact
      301 gcagtgtagt aatggaattg tgggcgtcat ggcaactaac atcccctgtg aagttgtggc
      361 tttttctgac cggaagctaa aacctctcat ctacgtatac agctttccag gattgaccag
      421 aaggaccaaa ttgaaaggca acattctcct ggactacact ttactttcat tcagttactg
      481 tggcacctac ctggctagtt actcctctct cccagaattt gaactggccc tttggaactg
      541 ggaatcgagt atcattttgt gtaagaaatc acagcctgga atggatgtga accaaatgtc
      601 ttttaacccc atgaactggc gccagctgtg cttatcaagt ccaagtacag tgagcgtgtg
      661 gaccattgaa agaagtaacc aggagcattg tttcagagca aggtcggtga aattacctct
      721 agaagatggg tcatttttta atgaaacgga tgtcgttttc ccccagtcgt tgccgaaaga
      781 tctcatctat ggtcccgtgc tgccactgtc agccattgcc gggctggtag gcaaagaggc
      841 agagactttc cggccgaaag atgatctata tcctttgctt cacccgacta tgcattgctg
      901 gactccaaca agtgacttgt acattggctg tgaagagggt catcttttaa tgattaatgg
      961 agacaccttg caagtgactg tacttaataa gatagaagag gaatcgccat tggacagaag
     1021 aaattttatc agtccagtaa ccttggtata tcagaaggag ggcgtgctgg cttctggaat
     1081 tgatggcttt gtgtattctt ttattattaa agatagaagt tacatgatcg aggattttct
     1141 tgagattgaa agacctgtag aacatatgac attttctccc aattatacag tgttgctgat
     1201 tcaaacagac aagggatctg tttatatcta cacttttggt aaggagccaa ccttaaataa
     1261 agtcctagat gcttgtgatg ggaaatttca ggcaattgac tttatcacac ctggaaccca
     1321 atacttcatg acacttacat attcagggga aatttgtgtt tggtggctgg aggattgtgc
     1381 ttgtgtaagc aagatttatc tgaataccct agcaacggtt ctggcttgct gtccatcctc
     1441 cctctctgca gccgtgggca cggaggatgg ctcggtctac ttcatcagcg tatatgataa
     1501 ggaatcccct caggtcgtgc acaaggcctt tctctcggaa tcgtccgtgc agcacgtcgt
     1561 ttatgatcag caaggaatat ttctgttagt tggaacagca gaaggaaaag tctttattat
     1621 caatgccaac tcctcaagct catttcagat tattggattc acagaggtgg ccaaagacat
     1681 tttacagata tccacagtgt ctcttttaga aacagacata gtggaagtga tggtgctttc
     1741 ctcgcttcca gaagcaggga gaagcaggtt ggagatgttc acactgccta cattactgcc
     1801 acaagtttcc acaacctttg ctgatgaaag aggaaggctg aaagatgaaa tcattcataa
     1861 gtacctgtat gagttggagc acgctctgtc ctctgcagtc ttgggctttc aaagtaacca
     1921 aatatatggc ttctgtagtc aagtgccata catctgtagc taccttcttc ctgaagaaga
     1981 acataccggt atctacattc ttaaaccata caaaaaagta caaagcagac agtatggacc
     2041 tggactgctc tatctgtctt cacatggatt gtggctcata acaatagcta aatgtggaat
     2101 tctgtgtatc cgagacgttt atactttgga aacatttgct tggtgtcgga gtcattctca
     2161 ccagggtcat gggattcagt caatgagaat ttcaatggat ggacaaaaca ttctggtgaa
     2221 tgggagagat gatggcaccc ttgtctacct aaagtggaag cgatttggag gacacctagc
     2281 cagtgaaatt ctggactatt accagaaact attaatttcc ctgagcagcg ccatggacaa
     2341 ggagaatcat tatttaagca caacaccaaa agtttccgta gatttgggat ccgattctga
     2401 acacacaaaa cagaaggcaa gcactgactt atcacaagat gaattagttc taaccgatgt
     2461 taagaaggaa attccttgga tacaacaaaa aagccaagag gccatcaaaa aggaggttaa
     2521 tctgttttcc aagaaaagga aagagataaa acaaggaatc aaatcacttt ccaaaactat
     2581 tctgaatatg atggaagaaa atgacaaact agaaaatatt gcaaaattag accaacagga
     2641 atttggtctg gatcttgagg aactagaaag gcttcatgat gaaagtcagg aagaagtggc
     2701 aaagatgata aaggatgtag agatgcataa cttagccaag agctatttgg ctgaacttat
     2761 caaagaagaa tgttggaatt cgatggctgt gaaaggtcga gctcttaagt gttttcatat
     2821 cccctgtgtg gttgaaaact tcccgatgaa agcgcgcacg gttgaagagc tgaaagaatt
     2881 ggaaagagtt ttacagcaaa agaagattga agcagagtgt cttaaactac ggaaggaaat
     2941 tgtagaggct cagtctggag ttaagttgat taaacagcgt catgaagagg atgatgaaga
     3001 agaggaagag gaagacaaga cagtaaaata tagcaatttg cccaattacc tgcttggtag
     3061 tctgagtact gattttgggg tagatacctc tttattgtca agccaattgg agcttcattc
     3121 cagagaagag aaaatcaacc aaattatatt attgaaagat atcatttaca aggtaaaaac
     3181 tgttttcaat aatgagtttg acgctgcata taaacaaaaa gagtttgaaa ttgcacgcgt
     3241 gaaggaaaga aatgttcgaa ttcgagaaat tattttagat ctggaattgg aagaagcagt
     3301 ctggcaacca gaatttgaag actgtgagaa gccagagaga acgcttgttg tgcaagatga
     3361 ggagattaca gcccacaaac acattaagcc gtggcacaaa gccaaagaat tgatcgtgaa
     3421 tcatgaaaag gagcactggc ttctgataca ggatgccagt acaagactcc gagctctgat
     3481 ggacatgatg ggaggagttc tggaagtcaa gaaggaagat attttgagaa tggtgattcc
     3541 tcaacctgct ttcatggcaa aacctgatgc tgtgtggact gaagaagaaa gaaaacaatt
     3601 caaagattat gagaaaaaag taaaggagtt aaatgaagaa agagataagt atagaaagtc
     3661 attagaagca gaactgaaga aacttcaaaa ctctattcaa gaaagcacac aggcctttga
     3721 tgaacatttg aaaagacttt ttgaaaggag agtgaaggca gagatggtta ccaaccagga
     3781 ggaactgaaa ataagtaacc ttgcattttc tttattgttg gatgaagaat taagctctag
     3841 agaaaaattc ctgaacaact accttacaag gaaacagcac gagaaaagcc agacttcaga
     3901 agctgttcgg aaatctagag aagacctgga tgtgtgcaag gagcactatg acaacttact
     3961 ggcagaagac aaagttatgg atcgcagctt taaaaaggaa ttttctgaaa ttcctggtca
     4021 tcaagtggat atactctaca aactttttaa acgccgacca aggatttcca aacagaaaac
     4081 gcactcagaa acaaccagcg ttgtcccttt cggagaacta ccaggatctg gcaagttgaa
     4141 taaggatgcc tttgcccagt taatgaaagc tatggatgag ttggacaata ttagtaacat
     4201 gccagaaggc ttggaccctt tggtctggaa tcatttctgc atgacaagac gagcaaaagt
     4261 ggaaaatgaa cagaaagtaa agcagaaagc agctgactta ttggaaatgg caactttcct
     4321 ccagaagaga gttgaggagg aagagaaggt gcaacaggag attgagagag tgttccatga
     4381 actcatccta ttacaggaag agaaagtgag attccagttg aatttgacaa tccaaattct
     4441 tcttaaacaa ggacaagtag aactggaaaa tttccagcta gtactggagt attctgatgc
     4501 aattctcatc aacaagaaca taattgaaga cttgaattct gtgattcgga ctcaaggaca
     4561 aaagaaagtt gctagcatga tggaaagtaa agatgtacac aaaagaatac ttcagattga
     4621 gtgggaacat aagaaaatgg agatggaaag ggaagatcta aatcagaagg cttgggatat
     4681 tcagatgcta tttttttcaa gagatcgtca aaagtaccta aatgaaccaa actatgaggc
     4741 tctgattagt attcagattg gaataatgga acaaaccatt gctgttttag ataagatgca
     4801 caaaaagaat gtggaaaact gcaagaaact actcaaaaaa cttggaaagt tcagcaatca
     4861 aaaagatata gcaaattatg ccctaagctg caatctacga gaagagttgg tagctgtctc
     4921 agagagaaaa gacatctgta atgcaatggg gtctaaactg acttgtgaaa agattgtcaa
     4981 agaacggtat gaaaacatga tgcaacagca gaagttaaca aatatttcaa aacaacaagc
     5041 tgaacagatt tcaatactac agactgaagt tgaaagatta agaatgaaaa catttcctgc
     5101 tcttgttcaa atgtaaaaac gctggcagga aaacacaagg ccaaatcaat catttaaaaa
     5161 atcatttcat ttgggtaaaa tgatttcctt ttctttctta ctgggaaatt gaagtagcat
     5221 gtcctctgag ttgcatgttt tagataaaaa attgtttaat tttagcctta attgtataca
     5281 aatttttgtc ctgcatgaat aaatgtgtaa aataccatga attgctgttt ttattcaaga
     5341 ataaacaaga cttgaagtca gaaagta
//
