LOCUS       NM_153376               2153 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens cilia and flagella associated protein 184 (CFAP184),
            mRNA.
ACCESSION   NM_153376
VERSION     NM_153376.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2153)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 2153)
  AUTHORS   Bazan,R., Schrofel,A., Joachimiak,E., Poprzeczko,M., Pigino,G. and
            Wloga,D.
  TITLE     Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that
            connects radial spoke 3 to dynein g and the nexin link
  JOURNAL   PLoS Genet 17 (3), e1009388 (2021)
   PUBMED   33661892
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2153)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 2153)
  AUTHORS   Firat-Karalar,E.N., Sante,J., Elliott,S. and Stearns,T.
  TITLE     Proteomic analysis of mammalian sperm cells identifies new
            components of the centrosome
  JOURNAL   J Cell Sci 127 (Pt 19), 4128-4133 (2014)
   PUBMED   25074808
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC097382.3.
            
            On May 17, 2019 this sequence version replaced NM_153376.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1803616.115612.1, AK075056.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000310085.6/ ENSP00000309285.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2153              AC097382.3         54429-56581         c
FEATURES             Location/Qualifiers
     source          1..2153
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p16.1"
     gene            1..2153
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /note="cilia and flagella associated protein 184"
                     /db_xref="GeneID:257236"
                     /db_xref="HGNC:HGNC:26900"
                     /db_xref="MIM:619347"
     exon            1..2153
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..1731
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /note="coiled-coil domain-containing protein 96;
                     coiled-coil domain containing 96"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 184"
                     /protein_id="NP_699207.1"
                     /db_xref="CCDS:CCDS3395.1"
                     /db_xref="GeneID:257236"
                     /db_xref="HGNC:HGNC:26900"
                     /db_xref="MIM:619347"
                     /translation="MDVSSEHTKDPGGEGGDGESLAARPSKIKASSGPPTSPEPGELE
                     SEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAE
                     VGAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEA
                     ETERVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLYGRDEFEDLEWSEEVQK
                     LQEQQLRSDLLDQYRSLLVERNRSQRYNLYLQHKIFEALRRKKGLEAAEVADRGAEAE
                     APEKEQAYLRHLGMLEELKKQQADDLQWYHQELGQLKRQCQEKLTRVEKEWRRFQALK
                     KQVVMQAMGSCRMRGGRQAALREVEQIQALEDKKEKEMSAVRLENIQLKQSLVHFETR
                     MRTQEDLTQGLLLIDFEQLKIENQTFNEKIEERNEELLKLRSKVTNSVQVITHVKEKL
                     HFMDMENACKKTQLAEIEAQAALGRDILTKTKQAREGLRTDNIRLNQKCGLLGKDSLL
                     RDLEEKVDKTELLHRRLESLKRHHASLTLSCRGVRQKIREAKAFLPS"
     regulatory      1808..1813
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /note="hexamer: ATTAAA"
     polyA_site      1833
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /note="major polyA site"
     regulatory      2130..2135
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /note="hexamer: ATTAAA"
     polyA_site      2153
                     /gene="CFAP184"
                     /gene_synonym="CCDC96"
                     /note="major polyA site"
ORIGIN      
        1 gttgccccgg gaaacctaac agcgtcctgc cggggtccgc tgcgctggcc gagccgggag
       61 gagatggacg tcagctctga gcacactaag gaccccggcg gggaaggcgg agacggggaa
      121 agcctggccg cgcggccgtc caagatcaag gccagctctg gccctccgac ctctcccgaa
      181 cccggggagc tggagtcgga gccggaggag gaggaggagg agcaagcggc ttcgcaggga
      241 ggcaccgccg cggacgagca ggccgaggcc ccgaaagggc taacggcagc cgaggctgcg
      301 ggcgaggagg ggcctggaga gccggggagg ccggccgagc cccagcccga gcccgaagag
      361 ccggccgagg ttggggctga ggagcccgcc cagccggagc ccggagccgg gcccgaggaa
      421 ctagaggcgg aggcgggggc ggaggaactg gagcaggcgg cagaggggaa ggaagtcagg
      481 ttccaggcct ctctgccgct gaccaggatc gatgaggaag aggctgctgc agccccggag
      541 gccgagacag agcgggtgga gggggaggaa gaggacaagg aggagacgca gagagacggc
      601 gcggagagca aggagaggga tggggaagga cgcccggcca aaagccagga agaggggaag
      661 cgcctctatg gaagggacga gtttgaggac ctcgagtggt ccgaggaggt ccagaagctg
      721 caggagcagc agctgcgcag cgacctcctg gaccagtacc gttccctgct ggtggagcgg
      781 aaccgctccc agcgctacaa cctatacctg cagcacaaga tcttcgaggc gctgcgcaga
      841 aagaagggcc tggaggccgc tgaggtggct gaccggggcg cagaggccga ggcccccgag
      901 aaagagcaag cgtacctgcg ccatctgggc atgctggagg agctgaagaa gcagcaggca
      961 gacgacctgc agtggtacca ccaggagctg ggccagttga agcggcagtg ccaggagaag
     1021 ctcaccaggg tggagaagga gtggcgacgc ttccaggcac tcaagaagca ggtggtgatg
     1081 caggccatgg gcagctgtcg gatgaggggc gggcgccagg ctgctctgcg agaggtggag
     1141 cagatccagg cgttggagga taaaaaggag aaggagatga gcgccgtgcg gctggagaac
     1201 attcagctga agcagagcct ggtgcatttt gaaaccagga tgaggaccca ggaggacctg
     1261 acccagggtc tgcttcttat tgactttgaa cagctgaaga ttgagaacca aaccttcaat
     1321 gagaaaattg aggaacgaaa tgaggaactt ttaaaacttc gcagcaaggt gaccaacagt
     1381 gtgcaagtaa taacccacgt gaaggaaaag ctgcacttca tggacatgga gaacgcgtgc
     1441 aaaaagacac agctggcaga aatcgaggcc caggccgccc taggaagaga catcctgacc
     1501 aagacgaagc aagcccgaga ggggctgcgg acggacaaca tcagactgaa tcagaagtgc
     1561 ggccttctag gcaaggactc acttcttcgg gacttggaag aaaaggtgga caagaccgaa
     1621 ctgcttcacc ggcgcctgga atccctgaag cgccaccacg ctagcctcac tttgtcctgc
     1681 agaggcgtga ggcagaagat cagggaggcc aaagcctttc tcccttcttg accagatcga
     1741 tgagaagagt ctgcaaaaca cttcatcctc aggacgtgct gtcctgcttt attttacctt
     1801 cgttgctatt aaaaaggcct gtgtcatttg ggacgggact ctattttgta tttatctcaa
     1861 aacgttttag cttccaaatc agtgctgagc ccaaacctgg gttaggagtt ttatctggga
     1921 ttgagcaaaa ataggtccag aaaagcaaac aaagggtgat ttaatgtaac tgacttctca
     1981 tgaaaaactg tcaaaagtct caagtctgag caattctata atttcagtga tgtaatacta
     2041 aagagtactg ttcctctttc atatgtagga gggtttaaaa gttcagcgaa tgggcaaggt
     2101 acaaaaaaac cctgtgcatt aagctaatta ttaaattctt tggatttatt aaa
//
