LOCUS       NM_001012502            3704 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens cilia and flagella associated protein 157 (CFAP157),
            transcript variant 1, mRNA.
ACCESSION   NM_001012502 XM_209941
VERSION     NM_001012502.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3704)
  AUTHORS   Hoh,R.A., Stowe,T.R., Turk,E. and Stearns,T.
  TITLE     Transcriptional program of ciliated epithelial cells reveals new
            cilium and centrosome components and links to human disease
  JOURNAL   PLoS One 7 (12), e52166 (2012)
   PUBMED   23300604
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL162426.20.
            
            On Nov 22, 2018 this sequence version replaced NM_001012502.2.
            
            Transcript Variant: This variant (1) represents the protein-coding
            transcript.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2144333 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000373295.7/ ENSP00000362392.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AL162426.20        120301-120304
            5-205               AL162426.20        120305-120505
            206-477             AL162426.20        122735-123006
            478-631             AL162426.20        123914-124067
            632-899             AL162426.20        124542-124809
            900-1030            AL162426.20        125133-125263
            1031-1181           AL162426.20        125512-125662
            1182-1348           AL162426.20        126022-126188
            1349-1535           AL162426.20        126333-126519
            1536-1726           AL162426.20        127147-127337
            1727-3704           AL162426.20        127338-129315
FEATURES             Location/Qualifiers
     source          1..3704
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.11"
     gene            1..3704
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /note="cilia and flagella associated protein 157"
                     /db_xref="GeneID:286207"
                     /db_xref="HGNC:HGNC:27843"
     exon            1..205
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1607
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 157"
                     /protein_id="NP_001012520.2"
                     /db_xref="CCDS:CCDS43878.1"
                     /db_xref="GeneID:286207"
                     /db_xref="HGNC:HGNC:27843"
                     /translation="MAPKKSVSKAGKELEVKKKGGKKEPVVAVEPPLAKEMKEFYHIQ
                     IRDLEDRLARYQRKWDELAVQEKMFRQEFEQLANNKKEIVAFLKRTLNQQVDEITDLN
                     EQLQNLQLAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIILGGKLAALEEFRLQKEE
                     VTDKFTLLEEQVRKQENEFRDYAYNLEKKSVLDKDRLRKEIIQRVNLVANEFHKVTTN
                     RMWETTKRAIKENNGITLQMARVSQQGMKLLQENEQLKGRQNNLCKQLELLENTQKVM
                     ARHKRGHQKIILMLTKKCQEQQQDTKEAEELRLLLSQLEQRSLQLQVDNQALKSQRDQ
                     LSLQLEQQQVDLQRLQQELANEQKVRASLEAALVQATSFLQNILQMHRDEEDSDVDVT
                     FQPWHKEMLQQLLVMLSSTVATRPQKAACPHQESQSHGPPKESRPSIQLPRTGSLLPQ
                     LSDITPYQPGDLGLVPRQVHIPPNPQDLRLLSYITRVGTFRAHSSPEMRAPGSLKRLE
                     KFSLPEVPLRPK"
     exon            206..477
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            478..631
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            632..899
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            900..1030
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1181
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            1182..1348
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1535
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..3704
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1707..1712
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /note="hexamer: TATAAA"
     polyA_site      1725
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
     regulatory      3685..3690
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /note="hexamer: AATAAA"
     polyA_site      3704
                     /gene="CFAP157"
                     /gene_synonym="C9orf117"
                     /note="major polyA site"
ORIGIN      
        1 acctggcctc ttcctggggc ctggagccct ggttgccatc agccatggct cccaaaaaga
       61 gtgtgagcaa ggcaggcaag gagcttgaag tcaagaagaa agggggcaag aaggagccgg
      121 tggtggccgt ggagccgcct ctggccaagg agatgaagga gttctaccac atccagatcc
      181 gagacctgga ggaccggcta gcccggtacc agcggaagtg ggatgagctg gctgtgcagg
      241 agaagatgtt ccgccaggag tttgagcagc tggccaataa caagaaggag attgtggcct
      301 tcctcaagcg cacgctcaac cagcaggtgg atgagatcac agacctcaac gagcagctcc
      361 agaacttgca gctagccaaa gagatggaga aggatgcctt cgaggcgcag ctggcccagg
      421 tgcgccacga gttccaggag accaaggacc agctcaccac ggagaacatc atccttgggg
      481 ggaagctggc agccctggag gagttccggc tgcagaaaga ggaggtcacg gacaagttca
      541 cattgctgga ggagcaggtg cggaagcagg agaatgagtt cagggactat gcatacaacc
      601 tggagaagaa gtcggtgctg gacaaggaca gactgaggaa agagatcatc cagcgcgtga
      661 acctcgtggc caatgagttc cacaaggtga ccacgaaccg gatgtgggag acaaccaagc
      721 gggccatcaa agagaacaac ggcattaccc tgcagatggc cagggtctcc cagcaaggca
      781 tgaagctgct gcaggagaat gagcagctca agggaagaca gaacaatctg tgcaaacagc
      841 tggagctgct ggagaacacc cagaaggtca tggccaggca caaaagaggc caccagaaga
      901 tcatcctcat gctgactaag aagtgccagg agcagcagca ggacaccaag gaggccgagg
      961 agctgcgcct cctgctgagc cagttggagc agagatccct gcagctgcag gtggataacc
     1021 aggcactgaa gagccagaga gaccagctga gcctgcagct ggagcagcag caggtggatt
     1081 tgcagcggct acagcaggaa ctggctaatg agcagaaggt tcgggccagc ctggaggcgg
     1141 ctctggtcca ggccacctcc ttcctacaga acattctgca gatgcaccgc gatgaagagg
     1201 acagtgacgt tgacgtgacg ttccagccat ggcacaagga gatgctgcag caactgctgg
     1261 tcatgctcag ctccactgtg gccacgagac ctcagaaggc tgcgtgtccc caccaggagt
     1321 cacagtccca tggcccaccc aaggagagcc ggcccagcat ccagctgccc aggactgggt
     1381 ctctgctgcc gcagctctct gacatcaccc cctaccagcc gggggatcta ggcctggtac
     1441 ctcgccaggt ccacatccca cccaaccccc aggacctcag gctgctgtca tatatcaccc
     1501 gtgtggggac cttccgggca cacagcagcc ctgagatgcg tgcccctggt tctctaaaaa
     1561 ggcttgaaaa gtttagtctt cctgaagttc ccctacgtcc caagtaggac acagagagaa
     1621 gaacctactc cagaaatgga ctggtccagt cacagtcacc cccactttaa tccgcaggca
     1681 gcctggaaca gtctagagga gatttgtata aaaagtagat accaaggctg gcgtggcagc
     1741 tctgtggcag tggctgggtt ggtgggcact acagtcaggc aggcagccat ggccactagt
     1801 gtcacggccc cagtgagggc ccctggcttc gctcacggat gtggtccaag atcaggtcgg
     1861 tggctcgatc cagcaacaga ggcagcagct cctgctcagc aggggagaag cagcccagca
     1921 catgggcctg aaccgcctca gggtgcgccg ggcgcccgat acccacccgc agccttggca
     1981 ttgcctgtgg gagagccaga gaggcccagg aagctttggc gaggtgctgg gggacccctg
     2041 gcccacccga cccagttgca caacaaaagg gtagactcac attggagttg aggcagctaa
     2101 tgcaggaacg gactccattg tggccccttc aagggatatg ggaggggcag ttagtgcctc
     2161 cctggggcag tgtccttcca cccctccctg ccccggctgg gtcagagcag cccatttcct
     2221 gtggagactg ggtcagcagc cctactccac cccaactggg aggcctgaag ccctatccca
     2281 accctgacca tctcaggacc tcacctggca ctgcccccca gcttcagagc cagtctcccc
     2341 aggggcttgt ccagctcatc atgcaccagg tagacttcct cggcagtcag cccaaacagc
     2401 tccgcttagc acagggaaac ggcagccctg gttactgccc atctgcccag agaggcactg
     2461 tcccgactcc catgatgagg gaccacaact aatcccactt cacatataaa gaaactgagg
     2521 ccccccgaag tacccaaagc catgcagcaa ctggagctca acaggtactt ggaggtgaac
     2581 ccgcggatct gtcacagcca gtgctcccct ctggcccccg cgccccaacc cccaccccct
     2641 tggcccgccc gcccacccct ggcgctctca actcaccagc ccgggccacg ctgcgcccgt
     2701 tggcgttcat aagccgccgt ggccggagca ggaccagttg ggcatccccc agcggggcca
     2761 gggcgaggtc ggcggcacag tgccggtcgc gcgtccaact ctccgccaca cccagccgcc
     2821 gcgccagctg ccccagcacc gccatgccca cgctgtgtcg cgtgccgggc agtccgggat
     2881 tccccaggcc agccacctgc gggcggcacc agggaaactg aggcccaaca actctcgcca
     2941 cccccgatct cacagcgtcc cgtgggcccc aacgcagagg agcggaaacg cagagcaacg
     3001 ctgcagtggg gaaggggcgc gaagaagggg cccagaaacc cgacccctga gaactccaga
     3061 aggctgggca ggcagggcgc cctagtgcag gaacggagct tcaagaagtt tggagcccgt
     3121 cgagcactga actcaccagt taagaaaaca gagcagcaat ttgggggcac tcggctcccg
     3181 ggacataatg gccgaactga agctagggac cgggagcccc tacgtcgccg ccccacgcca
     3241 ctcaccatcc accgcttccc cggggggcga ggctccaaaa cacatcggct catggctcta
     3301 ctcagccgct gtccggcgcc caaaaagccg cccggcctca tgctgccccc attcactccg
     3361 acaccgcccc ctgacgtcat caccccgcag cagccaatcg tgttgccaac tgtttggcgt
     3421 ccaccgccaa cgtccaatcc gggccgggct acgtggccgc catgcttctg aggggcggaa
     3481 gcggcgaggc ggtggccgag tccgggaacc caggcgcctt cagtagcgcg gcgtcacagt
     3541 gtcccttcgg gacttgtgtg ggacgctcgg agctcttgct tgaccttcgg ttgggaggcc
     3601 ttgttatgcc ccccgctatg gccctgactt gcggcgaaaa tctggcaagt cctttccccg
     3661 ctgtaggcct caacctctcc agctaataaa agttttctac ctcc
//
