LOCUS       NM_152290               3564 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens cilia and flagella associated protein 107 (CFAP107),
            transcript variant 1, mRNA.
ACCESSION   NM_152290
VERSION     NM_152290.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3564)
  AUTHORS   Gui,M., Croft,J.T., Zabeo,D., Acharya,V., Kollman,J.M.,
            Burgoyne,T., Hoog,J.L. and Brown,A.
  TITLE     SPACA9 is a lumenal protein of human ciliary singlet and doublet
            microtubules
  JOURNAL   Proc Natl Acad Sci U S A 119 (41), e2207605119 (2022)
   PUBMED   36191189
REFERENCE   2  (bases 1 to 3564)
  AUTHORS   Lahtela,E., Kankainen,M., Sinisalo,J., Selroos,O. and Lokki,M.L.
  TITLE     Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis
            Prognosis
  JOURNAL   Front Immunol 10, 2964 (2019)
   PUBMED   31921204
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY002971.1, BC029894.1 and AC244670.3.
            
            On Nov 22, 2018 this sequence version replaced NM_152290.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK026705.1, SRR5189667.156772.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2145313
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000614859.5/ ENSP00000477802.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                HY002971.1         16-30
            16-1034             BC029894.1         1-1019
            1035-3564           AC244670.3         166402-168931
FEATURES             Location/Qualifiers
     source          1..3564
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..3564
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /note="cilia and flagella associated protein 107"
                     /db_xref="GeneID:93190"
                     /db_xref="HGNC:HGNC:28567"
     exon            1..342
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /inference="alignment:Splign:2.1.0"
     CDS             232..816
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C1orf158; protein CFAP107"
                     /codon_start=1
                     /product="cilia- and flagella-associated protein 107
                     isoform 1"
                     /protein_id="NP_689503.3"
                     /db_xref="CCDS:CCDS147.1"
                     /db_xref="GeneID:93190"
                     /db_xref="HGNC:HGNC:28567"
                     /translation="MFLTAVNPQPLSTPSWQIETKYSTKVLTGNWMEERRKFTRDTDK
                     TPQSIYRKEYIPFPDHRPDQISRWYGKRKVEGLPYKHLITHHQEPPHRYLISTYDDHY
                     NRHGYNPGLPPLRTWNGQKLLWLPEKSDFPLLAPPTNYGLYEQLKQRQLTPKAGLKQS
                     TYTSSYPRPPLCAMSWREHAVPVPPHRLHPLPHF"
     exon            343..456
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /inference="alignment:Splign:2.1.0"
     exon            457..634
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /inference="alignment:Splign:2.1.0"
     exon            635..3564
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1015..1020
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /note="hexamer: ATTAAA"
     polyA_site      1034
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /note="major polyA site"
     regulatory      3542..3547
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
                     /note="hexamer: AATAAA"
     polyA_site      3564
                     /gene="CFAP107"
                     /gene_synonym="C1orf158"
ORIGIN      
        1 agtcaacagt agagaatcca agatagatca actctcccta aaggctgaca gtgaactctt
       61 ggggccgttt tattctctga ggttagcaag gagtcatcta ctagccattc aggaggccag
      121 ctgggaagac aaaataggca ccccaaactc agcaacttca taacaccttc ctctccccgc
      181 ctgaagcctt aaactgcatc aagtcaaaga aacctggggc aaatccttaa catgtttttg
      241 actgcagtaa atccacagcc actctctact ccgagctggc agattgagac caagtattca
      301 acgaaagtgc tcactggaaa ttggatggaa gagaggagaa agttcaccag agacactgac
      361 aagacacccc aatccattta cagaaaagaa tacatcccct tcccagacca cagaccagac
      421 cagatctcca ggtggtatgg gaagaggaaa gttgaggggc taccttacaa acacctgatc
      481 acccaccacc aggagccccc acatcgctac ctgatcagca cctatgacga ccattacaac
      541 cggcatggtt acaacccggg gctgcctcca ctccgcactt ggaatggaca gaagttgctg
      601 tggctgccag agaagtctga ctttcccctt cttgctcccc ctacaaacta tggactctat
      661 gagcagctca agcagagaca gctcacaccc aaggctggcc tgaagcagag cacttatact
      721 tcatcctacc ccagaccacc gttgtgcgct atgtcctgga gggagcatgc ggtcccggtc
      781 cctccccatc gcctgcatcc tctcccacac ttctgagagc tgccacccca ggagcagctc
      841 agatagaatc agctggagac cacagcatca ctggacttgc cagacaacaa gtggcgcaga
      901 taaactcaga gtacgagatc tggcccgtca aaggtgctct cagaatcatc atctgcattt
      961 ggcggtacct gtcccccctc aaaacccaca ggttcctttc ttttccatcc aacaattaaa
     1021 gatctttgac actattgcag ggctatgtac gtgcacaaga cagattcaga ctgtcagaga
     1081 aaacaggaag ggcccttaag ttctaccctg ttgtttcaca agaggggaaa ctgaggcccg
     1141 gagaggtaat gtgacttgct gaagagtcta ctcccatgga ggaaatgaat ctgatgatga
     1201 aacccatcat gaaaactcca cagaatgact gaatgtggtt cccaggaggg cagtgctgca
     1261 gagctggcaa tggggaagga ccccagcttg tctgtcattg ccaaggcaga ggaaggcgtg
     1321 ctctggcccc acggggctca gaagaagggg aaaacacatg gcatttcctt tgtctctgag
     1381 ctcgcaaatc tttgtgtttt tttttttgtt tttttttttg agacggagtg tcgctctctt
     1441 gcccaggctg gagtgccgtg gcacgatctc agctcactgc aacctctgcc tccagggttc
     1501 aagcgattct tttgcctcag cctcctgagt agctgggact acaggtgcgc accactacgc
     1561 ctggctaatt tttgtatttt tagtagagac agggtttcac aatgttggcc aggctggtct
     1621 cgaactcctg acctcgtgat ccgcctgcct cggcctccca aagtgctggg attagcaggc
     1681 gtgagccacc gcacctggct gagctctcaa atctttatga gcctgggcag aggggagaac
     1741 ctctggtgag tgatttggga gagagggtgg atctcctagc agaagaactc aggcatggtc
     1801 ctcgcccagg acaggggtcc acaagtgtgc atgctcagtg ctcgcacaga gctgcctctt
     1861 tgaagaaatt ccagcagaca cctttggccc tttgcatgct tggctcatgg gcacaggtgt
     1921 gttttgtcag tgattttgta ctgcacacca ataatatgac tcccagtatg ggagcctgag
     1981 tctctgccat tgttttcaca ggatacctgc tggcctcagg ccacctacct tagggtcact
     2041 ttggcaccta ctaagttcct tccttagtca tccaagtgtc catgtaagga cgctgtcttc
     2101 catcccaact gaaagtcaga gcctgacaca ggctaagtcc tctatgtttg ttggatgagt
     2161 gaatgacagg agttgaacaa atgagttgaa tgaatgaatg acaggaggag gagccagggg
     2221 gtgcagaaag gttgcaccta ccttagggtc actttggcac ctactaagtt ccttccttag
     2281 tcatccaagt gtccatgtaa ggacgctgtc ttccatccca actgaaagtc agagcctgac
     2341 acaggctaag tcctctatgt ttgttggatg agtggatgac aggagttgaa caaatgagtt
     2401 gaatgaatga atgacaggag gaggagccag ggggtgcaga aaggttgctg caggagacag
     2461 ctgtgggatg gagtggagct ggctgtcctc acacctccaa catccagcct ttctattgag
     2521 catccattga gccatgtctg ggccaggccc tgacctcaca gagcctcagt ccagcagtca
     2581 gggaggagca tgaggtaaat ggctgcagga cagagaggtg ctgcagctgg aggccctggg
     2641 ggacagcgat ggattgcgag gagtgaggga gacccaggat atgctaagca ggggcgtcta
     2701 atcttttggc ttccctgggc tacattggaa gaagaattgt cttgggccac acataaaaaa
     2761 atgaacaggg gctgggcgca gtggctcatg cctgtaattc cagcactttg ggaggcctat
     2821 atgggcggat cacctgaggt caggagtttg tgactagcct gtctagcaca gtgaaacact
     2881 gtctctatta aaaatacaaa aatgagctgg catagtggtt catgcctgga atcccagcta
     2941 ctccagaggc tgaggcagca gaatcgcttg aacccaggag gcggaggttt cagtgagacc
     3001 agatggtacc actgcactcc agccttggtg acagagtgag actccatccc aaaaacaaca
     3061 acaacaacaa caaacttaca ctaacggtag ctgatgagct aaaaaaaaaa tcgcgtaaaa
     3121 aaaccccata atgttttaag taagtttaca aatttatgtt gggccacatt cagcctgcag
     3181 gcggagggtt ggacaagctt gtgcgaaagt aaaggatgtc atgagagcaa cgggcagggg
     3241 ttgacggatg atgaatgaag acctggcctg cctaggtagg gccagggaga atcaggtagg
     3301 tcaaggccag aaagctgagg gagattaccc agctgaaggg acaggttggg agggaagaga
     3361 gggtggcttg ggccatgggg gcaacacgtt tgaagtctct gacttgggaa gaagctgagc
     3421 aaattcctta aaagtccaga aagaccatgc attggtctcc tattgctgct ggaacaaaat
     3481 accacaaact cagtgcccta aagcaacaca tgtttatttg acagttctta ttataaatgt
     3541 gaataaatgc acatttattc agaa
//
