LOCUS       XM_024450235            2517 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens carboxylesterase 4A (CES4A), transcript
            variant X15, mRNA.
ACCESSION   XM_024450235
VERSION     XM_024450235.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024450235.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2517
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..2517
                     /gene="CES4A"
                     /gene_synonym="CES6; CES8"
                     /note="carboxylesterase 4A; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 34
                     ESTs, 109 long SRA reads, and 93% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     23 samples with support for all annotated introns"
                     /db_xref="GeneID:283848"
                     /db_xref="HGNC:HGNC:26741"
     CDS             134..1165
                     /gene="CES4A"
                     /gene_synonym="CES6; CES8"
                     /codon_start=1
                     /product="carboxylesterase 4A isoform X15"
                     /protein_id="XP_024306003.1"
                     /db_xref="GeneID:283848"
                     /db_xref="HGNC:HGNC:26741"
                     /translation="MYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGG
                     AFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRW
                     VQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITS
                     NPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIW
                     SMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYNITKEQVPLVVEEY
                     LDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRETPMMGICPAGHATTRMKSTC
                     SWILPQEWA"
ORIGIN      
        1 agacgctgcc tggattttgc tttgggttcc gtcttctcac tgcggaccct ggattgaaac
       61 gatctccccg cggccgccgc cgctacctgg tgcccgcagg tgcctgcagg agtcctgggg
      121 ccagctggcc tcgatgtacg tcagcacgcg ggaacggtac aagtggctgc gcttcagcga
      181 ggactgtctg tacctgaacg tgtacgcgcc ggcgcgcgcg cccggggatc cccagctgcc
      241 agtgatggtc tggttcccgg gaggcgcctt catcgtgggc gctgcttctt cgtacgaggg
      301 ctctgacttg gccgcccgcg agaaagtggt gctggtgttt ctgcagcaca ggctcggcat
      361 cttcggcttc ctgagcacgg acgacagcca cgcgcgcggg aactgggggc tgctggacca
      421 gatggcggct ctgcgctggg tgcaggagaa catcgcagcc ttcgggggag acccaggaaa
      481 tgtgaccctg ttcggccagt cggcgggggc catgagcatc tcaggactga tgatgtcacc
      541 cctagcctcg ggtctcttcc atcgggccat ttcccagagt ggcaccgcgt tattcagact
      601 tttcatcact agtaacccac tgaaagtggc caagaaggtt gcccacctgg ctggatgcaa
      661 ccacaacagc acacagatcc tggtaaactg cctgagggca ctatcaggga ccaaggtgat
      721 gcgtgtgtcc aacaagatga gattcctcca actgaacttc cagagagacc cggaagagat
      781 tatctggtcc atgagccctg tggtggatgg tgtggtgatc ccagatgacc ctttggtgct
      841 cctgacccag gggaaggttt catctgtgcc ctaccttcta ggtgtcaaca acctggaatt
      901 caattggctc ttgccttata atatcaccaa ggagcaggta ccacttgtgg tggaggagta
      961 cctggacaat gtcaatgagc atgactggaa gatgctacga aaccgtatga tggacatagt
     1021 tcaagatgcc actttcgtgt atgccacact gcagactgct cactaccacc gagaaacccc
     1081 aatgatggga atctgccctg ctggccacgc tacaacaagg atgaaaagta cctgcagctg
     1141 gattttacca caagagtggg catgaagctc aaggagaaga agatggcttt ttggatgagt
     1201 ctgtaccagt ctcaaagacc tgagaagcag aggcaattct aagggtggct atgcaggaag
     1261 gagccaaaga ggggtttgcc cccaccatcc aggccctggg gagactagcc atggacatac
     1321 ctggggacaa gagttctacc caccccagtt tagaactgca ggagctccct gctgcctcca
     1381 ggccaaagct agagcttttg cctgttgtgt gggacctgca ctgccctttc cagcctgaca
     1441 tcccatgatg cccctctact tcactgttga catccagtta ggccaggccc tgtcaacacc
     1501 acactgtgct cagctctcca gcctcaggac aacctctttt tttcccttct tcaaatcctc
     1561 ccacccttca atgtctcctt gtgactcctt cttatgggag gtcgacccag actgccactg
     1621 cccctgtcac tgcacccagc ttggcattta ccatccatcc tgctcaacct tgtgcctgtc
     1681 tgttcacatt ggcctggagg cctagggcag gttgtgacat ggagcaaact tttggtagtt
     1741 tgggatcttc tctcccaccc acacttatct cccccagggc cactccaaag tctatacaca
     1801 ggggtggtct cttcaataaa gaagtgttga ttagacctga atttctccac ctataaaatg
     1861 ggtgtgtgaa gtgaatgatg tctcaatttg agccctgaga gaaaggaagt attgctgcct
     1921 gttccttagt gggctgtgcc tggatgctac actcagtcaa agggtgctac tgcaaagttg
     1981 cctggggtac aaaacacttg ccttttgcct tcatggtctc aagtgcaccc ctcaggacag
     2041 ccacacccca cgctcacttg tccatcagtt taggtcttag tgccacatct agattcctct
     2101 ggcctctcct gcagcccgtg tgtatcccag cctgtcccac agttttgttt cgttgttttg
     2161 tggggttttt tttttttttt ttgagacgga gttttgctct tgtcacccag gctggagtgc
     2221 aatgatgaaa tctcagctca ctgcagcctc agtctcccga gttcaagcga ttctcctgcc
     2281 tcagcctccc aagtagctga gattacagat gcccaccacc atgcccggct tatttttgta
     2341 tttttagtag agatagggtt tcatcatgtc agccaggctg gtctcaaact cctgacctca
     2401 ggtaatccac ccgtctcagc ctgctgaagt gctggaatta caggcatgag ccaccatgcc
     2461 tggccactgt gggctttttg gtggtaaaat acacacgaca aattttacca ttttaac
//
