LOCUS       NM_001379029            3868 bp    mRNA    linear   PRI 16-DEC-2024
DEFINITION  Homo sapiens ceramide transporter 1 (CERT1), transcript variant 7,
            mRNA.
ACCESSION   NM_001379029
VERSION     NM_001379029.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3868)
  AUTHORS   Horibata,Y. and Sugimoto,H.
  TITLE     The ceramide transport protein CERT is involved in
            alkylacylglycerol transfer from the ER to the Golgi for the
            biosynthesis of ether phospholipid
  JOURNAL   Arch Biochem Biophys 752, 109871 (2024)
   PUBMED   38110110
  REMARK    GeneRIF: The ceramide transport protein CERT is involved in
            alkylacylglycerol transfer from the ER to the Golgi for the
            biosynthesis of ether phospholipid.
REFERENCE   2  (bases 1 to 3868)
  AUTHORS   Gehin,C., Lone,M.A., Lee,W., Capolupo,L., Ho,S., Adeyemi,A.M.,
            Gerkes,E.H., Stegmann,A.P., Lopez-Martin,E., Bermejo-Sanchez,E.,
            Martinez-Delgado,B., Zweier,C., Kraus,C., Popp,B., Strehlow,V.,
            Grafe,D., Knerr,I., Jones,E.R., Zamuner,S., Abriata,L.A.,
            Kunnathully,V., Moeller,B.E., Vocat,A., Rommelaere,S.,
            Bocquete,J.P., Ruchti,E., Limoni,G., Van Campenhoudt,M.,
            Bourgeat,S., Henklein,P., Gilissen,C., van Bon,B.W., Pfundt,R.,
            Willemsen,M.H., Schieving,J.H., Leonardi,E., Soli,F., Murgia,A.,
            Guo,H., Zhang,Q., Xia,K., Fagerberg,C.R., Beier,C.P., Larsen,M.J.,
            Valenzuela,I., Fernandez-Alvarez,P., Xiong,S., Smigiel,R.,
            Lopez-Gonzalez,V., Armengol,L., Morleo,M., Selicorni,A.,
            Torella,A., Blyth,M., Cooper,N.S., Wilson,V., Oegema,R.,
            Herenger,Y., Garde,A., Bruel,A.L., Tran Mau-Them,F., Maddocks,A.B.,
            Bain,J.M., Bhat,M.A., Costain,G., Kannu,P., Marwaha,A.,
            Champaigne,N.L., Friez,M.J., Richardson,E.B., Gowda,V.K.,
            Srinivasan,V.M., Gupta,Y., Lim,T.Y., Sanna-Cherchi,S., Lemaitre,B.,
            Yamaji,T., Hanada,K., Burke,J.E., Jaksic,A.M., McCabe,B.D., De Los
            Rios,P., Hornemann,T., D'Angelo,G. and Gennarino,V.A.
  TITLE     CERT1 mutations perturb human development by disrupting
            sphingolipid homeostasis
  JOURNAL   J Clin Invest 133 (10), e165019 (2023)
   PUBMED   36976648
  REMARK    GeneRIF: CERT1 mutations perturb human development by disrupting
            sphingolipid homeostasis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3868)
  AUTHORS   Chung,L.H., Liu,D., Liu,X.T. and Qi,Y.
  TITLE     Ceramide Transfer Protein (CERT): An Overlooked Molecular Player in
            Cancer
  JOURNAL   Int J Mol Sci 22 (24), 13184 (2021)
   PUBMED   34947980
  REMARK    GeneRIF: Ceramide Transfer Protein (CERT): An Overlooked Molecular
            Player in Cancer.
            Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3868)
  AUTHORS   Tamura,N., Sakai,S., Martorell,L., Colome,R., Mizuike,A., Goto,A.,
            Ortigoza-Escobar,J.D. and Hanada,K.
  TITLE     Intellectual-disability-associated mutations in the ceramide
            transport protein gene CERT1 lead to aberrant function and
            subcellular distribution
  JOURNAL   J Biol Chem 297 (5), 101338 (2021)
   PUBMED   34688657
  REMARK    GeneRIF: Intellectual-disability-associated mutations in the
            ceramide transport protein gene CERT1 lead to aberrant function and
            subcellular distribution.
REFERENCE   5  (bases 1 to 3868)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 3868)
  AUTHORS   Kumagai,K., Yasuda,S., Okemoto,K., Nishijima,M., Kobayashi,S. and
            Hanada,K.
  TITLE     CERT mediates intermembrane transfer of various molecular species
            of ceramides
  JOURNAL   J Biol Chem 280 (8), 6488-6495 (2005)
   PUBMED   15596449
  REMARK    GeneRIF: results indicate that CERT can mediate transfer of various
            types of ceramides that naturally exist and their close relatives
REFERENCE   7  (bases 1 to 3868)
  AUTHORS   Hanada,K., Kumagai,K., Yasuda,S., Miura,Y., Kawano,M., Fukasawa,M.
            and Nishijima,M.
  TITLE     Molecular machinery for non-vesicular trafficking of ceramide
  JOURNAL   Nature 426 (6968), 803-809 (2003)
   PUBMED   14685229
  REMARK    GeneRIF: CERT mediates the intracellular trafficking of ceramide in
            a non-vesicular manner
REFERENCE   8  (bases 1 to 3868)
  AUTHORS   Raya,A., Revert-Ros,F., Martinez-Martinez,P., Navarro,S.,
            Rosello,E., Vieites,B., Granero,F., Forteza,J. and Saus,J.
  TITLE     Goodpasture antigen-binding protein, the kinase that phosphorylates
            the goodpasture antigen, is an alternatively spliced variant
            implicated in autoimmune pathogenesis
  JOURNAL   J Biol Chem 275 (51), 40392-40399 (2000)
   PUBMED   11007769
REFERENCE   9  (bases 1 to 3868)
  AUTHORS   Raya,A., Revert,F., Navarro,S. and Saus,J.
  TITLE     Characterization of a novel type of serine/threonine kinase that
            specifically phosphorylates the human goodpasture antigen
  JOURNAL   J Biol Chem 274 (18), 12642-12649 (1999)
   PUBMED   10212244
REFERENCE   10 (bases 1 to 3868)
  AUTHORS   Kalluri,R.
  TITLE     Goodpasture syndrome
  JOURNAL   Kidney Int 55 (3), 1120-1122 (1999)
   PUBMED   10027952
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC116341.2 and AC112183.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a kinase that specifically
            phosphorylates the N-terminal region of the non-collagenous domain
            of the alpha 3 chain of type IV collagen, known as the Goodpasture
            antigen. Goodpasture disease is the result of an autoimmune
            response directed at this antigen. One isoform of this protein is
            also involved in ceramide intracellular transport. Three transcript
            variants encoding different isoforms have been found for this gene.
            [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.860545.1, AF136450.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000643780.2/ ENSP00000495760.1
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-518               AC116341.2         22844-23361         c
            519-653             AC116341.2         17714-17848         c
            654-770             AC112183.3         119180-119296       c
            771-878             AC112183.3         86486-86593         c
            879-1017            AC112183.3         85476-85614         c
            1018-1101           AC112183.3         79456-79539         c
            1102-1259           AC112183.3         76991-77148         c
            1260-1352           AC112183.3         71126-71218         c
            1353-1439           AC112183.3         63087-63173         c
            1440-1532           AC112183.3         60320-60412         c
            1533-1610           AC112183.3         59425-59502         c
            1611-1706           AC112183.3         49707-49802         c
            1707-1839           AC112183.3         46017-46149         c
            1840-1910           AC112183.3         44757-44827         c
            1911-2039           AC112183.3         42064-42192         c
            2040-2169           AC112183.3         41187-41316         c
            2170-3868           AC112183.3         37890-39588         c
FEATURES             Location/Qualifiers
     source          1..3868
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q13.3"
     gene            1..3868
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /note="ceramide transporter 1"
                     /db_xref="GeneID:10087"
                     /db_xref="HGNC:HGNC:2205"
                     /db_xref="MIM:604677"
     exon            1..518
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     CDS             423..2297
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 7;
                     StAR-related lipid transfer (START) domain containing 11;
                     lipid-transfer protein CERTL; collagen type IV alpha 3
                     binding protein; ceramide transfer protein; collagen, type
                     IV, alpha 3 (Goodpasture antigen) binding protein"
                     /codon_start=1
                     /product="ceramide transfer protein isoform 1"
                     /protein_id="NP_001365958.1"
                     /db_xref="CCDS:CCDS4028.1"
                     /db_xref="GeneID:10087"
                     /db_xref="HGNC:HGNC:2205"
                     /db_xref="MIM:604677"
                     /translation="MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRW
                     VVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDP
                     DHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREK
                     LAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLH
                     STNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKR
                     LDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQD
                     KIEEQSQSEKVRLHWPTSLPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHR
                     FSSQVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAV
                     KGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLY
                     LSVIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQ
                     EISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
                     "
     exon            519..653
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            654..770
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            771..878
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1017
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1101
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1259
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1352
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1439
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1532
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1610
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1706
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1839
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..1910
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..2039
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2169
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..3868
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3838..3843
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /note="hexamer: AATAAA"
     regulatory      3842..3847
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /note="hexamer: AATAAA"
     polyA_site      3854
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
     polyA_site      3868
                     /gene="CERT1"
                     /gene_synonym="CERT; CERTL; COL4A3BP; GPBP; MRD34; NEDHSF;
                     STARD11"
                     /note="major polyA site"
ORIGIN      
        1 aaatagtggg ccaggcagga agatggcggc ggtagcggag gtgtgagtgg acgcgggact
       61 cagcggccgg attttctctt cccttctttt cccttttcct tccctatttg aaattggcat
      121 cgagggggct aagttcgggt ggcagcgccg ggcgcaacgc aggggtcacg gcgacggcgg
      181 cggcggctga cggctggaag ggtaggcttc cttcaccgct cgtcctcctt cctcgctccg
      241 ctcggtgtca ggcgcggcgg cggcgcggcg ggcggacttc gtccctcctc ctgctccccc
      301 ccacaccgga gcgggcactc ttcgcttcgc catcccccga cccttcaccc cgaggactgg
      361 gcgcctcctc cggcgcagct gagggagcgg gggccggtct cctgctcggt tgtcgagcct
      421 ccatgtcgga taatcagagc tggaactcgt cgggctcgga ggaggatcca gagacggagt
      481 ctgggccgcc tgtggagcgc tgcggggtcc tcagtaagtg gacaaactac attcatgggt
      541 ggcaggatcg ttgggtagtt ttgaaaaata atgctctgag ttactacaaa tctgaagatg
      601 aaacagagta tggctgcaga ggatccatct gtcttagcaa ggctgtcatc acacctcacg
      661 attttgatga atgtcgattt gatattagtg taaatgatag tgtttggtat cttcgtgctc
      721 aggatccaga tcatagacag caatggatag atgccattga acagcacaag actgaatctg
      781 gatatggatc tgaatccagc ttgcgtcgac atggctcaat ggtgtccctg gtgtctggag
      841 caagtggcta ctctgcaaca tccacctctt cattcaagaa aggccacagt ttacgtgaga
      901 agttggctga aatggaaaca tttagagaca tcttatgtag acaagttgac acgctacaga
      961 agtactttga tgcctgtgct gatgctgtct ctaaggatga acttcaaagg gataaagtgg
     1021 tagaagatga tgaagatgac tttcctacaa cgcgttctga tggtgacttc ttgcatagta
     1081 ccaacggcaa taaagaaaag ttatttccac atgtgacacc aaaaggaatt aatggtatag
     1141 actttaaagg ggaagcgata acttttaaag caactactgc tggaatcctt gcaacacttt
     1201 ctcattgtat tgaactaatg gttaaacgtg aggacagctg gcagaagaga ctggataagg
     1261 aaactgagaa gaaaagaaga acagaggaag catataaaaa tgcaatgaca gaacttaaga
     1321 aaaaatccca ctttggagga ccagattatg aagaaggccc taacagtctg attaatgaag
     1381 aagagttctt tgatgctgtt gaagctgctc ttgacagaca agataaaata gaagaacagt
     1441 cacagagtga aaaggtgaga ttacattggc ctacatcctt gccctctgga gatgcctttt
     1501 cttctgtggg gacacataga tttgtccaaa agccctatag tcgctcttcc tccatgtctt
     1561 ccattgatct agtcagtgcc tctgatgatg ttcacagatt cagctcccag gttgaagaga
     1621 tggtgcagaa ccacatgact tactcattac aggatgtagg cggagatgcc aattggcagt
     1681 tggttgtaga agaaggagaa atgaaggtat acagaagaga agtagaagaa aatgggattg
     1741 ttctggatcc tttaaaagct acccatgcag ttaaaggcgt cacaggacat gaagtctgca
     1801 attatttctg gaatgttgac gttcgcaatg actgggaaac aactatagaa aactttcatg
     1861 tggtggaaac attagctgat aatgcaatca tcatttatca aacacacaag agggtgtggc
     1921 ctgcttctca gcgagacgta ttatatcttt ctgtcattcg aaagatacca gccttgactg
     1981 aaaatgaccc tgaaacttgg atagtttgta atttttctgt ggatcatgac agtgctcctc
     2041 taaacaaccg atgtgtccgt gccaaaataa atgttgctat gatttgtcaa accttggtaa
     2101 gcccaccaga gggaaaccag gaaattagca gggacaacat tctatgcaag attacatatg
     2161 tagctaatgt gaaccctgga ggatgggcac cagcctcagt gttaagggca gtggcaaagc
     2221 gagagtatcc taaatttcta aaacgtttta cttcttacgt ccaagaaaaa actgcaggaa
     2281 agcctatttt gttctagtat taacaggtac tagaagatat gttttatctt tttttaactt
     2341 tatttgacta atatgactgt caatactaaa atttagttgt tgaaagtatt tactatgttt
     2401 tttgatgttc ccctatagag tattgtttcg ttggtttttg ttgttgtcgt tgttgttgtt
     2461 ttaaacaggg tcttgctctg tttcctaagc tgaagtgcaa tgacaccatc acggctcact
     2521 gcaacctcaa cctctggcct caaacaatcc tctcatctca gccttcccag tagctgggag
     2581 tccccacagg catgtgccac catgctcagc taatttttta ttttttgtag agataggggt
     2641 cttgctatgt tacccaagct ggtcttgaac tcctggcctc agacaatcct cctgcctcag
     2701 cctcccaaag tgctgggatt acagacatga gccaccgtgc ctggccttga aaattgtagt
     2761 ttatagcctt taaaacttaa ttcttttatt gtttcctttt tcttctaatg cttatgtaaa
     2821 gaaattttga tattatagaa ctgtagaatt gtagaagtgc aaacttcctg tattctttcc
     2881 tttcccagaa actgttattt ttgttgtata ttcctccaga tttttctgtg tatgtactga
     2941 catatttttg aatgttaaaa tgtttatact tactattata caaaattctt gttttataac
     3001 ctttttttca cttaacaatg tatcttgact atctttcttt ataagacatg agatgtgtaa
     3061 aacatctcat tcttttaaca tctgttacat gcatgttgca gaatttatta actagtccca
     3121 tgttaatgtc tgagttggtt ccatattttt actgtcaacc agtacagcac tgaacacctt
     3181 tatgcaaaga ggtagaatct ttaactttat tttggtgttg ttgagacaaa gtttctctct
     3241 tgctgcccag gctggagtgc agtggtgcaa tcttggctca ctgcaacctc tgcctcccag
     3301 gttcaagcga ttctcctgcc tcagcctccc gagtagctgg gattacaggc gtccatcacc
     3361 acgcccagcc tatttttgta tttttagtag aggcagggtt tcaccatgtt ggccaggctg
     3421 gtctcgaact ccttacctca ggtgacctgc tctcctgggc ctcccaaaat gctgggttta
     3481 caggcgtgag ccactgcact cagcccaaaa tctttaactt tttaaagtaa gtgatacgtt
     3541 aacatgatta aaagccaaaa gtggccaggt gcagtgggtc acacctgtaa tcccaacact
     3601 ttttgggaga ctgaggtggg agaatggctt gaggccagga gttcaagtct agcctggata
     3661 acatagcaag attccatctt gacaaaaaac aattaggcgt ggtggtatac atgtatagtc
     3721 ctaggtactt gggaggctga agcaggaaga tcgctttgtc tgggagtttg aggctgcagt
     3781 gagctgtgat tacacgactg cactccagcc tggacaggta atgtctgtca aaaaataaat
     3841 aaataaagtc aaaagtatga aaaagtta
//
