LOCUS       NM_007186              15434 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens centrosomal protein 250 (CEP250), transcript variant
            1, mRNA.
ACCESSION   NM_007186
VERSION     NM_007186.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 15434)
  AUTHORS   Kim,D.K., Weller,B., Lin,C.W., Sheykhkarimli,D., Knapp,J.J.,
            Dugied,G., Zanzoni,A., Pons,C., Tofaute,M.J., Maseko,S.B.,
            Spirohn,K., Laval,F., Lambourne,L., Kishore,N., Rayhan,A.,
            Sauer,M., Young,V., Halder,H., la Rosa,N.M., Pogoutse,O.,
            Strobel,A., Schwehn,P., Li,R., Rothballer,S.T., Altmann,M.,
            Cassonnet,P., Cote,A.G., Vergara,L.E., Hazelwood,I., Liu,B.B.,
            Nguyen,M., Pandiarajan,R., Dohai,B., Coloma,P.A.R., Poirson,J.,
            Giuliana,P., Willems,L., Taipale,M., Jacob,Y., Hao,T., Hill,D.E.,
            Brun,C., Twizere,J.C., Krappmann,D., Heinig,M., Falter,C., Aloy,P.,
            Demeret,C., Vidal,M., Calderwood,M.A., Roth,F.P. and
            Falter-Braun,P.
  TITLE     A proteome-scale map of the SARS-CoV-2-human contactome
  JOURNAL   Nat Biotechnol 41 (1), 140-149 (2023)
   PUBMED   36217029
REFERENCE   2  (bases 1 to 15434)
  AUTHORS   Mahen,R.
  TITLE     cNap1 bridges centriole contact sites to maintain centrosome
            cohesion
  JOURNAL   PLoS Biol 20 (10), e3001854 (2022)
   PUBMED   36282799
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 15434)
  AUTHORS   Zhou,J., Peng,X., Ru,Y. and Xu,J.
  TITLE     Circ_0060077 Knockdown Alleviates High-Glucose-Induced Cell
            Apoptosis, Oxidative Stress, Inflammation and Fibrosis in HK-2
            Cells via miR-145-5p/VASN Pathway
  JOURNAL   Inflammation 45 (5), 1911-1923 (2022)
   PUBMED   35729462
  REMARK    GeneRIF: Circ_0060077 Knockdown Alleviates High-Glucose-Induced
            Cell Apoptosis, Oxidative Stress, Inflammation and Fibrosis in HK-2
            Cells via miR-145-5p/VASN Pathway.
            Erratum:[Inflammation. 2023 Apr;46(2):780. doi:
            10.1007/s10753-022-01740-y.. PMID: 36112240]
REFERENCE   4  (bases 1 to 15434)
  AUTHORS   Igelman,A.D., Ku,C., da Palma,M.M., Georgiou,M., Schiff,E.R.,
            Lam,B.L., Sankila,E.M., Ahn,J., Pyers,L., Vincent,A., Ferraz
            Sallum,J.M., Zein,W.M., Oh,J.K., Maldonado,R.S., Ryu,J.,
            Tsang,S.H., Gorin,M.B., Webster,A.R., Michaelides,M., Yang,P. and
            Pennesi,M.E.
  TITLE     Expanding the clinical phenotype in patients with disease causing
            variants associated with atypical Usher syndrome
  JOURNAL   Ophthalmic Genet 42 (6), 664-673 (2021)
   PUBMED   34223797
  REMARK    GeneRIF: Expanding the clinical phenotype in patients with disease
            causing variants associated with atypical Usher syndrome.
REFERENCE   5  (bases 1 to 15434)
  AUTHORS   Zeng,L., Fan,X., Wang,X., Deng,H., Zhang,X., Zhang,K., He,S.,
            Li,N., Han,Q. and Liu,Z.
  TITLE     Involvement of NEK2 and its interaction with NDC80 and CEP250 in
            hepatocellular carcinoma
  JOURNAL   BMC Med Genomics 13 (1), 158 (2020)
   PUBMED   33109182
  REMARK    GeneRIF: Involvement of NEK2 and its interaction with NDC80 and
            CEP250 in hepatocellular carcinoma.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 15434)
  AUTHORS   Hirsch,D.S., Pirone,D.M. and Burbelo,P.D.
  TITLE     A new family of Cdc42 effector proteins, CEPs, function in
            fibroblast and epithelial cell shape changes
  JOURNAL   J Biol Chem 276 (2), 875-883 (2001)
   PUBMED   11035016
REFERENCE   7  (bases 1 to 15434)
  AUTHORS   Helps,N.R., Luo,X., Barker,H.M. and Cohen,P.T.
  TITLE     NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase
            localized to centrosomes, is complexed to protein phosphatase 1
  JOURNAL   Biochem J 349 (Pt 2), 509-518 (2000)
   PUBMED   10880350
REFERENCE   8  (bases 1 to 15434)
  AUTHORS   Fry,A.M., Mayor,T., Meraldi,P., Stierhof,Y.D., Tanaka,K. and
            Nigg,E.A.
  TITLE     C-Nap1, a novel centrosomal coiled-coil protein and candidate
            substrate of the cell cycle-regulated protein kinase Nek2
  JOURNAL   J Cell Biol 141 (7), 1563-1574 (1998)
   PUBMED   9647649
REFERENCE   9  (bases 1 to 15434)
  AUTHORS   Mack,G.J., Rees,J., Sandblom,O., Balczon,R., Fritzler,M.J. and
            Rattner,J.B.
  TITLE     Autoantibodies to a group of centrosomal proteins in human
            autoimmune sera reactive with the centrosome
  JOURNAL   Arthritis Rheum 41 (3), 551-558 (1998)
   PUBMED   9506584
REFERENCE   10 (bases 1 to 15434)
  AUTHORS   Golsteyn,R.M., Mundt,K.E., Fry,A.M. and Nigg,E.A.
  TITLE     Cell cycle regulation of the activity and subcellular localization
            of Plk1, a human protein kinase implicated in mitotic spindle
            function
  JOURNAL   J Cell Biol 129 (6), 1617-1628 (1995)
   PUBMED   7790358
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from FO393401.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_007186.5.
            
            Summary: This gene encodes a core centrosomal protein required for
            centriole-centriole cohesion during interphase of the cell cycle.
            The encoded protein dissociates from the centrosomes when parental
            centrioles separate at the beginning of mitosis. The protein
            associates with and is phosphorylated by NIMA-related kinase 2,
            which is also associated with the centrosome. Alternative splicing
            results in multiple transcript variants encoding different
            isoforms. [provided by RefSeq, Dec 2015].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AF049105.1, AF022655.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1968968, SAMEA2142853 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000397527.6/ ENSP00000380661.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               FO393401.1         46098-46251
            155-225             FO393401.1         48804-48874
            226-348             FO393401.1         50483-50605
            349-637             FO393401.1         52765-53053
            638-694             FO393401.1         54075-54131
            695-777             FO393401.1         56243-56325
            778-943             FO393401.1         56539-56704
            944-1050            FO393401.1         57466-57572
            1051-1302           FO393401.1         57804-58055
            1303-1399           FO393401.1         60390-60486
            1400-1501           FO393401.1         62550-62651
            1502-1660           FO393401.1         63173-63331
            1661-1839           FO393401.1         63874-64052
            1840-2022           FO393401.1         64370-64552
            2023-2167           FO393401.1         66002-66146
            2168-2314           FO393401.1         66949-67095
            2315-2545           FO393401.1         68371-68601
            2546-2739           FO393401.1         69731-69924
            2740-2867           FO393401.1         70146-70273
            2868-3037           FO393401.1         70476-70645
            3038-3205           FO393401.1         81137-81304
            3206-3340           FO393401.1         81712-81846
            3341-3484           FO393401.1         83929-84072
            3485-3618           FO393401.1         85024-85157
            3619-3757           FO393401.1         87077-87215
            3758-4106           FO393401.1         88219-88567
            4107-4228           FO393401.1         89095-89216
            4229-4349           FO393401.1         90549-90669
            4350-4471           FO393401.1         92345-92466
            4472-7087           FO393401.1         92890-95505
            7088-7201           FO393401.1         98238-98351
            7202-7357           FO393401.1         98535-98690
            7358-7459           FO393401.1         99443-99544
            7460-7516           FO393401.1         100498-100554
            7517-15434          FO393401.1         101863-109780
FEATURES             Location/Qualifiers
     source          1..15434
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q11.22"
     gene            1..15434
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /note="centrosomal protein 250"
                     /db_xref="GeneID:11190"
                     /db_xref="HGNC:HGNC:1859"
                     /db_xref="MIM:609689"
     exon            1..154
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            155..225
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            226..348
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            349..637
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     CDS             452..7780
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     centrosomal Nek2-associated protein 1;
                     centrosome-associated protein CEP250; 250 kDa centrosomal
                     protein"
                     /codon_start=1
                     /product="centrosome-associated protein CEP250 isoform 1"
                     /protein_id="NP_009117.2"
                     /db_xref="CCDS:CCDS13255.1"
                     /db_xref="GeneID:11190"
                     /db_xref="HGNC:HGNC:1859"
                     /db_xref="MIM:609689"
                     /translation="METRSPGLNNMKPQSLQLVLEEQVLALQQQMAENQAASWRKLKN
                     SQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEATGGPIPQRWENVEEPNLDELLVR
                     LEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQ
                     MEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLT
                     CCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDL
                     EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNA
                     QEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVR
                     SVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQ
                     TVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE
                     EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEV
                     TAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEE
                     ENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADL
                     RDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAA
                     LEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVT
                     QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVN
                     QLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAES
                     ALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ
                     LQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE
                     QEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQD
                     MQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQE
                     AKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELS
                     GGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVL
                     RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHE
                     TMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILE
                     EDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEE
                     VETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPM
                     AVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL
                     VTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQ
                     IHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQ
                     VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEH
                     MKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQ
                     QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADA
                     LQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQE
                     KALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEA
                     ARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLE
                     EALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMI
                     QEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTS
                     PMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL
                     QEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQL
                     GEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERE
                     RRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLT
                     LERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRRLDESLTQSL
                     TSPGPVLLHPSPSTTQAASR"
     exon            638..694
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            695..777
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            778..943
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1050
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1302
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1399
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1501
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1660
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1839
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..2022
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2167
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2314
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2315..2545
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2546..2739
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2740..2867
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2868..3037
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3038..3205
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3340
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3341..3484
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3485..3618
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3619..3757
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3758..4106
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4107..4228
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4229..4349
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4350..4471
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4472..7087
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7088..7201
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7202..7357
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7358..7459
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7460..7516
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7517..15434
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8103..8108
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /note="hexamer: AATAAA"
     polyA_site      8128
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /note="major polyA site"
     regulatory      13663..13668
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /note="hexamer: AATAAA"
     polyA_site      13685
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
     regulatory      15414..15419
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
                     /note="hexamer: AATAAA"
     polyA_site      15434
                     /gene="CEP250"
                     /gene_synonym="C-NAP1; CEP2; CNAP1; CRDHL2"
ORIGIN      
        1 agtcccaccc gccacccgac tctggagctc ccattcttca ggaccctgct gaagtatcgc
       61 ttctcagccg ccttctccag gcgcagctgc attcgcttct cggtttttgc actcgctgtg
      121 caccgagtta ctttcccggc ccctcgttga caccgttcac aggtggctgt tggtctttag
      181 taagggtgct gtcttccctg tctgatcctt agcaaaagta ggaaggtaga gttgttggca
      241 gaaatcctgg gataagagaa tagtttcctg gaagatctgt gcctccaacc agcagagagg
      301 gattgagctt cattgaactc aacagagcca acatttcata gcaccatgtt caagaggagg
      361 ttgaagtggc atggcaatgg ttagagaccc tgctgggcgt gaacaccctc tggctaccta
      421 gggacctgtg ggcctaccac ctggtgccct catggagaca agaagccctg ggttgaacaa
      481 catgaagccc cagtcactgc agctggtact ggaagagcag gtgctggcac tacagcagca
      541 gatggcagag aatcaggcag cctcctggcg gaagctgaag aactcccagg aggcccagca
      601 gagacaagca acccttgtga ggaagctgca ggccaaggtg ctgcagtacc gaagctggtg
      661 ccaagagctg gagaagcggc tagaagccac tggaggacca atcccccaga ggtgggaaaa
      721 tgtggaggag ccaaacctgg atgagctgct ggtccgattg gaggaggagc aacagaggtg
      781 tgagagtcta gcagaggtga acacccagct tcgactgcac atggaaaaag ctgacgtggt
      841 gaataaagcc cttagggaag atgtggaaaa actgacagtg gactggagcc gggcccggga
      901 tgagctaatg aggaaggaga gccagtggca gatggagcag gagttcttca agggctacct
      961 gaaaggggag cacggtcgcc ttctcagtct atggcgggag gttgtgacat tccgacgcca
     1021 cttcctggaa atgaagtcag ctactgacag agatctgatg gagctaaaag ctgagcatgt
     1081 gaggctttca gggtctctgt tgacctgttg tctgcgcttg actgtgggag cacagtctcg
     1141 ggaacccaac ggatctggaa gaatggatgg gcgggagccg gcccagctgc tgctgctact
     1201 agccaagacc caggagctgg agaaggaagc ccatgaaagg agccaggagt taatacagct
     1261 gaagagtcaa ggggatctgg agaaggctga acttcaggac cgggtgaccg agctctctgc
     1321 tctgttgacc cagtctcaga agcaaaatga agattatgaa aagatgataa aggctctgag
     1381 agagacagtg gagatcctgg agacaaatca cacagaatta atggaacatg aagcatctct
     1441 tagtaggaat gcgcaagagg agaagttgtc tttacagcag gtgatcaagg atataaccca
     1501 ggtcatggtg gaagaagggg acaatatagc ccaaggctct ggtcatgaga actctttgga
     1561 attggactct agtatcttct cccagtttga ttaccaggat gcagacaagg ctcttactct
     1621 ggtgcgttca gtgctgactc ggagacgcca ggctgtgcag gacctaaggc agcagcttgc
     1681 aggctgtcaa gaggctgtga acttgttgca acagcagcat gatcagtggg aggaagaggg
     1741 caaagccttg agacagcggc tgcagaagct cactggggag cgggacactc tggcagggca
     1801 gactgtggac ctccagggag aggtggactc tctcagcaag gagcgagagc tgctgcagaa
     1861 ggccagggaa gagctgcggc agcagctgga ggtgctagag caggaggcat ggcgcctgcg
     1921 aagggtaaat gtggagcttc agctgcaggg ggactctgcc cagggccaga aggaggaaca
     1981 gcaggaggag ctgcacctgg ctgtccggga gagggagcgt cttcaggaga tgctgatggg
     2041 cctggaagcc aaacagtcag aatcactcag tgaactgatc actcttcggg aagccctgga
     2101 gtcaagtcac ctggaagggg agttactgag gcaagagcaa acggaagtga ccgcagcgct
     2161 ggctagggca gagcagtcaa ttgcagagct gtcgagttct gaaaacaccc tgaagacaga
     2221 agtagctgat cttcgggctg cagctgtcaa gctcagtgcc ttaaatgagg ctttggcgtt
     2281 agataaagtt gggctgaacc agcagcttct ccagttagag gaggagaacc agtctgtgtg
     2341 cagcagaatg gaggccgcag agcaggcgag aaatgctttg caggtcgacc tggcggaggc
     2401 agagaagagg agggaagccc tgtgggaaaa gaacactcac ctggaggctc agctgcagaa
     2461 agctgaggag gctggggctg agctgcaggc agatctcagg gacatccaag aagagaagga
     2521 agaaattcaa aagaaactaa gtgagtcacg tcaccagcag gaggcagcca cgactcagct
     2581 ggagcagcta catcaggagg caaagcgaca ggaagaagtg cttgccaggg cagtccagga
     2641 gaaggaggcc ctagtacgag agaaagcggc tctagaggtg cggctgcagg ccgtggagcg
     2701 tgaccggcag gacctcgctg aacaactaca ggggctcagc tcagccaagg agctactgga
     2761 gagcagtctg tttgaagccc aacaacaaaa ttctgtgata gaggtcacca aggggcagct
     2821 ggaggtccag attcaaactg tcactcaagc caaggaagta atccaagggg aagtgaggtg
     2881 cctgaagctg gaactggaca ctgaacggag tcaggcagag caggagcggg atgctgcagc
     2941 cagacagctg gcccaggctg agcaagaagg gaagactgcc ttggagcagc agaaggcagc
     3001 ccatgagaaa gaggtgaacc agctccggga gaaatgggag aaggagcgct cctggcacca
     3061 gcaggagctg gcaaaggctc tggagagctt agaaagggaa aaaatggagc tggaaatgag
     3121 gctaaaggag cagcagacag aaatggaggc catccaggcc cagagggaag aagaacggac
     3181 ccaggcagag agtgccctat gccagatgca gctggaaaca gagaaggaga gagtatccct
     3241 cctggagaca ctgctgcaga cgcagaagga gctagcagat gccagccaac aactggaacg
     3301 actgaggcag gacatgaaag tccagaaatt aaaggagcag gagaccactg ggatactaca
     3361 gacccagctc caggaggctc aacgggagct gaaggaggca gcccggcagc acagagatga
     3421 ccttgctgcc ctccaagaag agagcagctc cctgctgcag gataagatgg acctgcagaa
     3481 gcaggtggag gacttgaagt ctcagctggt ggcccaggat gactcccaga ggctggtgga
     3541 gcaggaggtt caggagaagc tgagagagac ccaggagtat aaccgaattc agaaggagct
     3601 ggagagagag aaagccagcc tgactctctc actgatggaa aaggaacaga gactccttgt
     3661 tttacaagaa gctgactcta ttcgacaaca agagctgagt gccctgcgcc aggacatgca
     3721 ggaggcccag ggagaacaga aagagctcag tgctcagatg gaattactaa ggcaagaggt
     3781 gaaggaaaag gaggctgact ttctggccca ggaagcacag ctgctggagg agctggaggc
     3841 gtctcatatc acggagcagc agctgcgagc ctccttgtgg gcccaggaag ccaaggcagc
     3901 ccaactacag ctgcgactgc gcagcacaga gagccagcta gaagcgctgg ccgcagagca
     3961 gcagcccggg aaccaggccc aggcccaggc ccagctggcc agcctctact ctgccctgca
     4021 gcaggccctg gggtctgttt gtgagagcag gcctgagctg agtggtgggg gagactctgc
     4081 tccttccgtc tggggccttg agccagacca gaatggagct aggagcctct ttaagagagg
     4141 gcccctgctg actgctctct ccgctgaggc agtagcatct gccctccaca agcttcatca
     4201 agacctgtgg aagactcaac agacccggga tgttctgagg gatcaggtcc agaaactgga
     4261 agagcgtcta actgatactg aggctgagaa gagccaggtc cacacagagt tgcaggatct
     4321 gcagagacag ctctcccaga atcaggaaga gaaatctaag tgggaaggaa agcagaactc
     4381 cctagaatct gagctgatgg aactacatga aactatggca tccttacaga gtcgcctgcg
     4441 gagagcagag ctacagcgaa tggaagccca gggtgagcga gagttacttc aggcagccaa
     4501 ggagaacctg acagcccagg tggaacacct gcaagcagct gtcgtagaag ccagggctca
     4561 ggcaagtgct gctggcatcc tggaagaaga cctgagaacg gctcgctcag cactgaagct
     4621 gaaaaatgag gaagtagaga gtgagcgtga gagagcccag gctctgcaag agcagggcga
     4681 actgaaggtg gcccaaggga aggctctgca agagaatttg gccctcctga cccagaccct
     4741 agctgaaaga gaagaggagg tggagactct gcggggacaa atccaggaac tggagaagca
     4801 acgggaaatg cagaaggctg ctttggaatt gctgtctctg gacctgaaga agaggaacca
     4861 agaggtagat ctgcagcaag aacagattca ggagctagag aagtgtaggt ctgttttaga
     4921 gcatctgccc atggccgtcc aggagcgaga gcagaagctg actgtgcaga gggagcagat
     4981 cagagagctc gagaaggatc gggagactca gaggaacgtc ttggagcatc agcttctaga
     5041 acttgagaag aaagaccaaa tgattgagtc ccagagagga caggttcagg acctgaaaaa
     5101 gcagttggtt actctggaat gcctggccct ggaactggag gaaaaccatc acaagatgga
     5161 gtgccagcaa aaactgatca aggagctgga gggccagagg gaaacccaga gagtggcttt
     5221 gacccacctt acgctggacc tagaagaaag gagccaggag ctgcaggcac aaagcagcca
     5281 gatccatgac ctggagagcc acagcaccgt tctggcaaga gagctgcagg agagggacca
     5341 ggaggtgaag tctcagcgag aacagatcga ggagctgcag aggcagaaag agcatctgac
     5401 tcaggatctc gagaggagag accaggagct gatgctgcag aaggagagga ttcaggttct
     5461 cgaggatcag aggacccggc agaccaagat cctggaggag gacctggaac agatcaagct
     5521 gtccttgaga gagcgaggcc gggagctgac cactcagagg cagctgatgc aggaacgggc
     5581 agaggaaggg aagggcccaa gtaaagcaca gcgcgggagc ctagagcaca tgaagctgat
     5641 cctgcgtgat aaggagaagg aggtggaatg tcagcaggag catatccatg aactccagga
     5701 gctcaaagac cagctggagc agcagctcca gggcctgcac aggaaggtag gtgagaccag
     5761 cctcctcctg tcccagcgag agcaggaaat agtggtcctg cagcagcaac tgcaggaagc
     5821 cagggaacaa ggggagctga aggagcagtc acttcagagt caactggatg aggcccagag
     5881 agccctagcc cagagggacc aggaactgga ggctctgcag caagaacagc agcaggccca
     5941 gggacaggag gagagggtga aggaaaaggc agacgccctc cagggagctc tggagcaagc
     6001 ccatatgaca ctgaaggagc gtcatggaga gcttcaggac cacaaggaac aggcacgaag
     6061 gctggaggaa gagctggcag tggagggacg gcgggtccag gccctggagg aggtgctggg
     6121 agacctaagg gctgagtctc gggaacagga gaaagctctg ttggccctcc agcagcagtg
     6181 tgctgagcag gcacaggagc atgaggtgga gaccagggcc ctgcaggaca gctggctgca
     6241 ggcccaggca gtgctcaagg aacgggacca ggagctggaa gctctgcggg cagaaagtca
     6301 gtcctcccgg catcaggagg aggctgcccg ggcccgggct gaggctctgc aggaggccct
     6361 tggcaaggct catgctgccc tgcaggggaa agagcagcat ctcctcgagc aggcagaatt
     6421 gagccgcagt ctggaggcca gcactgcaac cctgcaagcc tccctggatg cctgccaggc
     6481 acacagtcgg cagctggagg aggctctgag gatacaagaa ggtgagatcc aggaccagga
     6541 tctccgatac caggaggatg tgcagcagct gcagcaggca cttgcccaga gggatgaaga
     6601 gctgagacat cagcaggaac gggagcagct gctggagaag tctctggccc agagggtcca
     6661 agagaatatg atccaagaga agcagaatct ggggcaagag agagaagagg aggagataag
     6721 gggccttcat cagagtgtaa gggagctaca gctgactcta gcccaaaagg aacaggagat
     6781 tctggagctg agggagaccc agcaaaggaa caacctggaa gccttacccc acagccacaa
     6841 aacctcccca atggaggaac aatctctaaa acttgattct ttagagccca ggctgcagcg
     6901 ggagctggag cggctacagg cagccctgag acagacagaa gccagggaga ttgagtggag
     6961 ggagaaggcc caggacttgg cactctccct agcgcagacc aaggccagtg tcagcagtct
     7021 gcaggaggta gccatgttcc tacaagcctc tgtcctggag cgggactcag aacagcaaag
     7081 gctgcaggat gaactggagc tcaccagacg ggctctggag aaggagcggc tacacagccc
     7141 aggtgcaacc agcacagcag aactggggtc cagaggggag cagggtgtgc agctgggaga
     7201 ggtctcagga gtggaggctg agcctagtcc tgatggaatg gagaagcagt catggagaca
     7261 aaggcttgaa cacctgcagc aagcagtggc ccggctggag attgacagga gcaggctgca
     7321 gcgccacaat gtccagctgc ggagtacctt ggagcaggtg gagcgagaac ggaggaagct
     7381 gaagagggag gccatgcgtg cggcccaggc agggtcccta gagatcagca aggccacggc
     7441 ttcttcaccc acacagcagg atgggagagg acagaagaac tcagatgcca agtgtgtggc
     7501 tgaactgcag aaagaggtgg tcctgctgca agctcagctg actttggagc ggaagcagaa
     7561 gcaggactac atcacccgct cagcacagac cagccgtgag ctagcaggcc tgcaccacag
     7621 cctctcacac tcacttcttg ccgtggccca ggcccctgag gccactgtcc tggaggcaga
     7681 gacccgcagg ctggatgagt ccctgactca aagtctgaca tccccagggc cagtcctgct
     7741 acaccccagc cccagcacta cccaagccgc ctccaggtag cagccacagc caggagcaca
     7801 cagacagaag actgtgtcat gggtcatggc ccctccgcac acctacaggt ttgccaaagg
     7861 aaaagcctgg ctctgttagg cacccaggag ccccaggtcg gcgggtgttc ccaggaagag
     7921 gaagtaaatc tgcaaccctg gggaggaccc caactcacct gggaatgagg caaattgcat
     7981 ttgcttgctc cctatggaat cacccagagg ggtgccttgc cctggctgag ggacatgtac
     8041 tgcctctcat ctagaattta ttttcctagc acttcaccac ctccttcatc ttctccttca
     8101 acaataaacc ctgggatctt tgcattcatt ttctgctgct gtctccactt gtgcagctgg
     8161 gtggcagcac cacatcaagg gagtttatct gggaagaact tgccaaagat tcctgttgag
     8221 gtagcatgca tttattgtac accatgcact gtgataggga agggttacag agaacacaca
     8281 agacaaagcc cctgtccaca gacagcctac agtccagttg atgagaacag gctaacactc
     8341 atttatgagt cagaggcaat tctgtgtact gactagaaga actgtagaaa ttccaggggc
     8401 tgaggaaggg aggcacgaac tggcccttga aagatggagt ggggttggag gtgttgccaa
     8461 gcacacagtg agaagactgg tctgactgtg gcagggggtt ggggctgagc ttgggtgggt
     8521 tgagcgggga gattttggag ggttaaaaga agttctgggg cctcaaaaac acagcgttga
     8581 cctttagcta aagtcagagt ctctgagttc agaagctcca catggcctca ttcctcttct
     8641 actctgggtg aatgtccttg agatgtcgct tcctgggcat atcagctgga actgatctgg
     8701 tcgcctgtag tccaaccatg tgtcaagcca atcagaagga tggactatgg cggaacttct
     8761 cacccatgga ctggtcctag tggaggctgg acagaaccca gctcacaggc ttaagaccta
     8821 ttgctggcaa cctcctcaaa gcctaaaaat tgtttaattt ttttaagaga cagggttttg
     8881 tcctgtcttc caagctggag tgcagtggca caatcacatc ttactgcagc ctgaaactcc
     8941 tgggctcaag tgatcctccc acctcaacct ctcaaagtgc tgggattacc ggtgtgagcc
     9001 accatgccca accagaacag ttttccttaa agaagcaggc cattaccttc ctctggcact
     9061 cccaccataa tctggaattc ctctttacta agcctgggga tggaactgag acctagccaa
     9121 gaatctggga ggggtaagag cagcacccac tcacccagac ctcctaattt ggggctcagc
     9181 cccattatgt ctcattgcac cacacagagt ggaaatgggg ctgttcacag cgactagagc
     9241 tttgttccag aaacctacac atgcagctca gcaacagatg cttagtgaaa acttctgaaa
     9301 ccccagaaac agatctgggg ccccagaaat gctgtcctgg tccctatttc cagtcagatt
     9361 ccctgtagct taaaatcctt acctggcttt taggccattt atttcttttt cctttttttt
     9421 tttttgagac agagttttgc tcttgttgcc caggctggag tgcagtgacg taatctcggc
     9481 tcaccagtgg caacatccac ctcctgggtt caagcaattc tcctgcctcg gcctcctgtg
     9541 tatctgggat tatagacacg tgccaccatg cccggctaat tttgtatttt tagtagagac
     9601 agggtttctc catgttgatc aggctggtct cgaactcccg acctcaggtg atccacccac
     9661 ctcggcctcc caaaatgttg ggattacggg catgagccac cgcgcccggc cctttaggcc
     9721 atttttatgc taggagttgt cagagacaag acttctcttg gttgttcact tgttacatcc
     9781 tccagccctg gttctcaggc tcgggctgac agagggtccc tgttttttac cttagagttt
     9841 cttctcagca tcattttctg taggtcatga gccagggcct taggccccac ataccttctg
     9901 ggcctcagag aggttccagc agctgaaaga catcttagag gctgccaagc agggtcttta
     9961 ttcaggacta gactaatctg tatttgctct tctctttcca tccaaccctc aagagccccc
    10021 cagctccatt atagacctcg gcctagggtc tcccctcccc accagatatt cagagcaggg
    10081 ctggccttca gttcaagtgt agactgtgct cttgccctca cactcgagct tgtggatgat
    10141 cttccactcc ggctttctaa agtacacttt ccttgcccag tagcaggatt gcctctgtgg
    10201 agtgtcccac caataatggt gacaactgct gttttcatca gctccagacc caaagagacc
    10261 tgaagtgggg aagtgtgaag gaaggaatat gtgtcatcca ggggggaccc aactttgcct
    10321 aagggcatga ggccggagcc tcctttcctg accttgtcac atgtggcagg gtataaccag
    10381 aatggtgaat ccagcagacg ggaggagtcc ctggcagtcc agccagttct cgtggatgta
    10441 cttgaggaag gtgcaattgg ccaccagaac atgcaggagt agaggttaga gctcagccac
    10501 agagattatc ttcttgcaga aaactttttt cccccttcct aatcttgtct gctttgatag
    10561 aagctggtac tggctggaaa ggcctgaaag caggagggga caagagtcgt cagaggctgg
    10621 gcaatgttct tgtttccggg gagtgctgag gtccggcggg tgctgcccct gttctctcaa
    10681 ggatcccacg tgctttgtgt gttagagcag tgaccatcac ctcccaaccc aaggaccttt
    10741 gctgctctgc ttcccacatg ggactgccag caccctgaag gcagaaaaac tgaatgtacc
    10801 cgttaaagga ggagaagctg gtggtgtatg ttgagataag gagggtgggg agtgtacagt
    10861 tacaggctgc acagggaggg caagatcaat gttgacacca aagtgccaaa ggctgtctgc
    10921 gccaggtctg gggcccccac tggtcatacc gcctgataaa accattgcag tccacactag
    10981 gtctggaggc ttcgacaccc acagcatgtg ggtgttctca tgcaggccat gagtattcgg
    11041 ggtgctttaa gtgcagggga gttctgttgt ccacgttatt cttaaagccc agaataggcc
    11101 ctgttttatt ctacagagat aggaaggcac tggggctcac agagtggtgc tgcttcccac
    11161 cctcaccctt ctgcccccac ctgagcacag tgtggtgctc agtgatggtt atcctatatt
    11221 ccaaatacgc atggcccagg actggcagag tcggagctcg gggtctagct gtgacctggg
    11281 gatcggttgg agtagcttct tgaccagccg gaattgggtt aggtgtccta gcattggtgc
    11341 ctatggagaa gaacacagac tgtttatcac tcacccctgg ttccagtacc aaggaaaggc
    11401 tggagccatt gcaactggag gcccagcgga ggaagggatc aagaagagga tgcagcccag
    11461 agcccaggac cgagcatcca ccggcctctg gagatggcgt ggtctccagt tgcatcgggg
    11521 cttcagggcc catctgaagt gctgatcaaa ccaggcagac acaccatgct ggtgaaggca
    11581 ggctttgtag atgcggggct gaattgagca gccacagaac ctctgcagct ctggggccag
    11641 tggcagaact tctagaagta cctgtggggt gggaaacccc agccacaaaa gcagtgagct
    11701 gacttccagg cctgaggctt tgcctgcagg cctcatctca gcccatggga cagattcctg
    11761 gtttttttag tttggccttg gggtagatga taccttcagc tgtccaccct gcaatacctc
    11821 acctcctgcc ttctgaccca gtactctgca gagcggggga atggggccag gggacagggg
    11881 cagggaagag gaagaagcaa gagctgccag tgtgctccaa accaagagag ccctccacat
    11941 gattctgggc acagctgagg aggagtgcaa gctcaactct gctcaccaca cttaagaagc
    12001 aggcaaggga ggatgaaggg caaaaacatg gggtcctgag gcccttttac tccctctacc
    12061 ctgctggagg tgaggatgag aggtgagact tcgttggact gtgctcctgg ccagttgatc
    12121 tcacccaact cattacatca gtagcctggt cacagggtgg acactctgac ctcttcttag
    12181 cctttcattg gcaatactac cagctctata tatgccctta tagggcctga accttggctc
    12241 aggtggatgg gcttggaggt aaaataattg aatgggtcag gggtaggagg agagatgagt
    12301 ctctgccaag gctgtgtgat gtgtcatctg agagagtggg taacccctat tcccagcaca
    12361 tggccattta tttagagcca gggaggggga cgagaattca tattcaaatg tgattctttc
    12421 ttaattacta ccagttgttc aggtgaggga atcagggaag gccagattaa taatccacac
    12481 attgcccttg cacctcctgt cttggtttcc tatcaaaacc tctcccgtat ctatgaacat
    12541 tccagccctg caggtcagat tgctggccag gagtagtctc acattctagc tgactgatgg
    12601 cctcggcttc tgctgttgta tgtggtttga tgattcatgc tggagccttt ggctataact
    12661 ctcttccctg tataagggcc atctgaagtt tgtctgcctg actccattac ctggtgaatg
    12721 agattggcta gctgctgctc ctgccccagc tattcagtca tttggcaaat actcatttaa
    12781 acaaagctcc acagggatct ctgagaagga gctcacctct aggcacacag aacctggaca
    12841 cagatgaaag tttgcagaat gacccagttg tgcagaagag acccactggc tgctctcagt
    12901 gaggccaggg agagtcaaac agagcatctt ggacaaagag agggcttgaa ggccctttca
    12961 aagtgtcaag ccagttggat gcacgggttg tgtggagtcc aggggtacat ccagaagcaa
    13021 tggcaggtgt tatccattca ttcaggttag acctctgagc agacggcaga aacgtcagcc
    13081 acaggtgagc ataagctcaa acccccccat tgaaggctac attcttgtcc cacagggcag
    13141 agcacatggc aagtggcatg ctgactcaga caccgggcac tgagaaaagt gggaagccat
    13201 ggtcacagac tctacattcc cctctcctgt tggcctccat cccttcctca accgtccgca
    13261 gaacacctcc ttccagcacc ttagctcctg cctccctctg gacctattca gtcctcaagg
    13321 gtgccctgct aaaggctggg ctgaaagcta agaggagagg tggcattcaa tgtgtcctgt
    13381 gtcctccctg gggttgatta aggggtcgat gcccaataga gtccttcatc ttggtgttca
    13441 gcccagggtc cagctgccaa gggaaggctt ggcaatcaag ggtgatggag ataagaatga
    13501 aaaggggcac caccctgtgc caaagctggc atgttgtata tctgagagag gagctgccta
    13561 ttcacagtgt agggttgtca agctggaggc agggagagaa aagcaagagc tttttggttc
    13621 ctcttgagga tagaatctat aggaaaatgt aagagggtta aaaataaatt tcccatgcat
    13681 ccaaactttt ttctttggta gactttcttg tcatctattt aaaatgaaac aagtgcatgt
    13741 acgtggttaa gacattttag ctaggaatga tggtgcgtgc ctgtagtccc agctacttgg
    13801 gaggctgagg caggaggatc gcttgaacct ggaaggtcaa ggctgcagtg agccgagatc
    13861 ataccactgc actccagcct gagtgataaa agtgagaccc tgtctcaaaa aaaaaaaaaa
    13921 aattaaagaa gttaaacagt gccgggcttg ggggctcacg cctgtaatcc cagcactttg
    13981 ggaggcccag gcaggcagat tgcttgggct caggaattca agaccatcct aagcgaaaaa
    14041 atataaaaat tagctcagtg tgatgatgtg cctgtagtcc cagctactcg ggaggctgag
    14101 gtgggaggat cacctgagcc cagggaggtc aaggttgcag tgaaccatga tcatgtcact
    14161 gcactcactc cagcctgggc aacagagcaa gactgtctca aaaaaaaaaa aaaaggaaat
    14221 taaataaaaa gaagatagca gtttcccacc tcattcttct caaactcctc ttcagaggca
    14281 gcgggttttg tttttttttt aactatgttt ttctactggc tcactttatt cctctaaaat
    14341 agtaacttgt ctatgtggtg ccataacggg tccagtatct ggacacgagg ccgcactacc
    14401 tacacctttg gggattctcg gatcctgact ctgagctacc tcattcctag acacctggtg
    14461 caccacaatg tgtcagggat gtcggtttat gtgggatatt tgcattttgt taggttgtgt
    14521 gtggtagttg agcagccaag ggggtagcat gcggtggata tttgttttag atacacagta
    14581 actggaaact catttactga ggctatttgg ttaccctgaa ctactgtttc taccaaaaag
    14641 gcaggataaa tgctccctca acacacacct ttaattacca attttcagag taaggggttg
    14701 aggtaatagc caccgccagt tttccctttc tctttgagta tcattatgag ctcaaagttt
    14761 tttatatatt cactatgatt caatcatgac agttgctatt tttgatgctc aaattgccgc
    14821 aaatctaatg tccaagtgtt cttgtacttg tctaggccta gaatctttta gtgaagaaaa
    14881 agtatttaga agacaaaaat caggctgagt gcagtggctc acgcctgtaa tcctagcact
    14941 tgtgggaggc tgaggcaggc ggattgcctg agctcaggag ttggagacca gcctgggcaa
    15001 catggtgaaa ccccgtctct actaaaatac aaaaaattag ccgggggtgg cggtgtgcac
    15061 cttgtagtcc cagctactca ggaggctgag gcaggagaat tgcttgaacc caggaggcag
    15121 aggttgcagt gagctgagat cgcgtcactg cactccagcc tgggtggcag agcaagactc
    15181 cgtctcaaaa aaaaaaaaaa tacgaaaaac aaaaaacata atctggattg cagggctgat
    15241 cgttgctaat ggagtgttat ggctgttcag atgacagagg gagaaaatgt actttgtaaa
    15301 ctgttagttc aatgaggtta tgattgcaca acaatgtgaa catacttaat gccactgaac
    15361 tttattgcca ttgataactt ttaaatggta aattttgtgt attattttgt cacaataaaa
    15421 agtttgaaaa tcga
//
