LOCUS       NM_080656               1228 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens CDKN2A interacting protein N-terminal like
            (CDKN2AIPNL), mRNA.
ACCESSION   NM_080656
VERSION     NM_080656.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1228)
  AUTHORS   Kim,M., Park,J., Bouhaddou,M., Kim,K., Rojc,A., Modak,M.,
            Soucheray,M., McGregor,M.J., O'Leary,P., Wolf,D., Stevenson,E.,
            Foo,T.K., Mitchell,D., Herrington,K.A., Munoz,D.P., Tutuncuoglu,B.,
            Chen,K.H., Zheng,F., Kreisberg,J.F., Diolaiti,M.E., Gordan,J.D.,
            Coppe,J.P., Swaney,D.L., Xia,B., van 't Veer,L., Ashworth,A.,
            Ideker,T. and Krogan,N.J.
  TITLE     A protein interaction landscape of breast cancer
  JOURNAL   Science 374 (6563), eabf3066 (2021)
   PUBMED   34591612
REFERENCE   2  (bases 1 to 1228)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 1228)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 1228)
  AUTHORS   Richter,H., Katic,I., Gut,H. and Grosshans,H.
  TITLE     Structural basis and function of XRN2 binding by XTB domains
  JOURNAL   Nat Struct Mol Biol 23 (2), 164-171 (2016)
   PUBMED   26779609
REFERENCE   5  (bases 1 to 1228)
  AUTHORS   Hein,M.Y., Hubner,N.C., Poser,I., Cox,J., Nagaraj,N., Toyoda,Y.,
            Gak,I.A., Weisswange,I., Mansfeld,J., Buchholz,F., Hyman,A.A. and
            Mann,M.
  TITLE     A human interactome in three quantitative dimensions organized by
            stoichiometries and abundances
  JOURNAL   Cell 163 (3), 712-723 (2015)
   PUBMED   26496610
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC008293.1 and BM997508.1.
            
            On Nov 22, 2018 this sequence version replaced NM_080656.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279848.8235.1, SRR1660805.21155.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03267776 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000458198.3/ ENSP00000394183.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1122              BC008293.1         18-1139
            1123-1187           BM997508.1         59-123              c
            1188-1228           BM997508.1         17-57               c
FEATURES             Location/Qualifiers
     source          1..1228
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q31.1"
     gene            1..1228
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /note="CDKN2A interacting protein N-terminal like"
                     /db_xref="GeneID:91368"
                     /db_xref="HGNC:HGNC:30545"
     exon            1..266
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..378
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /note="CDKN2A-interacting protein N-terminal-like protein"
                     /codon_start=1
                     /product="CDKN2AIP N-terminal-like protein"
                     /protein_id="NP_542387.1"
                     /db_xref="CCDS:CCDS4175.1"
                     /db_xref="GeneID:91368"
                     /db_xref="HGNC:HGNC:30545"
                     /translation="MVGGEAAAAVEELVSGVRQAADFAEQFRSYSESEKQWKARMEFI
                     LRHLPDYRDPPDGSGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLP
                     QFTTRSELMKKHQS"
     exon            267..366
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /inference="alignment:Splign:2.1.0"
     exon            367..1228
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1186..1191
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /note="hexamer: AATAAA"
     regulatory      1200..1205
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /note="hexamer: AATAAA"
     polyA_site      1206
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
                     /note="major polyA site"
     polyA_site      1228
                     /gene="CDKN2AIPNL"
                     /gene_synonym="C2AIL"
ORIGIN      
        1 atccggtcct cggctgcggc gggcaccatg gtcggtggcg aggcggctgc cgcagtggag
       61 gagctggttt cgggggtgcg gcaggcggcc gacttcgcgg agcagttccg ctcctactca
      121 gagagcgaga agcaatggaa ggcccgcatg gaattcatcc tgcgccacct gcccgactac
      181 cgcgacccgc ccgacggcag tggccgcctg gaccagctgc tctccctctc catggtctgg
      241 gccaaccatc tcttcctagg ctgcagttac aataaagacc ttttagacaa ggtgatggaa
      301 atggccgatg ggattgaagt ggaagacctg ccacaattta ctaccagaag tgaattaatg
      361 aaaaagcatc aaagctaagc cagaagattt atcacatttt catcatcagc tacaggatta
      421 gaaaggaggc tgggatgaat gtgacataga ccacagcagc tctcttaaga ctcctggtat
      481 taccaacata aagaggcagg tggaatgaga aggactctgt ctagattggc ttttttaaca
      541 ttctcatttt cccaggagtt atcactgtaa aagtatgcat ggatatttat gtatttataa
      601 atcatgcact ctaagatgag ttcatcaaca ttgtaaaagc cctcttttct gttttcaggt
      661 tttttttttt cttatcgaca aggtctcact ctgtcgccca ggcagaagca caaaggtgca
      721 gtattggctc attgcagcct cgaactcctg ggctcatatt ttcagggttt tttgtttttt
      781 gttttgtttt tttgagacag agtcttgctc tgttgcccag gcagtagtgc agtggcgcga
      841 tatattttca gtttttaaac gtcagaattt ttgtttaaaa tgcctttttg ggctgggcac
      901 agtggcttat gcccataata atcccagcac tttgggaggc cgaggtgagc agatcacctg
      961 aggttaggag tttgagacca gcctggccaa cacgatgaaa ccccgtctct actaaaaata
     1021 caaacaaaat tagctgggca tggtggcgga catctgtaat cccagctact caggaggctg
     1081 aagcagaaga actgcttgaa cctgggaggt ggaggttgca gtgagccaag atcgcaccat
     1141 tgcactccat cctgggcgac aaaaatgaaa caccgtctca aaaaaaataa aaataataaa
     1201 ataaaatgcc tttttgttgt tgatgtaa
//
