LOCUS       NM_001330448             946 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens CD164 molecule like 2 (CD164L2), transcript variant 1,
            mRNA.
ACCESSION   NM_001330448 XM_005245868
VERSION     NM_001330448.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 946)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 946)
  AUTHORS   Lu,J., Li,M., Zhang,R., Hu,C., Wang,C., Jiang,F., Yu,W., Qin,W.,
            Tang,S. and Jia,W.
  TITLE     A common genetic variant of FCN3/CD164L2 is associated with
            essential hypertension in a Chinese population
  JOURNAL   Clin Exp Hypertens 34 (5), 377-382 (2012)
   PUBMED   22471352
  REMARK    GeneRIF: Found that a common variant of FCN3/CD164L2 is associated
            with hypertension in Chinese population.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FO393419.1.
            
            On Aug 29, 2016 this sequence version replaced XM_005245868.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968832,
                              SAMEA2144333 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000374030.3/ ENSP00000363142.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-182               FO393419.1         77910-78091
            183-350             FO393419.1         78576-78743
            351-422             FO393419.1         78844-78915
            423-467             FO393419.1         79419-79463
            468-612             FO393419.1         81048-81192
            613-946             FO393419.1         81734-82067
FEATURES             Location/Qualifiers
     source          1..946
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     gene            1..946
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /note="CD164 molecule like 2"
                     /db_xref="GeneID:388611"
                     /db_xref="HGNC:HGNC:32043"
     exon            1..182
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..619
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; CD164 sialomucin-like 2 protein"
                     /codon_start=1
                     /product="CD164 sialomucin-like 2 protein isoform 1
                     precursor"
                     /protein_id="NP_001317377.1"
                     /db_xref="CCDS:CCDS81287.1"
                     /db_xref="GeneID:388611"
                     /db_xref="HGNC:HGNC:32043"
                     /translation="MEAPGPRALRTALCGGCCCLLLCAQLAVAGKGARGFGRGALIRL
                     NIWPAVQGACKQLEVCEHCVEGDGARNLSSCVWEQCRPEEPGHCVAQSEVVKEGCSIY
                     NRSEACPAAHHHPTYEPKTVTTGSPPVPEAHSPGFDGASFIGGVVLVLSLQAVAFFVL
                     HFLKAKDSTYQTLI"
     exon            183..350
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /inference="alignment:Splign:2.1.0"
     exon            351..422
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /inference="alignment:Splign:2.1.0"
     exon            423..467
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /inference="alignment:Splign:2.1.0"
     exon            468..612
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /inference="alignment:Splign:2.1.0"
     exon            613..946
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /inference="alignment:Splign:2.1.0"
     regulatory      925..930
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /note="hexamer: AATAAA"
     polyA_site      946
                     /gene="CD164L2"
                     /gene_synonym="EAPG6122; UNQ6122"
                     /note="major polyA site"
ORIGIN      
        1 acacgctcag ccgagcccag tctgggaggg acgcgcccgg cagctgtcca ccgatcccgg
       61 ccaccgcccc cggccacccc caccccgcga gcccatggag gctccgggac cccgcgcctt
      121 gcggactgcg ctctgtggcg gctgttgctg cctcctccta tgtgcccagc tggctgtggc
      181 tggtaaagga gctcgaggct ttgggagggg agccctgatc cgcctgaata tctggccggc
      241 ggtccaaggg gcctgcaaac agctggaggt ctgtgagcac tgcgtggagg gagacggagc
      301 gcgcaatctc tccagctgcg tgtgggagca gtgccggcca gaggagccag gacactgtgt
      361 ggcccaatct gaggtggtca aggaaggttg ctccatctac aaccgctcag aggcatgtcc
      421 agctgctcac caccacccca cctatgaacc gaagacagtc acaacaggga gccccccagt
      481 ccctgaggcc cacagccctg gatttgacgg ggccagcttt atcggaggtg tcgtgctggt
      541 gttgagccta caggcggtgg ctttctttgt gctgcacttc ctcaaggcca aggacagcac
      601 ctaccagacg ctaatctgac ccctttgggc ctggactcca tcctgagggg aaaggaggat
      661 gcagagggtg gcctctgggc acccttgtgg gtaagcgggg ggcgggggcg ggaaaaactc
      721 tggccgccag tttttggctc ctgcgggcac caagcaggct cagtgtctga tgcctgacat
      781 ctcctcctgt cctgggcctg gaacctgcag ctgagaaaat ccctcaacca cctcgtctcc
      841 tccatcgccc ctgctgggcc ccccagcctg acagtgggtt gtatgcctgc ctctttccac
      901 caactggcct gggcactgcc cccaaataaa ggaactctgc actgca
//
