LOCUS       NM_052848               3329 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 97 (CCDC97), transcript
            variant 1, mRNA.
ACCESSION   NM_052848
VERSION     NM_052848.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3329)
  AUTHORS   Guey,L.T., Garcia-Closas,M., Murta-Nascimento,C., Lloreta,J.,
            Palencia,L., Kogevinas,M., Rothman,N., Vellalta,G., Calle,M.L.,
            Marenne,G., Tardon,A., Carrato,A., Garcia-Closas,R., Serra,C.,
            Silverman,D.T., Chanock,S., Real,F.X. and Malats,N.
  CONSRTM   EPICURO/Spanish Bladder Cancer Study investigators
  TITLE     Genetic susceptibility to distinct bladder cancer subphenotypes
  JOURNAL   Eur Urol 57 (2), 283-292 (2010)
   PUBMED   19692168
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DR001364.1 and BC011577.1.
            
            On Nov 22, 2018 this sequence version replaced NM_052848.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC011577.1, SRR1660803.252946.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000269967.4/ ENSP00000269967.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                DR001364.1         18-34
            18-3329             BC011577.1         1-3312
FEATURES             Location/Qualifiers
     source          1..3329
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..3329
                     /gene="CCDC97"
                     /note="coiled-coil domain containing 97"
                     /db_xref="GeneID:90324"
                     /db_xref="HGNC:HGNC:28289"
     exon            1..185
                     /gene="CCDC97"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..1171
                     /gene="CCDC97"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 97"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 97 isoform
                     1"
                     /protein_id="NP_443080.1"
                     /db_xref="CCDS:CCDS12578.1"
                     /db_xref="GeneID:90324"
                     /db_xref="HGNC:HGNC:28289"
                     /translation="MEAVATATAAKEPDKGCIEPGPGHWGELSRTPVPSKPQDKVEAA
                     EATPVALDSDTSGAENAAVSAMLHAVAASRLPVCSQQQGEPDLTEHEKVAILAQLYHE
                     KPLVFLERFRTGLREEHLACFGHVRGDHRADFYCAEVARQGTARPRTLRTRLRNRRYA
                     ALRELIQGGEYFSDEQMRFRAPLLYEQYIGQYLTQEELSARTPTHQPPKPGSPGRPAC
                     PLSNLLLQSYEERELQQRLLQQQEEEEACLEEEEEEEDSDEEDQRSGKDSEAWVPDSE
                     ERLILREEFTSRMHQRFLDGKDGDFDYSTVDDNPDFDNLDIVARDEEERYFDEEEPED
                     APSPELDGD"
     exon            186..641
                     /gene="CCDC97"
                     /inference="alignment:Splign:2.1.0"
     exon            642..920
                     /gene="CCDC97"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1050
                     /gene="CCDC97"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..3329
                     /gene="CCDC97"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3309..3314
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC97"
                     /note="hexamer: ATTAAA"
     polyA_site      3329
                     /gene="CCDC97"
                     /note="major polyA site"
ORIGIN      
        1 aggcccggaa cttcggtgcc tgggcgcagc ggtgcacccg gacccggaac attctcaggc
       61 gaaagtgtct cttgcgtgcg tgggccggag gttagtgtgc ggggcccgcc gggcggttga
      121 aaagtccgag agaatcagga tggaggccgt ggcgacggcg acggcggcga aggaacccga
      181 taagggctgc atagagcctg gacctgggca ctggggtgag ctgagccgga caccagtccc
      241 atctaaaccc caggacaaag tggaagcagc tgaggcaaca ccagtggccc tggacagtga
      301 cacctccggg gctgaaaatg cagcagtgag tgctatgctg cacgctgtag ccgccagccg
      361 cctgcctgtt tgcagccagc agcagggtga acccgacttg acagagcatg agaaagtggc
      421 catcctggcc cagctgtacc acgagaagcc actggtgttc ctggagcgct tccgcacagg
      481 cctccgtgag gagcatctgg cctgctttgg ccacgtgcgt ggcgaccacc gtgcagactt
      541 ctactgtgct gaggtggccc ggcagggcac tgcccggccc cgcaccctgc gtacccgcct
      601 gcgtaaccgg cgctatgctg ccctgcgaga gctgatccaa gggggcgagt acttcagtga
      661 tgagcagatg cggttccggg cccccctgct atatgagcag tacatcgggc agtatctcac
      721 ccaggaggag ctcagtgccc gcaccccaac ccaccagccc cccaagcccg ggtcccccgg
      781 gagacctgct tgcccgctct ccaacttgct gctccagtcc tacgaggagc gggagctaca
      841 gcagcgtctg ctccaacagc aggaggagga ggaggcctgc ttggaggaag aggaagagga
      901 ggaggacagt gacgaggaag accagaggtc aggcaaggac tcggaggcct gggttcccga
      961 ctcggaggag aggctgatcc tgcgagagga gttcaccagc cgcatgcacc agcgcttcct
     1021 agatggcaag gacggggact ttgactacag cacagtagac gacaaccccg acttcgacaa
     1081 cctcgacatc gtggcacggg atgaggagga gaggtacttt gatgaggaag aacctgagga
     1141 tgcgcccagc ccagagctgg atggggactg atggccgcca cccttcccac cgcctgcccc
     1201 atccccatcc ccaacaaggc agctgattcc aggcctgctc agtgaccctt tctctagggg
     1261 gacatcaggg cagtgcccca caacccacac acaccaccat ctcactgggt ctagtctcat
     1321 ctcagacaac ccccaccccc actgtttctg gggttccctt tctcatctct cccaccctgt
     1381 ctcctgcctc tgtctttctt ggtgtctgtc tgggcttctt tctgtctctt tctgtctttc
     1441 tgtctctctc cctacccccg ctccctcttt ccagtgctct ggctggctgt ctctcccttt
     1501 ctccccctct ctctctgcct taggctctgt ctccaccgca gggcccaagg tgaaagtcct
     1561 ccccttgccg gaggccagct ggcagggcct ttcgtggctg gaagtggcca gtttggttcc
     1621 ggtgctgacc cctaggcccc agcgcagctg cctcccgtgc tgtctgtctc cccctctctg
     1681 tttatgtctg cgctgtgtct cacactcaga gcctccttgc ttctgttagg ttcccatctc
     1741 tccttctgcc tcactctggg cctcttcttt ctacttgtac atttccacct ctctaggcct
     1801 ctgctctcac tgtccctctc tgtctgtctc tcagccttta tctctgggtt ttgatccccc
     1861 actccaggct ctgggcccct tcttccccct tccctcaaac ctggctgcta taggcagcag
     1921 aaccctgacc actgagtaat acagccccag gggagggagg agaccccagg cagggaggat
     1981 gggggcagct ctcttctctc cccaggaccc aggctgtgga tcacggggcc tgccagcttg
     2041 agtgtagagg gaggggggac tctacccttc tcagccccac cagcccccct ctgcccaacc
     2101 acaattttcc cttcctccgc cttcctctcc ctctcctgtt tacactcccc aaatgcgcac
     2161 aggctgttat catgggtcct gagtcatccc acacacagcc tgccccagcg tccctgcccc
     2221 cagctggccg cagggcccgc cccatggagc cccctgccgc cctgggctaa tgggagccag
     2281 atggccgcct ggtgactcag ccaccgggcc tgtgggaacc caggcgtccc gccttcccat
     2341 gcccccacac ccggctcctg ctcccccagc agacacacac aggagggcct ggccactgtt
     2401 gagggggcac acagggcaag ggtcaccaag tcggggccta gggactcctc atgcctctga
     2461 gatggaatgg tggtatcctg ccgtggccaa gcctgaagga ccctcaaaac tgcctcctgg
     2521 agtccacggt tcctgacctc cgagcctcag ctatgccctc tgggtcaacc agaattagag
     2581 ccagacaggg aaagtgagag ctggatggag gcagacaaga tgctcagagc gactattaaa
     2641 gaacgaaagc ctctgctacg gagcgcttct gtcctctgtc aggcccgagc gaagtgcctg
     2701 acaccgggtt ggatcctcag atggccccat gaactagtga agtgggtcaa aggaggcctg
     2761 gaaagatgtt gcttcctcaa ggccactcgg ccatcagagg cagaaatgaa acaggaaccc
     2821 aggcctagaa tcacaaaggt cctagaaacc acttggctgt ctggcctctc aggtgtcagg
     2881 gccatccaga gtgagacagc attggaggga caagtgtgca tgcagatgtc ctcagacggg
     2941 aaggtttgag aagggtcaga tggtaggcgg gcctaacaag ggctccgtgc tagccactgt
     3001 cccgcacaca gacaggatca ggtcatcttg atatggagat cagtccccaa atcactgaat
     3061 tgtcccagca gtgctatgcc ctaggtacta ccaatatcac tcctctattt cccagaggag
     3121 gaagcagcag ctagactcca ggaccttggg gtcatatctc tcagaaagcc aagagtgcag
     3181 gatgagagct gtctgtctct tacctgcctg tatttgtgcc ccatttttaa agagcagagg
     3241 gcctgggcca caggaaaggt atcagccctt ggtgataggc acatttttta ccagtctatc
     3301 atttggtcat taaatttgtt tacaatata
//
