LOCUS       NM_001355573            4643 bp    mRNA    linear   PRI 18-NOV-2023
DEFINITION  Homo sapiens coiled-coil domain containing 92B (CCDC92B),
            transcript variant 1, mRNA.
ACCESSION   NM_001355573
VERSION     NM_001355573.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005696.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001355573.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2154665 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000614400.2/ ENSP00000509343.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               AC005696.1         124736-124977       c
            243-395             AC005696.1         110341-110493       c
            396-443             AC005696.1         105771-105818       c
            444-4643            AC005696.1         96126-100325        c
FEATURES             Location/Qualifiers
     source          1..4643
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p13.3"
     gene            1..4643
                     /gene="CCDC92B"
                     /note="coiled-coil domain containing 92B"
                     /db_xref="GeneID:101928991"
                     /db_xref="HGNC:HGNC:52279"
     exon            1..242
                     /gene="CCDC92B"
                     /inference="alignment:Splign:2.1.0"
     exon            243..395
                     /gene="CCDC92B"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..1033
                     /gene="CCDC92B"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="coiled-coil domain-containing 92B isoform 1"
                     /protein_id="NP_001342502.1"
                     /db_xref="CCDS:CCDS92222.1"
                     /db_xref="GeneID:101928991"
                     /db_xref="HGNC:HGNC:52279"
                     /translation="MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSE
                     LTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALR
                     CSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAPRPGPGA
                     TAEPRPRRRALRARRPPAAHEAAAKGPGRDWAAWDRGAGALDDADPMPDPALFLYARR
                     PLRPSARSPRQPPPQEPPDRAGPQPAPSQPSAPGDPE"
     exon            396..443
                     /gene="CCDC92B"
                     /inference="alignment:Splign:2.1.0"
     exon            444..4643
                     /gene="CCDC92B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4624..4629
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC92B"
                     /note="hexamer: AATAAA"
     polyA_site      4643
                     /gene="CCDC92B"
                     /note="major polyA site"
ORIGIN      
        1 agttccggtc acgttgctgg gtgtttacgc ctcgagcccg cccccgaccc cccttcggcg
       61 cccccgagcc ccccggagcc ccggcccgac tgccccgcag cctcccagca gctgatggcg
      121 ccgcagccgg ggcgggcgct gcagatcccc gggcgcagct agcgtggggg gaagagcgcc
      181 gcccccaccc agcccggccc ggacccaggg ccccgccggc cggtgactcc caggtcccga
      241 aggtggggcc caggcctggg ttgccatgga taccgtgtcc ctggagcatc agatccagag
      301 cgtgcaacgc cacatcagct tcctgaaaaa ggagcagatg gccctgctgc gagacctgca
      361 cctggagatc ctgaggctgc agaaacgctg ctcagaactg acccatgacc tggaaatgag
      421 agaggcccaa tctcaccagc aagaggcggc gtcccgggag ctggagagca agtgccgcgc
      481 gctggagtcg cagctggagg cgcgtgctgc ggccaacgcg gagctgcggc gggaggtggc
      541 gcagcgcgag gcgctggtgt ccgcgctgcg ctgcagcctg cgcaccgagg agcgccgctt
      601 cctggaggag ctgcgccgcc gcagccaccg cgccaccgtg ctgggcaccg agctgcagaa
      661 gcacaccgag gcggccgcct acctctcctg ccagctgcac gcggcgcgcc agagactgca
      721 ggccccgcgc ccgggccccg gcgccaccgc cgagcccagg ccacgccgcc gcgcactgcg
      781 agcccgccgc ccgcctgctg cccacgaggc cgccgccaag ggccccggcc gggactgggc
      841 cgcctgggac cgcggggccg gcgccctcga cgacgccgac cccatgcccg accccgcgct
      901 cttcctctat gcacgcaggc cgctgcggcc cagcgcccgc agcccgcgcc agccgcctcc
      961 ccaggagccc ccggaccgag ccggcccgca gcccgcgccc agccagccca gcgcgcccgg
     1021 ggacccggag taggcgccag gctggccggg gtgacgcggg acggacgggg agggccggcc
     1081 agggacgcag ctcggtcccc gcaggcaggt cccgggtcgg agggcagccg cccctcctcc
     1141 aggaagcggg gcgaggcggc cccggctccc cccaaatccc cgaaccgcca gccttttgta
     1201 cttcccgacg tttccaaagc ttcgagccct ctcctcgcgc gagagttcct ccgcggggcc
     1261 gagcgggggc accttctcta ccgagaggac tcgccgtccc gatcctggcc tggtcccacc
     1321 tgcctgtgag acaggagggg cgggggccac gcccttcccc gggaaagccg acaatccttg
     1381 gtggggtggg gagggctggg ctcgcctacg gaaagggacg cagagtggca ttggcgcccc
     1441 aggccctcta gctccccacc ccccgcctcc cccacccccg cgccgacgcc cttcccgcca
     1501 agccttcttc ctccccagga gaggcccagg ctaggggctg gtccttctac ccccaccctg
     1561 accctgccga taggtccttg caggtgagca cggaacactt tagaagacac gtcctcccag
     1621 agcccctggt gggaaaagtg cgcctgatgg aagcctaact tccatgggcc ctgggagagg
     1681 attacagaac cgcctggttg gccggacttg gtctagagcc gtctccagct cagctcttcc
     1741 cgagtcgcca ccccgctggg tatgcaggga ctgggagctc tgctggggaa gggaggtgac
     1801 aggcctgctg ctggccaggc ttctggaagg caggagctgt cttccttctc aggaggcagc
     1861 cccaggcgtt ttcctggtcc tgtttattgg tgctaatgtt gctcggcttc ctaatcagct
     1921 ggctgcaccc agagacaaga agaagagagc cttggctggg cgcggtggct cactcctgta
     1981 atcccagcac tttgggaggc cgaggtgggc ggatcacctg aggtcaggag ttcgagacca
     2041 gcctggccaa cgtggtgaaa ccccgtctct actaaaaaat acaaaaatta gccgggcgtg
     2101 gtggtgcacg cctgtaatcc cagctactcc ggaggctgag gcaggagaat cgcttgaacc
     2161 tgggaggcag aggttgcagt gagccaagat cgcgccactg cactccagcc tgggcaacaa
     2221 gagcaaaact ccgtctcaaa aacgaaaaaa agaagaaggg cctggcttct tggaagtggc
     2281 agctactgat aggagtttgg gtttgtgttt gctgggggga tggtgggagc acaggttagt
     2341 ccccatcctg gccccctcca cggatgcccc taaacctatc agaatctggc agtggcgggc
     2401 tgctcagttc cctgctgtct agcctgggga atggcgacgt ggaaagggga aagccccacc
     2461 tcctaacgcc ccttctccca agctccccgt ccaccaccaa aggcaggaag gacagtttca
     2521 gcgcagctta ttcccccacc cccagcccag cctagaagga aacacaaacc cctccagccc
     2581 gtgccatccc tcctgtgtgg gtcctgcatc aagtcctaag tgcctgtgag gtcttccagg
     2641 ggcttcgagg ggaggacgtg gggcagggag aggcctttgc ctccctcaca gacacccctt
     2701 tcctgacagg tcctgaccct ggctgaggcc acacattctg tcacgcaggg gtctgggagg
     2761 tgagcagagt caagctctag gggtgacgag ctcttctccc atcacagccc catgaagaag
     2821 ggggagtccc agatcacacc ccctttctct ccatttgttg gagcaggaaa ttggcaagaa
     2881 gtagaaacca gtgagcgagc gcactcaggg ccaagcaatg tgcggctctc ccagctgacg
     2941 ccactcggga ctgcccaaga ccactgagca ataaccacgc ctggtctggg gtgtccagct
     3001 cctgggatgc agatggctga ggttggggca cccttgggac agtgctctcc agtccaactt
     3061 gggccaagaa ggtggcctgg ggtccttgct ctgcctgccc ccacctctac tctctactag
     3121 tcctgtggtt gcgcctgtac catctctgtc ccccctcaag tgtgtgtaac tcactgcacc
     3181 cctattctgt ccccctccct ttcagaacct gtcttgtgtg tgagggcctc actcctctct
     3241 cggaggtgcc cagaggactg tgggaagaag ggcaaagtct ctttccagag gagcgtgcac
     3301 agaccctcat ctcccacgac cacacttttg gggtgaacag ggtgactttg ttaggtcgat
     3361 tcttctgcag agatggtgaa gtactctatc tgcccaccca cccactaaaa gccatagctc
     3421 cgtccgcctg gcctcccccc agctctatag caatagcccc cttccccctt ccctcctggg
     3481 catccagggt gtccagctag gggcccccac cgcactctgg tcccagggat cttccagtgg
     3541 cctgcctgct tctcccgaag tgaccccatc agctccaccc aactcccatc cctcttccag
     3601 caaccacaga taatgacaat tgtttgtgag gtgcttggag atcccctaga tgaaaggttc
     3661 tgggtgctgg ggcagctgac tcactgactc tcagctgagg tgctggaggt gcctgggaaa
     3721 ggaaataagg caagctgggg gagcacctgt agcagataca gggttccagt tttcacagaa
     3781 attcccctcc tcgccctcct ggaaataatg gaaacccctc cacccgcctg cacagaaccc
     3841 tctgtgcagc agaacgagac tgggagctgg agtgcatggc ccgctcttgg ccacaggggc
     3901 ccaactctcc tcagcctcag ggccctggag aggccccacc ctccctgggt ctggcttgag
     3961 agcccacctg gccaaaggga aacctcgcac ccccacgcgc tcctggcccc tggaatatct
     4021 tggtgactaa gaagggaaag gactgcattt ctctctcctc tgctgcacga atccccattg
     4081 ggagagagag tgttgaagag gacactcagg tccctaggcg gagctcctgc cacaccccaa
     4141 gtatggacag ctccaggaca cagagctgca ggtggggacc tccccctgct ctggaaatca
     4201 gccagggagc actgggcagt gcggtttgag gctctgtacc cctggccccc acagctcagc
     4261 cacagcaccc tctagcttgg gggactagtc cagggccaaa atgggataac ccttccccat
     4321 ataagcagta ggatggcgtc ccccctggtg gagagaggaa ggaggcctag agggtgtggg
     4381 gcagcttcga agcgcgggga gccgggggtc tccaagcacc ttctcctgga catgccagcc
     4441 ttgaatgggg gatgtgcagg gcttcaaacc cacctggcag gagccctgtg gcagggcaga
     4501 gggaccctgc tccaaattct ctgttggctg cgcttttgta tccaatgctt ttcagagtgt
     4561 attcactcac ccacagaaat agagccctgt gctttagggg tgactgtcat atgccttatt
     4621 cttaataaaa tctctgaaaa aca
//
