LOCUS       NM_152723               2348 bp    mRNA    linear   PRI 01-AUG-2024
DEFINITION  Homo sapiens coiled-coil domain containing 89 (CCDC89), mRNA.
ACCESSION   NM_152723
VERSION     NM_152723.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2348)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2348)
  AUTHORS   Hassel,S., Eichner,A., Yakymovych,M., Hellman,U., Knaus,P. and
            Souchelnytskyi,S.
  TITLE     Proteins associated with type II bone morphogenetic protein
            receptor (BMPR-II) and identified by two-dimensional gel
            electrophoresis and mass spectrometry
  JOURNAL   Proteomics 4 (5), 1346-1358 (2004)
   PUBMED   15188402
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK095478.1, BI559499.1 and DB509087.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152723.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK095478.1, SRR1660807.169273.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000316398.5/ ENSP00000320649.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AK095478.1         83-83
            2-2                 BI559499.1         40-40
            3-2346              AK095478.1         85-2428
            2347-2348           DB509087.1         399-400
FEATURES             Location/Qualifiers
     source          1..2348
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q14.1"
     gene            1..2348
                     /gene="CCDC89"
                     /note="coiled-coil domain containing 89"
                     /db_xref="GeneID:220388"
                     /db_xref="HGNC:HGNC:26762"
     exon            1..2348
                     /gene="CCDC89"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1190
                     /gene="CCDC89"
                     /note="bc8 orange-interacting protein"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 89"
                     /protein_id="NP_689936.1"
                     /db_xref="CCDS:CCDS8270.1"
                     /db_xref="GeneID:220388"
                     /db_xref="HGNC:HGNC:26762"
                     /translation="MRAPMLQKQQAPRMDTPPPEERLEKQNEKLNNQEEETEFKELDG
                     LREALANLRGLSEEERSEKAMLRSRIEEQSQLICILKRRSDEALERCQILELLNAELE
                     EKMMQEAEKLKAQGEYSRKLEERFMTLAANHELMLRFKDEYKSENIKLREENEKLRLE
                     NSSLFSQALKDEEAKVLQLTVRCEALTGELETLKERCAQDACQAQAREKELLELQSQQ
                     ACTHTKETEQLRSQLQTLKQQHQQAVEQIAKAEETHSSLSQELQARLQTVTREKEELL
                     QLSIERGKVLQNKQAEICQLEEKLEIANEDRKHALERFEQEAVAVDSNLRVRELQRKV
                     DGIQKAYDELRLQSEAFKKHSLDLLSKERELNGKLRHLSP"
     regulatory      1309..1314
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC89"
                     /note="hexamer: AAGAAA"
     polyA_site      1330
                     /gene="CCDC89"
                     /note="major polyA site"
     regulatory      1382..1387
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC89"
                     /note="hexamer: AATACA"
     polyA_site      1401
                     /gene="CCDC89"
                     /note="major polyA site"
     regulatory      2204..2209
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC89"
                     /note="hexamer: TATAAA"
     polyA_site      2233
                     /gene="CCDC89"
     regulatory      2290..2295
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC89"
                     /note="hexamer: AATGAA"
     polyA_site      2310
                     /gene="CCDC89"
     regulatory      2328..2333
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC89"
                     /note="hexamer: AGTAAA"
     polyA_site      2348
                     /gene="CCDC89"
ORIGIN      
        1 gtccctagca acaccctgca gcgtttgaaa tctgagggga aaagactgta gtcagccctt
       61 agtggatgag agcgcctatg ctccagaaac agcaggctcc caggatggac accccgcccc
      121 ctgaagaacg cttagagaag caaaatgaaa aactgaacaa ccaggaagag gagacggagt
      181 ttaaggaact ggacggtctg agggaagcct tggcaaacct ccggggactg tcagaggagg
      241 agaggagcga gaaggctatg cttcgctccc gcattgaaga gcagtcccag ctcatctgca
      301 tcctgaagcg gaggtcagat gaggccctgg agcgctgcca gatcctagag ctgctcaatg
      361 cagagctgga ggagaagatg atgcaggagg ctgagaagct caaggcccag ggtgagtaca
      421 gtcggaaact agaggaacgc tttatgaccc tagcagccaa ccacgagttg atgctccgct
      481 tcaaggatga atacaagagt gagaacatca agctgaggga ggagaatgag aagctgaggc
      541 tggagaatag cagcctcttc agccaggctc tgaaggatga ggaggcgaaa gtattacagc
      601 tcacagtccg gtgtgaggcc ctcactgggg agctagaaac gctgaaggag aggtgtgctc
      661 aggatgcctg ccaggcacag gcgcgcgaga aggagctgct ggagctacag agccagcagg
      721 cctgcaccca caccaaggag acagaacagc tgcgcagcca gctgcagacc ctcaagcagc
      781 agcaccagca ggctgtggag cagatagcta aggcagagga gacacacagc agcctgagcc
      841 aggagctgca ggccaggctg cagaccgtca ctagagagaa agaggagttg ctgcagctgt
      901 ccattgaaag gggcaaagtg cttcagaaca aacaggcaga gatctgccag cttgaggaaa
      961 agttggagat agcaaatgaa gacaggaagc atgcgctgga gcggtttgag caagaggcag
     1021 tggctgtgga cagcaacttg agagtcaggg agcttcagcg caaagtagat gggatccaga
     1081 aggcctacga tgaactcagg ctgcagtctg aagccttcaa aaagcacagc ttggatcttt
     1141 taagcaagga gagagaactc aatggcaaac tccgccatct ctctccatag ggaagtttct
     1201 gcttcctctg gcctgcaatt cagaattcaa atatttgcgt cttagcatta tggcaagagt
     1261 aaagatgata tcccatttat tatactttca agcacaaaag gcaactcaaa gaaaagctac
     1321 tttactatga tattgttgtt attattgtaa agccattatt aattttcatt tctacaccta
     1381 gaatacacaa gatttgccag atttccttct gtgccttaga aatcttaaat ttactagtag
     1441 tatcttctcc tacccataag ttattaattc tcaacctcag atatcttcat ttatgttagg
     1501 attttaaatt agcagcttct atgatttaag tcaatctaag tgcagtgaga tgtgccattg
     1561 tgaaaaataa ttagcacaat tacccactgt agatagttag gcttatagtc tcccatagtt
     1621 gagattgtaa gcaaacatgt atcagcataa tagcatgaat gctttgcaga aaaaaaaaag
     1681 tgtctgactt tattttattt tgcgctagct tggaaaatga ttgagatcaa gttctttaac
     1741 aaagaaggtc aattttattc tgtatgagca atatgattca aataagttat acaaaacaac
     1801 ttttattttt tctgcaagct tagataatat tccatttttt ggttttctct ttaaaaagag
     1861 gatttagatg tgcaataatg caaatatcag tagcttaatt taatattgca cgatatgcta
     1921 atagacaatt agacaatttg gggtaacaaa tcatagcaga cgtgatctat agagtaactc
     1981 agaaattgtt ttgtttctat tagcatattt tttgtaatta agattttcct tttttaaaaa
     2041 aatctaagct gaacgtgtgt atgtatgctt gcagcatttt tgtagtaata cctacatttt
     2101 gtaagaatag ttataaaaac atgatatata tatatgtaaa gttcttaaaa aagttctcaa
     2161 aggtagttat attttcttat cttcctgtaa ttaggtattg atatataaac attattatga
     2221 atacctctca aaatagattg taatgtaata tttttctcac ccattttgct gaaggctacc
     2281 aagttacata atgaatttac ttaaaaaata tgacttggtg cctttttagt aaaaccattt
     2341 ccaagcaa
//
