LOCUS       NM_018219               2888 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 87 (CCDC87), mRNA.
ACCESSION   NM_018219
VERSION     NM_018219.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2888)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2888)
  AUTHORS   Wang,T., Yin,Q., Ma,X., Tong,M.H. and Zhou,Y.
  TITLE     Ccdc87 is critical for sperm function and male fertility
  JOURNAL   Biol Reprod 99 (4), 817-827 (2018)
   PUBMED   29733332
REFERENCE   3  (bases 1 to 2888)
  CONSRTM   Psychiatric GWAS Consortium Bipolar Disorder Working Group
  TITLE     Large-scale genome-wide association analysis of bipolar disorder
            identifies a new susceptibility locus near ODZ4
  JOURNAL   Nat Genet 43 (10), 977-983 (2011)
   PUBMED   21926972
  REMARK    Erratum:[Nat Genet. 2012 Sep;44(9):1072. Fullerton, Janice M
            [added]; Hyoun, Phil L [corrected to Lee, Phil H]; Meng, Fan Guo
            [corrected to Meng, Fan]]
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK001648.1, AP001157.4 and AI391530.1.
            
            On Nov 23, 2018 this sequence version replaced NM_018219.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK001648.1, BC034469.2 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000333861.5/ ENSP00000328487.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2260              AK001648.1         1-2260
            2261-2561           AP001157.4         9607-9907           c
            2562-2888           AI391530.1         8-334               c
FEATURES             Location/Qualifiers
     source          1..2888
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.2"
     gene            1..2888
                     /gene="CCDC87"
                     /note="coiled-coil domain containing 87"
                     /db_xref="GeneID:55231"
                     /db_xref="HGNC:HGNC:25579"
     exon            1..2888
                     /gene="CCDC87"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..2598
                     /gene="CCDC87"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 87"
                     /protein_id="NP_060689.2"
                     /db_xref="CCDS:CCDS8145.1"
                     /db_xref="GeneID:55231"
                     /db_xref="HGNC:HGNC:25579"
                     /translation="MMEPPKPEPELQRFYHRLLRPLSLFPTRTTSPEPQKRPPQEGRI
                     LQSFPLAKLTVASLCSQVAKLLAGSGIAAGVPPEARLRLIKVILDELKCSWREPPAEL
                     SLSHKNNQKLRKRLEAYVLLSSEQLFLRYLHLLVTMSTPRGVFTESATLTRLAASLAR
                     DCTLFLTSPNVYRGLLADFQALLRAEQASGDVDKLHPVCPAGTFKLCPIPWPHSTGFA
                     QVQCSNLNLNYLIQLSRPPEFLNEPGRMDPVKELKSIPRLKRKKPFHWLPSIGKKREI
                     DISSSQMVSLPSYPVAPTSRASPSPFCPELRRGQSMPSLREGWRLADELGLPPLPSRP
                     LTPLVLATESKPELTGLIVAEDLKQLIKKMKLEGTRYPPLDSGLPPLLGVVTRHPAAG
                     HRLEELEKMLRNLQEEEASGQWDPQPPKSFPLHPQPVTITLKLRNEVVVQAAAVRVSD
                     RNFLDSFHIEGAGALYNHLAGELDPKAIEKMDIDNFVGSTTREVYKELMSHVSSDHLH
                     FDQGPLVEPAADKDWSTFLSSAFLRQEKQPQIINPELVGLYSQRANTLQSNTKKMPSL
                     PSLQATKSWEKWSNKASLMNSWKTTLSVDDYFKYLTNHETDFLHVIFQMHEEEVPVEI
                     VAPARESLEIQHPPPLLEDEEPDFVPGEWDWNTVLEHRLGAGKTPHLGEPHKILSLQK
                     HLEQLWSVLEVPDKDQVDMTIKYSSKARLRQLPSLVNAWERALKPIQLREALLARLEW
                     FEGQASNPNRFFKKTNLSSSHFLEENQVRSHLHRKLNLMESSLVSLLEEIELIFGEPV
                     IFKGRPYLDKMKSDKVEMLYWLQQQRRVRHLVSALKDPHQSTLFRSSAASL"
     regulatory      2861..2866
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC87"
                     /note="hexamer: AATACA"
     polyA_site      2888
                     /gene="CCDC87"
                     /note="major polyA site"
ORIGIN      
        1 agtaacccct cggctttctg ttcctggacg gtggcggccg ccggctctat gatggagccc
       61 ccgaagcccg agcctgagct ccagcggttt taccaccggc tgctgcgtcc gctgtcgctc
      121 ttccccacta ggacgacgtc cccagagcct cagaagcgcc ccccgcagga gggccggatt
      181 ctgcagtcct tccctctggc gaagctgacg gtggcgtcgc tgtgcagcca ggtggccaag
      241 ctgctggccg gcagcgggat agcagcggga gtgcctcctg aggcccgact acgtctcatc
      301 aaggtcatcc tggacgagct gaagtgcagc tggcgggagc cgcccgccga acttagtctg
      361 agccacaaaa acaaccagaa gctgcggaag cggctcgagg cctacgtgct gctgagcagc
      421 gagcagctct tcttgcgcta cctgcacctg ctggtgacca tgtcgactcc caggggggtc
      481 ttcactgaat cagccaccct cacccggttg gccgccagcc tcgccaggga ctgcacactc
      541 ttccttacta gtcccaacgt ctaccgtggc ctgcttgccg acttccaggc cctgctgagg
      601 gcagagcagg cctctgggga tgtggacaag ctgcaccctg tctgccccgc tgggacgttc
      661 aagctgtgcc ctatcccctg gcctcacagc actggcttcg cccaagtgca gtgctctaac
      721 ctcaacctga actacctcat ccaactcagc cgtccaccag agtttctcaa tgagccagga
      781 aggatggatc cagtgaagga attgaagtcc atccctcggt tgaagaggaa aaagcctttc
      841 cactggctgc cctccatagg aaagaagaga gaaatcgaca tcagttcctc acagatggtg
      901 tcgctgccca gctatcctgt ggcccccacc agcagggctt ccccctcgcc tttctgccct
      961 gagctccgga gaggccaatc catgccctcc ctgcgtgagg gctggaggct ggcagatgag
     1021 ttgggccttc ctccactccc atctcgcccc ttaaccccgc tggtcttggc tacagagagc
     1081 aaaccagagc tgactgggct catcgtggct gaggatctga agcagttgat aaagaagatg
     1141 aagttggagg ggactcgcta cccaccactg gactcaggcc tgcctcctct cctgggggtt
     1201 gtgacccgtc acccagctgc agggcatcgc ctggaggagc tggagaagat gttgaggaac
     1261 ctccaggagg aagaagcctc tgggcagtgg gacccccagc cccccaaatc ctttccactt
     1321 cacccacagc cagtgaccat tactttgaag cttagaaatg aggtcgtggt ccaggcggct
     1381 gccgtacggg tctctgatag aaacttctta gactctttcc acattgaggg ggccggagcc
     1441 ctgtataacc atctggctgg tgaactggat cccaaagcca ttgaaaaaat ggatattgat
     1501 aactttgttg gcagtactac cagggaggtc tacaaggagt tgatgagcca tgtctcttct
     1561 gaccacttac attttgatca agggccccta gttgagcctg cagcagataa agactggtcg
     1621 accttcctgt cctcagcctt tctacgtcaa gaaaaacagc ctcaaatcat caaccctgag
     1681 ctggttggac tttactccca gagagcaaac actttacagt ccaatactaa gaagatgccc
     1741 tccctcccat cactccaagc taccaaaagc tgggagaagt ggtcaaacaa ggcctccttg
     1801 atgaactcat ggaaaaccac cttgtctgtg gatgactact tcaagtacct caccaaccat
     1861 gaaacagatt tccttcatgt catctttcaa atgcatgaag aagaggttcc tgtggagatt
     1921 gtggcccctg ccagagagtc cctagagatt cagcaccctc ccccattgct agaagatgaa
     1981 gaaccagact ttgtgccagg agagtgggat tggaacactg tgctagagca caggctagga
     2041 gctgggaaga caccccacct gggagaaccc cacaaaattc tgagcctgca gaagcatctg
     2101 gaacaactgt ggtctgtgct tgaggtccct gacaaggacc aggtggacat gaccattaaa
     2161 tatagctcca aagcccgcct gaggcagctg ccttcattgg tgaatgcctg ggagcgggcc
     2221 ctgaagccca ttcagctgcg ggaggcattg ctggcgagac tagagtggtt tgagggacaa
     2281 gcttccaatc ccaaccgctt cttcaaaaag accaacttga gctccagtca cttcctggag
     2341 gagaatcagg tccgaagcca tctccacagg aagctcaact taatggagtc ttctttggtt
     2401 tccctcctgg aggagataga gttaatcttt ggcgagccag tgatcttcaa ggggcggccc
     2461 tacctggaca agatgaagag tgacaaagtg gagatgctct attggctgca acagcagcgg
     2521 cgggttcgcc acctggtctc ggccctgaag gatccccacc agtcaaccct gttcaggagc
     2581 tcagcagcca gcctttagta gctcctggga atacccctat tactccttga ccaggcccag
     2641 tgccctcaaa tgcctccctc acccctaaat ggccagcagc tcatctagac ctctttactg
     2701 ctttggaaga agaaatattt gtctatatct gggagtggag ggttcaggaa cattatgctt
     2761 ccaactatga agggattgag actaaaacta ttgttttctt agtgaaattc tcatgaaaga
     2821 atccccaagc ctagtagtcc cattatgtca agccttgcac aatacaagcc aaatctccta
     2881 tatcaaaa
//
