LOCUS       NM_175884               6799 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 71 like (CCDC71L), mRNA.
ACCESSION   NM_175884
VERSION     NM_175884.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6799)
  AUTHORS   Bis,J.C., White,C.C., Franceschini,N., Brody,J., Zhang,X.,
            Muzny,D., Santibanez,J., Gibbs,R., Liu,X., Lin,H., Boerwinkle,E.,
            Psaty,B.M., North,K.E., Cupples,L.A. and O'Donnell,C.J.
  CONSRTM   CHARGE Subclinical Atherosclerosis Working Group
  TITLE     Sequencing of 2 subclinical atherosclerosis candidate regions in
            3669 individuals: Cohorts for Heart and Aging Research in Genomic
            Epidemiology (CHARGE) Consortium Targeted Sequencing Study
  JOURNAL   Circ Cardiovasc Genet 7 (3), 359-364 (2014)
   PUBMED   24951662
REFERENCE   2  (bases 1 to 6799)
  AUTHORS   Sharon,D., Tilgner,H., Grubert,F. and Snyder,M.
  TITLE     A single-molecule long-read survey of the human transcriptome
  JOURNAL   Nat Biotechnol 31 (11), 1009-1014 (2013)
   PUBMED   24108091
REFERENCE   3  (bases 1 to 6799)
  AUTHORS   Wistow,G., Bernstein,S.L., Wyatt,M.K., Fariss,R.N., Behal,A.,
            Touchman,J.W., Bouffard,G., Smith,D. and Peterson,K.
  TITLE     Expressed sequence tag analysis of human RPE/choroid for the
            NEIBank Project: over 6000 non-redundant transcripts, novel genes
            and splice variants
  JOURNAL   Mol Vis 8, 205-220 (2002)
   PUBMED   12107410
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB482357.1, BM068758.1, AK093350.1, AC004917.2 and AI674055.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 2, 2019 this sequence version replaced NM_175884.5.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1163655.368948.1, AK093350.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000523505.3/ ENSP00000430897.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               DB482357.1         32-147
            117-552             BM068758.1         88-523
            553-1797            AK093350.1         279-1523
            1798-4029           AC004917.2         21199-23430         c
            4030-4394           AI674055.1         3-367               c
            4395-6799           AC004917.2         18429-20833         c
FEATURES             Location/Qualifiers
     source          1..6799
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.3"
     gene            1..6799
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /note="coiled-coil domain containing 71 like"
                     /db_xref="GeneID:168455"
                     /db_xref="HGNC:HGNC:26685"
     exon            1..6799
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /inference="alignment:Splign:2.1.0"
     CDS             263..970
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 71L"
                     /protein_id="NP_787080.2"
                     /db_xref="CCDS:CCDS55151.1"
                     /db_xref="GeneID:168455"
                     /db_xref="HGNC:HGNC:26685"
                     /translation="MRRSMKRRRRRRPVAPATAARGGDFRAEDGAGLEAREEKVVYSR
                     SQLSLADSTKALGDAFKLFMPRSTEFMSSDAELWSFLCSLKHQFSPHILRSKDVYGYS
                     SCRALVPDPPGPPTARGQARRPVPRAAARRRRRGARAAAARRRKPRPPPPPPPPPEES
                     CPAKPVAPGPCFGGRTLEEIWRAATPTLTTFPTIRVGSDVWGERSLAAARRRARQVLR
                     VNLEPMVRLRRFPVPRA"
     regulatory      1776..1781
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /note="hexamer: AATAAA"
     polyA_site      1798
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /note="major polyA site"
     regulatory      4373..4378
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /note="hexamer: AATAAA"
     polyA_site      4392
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
     regulatory      6773..6778
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
                     /note="hexamer: AATAAA"
     polyA_site      6799
                     /gene="CCDC71L"
                     /gene_synonym="C7orf74"
ORIGIN      
        1 aagagaggag aagaaagaga aaccaggggg gcgaggcgcc gtccaatgac aaagcccagg
       61 ggtgggcgcc ggccgccatc ttgtaccggg cagcaggata ttcgcccgcg tcctccgccc
      121 tcggaggggg aggggcggcg gcggaggcga gaaaagtagc gagagacgcc agcagcagcc
      181 gccgccgcgg agccaacgcg gactgggacg gcggcggcag tagtgggacc cggcgagcgt
      241 gagtggcccg gagcggcctt cgatgcggcg cagtatgaag aggcggcggc gccggcgccc
      301 ggtcgccccg gccacggccg cccggggcgg cgactttagg gcagaagacg gggctgggtt
      361 ggaggcgcgg gaggagaagg tggtgtactc gcggtcgcaa ctgtcgctgg ctgacagcac
      421 caaggcgctg ggcgacgcct tcaagctctt catgccccgc agcacggagt tcatgagctc
      481 ggacgcggag ctctggagct tcctctgcag cctcaagcac cagttctccc cgcacatcct
      541 gcgcagcaag gacgtctacg gctactcctc ctgccgggcc ctggtacccg accccccggg
      601 gccccctaca gcccgcggcc aggcgcgccg gccggttccg cgcgcagcgg ccaggaggag
      661 gcgccgcgga gcccgggcgg ccgctgcccg caggaggaag ccccggccgc cacccccacc
      721 gccgccgccc cccgaggaga gctgcccggc caagcccgtg gcccccgggc cctgcttcgg
      781 gggccgcacc ttggaggaga tctggagggc ggccaccccg acgctgacca ccttccccac
      841 catccgcgtc ggcagcgacg tgtggggcga gcgcagcctg gcggcagcgc ggcgcagggc
      901 gcgccaggtc ctgcgagtga acctggaacc catggtgagg ctccgccgct tcccggtgcc
      961 ccgggcatga ggtgcggcct ccagggcgcc tcctgccggc cccgaccttg ggacaggcct
     1021 tccgcccgga ggaatgaaca agtgtcagtc gagtgtttac agatccggcc aggaccccgg
     1081 cccccaatgc actttacgcg cgaagaagtt gccggatggt tgtccctgtc ccgggccgcg
     1141 gcgcggtcgt cttggacgct ggggcaggtg tgccctctgc tgcctcccgt acccggcctg
     1201 cggagggagg ggacagctgg acccgcaggg gaggtccctt tcttcctgac caccgattga
     1261 gacgtctcca ggaccttagg ggcagatccg ttttctcact gttggactct acctcactgg
     1321 tctggaagtc ctccgaagac attatttttc caaaggaatt tggtttcgtg cttgtgtaat
     1381 aaagccagaa tttacttgtt ctttatctcc ccctttttct atttcactgt cacccctctt
     1441 tgtggacaga agttcgaaca tgtggtgttg cactagtttg tgctcagggt attctgaagc
     1501 ccactcgttt cctaattttt actggattcc aaagctttga tcgaggatat tttttaagag
     1561 gttcaagctt gtgactgtta gtagtgcaag gatttgtatg ggctcagtga ttacaaacaa
     1621 agacatgcaa aatacaactg tttaaacatt ttcaaggtat ttttaaaggt tttgtattga
     1681 aacaatgttt atatttactg agctcctaaa aatggtagaa tacacatgaa aacttttgtt
     1741 taggaaaagt taacttgtta aattcttttg aattgaataa aaaaatgcat tgaaaccata
     1801 tggtgtgtga ttaaaaaaaa tgaataaatt gtgaagaact ggttttggtt acaggagtca
     1861 ctggaatccg actggagatg atttggcccc ctgtcctggt ctaacataca aatctaggaa
     1921 tattatgcgt taaagtattt taaaatacat tatccttgta atgtatttta caaggataat
     1981 gtattttaaa atgggagttg cataggagag atggatgtgt gtaaacatta tcactaaaat
     2041 gataaacaga atacccatta gaattcttag aactattaat gatcaagagg ggtggaggca
     2101 tttcttggta tcaaataact ggttaaggtt actttgggcg aaatctattt cctttttgtt
     2161 tttgttgttg gataacaaga aatgtctaga ctaatattca tcagttttac aaacataatg
     2221 aaaattagtt gatttttagt tgattttttt gtcccaacat tttttttaac ctttttgcca
     2281 ctcattatat gtttgcagtt ctaggtcttt gacagctgaa gaccacagga atcaaacagg
     2341 cgagacacac agaatactga cccttcttta cgcttttata gtgtttatac catatggccc
     2401 agtgtggaat tcttgattat ccaagtgcct ttggtcattt gtggcaggaa aacttaatag
     2461 tttttagcca gcagtgccac agccagcttt tactgcaata cctaaagggt caagtagtgt
     2521 ttttgtacca ctattatttc aaatttaagt attctgccat gaaacgatcc atactgggct
     2581 ggaacttgac atgtgaaatc tttaatacta aagcttatct ctgcttggca gctttttagg
     2641 agaataatga gagttacaat tttgactctt gcgttcctag aattcaaatg gcatagcttt
     2701 ctgaaatgag tatttcaagt ttagtagtcc gtataggagt gttgtgactt caatttcagt
     2761 gttcttgtta aaagaaataa tatgatatat atatacacac atatatataa cttgatgcca
     2821 gttttctagt aagcctcagt cttttattca ctactcaatg ataatgcatt gtacaaacac
     2881 tgtcacatga gtaaataaaa atgaataatt ccttagaaga tggagagtgt taaattatat
     2941 ttgtgatagg aagcttagac atatcttttg gttattagct tccattgcca attgtatttc
     3001 agatgcatag ggttttcttc ccaaaaatat attgttaact tttatagcta actagcacct
     3061 ggaaaaaatg tatttgtaca actttactat tgtatatagt tttataataa tgaaaaataa
     3121 acccaatggc catattagaa tgcaatttcg acatacagct tatctagata gttttccaga
     3181 ggattttgaa atttggctta actgggagga taactgctca gcacaccact gaaacataac
     3241 cactgacacc attcatttat tttaactgag attcttgaca tttttctctc ctatgccttg
     3301 ttactttagc atacttgaac tcacataaat gcttctttgg attacatggg ctatctgatt
     3361 ccattttgga tctgattgtc catcttgaat tcaatatggt attcatctgg actattcaaa
     3421 aattatgcca tttctagtct gtgaaataag atgtaaaaaa tctttatttt tgccctttgg
     3481 taaaaaccta tgtgacaact tttaaaatgt gaagcaacat ctaatatagt tgactggtat
     3541 actaatagga aagtgaaagt atttcatggg tactttgtca cagaatgtga aaagaaactt
     3601 ggcatagtgg cctttataat gaggcatcca cttactcctc tgaagtgaag tctgtagctt
     3661 agcttgtgta tagtttttga aagaaatctc atgatcttcg ttcattctct tgccttctct
     3721 tttatctcat atggcacaag tagaggggga agccaggagg aaattcatca cctcgctatg
     3781 cttttatttg atttttaatt cctgagtgcc taaatgtggt gaccggcacc tcacataact
     3841 ttttgagatt cttgatgtca tttttatcct tcctgtcaac cagcaatgta tttttatgtt
     3901 actaaaacca gtaacgtcat aattgttgag ggcaagcttc attgttgata gtgcaaagtg
     3961 tcgctgttgt gatgtgtgtt tattttattc aagtttgaat attgacaagt gtaacttaag
     4021 ctggtgactg acacctattg atctgctgtg tgcaaatgat agtactattt tttagaaaac
     4081 tcttaagtaa attttaaaaa tatttgaata caaaatatct gagcaatttt gaactcaaaa
     4141 gtttttcatt gttttaagga ttgccacagg actctttaat ggtttttaat ggacatacat
     4201 gcctaatatt tattggtgtg tttaaaatat tttttgatag agtgttatgt cttaagcgca
     4261 ttagaaaaca attgtttgta atggaatcaa agtgtttccc tggacagttt gatgtgctta
     4321 tggttgagat ttataatctg cttgtacttt gctttttaac ttattaactg taaataaatt
     4381 ttagagaata catagtgtct agtttttcta atgatttgaa catttttgaa atggtatttt
     4441 gtatttgtat gtgactcaga aaacatctta atttacaatt tgataaattt tgactttttt
     4501 gtgaacttca aattcccaga aatctcgaga tttgtttttt gtgctatctc gggagtctgt
     4561 gttccatcaa ttctttaatt atctagcgaa tttttaggat ggcgctacaa gcccaactta
     4621 ttaaccagtt tgccagcaat aaaatatcct acaaaaaaaa aatgcatcaa aattcagaat
     4681 tctctaaatc ctgacccgag gtgcccctgt gacgatgaca aaaggtctaa agctcttgct
     4741 ctttcatggc atgaaaggaa gtaagagtgc tccatttgag taccagtggt atgggctgtt
     4801 ccacagaata agggcagggc tagaattttc attagagtct agaaggcaga agtggagtat
     4861 tagtgaacag cacagcaaga gccggattca tagatagtac tgtgtgggct gaatttgtct
     4921 ttgtacctaa gttcctatta gttggaggaa gcgtagtgta atagttgtgg agtcacagtg
     4981 cctggggtgg aattattatg catacctttg tgacttgcaa gtgttgagac tgtaggtaag
     5041 ttacttaaaa tctttgtgcc ttgcttcctc aactatcaaa tgtgattagt gaaagaaact
     5101 attgggatat tataaggatt aataactacc cctttcaaag ggtagtaatg ctagacacat
     5161 aggaagtact aaataaatgc tcttaattat aggtatgcac agtgagaata ggtatataag
     5221 ctgagagtgg tccgttgtga gtttagctct ccaggtttct cagcatccca agaatattgt
     5281 gtggctctgg gaaagctgta agataaatga agagaagaga atttgtgcat gaataaaatt
     5341 gaagacataa ggaaatcata taatttttta gcttgctgac tatgcagtag gagattggat
     5401 taagttgatt tattacaatt tttgttgttg gagttttttt aaagattcac atcttctttt
     5461 gttatatctc tataagacat ttgaatgtac tgttatgtgt tttaaactat ctgagaattt
     5521 ataacagtaa tagatttaaa gctgttgatc caagaactta caaaagtttt ggactacata
     5581 tttgcttaga gtaagctcag taagtgttgc ttataaatga tgttaattta tatgcataga
     5641 accaagctat agtttgtata aagtttataa ttcaggtgtt aaaggaaaca aagtgagtac
     5701 aatagctgtg cttgaaacac cagaaaatta ttactgaaag taaaaaaaat cttgtatttg
     5761 aagcattgac acactcattt ttggatgtca gatataaagc ctgtaattta ggtttaattc
     5821 ctcatagcac agagaataga acatcctcta aattggtgaa caagccaaag ttgcagttat
     5881 ctgaagttga cacaaaataa tttcctggaa aattattaga tgaaagtcat acaagaacaa
     5941 gaagctaaaa attgagccta attgcagatt tcacagaagt aatgacttct cactgtcatc
     6001 actctcttgt gtcttggtaa atgtcattct aaaccatgat ctataacata ataaacatat
     6061 ctaaagccca attggaaagt aataatcata aaaacaccaa acactatgtt tagcccagaa
     6121 aatttgaata agtagtctac tgaatccaaa actggactta tttagcttcc gaaagcattc
     6181 atagaaaagt taaattgaga ttcttccaag tagtacaatt aactgtaaaa tgtgtacata
     6241 tttctctttt caaggatttt tttcaagtac atattcttta aagagtacag aaaaaaaaag
     6301 agtgtggctt agggttctaa atcttacaga gtaaaaaaat tattgaagca aaaacaaatg
     6361 tataaaaagt acatataaac gtacagtttg atgaattttc ataaattcaa taggctcatg
     6421 gaactagcac tcagattaaa aaaatacagt tatgagtacc cctgaagtcc tccctaacac
     6481 cccatcagcc attacctact caccttcttg cccaagataa ccattatttt gatttcttac
     6541 agcatatttt ttgcttattt ttgaacttta cataaatgga attattggtc atgtgtctag
     6601 cttctttcac ttgaaattat gtttgtgaga ttcatttata ttgttgtgtg tactattatt
     6661 gtagatcatt tattctcatt ggtgtataga attccactgt gtgaatattc cacaatatat
     6721 ttattccagt cttggtgggc atttgggtag attccagttt ggaacaatta taaataaagc
     6781 tttgatgaat attctaaaa
//
