LOCUS       NM_032600               1197 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 54 (CCDC54), mRNA.
ACCESSION   NM_032600
VERSION     NM_032600.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1197)
  AUTHORS   Dadabayev,A.R., Wang,Z., Zhang,Y., Zhang,J., Robinson,W.R. and
            Lim,S.H.
  TITLE     Cancer immunotherapy targeting Sp17: when should the laboratory
            findings be translated to the clinics?
  JOURNAL   Am J Hematol 80 (1), 6-11 (2005)
   PUBMED   16138340
  REMARK    GeneRIF: data supporting the rationale for further investigations
            of Sp17 for tumor vaccines in testicular cancer. (review)
            Review article
REFERENCE   2  (bases 1 to 1197)
  AUTHORS   Lea,I.A., Widgren,E.E. and O'Rand,M.G.
  TITLE     Association of sperm protein 17 with A-kinase anchoring protein 3
            in flagella
  JOURNAL   Reprod Biol Endocrinol 2, 57 (2004)
   PUBMED   15257753
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK058091.1 and AC063944.25.
            
            On May 17, 2019 this sequence version replaced NM_032600.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR5189667.406886.1,
                                        SRR5189667.134510.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000261058.3/ ENSP00000261058.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1196              AK058091.1         99-1294
            1197-1197           AC063944.25        116899-116899
FEATURES             Location/Qualifiers
     source          1..1197
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q13.12"
     gene            1..1197
                     /gene="CCDC54"
                     /gene_synonym="NYD-SP17; SP17"
                     /note="coiled-coil domain containing 54"
                     /db_xref="GeneID:84692"
                     /db_xref="HGNC:HGNC:30703"
     exon            1..1197
                     /gene="CCDC54"
                     /gene_synonym="NYD-SP17; SP17"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1136
                     /gene="CCDC54"
                     /gene_synonym="NYD-SP17; SP17"
                     /note="testes development-related NYD-SP17; testis
                     development protein NYD-SP17; sperm protein 17; testicular
                     tissue protein Li 33"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 54"
                     /protein_id="NP_115989.1"
                     /db_xref="CCDS:CCDS2949.1"
                     /db_xref="GeneID:84692"
                     /db_xref="HGNC:HGNC:30703"
                     /translation="MYTLHTKRVKAAARQMWTSNLSKVRQSLKNVYHKCKIRHQDSTG
                     YPTVTSDDCNQDDDSYDGKMNLPVVLQDVKTAQVELFSQMTDIVHMIPKVQEKTDLYQ
                     KQMEVLETRMNVNEDKQCTTTKDILSMKEDIKALKKKVTELEIQNSCSTIHCLEILEG
                     ERGKEITELLYKLIQPATLKNTLASTDMEISSAEPEKVPSYPKSTDHLEKKTISPQMK
                     TLKKRNHQNASRSFEKAKPNIYIYPDFSTWIKLTFVHGGKWTFFLSATKLEEFIQWLL
                     SRPTILPEEPQVITQRYCPFTGPILSLTTICLSIFNNIYGFICSLKEEVTRL"
     regulatory      1164..1169
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC54"
                     /gene_synonym="NYD-SP17; SP17"
                     /note="hexamer: AATAAA"
     polyA_site      1197
                     /gene="CCDC54"
                     /gene_synonym="NYD-SP17; SP17"
                     /note="major polyA site"
ORIGIN      
        1 attgctgtgg ctgatgattt ccagagtgtt ctaagatgtt atcaggaaag gcatccaaca
       61 aatagtaaga gaaggaccat ttcatttgta cattatttct tcctgtgatt ctgttttcca
      121 acaccttgcc tcttgtttca ccatgaaaga tgtacacact tcacaccaaa agggtaaaag
      181 ctgctgctag gcagatgtgg acttcaaatc tctccaaggt cagacagtct cttaaaaatg
      241 tttaccacaa atgtaagatt cggcaccaag attcaactgg atatcccact gtgacatctg
      301 atgattgtaa tcaagatgat gatagttatg acggaaaaat gaatcttcca gtagtgctcc
      361 aagatgttaa aactgctcaa gttgaacttt tcagccaaat gactgacatt gtccatatga
      421 taccaaaagt ccaggaaaag actgacttgt atcaaaaaca gatggaggtc ctggaaacca
      481 gaatgaatgt taatgaagac aaacaatgca caacgactaa agatatcctc tctatgaaag
      541 aagacatcaa ggcattaaag aagaaggtga cagaactgga aattcagaat tcctgctcca
      601 cgatacattg tctagagatt ctggagggag aaaggggtaa agaaatcaca gaactgcttt
      661 acaaactcat acaaccagca actctgaaga acactttggc ctctacagac atggaaatct
      721 cttcagcaga accagagaaa gtgcccagtt atccaaagtc cactgaccat cttgagaaaa
      781 aaacaatttc tccccaaatg aaaactctga agaaacgtaa ccatcaaaat gcatcaagga
      841 gctttgaaaa agcaaagcca aatatttaca tttacccaga cttcagtaca tggatcaagc
      901 taacttttgt tcatggagga aaatggacat ttttcctcag tgctaccaag ttagaagaat
      961 tcatccagtg gcttctttct aggccaacca ttcttcctga ggaaccccag gtcataaccc
     1021 agagatactg tccattcact gggcccattt tgagcttgac cacaatctgt ctctccatct
     1081 tcaacaatat ttacggcttt atttgttcct taaaagaaga agtaactcga ctatagagtt
     1141 atgttctgct ttgcttggca caaaataaat gtaacctgga ggctccaagt attcaca
//
