LOCUS       NM_152499               1472 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 24 (CCDC24), transcript
            variant 1, mRNA.
ACCESSION   NM_152499
VERSION     NM_152499.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1472)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL139220.13 and BC033868.1.
            
            On Nov 22, 2018 this sequence version replaced NM_152499.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC033868.1, BI770874.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000372318.8/ ENSP00000361392.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                AL139220.13        6890-6924
            36-1472             BC033868.1         27-1463
FEATURES             Location/Qualifiers
     source          1..1472
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.1"
     gene            1..1472
                     /gene="CCDC24"
                     /note="coiled-coil domain containing 24"
                     /db_xref="GeneID:149473"
                     /db_xref="HGNC:HGNC:28688"
     exon            1..148
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            149..306
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     CDS             181..1104
                     /gene="CCDC24"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 24"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 24 isoform
                     1"
                     /protein_id="NP_689712.1"
                     /db_xref="CCDS:CCDS507.1"
                     /db_xref="GeneID:149473"
                     /db_xref="HGNC:HGNC:28688"
                     /translation="MLRHSPSLWELVEEHVPLRERREVKRILGEAAVDLSLELRAEVA
                     MLRALLQEARSSQAPSSRPISDPSSLLAPPPLLKDLLRQELRQLLQGLRHKAICEGRD
                     QAQAWVQYSPRVLHFALEEPRCDLPEQEIFQMRGGGPSSGHRDLSIIKDQLNVSNIDQ
                     VARHLRGLLEEECHTLEREILILQRCLEEEYLRPCHPSEAALEPTLAELKEQKKAMEQ
                     ELQASVGPSCVSPNHRQRPLGSSTQGLRPPLPLCGVAPLQCCLPAPPLEPYLRPRGQS
                     ATHRWGRQLQCSPREGPASTPMSSAAPQAPA"
     exon            307..482
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            483..599
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            600..677
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            678..732
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            733..802
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            803..881
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1472
                     /gene="CCDC24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1450..1455
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC24"
                     /note="hexamer: ATTAAA"
     polyA_site      1472
                     /gene="CCDC24"
                     /note="major polyA site"
ORIGIN      
        1 agaggtgggg ctagggccct ggttcccact gcctggtttc tgggcccccg gcatccgagt
       61 cggccaaaag ccgggcagaa gagagcgcca aggactggca gttccggaac gggcaatccc
      121 agccgagggg accagcggca gagcacgggt ccgagccggg gacggcggcg tcggtgggtc
      181 atgctccggc actccccctc gctgtgggag ctggtggagg agcacgttcc gctccgggag
      241 cgacgcgaag tgaagaggat tctgggggag gcggcggtgg acctgagcct ggagctgcgg
      301 gcggaggtgg cgatgttacg ggcactgctc caagaggctc gatcctctca agcccccagc
      361 tcccgcccca tctctgaccc ctcttctctt ctggcaccac cgcctctcct aaaggacctc
      421 ttgcgccagg agctccggca gttgctccag ggtctccgcc acaaagccat ctgtgagggc
      481 agggaccagg cccaagcttg ggtccagtat agccccaggg tcctgcactt tgccttggag
      541 gagcccaggt gtgatttgcc agaacaggag atattccaga tgagaggtgg tgggcccagc
      601 agcggtcaca gagatctcag catcatcaag gaccaactga acgtgtccaa cattgaccag
      661 gtggccagac acctgagggg ccttctggag gaggagtgtc acaccttgga gagggagatc
      721 ctcatcctgc agcgctgcct ggaagaggag tatttgaggc cttgccaccc ctctgaggca
      781 gccctggagc ccaccctggc agagctaaag gaacagaaga aggccatgga gcaggagctg
      841 caggcatctg tggggccttc ttgtgtctct cccaaccaca ggcagcggcc cttggggtcc
      901 tccacacagg gcctcagacc cccgcttccc ctctgcgggg ttgcacctct ccagtgctgc
      961 ctgcctgcac ctcctctgga gccctacctt cgacctcgag gccagtcggc tacccaccgc
     1021 tggggacggc agcttcagtg cagccccagg gaagggccag cttccacacc catgtccagt
     1081 gcagcacccc aagccccagc ctgaagggct ggtcaccgag taggctctgg cttctgccac
     1141 agcgcacctg tctgccgctg ccgcctcagc tgctttggcc cagccagctt cagatctggt
     1201 cttggcgagc tctcgccagg accccaaggc tgttggtctg tctggccctt gccccacccc
     1261 cttgccagat ccctggtgtc tggagctgag tggccgggca tcggtcccaa gcatcaaagc
     1321 ctttggcctt tctcctccca ggcctccaca aaggcctggc agacagaggt ctcattccag
     1381 cctgactctt gtcccctggg ggacccagac aaagcacagc agccgctcag agacaggaat
     1441 agaaatttca ttaaaatcta tggactttaa aa
//
