LOCUS       NM_001363254             727 bp    mRNA    linear   PRI 04-AUG-2024
DEFINITION  Homo sapiens coiled-coil domain containing 200 (CCDC200),
            transcript variant 1, mRNA.
ACCESSION   NM_001363254
VERSION     NM_001363254.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 727)
  AUTHORS   Ulitsky,I., Shkumatava,A., Jan,C.H., Sive,H. and Bartel,D.P.
  TITLE     Conserved function of lincRNAs in vertebrate embryonic development
            despite rapid sequence evolution
  JOURNAL   Cell 147 (7), 1537-1550 (2011)
   PUBMED   22196729
  REMARK    Erratum:[Cell. 2012 Oct 26;151(3):684-6]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC024051.5.
            
            On Jan 3, 2020 this sequence version replaced NM_001363254.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189652.31379.1, ERR279828.1727.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148874, SAMEA2151119
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000636331.2/ ENSP00000490609.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC024051.5         100926-101099
            175-490             AC024051.5         105000-105315
            491-549             AC024051.5         105935-105993
            550-727             AC024051.5         107952-108129
FEATURES             Location/Qualifiers
     source          1..727
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.31"
     gene            1..727
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /note="coiled-coil domain containing 200"
                     /db_xref="GeneID:100874261"
                     /db_xref="HGNC:HGNC:43658"
     exon            1..174
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..576
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /note="TMEM106A antisense RNA 1 (non-protein coding);
                     TMEM106A antisense RNA 1 (tail to tail); long intergenic
                     non-protein coding RNA 854"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 200"
                     /protein_id="NP_001350183.1"
                     /db_xref="CCDS:CCDS92329.1"
                     /db_xref="GeneID:100874261"
                     /db_xref="HGNC:HGNC:43658"
                     /translation="MGSAYHWEARRRQMALDRRRWLMAQQQQELQQKEQELKNHQEEE
                     QQSEEKLQPHKKLNVPQPPVAKLWTSQEQPQPSQQQPSVQPPSQPPPQPSTLPQAQVW
                     PGPQPPQPQPPPQPTQPSAQARCTQHTSKCNLQDSQRPGLMNPCQSSPIRNTGYSQLK
                     STNYIQQW"
     exon            175..490
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            491..549
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            550..727
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      701..706
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /note="hexamer: AATAAA"
     polyA_site      727
                     /gene="CCDC200"
                     /gene_synonym="LINC00854; TMEM106A-AS1"
                     /note="major polyA site"
ORIGIN      
        1 agaggtggtg ggagcagtgg gctctgcctg tccccacccc cacctggggc ctcataccat
       61 cccactatca tgggtagtgc ctaccactgg gaggcccggc gccggcagat ggctttggac
      121 cgaaggagat ggctgatggc ccagcagcag caggagctgc agcagaaaga acaggaactg
      181 aagaatcacc aggaggaaga acaacaatcg gaggaaaaac tccagccaca taagaagtta
      241 aatgtgccgc aaccaccagt ggcgaaattg tggacatcac aggagcaacc acagccatca
      301 cagcagcagc catcagtgca gccaccatca cagccaccac cacagccatc aacattgcca
      361 caggcacagg tgtggccagg gccacagcca ccacaaccac agccaccacc tcagccaaca
      421 caaccaagtg ctcaagcccg ttgtactcag cacacctcca aatgcaatct ccaggattcc
      481 caaaggccag gtctcatgaa cccatgccaa tctagcccca tcagaaacac tgggtattca
      541 caactcaagt ctaccaatta catacagcag tggtgatcca gagattgaac ccaggacccc
      601 atggccatcc ccaaaatgca gatgagcaac cacatcttct cagcatccag caatatctcc
      661 actccaaaag ccacccactc tagaagagga ggctgccagg aataaaatgt aatttttttc
      721 ctgggaa
//
