LOCUS       NM_001395222            4056 bp    mRNA    linear   PRI 22-NOV-2023
DEFINITION  Homo sapiens coiled-coil domain containing 194 (CCDC194),
            transcript variant 2, mRNA.
ACCESSION   NM_001395222
VERSION     NM_001395222.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010319.10.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.1653125.1,
                                           SRR14038194.2564754.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968968,
                                           SAMEA2142348 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000636079.2/ ENSP00000490504.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-362               AC010319.10        97392-97753
            363-459             AC010319.10        99742-99838
            460-592             AC010319.10        100245-100377
            593-4056            AC010319.10        100929-104392
FEATURES             Location/Qualifiers
     source          1..4056
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.11"
     gene            1..4056
                     /gene="CCDC194"
                     /note="coiled-coil domain containing 194"
                     /db_xref="GeneID:110806280"
                     /db_xref="HGNC:HGNC:53438"
     exon            1..362
                     /gene="CCDC194"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..743
                     /gene="CCDC194"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2; coiled-coil domain-containing protein 194"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 194
                     isoform 2 precursor"
                     /protein_id="NP_001382151.1"
                     /db_xref="CCDS:CCDS92556.1"
                     /db_xref="GeneID:110806280"
                     /db_xref="HGNC:HGNC:53438"
                     /translation="MAEPGPEPGRAWRVLALCGVAVFLAAAAAGGALVAWNLAASAAR
                     GPRCPEPGANATAPPGDPPPGVDDLRRRLAEAAEREEALARQLDQAESIRHELEKALK
                     ACEGRQSRLQTQLTTLKIEMDEAKAQGTQMGAENGALTEALARWEAAATESTRRLDEA
                     LRRAGVAEAEGEACAAREAALRERLNVLEAEMSPQRRVPRPRPRSGSRPRPSPRSRSR
                     SGPSGGCRRPARRARG"
     exon            363..459
                     /gene="CCDC194"
                     /inference="alignment:Splign:2.1.0"
     exon            460..592
                     /gene="CCDC194"
                     /inference="alignment:Splign:2.1.0"
     exon            593..4056
                     /gene="CCDC194"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2849..2854
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC194"
                     /note="hexamer: AAGAAA"
     polyA_site      2868
                     /gene="CCDC194"
                     /note="major polyA site"
     regulatory      4032..4037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC194"
                     /note="hexamer: ATTAAA"
     polyA_site      4056
                     /gene="CCDC194"
ORIGIN      
        1 attcgtggcc gtctggggcc agagctgtgg accgcggcat ggccgagccg gggccggagc
       61 ccgggcgtgc ctggcgggtg ctcgccctgt gcggggtggc cgtgttcctg gctgcggcag
      121 cagccggcgg ggccctggta gcctggaatc tggccgcctc ggctgctcgg ggacctcgct
      181 gcccggagcc aggggccaat gccacggcgc cgcccgggga cccgccgcct ggggtcgacg
      241 acctgcggcg ccggctggca gaggctgccg agcgggagga ggccctagcc aggcagctgg
      301 accaggcgga aagtatccgg cacgagttgg agaaggcatt aaaggcctgt gaaggccgcc
      361 agagccggct tcagacccaa ctaacgacac tgaagattga gatggacgaa gccaaggcac
      421 aggggaccca gatgggggcc gagaacgggg cgctgacaga ggccctggcg cgctgggagg
      481 cggcggccac ggagtctacg cggcggctgg acgaggctct gcggcgcgca ggcgtggcgg
      541 aggccgaggg cgaagcctgt gcggcccggg aggcggcgct gcgcgaacgc cttaacgtcc
      601 tggaagccga gatgagccca cagcgcagag tgccccggcc gcgtccccgc tcggggtccc
      661 gaccccggcc cagccctcgc tcgcgctctc gctccggacc ctccgggggc tgccggcggc
      721 cggcgcggcg cgcacgaggg tgagtcggcc ccctgccgga agggggcgtc ggcctggagg
      781 acacatatgg ggggggggtc tgcggggacg tgtatagagg cacccccacg ctggatgcga
      841 cactcagctt tagaccctgg agacgtcctg aacggaaact gcacagaaag gtgcctcagc
      901 cctctctccc ccaccatgta aagtgcttat tctacagaca gggaaactga ggcccaagtg
      961 atcatgcagt gagctagtgc ttagctggga tttgaagtcc cctctaacaa caatgttgcc
     1021 gtcatcccac agatatgagg actggaggtc tagccctggc tcaggaaaaa ccggaaaggg
     1081 tcactttccc tctttgggtt tcagtttacc ctatctgtaa aatgggtgat tggactcatg
     1141 atagggagct gatttgacaa caaaagctga caaaggtggc acaataggaa aaccgcaaat
     1201 ccctaaccct gtgagaaggg tacaaaactc ccagatggaa tttaaacaaa aagaaccaag
     1261 taacatgttt gttttggttt ggttttgaga tggagttttg ctgttgtcgc ccaggctgga
     1321 gtgcagtggc acaatttggg ctcactgcaa ccttcacctc ccaggttcaa gcaattctcc
     1381 tgcctcagcc tcccaggtag ctgggattac aggcccccac cactacgccc agctgatttt
     1441 tgtattttta gtagagacgg ggttacacca tgttggccag gctggtctcg aactcctgag
     1501 cttaggtgat ccgcccaccc ggcctcccaa agtgctggga ttacaggtgt gagccaccgc
     1561 tcccagccca tgtttttaac ctacactgca acaaaggtga cttatgcctg agacagagca
     1621 atggttcaat attgccaagt ctgttaattg ctatactaat agatcaaatg aggaaatgta
     1681 taaattgtgg gggaaaaaac acatcaaaat cagtgccaag gtgaggacgt ccactgtcaa
     1741 gtagtttttt ttctgggagt acaagccaat gcaattacac aagaaaaata aaagctacaa
     1801 ctaaaaggaa gagaatctgt aggttgaatc acaagaaaga gctgtttata tgggtcaaaa
     1861 atcattgaaa tatggacaat tttatattgc tcaatttcac atgaatgtat tagtgggttt
     1921 tcttgttttt ctaaccttta aacattttta gcttgttatc taaatttaac ctttatattt
     1981 ggcataactt cagacttaca gaaaatttgg tggattaatc tccaactcct taacaacaca
     2041 aaggttatgg gcaccagttc tccatgcagt tgaaaattca cacataactt tgactcctcc
     2101 aaactcaaag ctggccaggt gtggtggctc acgcctgtaa tcccaacatt ttgggaggcc
     2161 acagcaagaa gatcacttga gcccaggagt tcaagaccag cctgggcacc atagcaagaa
     2221 cctgtctcta caaataatat caataattag ctgagcatgg tgacatgcat ctgtagcccc
     2281 agctacttgg gaggctgagg cgggaggatc acttgagccc aggacgtcaa gtttgcagtg
     2341 agccatgatc acaccactgc acttcagtcc tctgagtgac agagcaagac ccggtctcaa
     2401 aaattaaaca tgaaaaatta aagctataaa aaaattatta agaaaatcat gctgggcaca
     2461 gtggttcatg cctgtaagcc caatactttg ggaggctaag gcgggaggat ctcttgagcc
     2521 ctgaagttca agaccagtct gggcaacata gggagaccct gtctctacaa ataattgttt
     2581 caaaattctt tgggaggctg aggcgggtgg atcacttgag ctcaggtgtt tgagaccagc
     2641 ctgggcaaca tggtgaaacc cattctctac caaaaataca aaatattagc tgggcatggt
     2701 ggcatgcacc tgtggtccca tctacttcgg agactgaggt gggaggatca cttgagcctg
     2761 ggaggcagag gctgcagtga gccaagatcg tgctagggtg actggagcaa aaccccttca
     2821 agaaaagaaa gaagagaaag aaagaaaaaa gaaagacaaa aaagaaaaga aagaaagaga
     2881 agaaagtagc caggcttggt ggcatgcacc tgtggtccca gctacttggg aggctgaagc
     2941 aggaagatca cttaagccca ggaggtggaa gctgcagtga gccatgatca tgccactgca
     3001 ctccagccta ggtgactgag tgagatcctg tctcaaaaaa aaaaaaaaaa aaaaaaaagg
     3061 aaaaaaagag cccgggggtg gctcacgcct gtaatcccag cactttggga ggccgaggcg
     3121 ggcggatcac gaggtcagga gatcgagacc atcctggcta acacggtgaa accctttctc
     3181 tattaaaaat acaaaaaatt agccgggcat ggtggtgggc atctgtagtc ccagctactt
     3241 gggaggctga ggcgggagaa tggcatgaac ctgggaggcg gagcttgcag tgatctgaga
     3301 tcgcaccact gcactccagc ctgggtgaca gagtgagact ctgtctcaaa aaaaataaaa
     3361 ataaatagaa aagaaagaca gaaaaagaaa aagtgtctgt ccatccacag tggaacgcta
     3421 tgcaaccacc atttaaacag ccaaagcaga tcttctctaa gatatgttaa tgtgaaaagc
     3481 aggagattga taagttgtgt actttctttc tttctttctt tttttttctt tttgagatag
     3541 agtcttgctt ttgttgccca ggctggagtg caatggcgca gtctcagctc actgcaacct
     3601 ccgcctctcg ggttcaaacg attctcttgc ctcagcctcg agtaactgga attacaggcg
     3661 cccatcacca gactcagcta gttttttgtg ttttttagta aagacggggt ttcaccatgt
     3721 tggccaggct ggtctcgaat tgctaacctc gggtgatcca ccctccttgg cctcccaaag
     3781 tgctgggatt acaggcctga gccgctgtgc ccggcccccg tttttgtgtg tgtgtgtgtg
     3841 tgtagggctt ggggagggga cttttatcca aatatctctg aaggagatgc tggtcacagc
     3901 ctccacctct ggggagcgaa ccaggggtct gggaatcggt gggggacata cttgcacatt
     3961 tctctatgta ccttttgtaa aaattgcatt tttaaaaacc atgcacatgt gtcacttatt
     4021 acaaattaaa aattaaaaat tgtttttaaa aatgtc
//
