LOCUS       NM_020817               3889 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 191 (CCDC191),
            transcript variant 1, mRNA.
ACCESSION   NM_020817
VERSION     NM_020817.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3889)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3889)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092896.9 and AC128687.10.
            
            On Nov 23, 2018 this sequence version replaced NM_020817.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF509494.1, SRR1660803.33575.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000295878.8/ ENSP00000295878.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-150               AC092896.9         51818-51967         c
            151-189             AC092896.9         49038-49076         c
            190-331             AC092896.9         42032-42173         c
            332-475             AC092896.9         38144-38287         c
            476-654             AC092896.9         32049-32227         c
            655-878             AC092896.9         30366-30589         c
            879-1032            AC092896.9         27067-27220         c
            1033-1223           AC092896.9         14119-14309         c
            1224-1473           AC092896.9         6213-6462           c
            1474-1928           AC128687.10        602-1056
            1929-2038           AC128687.10        1818-1927
            2039-2121           AC128687.10        4026-4108
            2122-2223           AC128687.10        4868-4969
            2224-2367           AC128687.10        25771-25914
            2368-2520           AC128687.10        27554-27706
            2521-2666           AC128687.10        28233-28378
            2667-3889           AC128687.10        41205-42427
FEATURES             Location/Qualifiers
     source          1..3889
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q13.31"
     gene            1..3889
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /note="coiled-coil domain containing 191"
                     /db_xref="GeneID:57577"
                     /db_xref="HGNC:HGNC:29272"
     exon            1..150
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..2871
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 191"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 191
                     isoform 1"
                     /protein_id="NP_065868.1"
                     /db_xref="CCDS:CCDS2977.1"
                     /db_xref="GeneID:57577"
                     /db_xref="HGNC:HGNC:29272"
                     /translation="MLLAPQGRSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKR
                     VEKASEFAVSNAFFTRNSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTK
                     LKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHL
                     LHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKT
                     LKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKK
                     RQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWH
                     KLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQL
                     ATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGL
                     SGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQ
                     NVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQ
                     KKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNS
                     PVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQ
                     EEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIA
                     KEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARK
                     MAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDS
                     QGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEILPDFQVPG
                     RYHELYQQSDTWSLSKTSLVNE"
     exon            151..189
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            190..331
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            332..475
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            476..654
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            655..878
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1032
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1223
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1473
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1928
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2038
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2121
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            2122..2223
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            2224..2367
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2520
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..2666
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     exon            2667..3889
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3862..3867
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /note="hexamer: AATAAA"
     polyA_site      3889
                     /gene="CCDC191"
                     /gene_synonym="KIAA1407"
                     /note="major polyA site"
ORIGIN      
        1 agcccgggca gaagggcggt tgctgcagct ttggccgagg ttcgggctcg aacttggaaa
       61 atgctcctgg cgcctcaggg aaggtccttc tcaaagaaaa ggatggggct gaatcgctgg
      121 aaacggttca caaggaagcc gagtcccaag cctacttttg gtcctgacag tgtggaacac
      181 tggataaaga gagtggagaa agcctcagag tttgcagtgt caaatgcatt ttttactaga
      241 aattcagatt tacctagaag tccctggggc caaatcacag atttgaaaac atctgagcaa
      301 atagaggatc atgatgaaat ctatgcagaa gctcaggagc tggtcaatga ctggttagac
      361 accaaactta agcaagaatt agcaagtgag gaagaaggtg atgctaaaaa cactgtgtca
      421 agtgtcacta ttatgccgga agccaatggc catttgaaat atgacaagtt tgatgattta
      481 tgtggctatt tggaggaaga agaggaaagt accaccgttc aaaaatttat agaccatctg
      541 ctccataaaa atgtggtaga ttctgcaatg atggaagatc ttggaaggaa ggaaaaccaa
      601 gacaagaagc agcagaagga tcctcgtctt accatggaga tgagacataa gcaggtaaaa
      661 gaaaatcgct taagacgtga gaaagaactg gagtaccaga gaatagaaaa gaccctgaaa
      721 aaatcggcct tcttggaggc tcagtgtctg gtgcaagaag agaagaaaag gaaggctctg
      781 gaggccaaga aagaggaaga ggagattcaa agggagatgg tgaagctgcg gagggagata
      841 attgagagga gacgcactgt gaaagcagca tggaaaatag agaagaaaag gcaagaagag
      901 aattctcaaa atagttcaga aaaagtcatg tttcaaagta ctcacattct tccagatgag
      961 gaaaaaatgg tgaaggaaag aaaaaggaaa ttgaaagaag tattaatcca aactttcaaa
     1021 gaaaatcaac agtgtcaaaa acggtatttc gctgcctggc acaagctgat tcttgatcat
     1081 aggattaagc tggggaaagc tgggaccctg tctgactgga agattcagct gaaggtcctg
     1141 cgggcctgga gagactacac aagattccag aagttggagc gggagactca agccttggaa
     1201 aatgatctta gggaagaaaa cagaaaacaa caactggcca ctgagtataa ccggaaacaa
     1261 gttctccgac actgctttac agaatggcag cattggcatg gcgccgagct cctgaagaga
     1321 gagctggctc tcacaaaaga ggaaactagg aagaagatgg atgcactgct gcaggcagca
     1381 tcactgggga aactcagtgc caatgggtta tcaggcatca gtctacctga ggaggcaaca
     1441 gccatggtgg gtccaccagt aaaaaatgga caggagactg ctgtgccccc tttgtgggaa
     1501 aagcctccct tgggaagcag tggttgtatg ctcagtcctc ccctgggaag aacaacaaca
     1561 ggcaacttgc agggttccct tcagaatgtc tctctgagtg cacctggcaa taagcagcac
     1621 aagaccctgg gtgctgaacc ctctcaacag cctggcagca acgagacact cagaactacc
     1681 agccagaaag cagaaccgct ttgcttgggt catttccaca accgccatgt cttccagcaa
     1741 cagctgattg agaagcaaaa gaagaaactt caggaacagc agaaaacaat tctcgagctg
     1801 aagaaaaacc tgcagctggc agaggctcag tgggcagcag agcatgcctt agcagtcaca
     1861 gaagcacaga gccacctgct gtcaaagccc agagaagagg aaccaagaac ctgccagatg
     1921 cttgtgaatt cacctgttgc ttcccctggg actgaaggca gaagtgactc ccgaaattct
     1981 ctttctggac tcagaaggaa accaaagcaa ttgatgacac cgcatcccat actaaaagct
     2041 atggaagaga gagcaattca acgagctgaa tgtaggcgga tcttggcaga gaagaagaaa
     2101 aaacaagaag aagaaaaatt ggcccagtta aaggcccaag aggaggaacg tcagaaaagg
     2161 gaggcagaag aaaaggaggc acagcttgaa agaaaacgag aagagaagag actgaagaaa
     2221 atgaaagaac ttgagaagca gaagagaatt aagaggaacc agcagctgga agcaatagcc
     2281 aaagaacatt atgaaagggt cttgctaagg aaaaaaggtc tagagccttg gaagagattg
     2341 agaatgcaaa gcaaacaaaa catccaggtg gcagaagaac attactcttt gttcctgcag
     2401 aggaaataca tgctgacgtg gttccagcgt agtcaggaaa gtctggctag aaagatggcc
     2461 caggctgatc aattttattc ccaaatactg cttaagagag tcatccagag ctggctacag
     2521 tacgtgattg atctgcagga agaagtaaga aaattttgtg tacattttct tcaaaagaag
     2581 attttcaggg cctggtttaa catggtcagg gaggtgaaga tcgattctca gggcaagcat
     2641 gagattgcag cggagcacag tgacaggagg atcctctgga tcacccttcg gacatggaag
     2701 aagtttgtaa aatttatgaa agaggaaaga gtaaaagaag aaaggcgaca gcaacttcgt
     2761 aggaaggtag ttgaaattct tccagacttc caggtacctg gaaggtacca cgagctatat
     2821 cagcaatcag atacttggtc cttgagtaag acaagtctgg tgaacgaatg agccagatta
     2881 gtgtaatatt taggacagga agctcgacta gtctgtatgt gtgttatctc cacccaccca
     2941 cacacataca tacatacacc tggtttattc tctacgagct acttcttaga tcaaaggaat
     3001 tattttgaga atttttattc ccttctttga cttttcctgg attgctagtc attcactata
     3061 gcatttatca cagtgggatc atccaaagga acattctaga gatcgtctgt tcaaatatat
     3121 cctatatatt tttagcatag taaactttaa aaaggacaag tgtttgcctg actgagcctg
     3181 tgaagaaaat gtgtccgtat agcacgacag gagttgctga tgtgacctta atgaaacaga
     3241 aataaacagg ggtgagtgct cggaaaggaa gggcgggcca aggcactcag ccttctagtg
     3301 cagtagcatc agtgacacgc accccaccag acctcgtcca ctttcaccac ccctgaaggc
     3361 agaccatgta tgaaaaggtt ctctacacag ctgctgcaga ggacagcagc ttatcctgat
     3421 ttcagagaaa ctgaggcacc agagatgctt ctcttccgtg caccttgata agcatgaagg
     3481 acattccaaa aggtaatagc tctatcatga cagtccagca attcattaaa ttatctgttc
     3541 atgctcccac ctgcaactgc tgaataatac actcagtttg tcttctagta ctcagctcag
     3601 tttgatctag atattgagat acctatcttg aattcaaaga atgttttcat ctttaagatg
     3661 ctataaagac tgataaaatg ctctcttcta tgaattgtgt tagagaatta cctgctagaa
     3721 aaataatttt tcattataaa atacacattt attatataac aaattcaagt agtccataaa
     3781 tgcatatggt aaaatgagaa agtcctgtgc agtcctgaga tgattactct tatttggtgt
     3841 gctgaaaatt tgagttgaca aaataaaatt ctgtggtttt ttaagtgaa
//
