LOCUS       NM_001365892            1476 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens coiled-coil domain containing 188 (CCDC188), mRNA.
ACCESSION   NM_001365892 XM_005261240
VERSION     NM_001365892.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006547.9.
            
            On May 17, 2019 this sequence version replaced NM_001365892.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1968189
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000439765.4/ ENSP00000409542.2
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-588               AC006547.9         111499-112086       c
            589-696             AC006547.9         111174-111281       c
            697-801             AC006547.9         110986-111090       c
            802-858             AC006547.9         110755-110811       c
            859-918             AC006547.9         110612-110671       c
            919-983             AC006547.9         110443-110507       c
            984-1041            AC006547.9         110218-110275       c
            1042-1091           AC006547.9         109906-109955       c
            1092-1476           AC006547.9         109447-109831       c
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     gene            1..1476
                     /gene="CCDC188"
                     /note="coiled-coil domain containing 188"
                     /db_xref="GeneID:388849"
                     /db_xref="HGNC:HGNC:51899"
     exon            1..588
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..1278
                     /gene="CCDC188"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 188"
                     /protein_id="NP_001352821.1"
                     /db_xref="CCDS:CCDS93123.1"
                     /db_xref="GeneID:388849"
                     /db_xref="HGNC:HGNC:51899"
                     /translation="MEGLKTLGPCGHPHPQCPPTPASSSHGGGLDQPCQGFVGWPCLG
                     PISSAHSVQSQRPFPVPGAGGSGPTVEGEAPGLFLSSQEQRARDTEGPRQGDLEAGLG
                     WGWPLHPGSNQGAPRQGGSIGSGTRPCPCPPLSREGGALASPRVALSQLQCGLLGSAE
                     QSFLQLEQENHSLKRQNQELREQLGALLGPGQQFLPLCPEHSSCTALAWPPDPAGTQP
                     LGNRAPLQLLRRELCQGQEAFVQQSQNELQQIRLCFERKKMVITEVWDNVAEMHMALN
                     NQATGLLNLKKDIRGVLDQMEDIQLEILRERAQCRTRARKEKQMASMSKGRPKLGSSK
                     GLAGQLWLLTLRLLLGALLVWTAAYVYVVNPTPFEGLVPPLLSRATVWKLRALLDPFL
                     RLKVDGFLPF"
     exon            589..696
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            697..801
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            802..858
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            859..918
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            919..983
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1041
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1091
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1476
                     /gene="CCDC188"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1476
                     /gene="CCDC188"
                     /note="major polyA site"
ORIGIN      
        1 agtaagaggg tggcaggttg ggccaggcca gagcctggac ctgggatcag gaaggggttg
       61 cagggaggga tggaggggct gaaaaccctg ggcccctgcg gccaccccca cccccagtgt
      121 cccccaaccc cagcctccag cagccatgga ggaggcctgg accagccctg ccagggattt
      181 gtagggtggc cctgcctggg ccccatctcc tctgctcact cagtgcagtc ccagagacct
      241 ttcccagtcc caggggcagg gggcagtggg cccacagtgg agggcgaggc tcccgggctc
      301 tttctgtcca gccaggagca gagagcgaga gacactgagg ggccgagaca aggagacctg
      361 gaggcagggc ttgggtgggg ctggcccctg cacccagggt cgaaccaggg ggctcccagg
      421 caggggggat ccattggctc agggaccaga ccctgcccat gcccacccct gtcacgggag
      481 ggaggggccc tggcctcgcc cagggtagcc ctgtcccagc ttcagtgcgg gctgctgggc
      541 tctgcagaac agtccttcct gcagctggag caggagaacc acagcctgaa aaggcagaat
      601 caggaacttc gggagcagct gggggccctc ctggggccgg ggcagcagtt cctgcccctg
      661 tgtcccgaac actcaagctg cactgctctg gcctggcccc ccgacccggc tggcacgcag
      721 cccttgggga acagggcacc tctgcagctg ctgcggcggg agctgtgcca ggggcaagag
      781 gctttcgtgc aacagtccca gaacgagctg cagcagatcc gcctgtgctt tgagaggaag
      841 aagatggtca tcacagaggt gtgggacaac gtggctgaga tgcacatggc cctgaacaac
      901 caggccaccg ggctcctgaa cctcaagaag gacatccggg gcgtgctgga ccagatggag
      961 gacatccagc tggagattct cagggagcgg gcccagtgcc gcactcgagc caggaaggag
     1021 aagcagatgg caagcatgtc gaaagggagg ccaaagctgg gaagctccaa gggcctggca
     1081 ggccagctct ggctgctgac cctgaggctg ctgctgggcg ccctgctggt ctggaccgct
     1141 gcctacgtgt acgtggtgaa ccccacacct ttcgaggggc tggtgccacc cctgctgagc
     1201 cgtgccaccg tctggaagct ccgggccctg ctggacccct tcctgcgcct caaagtggac
     1261 ggcttcctgc ccttctaggc cagaggccca gcggccccag caaggaggcc aggcgaccag
     1321 cactgccccg gatgcccagt ggccgtgcca gccccctgca catggcacca ctgtgcacca
     1381 tccttgccag aagctgcaga gaagggtgga ggtggggtct gtcctgaggg ctgggcctgt
     1441 ggctggacat agaatcatga cataagtggc cggtga
//
