LOCUS       NM_152610               2051 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens coiled-coil domain containing 185 (CCDC185), mRNA.
ACCESSION   NM_152610
VERSION     NM_152610.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2051)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB446947.1, AK093047.1 and BC031066.1.
            
            On May 17, 2019 this sequence version replaced NM_152610.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC030026.1, AK093047.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000366875.5/ ENSP00000355840.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 DB446947.1         43-44
            3-11                AK093047.1         1-9
            12-1046             BC031066.1         1-1035
            1047-2049           AK093047.1         1045-2047
            2050-2051           BC031066.1         2039-2040
FEATURES             Location/Qualifiers
     source          1..2051
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q41"
     gene            1..2051
                     /gene="CCDC185"
                     /gene_synonym="C1orf65"
                     /note="coiled-coil domain containing 185"
                     /db_xref="GeneID:164127"
                     /db_xref="HGNC:HGNC:26654"
     exon            1..2051
                     /gene="CCDC185"
                     /gene_synonym="C1orf65"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..1933
                     /gene="CCDC185"
                     /gene_synonym="C1orf65"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 185"
                     /protein_id="NP_689823.2"
                     /db_xref="CCDS:CCDS1537.1"
                     /db_xref="GeneID:164127"
                     /db_xref="HGNC:HGNC:26654"
                     /translation="MAGFSHFSQPPYRDLWEPPRPGGERESTQRLGGQRSGADSTACS
                     RAGTPGAESEAGACWLHPHCSFTPRPRRRGCSDSLRGSRSLSDVARRPLERSRKHRPR
                     SRRLEDAWGETGTKPRPAWQPQTQLPPQRPQPCPHYPLAQGDSPPPCPGGAGTPLSGT
                     FRVEKAQGGDQWAVPLGRHLGRWSPSSVPSERSSVPSQKFKRHSACVCAQKRDSSDQV
                     ESLASRDSQPLASSKEMRSPHTQVLKSKLEEVVVSSQDQQIVALVLTRLKKAQRIREL
                     QQQAAKAWEELKRSDQKVQMTLERERRLLLRQSQEQWQEKEQRKTLQSPEQRGLRRDS
                     QRKNVPPGESRWKEQPEDQESPRQEKLEKARAQAEHRKQCQVRRLREQEKMLRNLREQ
                     HSLQLQRRLVEACRKRHLHAVEGQKKVQDTNLSSLINYQARKVLMDCQAKAEELLRQL
                     SLEQSFQRSQEIHQGLRKERQRELREKAQKEEEQLQQARWRAGESEEQRKMRKRILVE
                     LADEKIRQARSHVHKTTRDKVQHLRELNHLREKNHHILKLKAEKEEKCHIEGIKEAIK
                     KKEQRVQHISQGKDPNFQEFQKLPQASRREERAPPNSSLDQMVLEAQLRACQQNRGY"
     polyA_site      2051
                     /gene="CCDC185"
                     /gene_synonym="C1orf65"
                     /note="major polyA site"
ORIGIN      
        1 gcagcgtcct cgggaggtct caggcccctt gggcagacgc tgcgcgtgcc cagagggagg
       61 gatggcaggc ttcagccact tctcccagcc gccctaccgg gatctctggg aacccccgcg
      121 gcccggcgga gaacgagagt ccacgcagcg gctgggcggg cagaggtccg gagccgactc
      181 caccgcgtgc tcccgggccg ggactccggg tgcggagagc gaagctgggg cgtgctggct
      241 gcacccgcac tgttcgttca ccccgcggcc tcgcaggcgc gggtgctcag attcactgcg
      301 gggcagccga agcctgagcg atgtggcccg caggcccctg gaacgttcca ggaagcaccg
      361 gccccgcagc aggcgcctgg aagatgcctg gggagagaca ggaaccaagc cccgcccggc
      421 ttggcagccg cagacccagc tgccacccca gcggccgcag ccctgcccgc attaccctct
      481 ggcccaggga gactcgcccc cgccttgccc cggaggagct ggcactcccc tgagtggcac
      541 attcagggta gaaaaggcac agggtggaga ccagtgggca gtgccactcg gcagacatct
      601 aggtcgctgg tccccttcct cagttccctc ggagcggtct tctgtgccct cgcaaaagtt
      661 caagaggcac tcagcctgcg tgtgcgccca gaagagagac agcagcgacc aggttgagtc
      721 attagccagc cgggactccc agcccttggc ctccagcaaa gagatgcgga gcccgcacac
      781 ccaggtcctg aagagcaagc tggaagaggt ggtggtgtcc tcccaggacc agcagattgt
      841 ggccctggtg ctgacccgtc tcaagaaggc ccagaggata cgggagctgc agcagcaggc
      901 ggctaaggcc tgggaggagc tgaagcgctc ggatcagaag gtccagatga ccctggagcg
      961 ggagcgccgg ctgctgctgc ggcagagcca ggagcagtgg caggagaagg agcagcgcaa
     1021 gaccctccag agccctgagc agcgcggcct gcggcgggac agccagagga agaacgtgcc
     1081 cccgggggaa agccggtgga aggagcaacc agaggaccag gagagcccgc gccaggagaa
     1141 gctggagaag gcgcgcgccc aggcagagca ccgaaaacag tgccaggtgc ggcgcctgcg
     1201 ggagcaggag aagatgctac ggaacctccg ggagcagcac agcctgcagc tgcagaggag
     1261 gctggtggaa gcctgtcgca agaggcacct acatgccgtg gagggccaga agaaggtcca
     1321 ggacaccaac ctgagctccc tcatcaatta ccaggcccgg aaggtcctca tggactgcca
     1381 ggccaaggct gaggagctcc ttaggcagct gtccctggaa caaagtttcc agcggtccca
     1441 ggagatacac cagggcctga ggaaggagcg gcaacgcgag ctgagggaga aggcccagaa
     1501 ggaggaagag cagttgcagc aggccaggtg gcgcgcaggg gagtcagagg aacagaggaa
     1561 gatgcgcaaa agaattctgg tggagctggc ggatgagaag atccgacagg ccaggagtca
     1621 cgtgcacaag accactaggg acaaggtgca gcacctccgg gagctcaacc acctgaggga
     1681 gaaaaaccac cacatcctga aactgaaagc cgagaaggag gaaaagtgtc acattgaggg
     1741 catcaaggag gccattaaga aaaaggagca gagggtgcag cacatttccc aagggaaaga
     1801 cccaaacttc caggagttcc agaagctccc tcaggcctcc aggagagagg agagagcgcc
     1861 tcccaacagc tcccttgatc agatggtact agaggcccag ctccgtgcct gtcagcagaa
     1921 caggggttac tgagaaccaa ggacgcctgg cttacagtgc gcagccagaa ggagatgtgg
     1981 caatgtgatt ccttttgtaa tctgattata attgaacatt gattttaaaa aagcatgtaa
     2041 aatagctgca a
//
