LOCUS       NM_001013635            2283 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 184 (CCDC184), mRNA.
ACCESSION   NM_001013635 XM_370691
VERSION     NM_001013635.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2283)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2283)
  AUTHORS   Pensold,D. and Zimmer,G.
  TITLE     Single-Cell Transcriptomics Reveals Regulators of Neuronal
            Migration and Maturation During Brain Development
  JOURNAL   J Exp Neurosci 12, 1179069518760783 (2018)
   PUBMED   29551912
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2283)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB483736.1, BC036801.1 and AK056783.1.
            
            On May 17, 2019 this sequence version replaced NM_001013635.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR3476690.126215.1, BC036801.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000316554.5/ ENSP00000320849.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-362               DB483736.1         62-423
            363-898             BC036801.1         375-910
            899-2197            AK056783.1         434-1732
            2198-2283           BC036801.1         2210-2295
FEATURES             Location/Qualifiers
     source          1..2283
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.11"
     gene            1..2283
                     /gene="CCDC184"
                     /gene_synonym="C12orf68"
                     /note="coiled-coil domain containing 184"
                     /db_xref="GeneID:387856"
                     /db_xref="HGNC:HGNC:33749"
     exon            1..2283
                     /gene="CCDC184"
                     /gene_synonym="C12orf68"
                     /inference="alignment:Splign:2.1.0"
     CDS             480..1064
                     /gene="CCDC184"
                     /gene_synonym="C12orf68"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 184"
                     /protein_id="NP_001013657.3"
                     /db_xref="CCDS:CCDS31785.1"
                     /db_xref="GeneID:387856"
                     /db_xref="HGNC:HGNC:33749"
                     /translation="MEDGLLEIMTKDGGDMPAPLEVSTVPAVGDVISGEYNGGMKELM
                     EHLKAQLQALFEDVRAMRGALDEQASHIQVLSDDVCANQRAIVSMCQIMTTAPRQGGL
                     GVVGGKGSFQSDPQEPETPSPGIGDSGLLGRDPEDEEEEEEEKEMPSPATPSSHCERP
                     ESPCAGLLGGDGPLVEPLDMPDITLLQLEGEASL"
     regulatory      2260..2265
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC184"
                     /gene_synonym="C12orf68"
                     /note="hexamer: AATAAA"
     polyA_site      2283
                     /gene="CCDC184"
                     /gene_synonym="C12orf68"
                     /note="major polyA site"
ORIGIN      
        1 accccagctg ctgctgccac actcgcgggc gctgcccggt aatggcctgg gggagtcccg
       61 agtccgacgc gccgctggcc tcagcctgga cgcggacccc tccgcgagcg cgtctgtgac
      121 ccacggaacc ggcaggcgct ctctgcttgt ggcgcccaga gggcggcgct gacacgggcg
      181 cgatccggga ggcgaggcag ggcagggcac tttcgtcccg gggcgatccc aagagacgcc
      241 ggctctggga ccctcgccgg gtcctcgtcc cgcagcctct tctcggcctc ccgcgatcct
      301 gcctgcgccc tctgcccagg actcgtctct cacgtcggct ccccgccagt ctcgggagcc
      361 tccgcttccc tcggctcccg ctagcccctc ccgggacctc tccccctcca ccccctcccc
      421 caccccggag gccgggctgg acgcgaccca gagcctccgc cacccgcttc tgccactcaa
      481 tggaggacgg tctgctggag atcatgacca aggacggcgg cgacatgccg gcgcccctgg
      541 aggtgtccac cgtgccggca gtgggggacg tgatctccgg ggagtacaac ggcggcatga
      601 aggaactgat ggagcacctg aaagcccagc tgcaagccct gtttgaggac gtgagggcca
      661 tgaggggggc cctggacgag caggcctcgc acatccaggt gctctcggac gacgtgtgcg
      721 ccaaccagcg agccatcgtc tccatgtgcc agattatgac cactgcgccc cgccagggcg
      781 gcttgggcgt ggtcggcggc aaggggagct tccagagcga cccccaagag ccggagactc
      841 cttcgcctgg gatcggggac agcggcttgc tgggtcgcga tcccgaggac gaggaggaag
      901 aggaagaaga gaaggagatg cccagccccg ccacaccctc cagtcactgt gagcgccccg
      961 aaagcccctg tgctggtctc cttggggggg acgggccact tgtggagccc ctcgacatgc
     1021 ccgacattac cctgctgcaa ctggagggcg aggcctccct gtgaggggac tccgtggggc
     1081 actaccttcc cgggctgtct ttgggtttcc gagtgcatga cgcgaggggg actgaacggc
     1141 gcggtgcggc atgcttcact tggacagctg ctcttgtggg tcaggcagag agagactccc
     1201 tcgaggaagg atttgtaggg tgaaggactt tgggagcatc gagaattctt tctgcccaac
     1261 taagcgaatt atagcgaact gcggaaaggt gaggctccgg gagaggaagc gcccatctct
     1321 ggactcccat ccatccctat cctgtccttt cccccttccc agacaacagg agaacccgtg
     1381 aattgtgtaa ataaaattct gctttttcta ttctgaaaaa ggacttacct aggaccatgg
     1441 caaataatct ctaacaattt acctggaaat taaggaattg ggggtatttt gttctggcaa
     1501 caggaaattt acccttctgc tgaaatccaa gatattcagt gctctgcaga agcctctccc
     1561 cctcacagat ctctgcggct gctgattggt aaaggaagct tgaggaggga actgcagccc
     1621 taggaatctg ggtgaatggg gttccaaggg cccctgggct gggaggagct ggctatgaat
     1681 gtgcatgaag acataatagc tcaacctcta ggattttgca tgcagagcgg atcctgcctt
     1741 gtcactgact tcatctggga ttgcttttcc actccctggg gcttagagaa caaagagccc
     1801 ggttcacagg cagagactcg ggggtgctca gcagcagccc agatttaggg gacatttgag
     1861 ggactcttgg ggccgcagcc aaaaactgtc tctcctggct acacctgctt aacttcagtt
     1921 cctttttctg tcaatatgtc cttgcccact gcctctcggt gttgccttca taatgtcttg
     1981 tgtgtgttat gtgtgtctac ttgtgtagta gtgtgtgagc cctcaggggc agggcttgtg
     2041 gctctggtgt taggttcagg ggcttcagac ccttctacga gctccaagct atcaatggcg
     2101 cttttctctc cctcttcccc caaccagggc atggagcatg tggctgtcct gaggttcttt
     2161 tactgatgtg ccgcccttcc acctcctcaa gtggtgactt tgtgtgccct ccccctcctt
     2221 tgtgtattcc ttctcaatgc tttccttggt gttaacctta ataaaaaggc gtcatctccc
     2281 ctc
//
