LOCUS       NM_001039374            1716 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 183 (CCDC183), mRNA.
ACCESSION   NM_001039374
VERSION     NM_001039374.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1716)
  AUTHORS   Casabonne,D., Reina,O., Benavente,Y., Becker,N., Maynadie,M.,
            Foretova,L., Cocco,P., Gonzalez-Neira,A., Nieters,A., Boffetta,P.,
            Middeldorp,J.M. and de Sanjose,S.
  TITLE     Single nucleotide polymorphisms of matrix metalloproteinase 9
            (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus
            in chronic lymphocytic leukemia: results from the European
            case-control study EpiLymph
  JOURNAL   Haematologica 96 (2), 323-327 (2011)
   PUBMED   21048031
  REMARK    GeneRIF: Observational study of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB446839.1, BC137318.1, DA235138.1, BC007542.1 and AW572474.1.
            
            On May 17, 2019 this sequence version replaced NM_001039374.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC137318.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000338005.7/ ENSP00000338013.6
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                DB446839.1         1-25
            26-1083             BC137318.1         1-1058
            1084-1084           DA235138.1         447-447
            1085-1321           BC137318.1         1060-1296
            1322-1322           BC007542.1         475-475
            1323-1696           BC137318.1         1298-1671
            1697-1716           AW572474.1         12-31               c
FEATURES             Location/Qualifiers
     source          1..1716
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.3"
     gene            1..1716
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /note="coiled-coil domain containing 183"
                     /db_xref="GeneID:84960"
                     /db_xref="HGNC:HGNC:28236"
                     /db_xref="MIM:615955"
     exon            1..130
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1665
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 183"
                     /protein_id="NP_001034463.4"
                     /db_xref="CCDS:CCDS43906.1"
                     /db_xref="GeneID:84960"
                     /db_xref="HGNC:HGNC:28236"
                     /db_xref="MIM:615955"
                     /translation="MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKAT
                     LALLRSNIRRGAQDWALAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFD
                     RVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMI
                     KIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMIT
                     DEVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLM
                     STETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLEL
                     QMEDCEEWRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLA
                     HSNMTKGQELLLTIQMGIDNLYVRLMGINLPATQREVVLSNTLDLNSKLAYCEGKLTY
                     LADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYV
                     PSRAEIKRQAQRLIEGKLKAAKKKKK"
     exon            131..252
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            253..330
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            331..498
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            499..603
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            604..726
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            727..852
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            853..907
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1008
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1169
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1338
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1449
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1546
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..1716
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1698..1703
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /note="hexamer: AATAAA"
     polyA_site      1716
                     /gene="CCDC183"
                     /gene_synonym="bA216L13.7; KIAA1984; PARF"
                     /note="major polyA site"
ORIGIN      
        1 aagctgagcc cagggaggct ttgaggtaca cagggtccct tggggggcct gagagcagcc
       61 atgaggaggc acagtgagac agatgtggaa gagcagaccc aggagctgaa gaccatcact
      121 cagctccagg agcagtgtcg ggcactccag atccaagggg tgaaagagaa tatggaccag
      181 aacaaggcca cgctggccct cctgcgcagc aacatccgcc gcggggccca ggactgggct
      241 ttggccaaga agtatgacca gtggaccatc tccaaggcct gcgggaaaaa cttgcctttg
      301 cgactggcgc actgccgcag caccatggag gtggtgcggg agaagctgcg caagtacgtc
      361 ttcgaccgcg tgaacatgca caacctactg atccacctgg tgcggcggcg cgggcagaag
      421 ctggagagca tgcagctgga gctggacagc ctgcggagcc agcccgacgc cagcaaggag
      481 gagctgcggc tgctgcagat catccgccag ctggagaaca acatcgagaa gacaatgatc
      541 aagatcatca ccagccagaa catccacctg ctgtatttgg acctgctgga ttatctgaag
      601 acagtgctgg caggataccc cattgagctg gacaagctgc agaacctcgt ggtcaactac
      661 tgctcagagc tgtcggatat gaagatcatg tcccaagatg ccatgatgat cacggatgag
      721 gtcaagagga acatgaggca aagggaggcg tccttcatcg aggagcgccg ggcaagggag
      781 aaccggctca accagcagaa gaagctgatc gacaagatcc acacgaagga gaccagcgag
      841 aagtaccgcc ggggccagat ggacttggac ttcccctcga acctgatgag cacggagacc
      901 ctgaaattga ggagaaaaga gacctccaca gcagaaatgg aataccagtc gggcgtgact
      961 gctgtggtgg agaaggtcaa gagtgctgta cggtgctctc acgtctggga catcactagc
     1021 cgcttcctgg cccagaggaa cacggaggag aacctggagc tgcagatgga ggactgtgag
     1081 gagtggcggg tgcagctgaa ggccctggtg aagcagctgg agctggagga ggccgtgctc
     1141 aagttccgcc agaagcctag ctccatcagc ttcaagtccg ttgagaagaa aatgacagac
     1201 atgctaaaag aggaagaaga gaggctccag ctggcgcaca gcaacatgac caagggccag
     1261 gagctgctgc tgaccatcca gatgggcatc gacaacctct atgtccggct gatgggcatt
     1321 aacttgcctg cgacccagag agaagtggtg ctctccaaca ccctcgattt gaacagcaag
     1381 ctggcgtact gcgaggggaa gctcacgtac ctggctgaca gagtgcagat ggtgtccagg
     1441 accgaggagg gcgacacaaa ggtgagggac accctggagt cctcgactct gatggagaag
     1501 tacaacacca ggatcagctt tgagaaccgg gaggaggata tgatcgacac cttccagttc
     1561 cccgacatgg accacagcta cgtcccttcg cgcgccgaga tcaagaggca ggcgcagcgg
     1621 ctaatcgagg ggaagctcaa ggcggccaag aaaaagaaga agtagccccg ccgccccgct
     1681 ccctgctttg ctacacaaat aaacattttt ccagga
//
