LOCUS       NM_001195637             848 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens coiled-coil domain containing 179 (CCDC179), mRNA.
ACCESSION   NM_001195637
VERSION     NM_001195637.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006299.1 and AI651461.1.
            
            On May 17, 2019 this sequence version replaced NM_001195637.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HY018043.1, HY242599.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000532798.3/ ENSP00000457511.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                AC006299.1         67096-67143
            49-138              AI651461.1         276-365             c
            139-139             AC006299.1         68114-68114
            140-378             AI651461.1         36-274              c
            379-848             AC006299.1         80179-80648
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p14.3"
     gene            1..848
                     /gene="CCDC179"
                     /note="coiled-coil domain containing 179"
                     /db_xref="GeneID:100500938"
                     /db_xref="HGNC:HGNC:44653"
     exon            1..98
                     /gene="CCDC179"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..260
                     /gene="CCDC179"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 179"
                     /protein_id="NP_001182566.1"
                     /db_xref="CCDS:CCDS58127.1"
                     /db_xref="GeneID:100500938"
                     /db_xref="HGNC:HGNC:44653"
                     /translation="MCLYCWDIEPSQVNPEGPRQHHPSEVTERQLANKRIQNMQHLKK
                     EKRRLNKRFSRPSPIPEPGLLWSS"
     exon            99..143
                     /gene="CCDC179"
                     /inference="alignment:Splign:2.1.0"
     exon            144..248
                     /gene="CCDC179"
                     /inference="alignment:Splign:2.1.0"
     exon            249..848
                     /gene="CCDC179"
                     /inference="alignment:Splign:2.1.0"
     regulatory      385..390
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC179"
                     /note="hexamer: AATAAA"
     polyA_site      415
                     /gene="CCDC179"
                     /note="major polyA site"
ORIGIN      
        1 atttggtcca ggacaggcag taggcgtcag ggggcgccct aaggctccac ggcatgtgcc
       61 tgtattgctg ggacatcgag ccttcccaag tcaaccctga aggaccaaga caacatcatc
      121 cttcagaggt cactgagcgg cagcttgcaa ataaacgtat tcagaatatg caacacctaa
      181 agaaagagaa gaggagactg aataaaaggt tttcaaggcc ttctcctatt ccagaaccag
      241 gactcctatg gtcatcttga taaagcagga gtctatttga aggaaaccat gctccagaca
      301 gaaatatgtg gattgtgaac atcaagtgac atatcatgaa ttgatcatcc acaaaataaa
      361 tgcaatactc caccatttcg gaaaaataaa cacagtgcaa gtatttaata tccaagctac
      421 aggctctaga attttattaa atgccatctc tcactaccat atttttcttt cctgtggtaa
      481 acttgaaatt tgctgctttt caacaaataa taatgaatat gtataggtag acttttgaaa
      541 aatattattc tcatttaaat ttttgcaaat gttttatgac atatttagat gtttagaagt
      601 atgttataat aatagaacac cagatttcct ctgctgtata tttataatga cttccattta
      661 aacaaaatgt ttaaatactt taaacagtcc taggagactg ttattataac taactcctgt
      721 attttgtgtt gctattgcag ataagccata gtgtaattaa aatttccatt taaggtaaaa
      781 tttgaatatt gaattaaaat tttactttta ggtatgaaat aaattataat tattgctgac
      841 tctctaaa
//
