LOCUS       NM_001198910            2600 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens CCDC169-SOHLH2 readthrough (CCDC169-SOHLH2), mRNA.
ACCESSION   NM_001198910
VERSION     NM_001198910.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Benjamin,D.J., Cesarini,D., van der Loos,M.J., Dawes,C.T.,
            Koellinger,P.D., Magnusson,P.K., Chabris,C.F., Conley,D.,
            Laibson,D., Johannesson,M. and Visscher,P.M.
  TITLE     The genetic architecture of economic and political preferences
  JOURNAL   Proc Natl Acad Sci U S A 109 (21), 8026-8031 (2012)
   PUBMED   22566634
REFERENCE   2  (bases 1 to 2600)
  AUTHORS   Prakash,T., Sharma,V.K., Adati,N., Ozawa,R., Kumar,N., Nishida,Y.,
            Fujikake,T., Takeda,T. and Taylor,T.D.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS One 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK301863.1 and AL160392.12.
            
            On Jun 2, 2019 this sequence version replaced NM_001198910.1.
            
            Summary: This locus represents naturally occurring read-through
            transcription between the neighboring C13orf38 (chromosome 13 open
            reading frame 38) and SOHLH2 (spermatogenesis and oogenesis
            specific basic helix-loop-helix 2) genes. The read-through
            transcript encodes a fusion protein that shares sequence identity
            with the products of each individual gene. [provided by RefSeq, Nov
            2010].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK301863.1, SRR18074969.565579.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 54937, 728591
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2023              AK301863.1         29-2051
            2024-2600           AL160392.12        50372-50948         c
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q13.3"
     gene            1..2600
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /note="CCDC169-SOHLH2 readthrough"
                     /db_xref="GeneID:100526761"
                     /db_xref="HGNC:HGNC:38866"
     exon            1..178
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            179..289
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     CDS             275..1783
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /note="C13orf38-SOHLH2 readthrough; Spermatogenesis- and
                     oogenesis-specific basic helix-loop-helix-containing
                     protein 2"
                     /codon_start=1
                     /product="CCDC169-SOHLH2 protein"
                     /protein_id="NP_001185839.1"
                     /db_xref="GeneID:100526761"
                     /db_xref="HGNC:HGNC:38866"
                     /translation="METLQESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKIN
                     NERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTLLLKEELDPLKAKIDILLVG
                     DVTVGYLADTVQKLFANIAEVTITISDTKEAAALLDDCIFNMVLLKVPSSLSAEELEA
                     IKLIRFGKKKNTHSLFVFIIPENFKGCISGHGMDIALTEPLTMEKMSNVVKYWTTCPS
                     NTVKTENATGPEELGLPLQRSYSEHLGYFPTDLFACSESLRNGNGLELNASLSEFEKN
                     KKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGRKNDAASVLEATVDYVKYIREKIS
                     PAVMAQITEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMSTYSPERGLQFLTNTC
                     WNGCSTPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALSLNSLHTVRYYSKVTP
                     SYDATAVTNQNISIHLPSAMPPVSKLLPRHCTSGLGQTCTTHPNCLQQFWAY"
     exon            290..388
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            389..442
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            443..519
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            520..553
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            554..768
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            769..830
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            831..935
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1035
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1146
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1294
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1386
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1505
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1506..1762
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..2600
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2575..2580
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /note="hexamer: AATAAA"
     polyA_site      2600
                     /gene="CCDC169-SOHLH2"
                     /gene_synonym="C13orf38-SOHLH2; SOHLH2; TEB1"
                     /note="major polyA site"
ORIGIN      
        1 accgcctcgt gccgtactgg cttctgggtg gcccttaatg tcttgtgctc taaggtgctg
       61 aggggaaaga cgcgggaggt ctctggcctg acactatgaa ggaagagaga aactacaact
      121 tcgacggtgt gagcaccaac cgcctgaaac agcagttgct ggaagaagtc cgcaagaagt
      181 agtgaatgga aaacccgtta tgagacacaa cttgaattaa atgatgaact agaaaagcaa
      241 attgtttatc tcaaggagaa agtggaaaaa atccatggaa actcttcagg aatccttaaa
      301 cacattactt aaacagctag aagaagaaaa gaagactctt gaaagtcaag tgaaatacta
      361 tgcacttaaa ctggaacaag aatcaaaggc ttaccagaag atcaacaatg aacgccgtac
      421 atacctagct gaaatgtctc agggttctgg tttacatcaa gtttctaaaa ggcaacaggt
      481 ggatcaactg cctaggatgc aagagaatct agtgaaaacc ctcctcttaa aagaagaatt
      541 ggacccttta aaggcaaaaa tagacatctt attagttgga gatgtcactg tgggctacct
      601 ggctgatact gtacagaaac tatttgcaaa catagcagaa gtcaccatca ccatcagtga
      661 cacgaaggag gcagcagcgc ttttggatga ttgcatattc aacatggttc tcttgaaggt
      721 gccttcttca ctaagtgccg aggagctgga agccatcaag ttaattagat ttggcaaaaa
      781 gaaaaataca cattcactgt ttgtttttat aatccctgaa aattttaaag gttgtatttc
      841 agggcatgga atggatattg ctttaactga accactgaca atggaaaaaa tgagtaatgt
      901 ggtaaaatac tggacaacat gtccctcaaa cactgttaag actgaaaacg caactgggcc
      961 tgaagaactt ggattgcccc tgcagaggtc ctacagcgaa cacctgggat attttcctac
     1021 tgatctattt gcctgctctg aatctttaag gaatggcaat gggcttgaat taaatgcttc
     1081 gttgtcagag ttcgagaaaa acaaaaagat ctctcttctt cattcaagca aggaaaaact
     1141 aagaagggaa agaatcaaat attgctgtga gcagctgcgt actctcttgc cgtatgtaaa
     1201 agggagaaag aatgatgcgg cttcagttct tgaggcaaca gttgattatg tgaaatatat
     1261 ccgggagaaa atctctccag ccgttatggc ccagattaca gaagcacttc agagcaacat
     1321 gaggttttgt aagaaacaac aaacacccat tgagctgtct ctcccaggca ctgtcatggc
     1381 acagcgggaa aacagtgtga tgagcactta ctcccctgag agagggctcc aattcctgac
     1441 taatacgtgc tggaatgggt gctccactcc tgatgcagag agctccttgg atgaagctgt
     1501 gagagttcca tcaagctccg cctcagagaa tgctattggt gatccatata aaactcacat
     1561 ttccagtgca gcgctgtctc tgaattcctt gcatactgtc agatattatt ctaaagtcac
     1621 cccttcctac gatgcaactg ctgtaacaaa tcagaacatt tcaattcatt taccttcagc
     1681 catgcccccg gtctcaaagc ttctccctcg gcactgcact tctgggttgg gccagacgtg
     1741 cactacacat cccaactgtc tgcaacagtt ttgggcgtat taaaagcaca tgtttgaaat
     1801 tcacactctc aaccacctac tgggcgcagt ttgacaatct aggaaaagtg gaacaaagaa
     1861 tgattttgaa agctccaccc aaagacctaa tatcaaaaga gttggcatgg tttggcttct
     1921 gataaatgca ctcaaagctt ctgcagatag aaagaccagc agcgaaaaag ctggccacac
     1981 actgtcactc atcttcatac acacttggat ccccgccagc cagagagcta caagaacaaa
     2041 tggcctcagt gacctacact ctcttttctc aaaaaatatt ccacaattta tgaaaaaagc
     2101 atgctataag gaagatccat gtagacacga taaaatgatt agattgggaa ggtgtgttga
     2161 taccttgtgt cactgagtac agatattaca acttgattct tatttttagt atccctgtga
     2221 attactgtca ctcatttcta ggtggtcttt tccttatttg acattttaga gagtttcctt
     2281 cttcattcac catccaaact aagatatgca gagagatgct gaaagagggg tttacctcct
     2341 cacttgacaa ctaatgaata aattgatgtg tgcttttgca tttcacaatc ccttgagtga
     2401 aacgatggct aataggtaaa tatttctttc tggaccttaa gttacagact agcaggtttt
     2461 ttgtttttca tctcttcctc cctatgggta ttagaaagga cagttgaaaa taagggggaa
     2521 aaaggtttgt tttatatttc actgaattgt tcttatatgt aagttttatt attaaataaa
     2581 atactcagtt ttcaccctga
//
