LOCUS       NM_001144981            1158 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens coiled-coil domain containing 169 (CCDC169),
            transcript variant 1, mRNA.
ACCESSION   NM_001144981 XM_001130109 XM_001133689 XM_001719885
VERSION     NM_001144981.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Venter,J.C., Adams,M.D., Myers,E.W., Li,P.W., Mural,R.J.,
            Sutton,G.G., Smith,H.O., Yandell,M., Evans,C.A., Holt,R.A.,
            Gocayne,J.D., Amanatides,P., Ballew,R.M., Huson,D.H., Wortman,J.R.,
            Zhang,Q., Kodira,C.D., Zheng,X.H., Chen,L., Skupski,M.,
            Subramanian,G., Thomas,P.D., Zhang,J., Gabor Miklos,G.L.,
            Nelson,C., Broder,S., Clark,A.G., Nadeau,J., McKusick,V.A.,
            Zinder,N., Levine,A.J., Roberts,R.J., Simon,M., Slayman,C.,
            Hunkapiller,M., Bolanos,R., Delcher,A., Dew,I., Fasulo,D.,
            Flanigan,M., Florea,L., Halpern,A., Hannenhalli,S., Kravitz,S.,
            Levy,S., Mobarry,C., Reinert,K., Remington,K., Abu-Threideh,J.,
            Beasley,E., Biddick,K., Bonazzi,V., Brandon,R., Cargill,M.,
            Chandramouliswaran,I., Charlab,R., Chaturvedi,K., Deng,Z., Di
            Francesco,V., Dunn,P., Eilbeck,K., Evangelista,C., Gabrielian,A.E.,
            Gan,W., Ge,W., Gong,F., Gu,Z., Guan,P., Heiman,T.J., Higgins,M.E.,
            Ji,R.R., Ke,Z., Ketchum,K.A., Lai,Z., Lei,Y., Li,Z., Li,J.,
            Liang,Y., Lin,X., Lu,F., Merkulov,G.V., Milshina,N., Moore,H.M.,
            Naik,A.K., Narayan,V.A., Neelam,B., Nusskern,D., Rusch,D.B.,
            Salzberg,S., Shao,W., Shue,B., Sun,J., Wang,Z., Wang,A., Wang,X.,
            Wang,J., Wei,M., Wides,R., Xiao,C., Yan,C., Yao,A., Ye,J., Zhan,M.,
            Zhang,W., Zhang,H., Zhao,Q., Zheng,L., Zhong,F., Zhong,W., Zhu,S.,
            Zhao,S., Gilbert,D., Baumhueter,S., Spier,G., Carter,C.,
            Cravchik,A., Woodage,T., Ali,F., An,H., Awe,A., Baldwin,D.,
            Baden,H., Barnstead,M., Barrow,I., Beeson,K., Busam,D., Carver,A.,
            Center,A., Cheng,M.L., Curry,L., Danaher,S., Davenport,L.,
            Desilets,R., Dietz,S., Dodson,K., Doup,L., Ferriera,S., Garg,N.,
            Gluecksmann,A., Hart,B., Haynes,J., Haynes,C., Heiner,C.,
            Hladun,S., Hostin,D., Houck,J., Howland,T., Ibegwam,C., Johnson,J.,
            Kalush,F., Kline,L., Koduru,S., Love,A., Mann,F., May,D.,
            McCawley,S., McIntosh,T., McMullen,I., Moy,M., Moy,L., Murphy,B.,
            Nelson,K., Pfannkoch,C., Pratts,E., Puri,V., Qureshi,H.,
            Reardon,M., Rodriguez,R., Rogers,Y.H., Romblad,D., Ruhfel,B.,
            Scott,R., Sitter,C., Smallwood,M., Stewart,E., Strong,R., Suh,E.,
            Thomas,R., Tint,N.N., Tse,S., Vech,C., Wang,G., Wetter,J.,
            Williams,S., Williams,M., Windsor,S., Winn-Deen,E., Wolfe,K.,
            Zaveri,J., Zaveri,K., Abril,J.F., Guigo,R., Campbell,M.J.,
            Sjolander,K.V., Karlak,B., Kejariwal,A., Mi,H., Lazareva,B.,
            Hatton,T., Narechania,A., Diemer,K., Muruganujan,A., Guo,N.,
            Sato,S., Bafna,V., Istrail,S., Lippert,R., Schwartz,R., Walenz,B.,
            Yooseph,S., Allen,D., Basu,A., Baxendale,J., Blick,L., Caminha,M.,
            Carnes-Stine,J., Caulk,P., Chiang,Y.H., Coyne,M., Dahlke,C.,
            Deslattes Mays,A., Dombroski,M., Donnelly,M., Ely,D., Esparham,S.,
            Fosler,C., Gire,H., Glanowski,S., Glasser,K., Glodek,A.,
            Gorokhov,M., Graham,K., Gropman,B., Harris,M., Heil,J.,
            Henderson,S., Hoover,J., Jennings,D., Jordan,C., Jordan,J.,
            Kasha,J., Kagan,L., Kraft,C., Levitsky,A., Lewis,M., Liu,X.,
            Lopez,J., Ma,D., Majoros,W., McDaniel,J., Murphy,S., Newman,M.,
            Nguyen,T., Nguyen,N., Nodell,M., Pan,S., Peck,J., Peterson,M.,
            Rowe,W., Sanders,R., Scott,J., Simpson,M., Smith,T., Sprague,A.,
            Stockwell,T., Turner,R., Venter,E., Wang,M., Wen,M., Wu,D., Wu,M.,
            Xia,A., Zandieh,A. and Zhu,X.
  TITLE     The sequence of the human genome
  JOURNAL   Science 291 (5507), 1304-1351 (2001)
   PUBMED   11181995
  REMARK    Erratum:[Science 2001 Jun 5;292(5523):1838]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB454585.1, DN999189.1 and AK308999.1.
            
            On May 17, 2019 this sequence version replaced NM_001144981.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.205020.1,
                                           SRR5189661.10601.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000239859.8/ ENSP00000239859.7
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                DB454585.1         43-52
            11-590              DN999189.1         9-588
            591-1158            AK308999.1         521-1088
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q13.3"
     gene            1..1158
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /note="coiled-coil domain containing 169"
                     /db_xref="GeneID:728591"
                     /db_xref="HGNC:HGNC:34361"
     exon            1..178
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..740
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /note="isoform a is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 169; RP11-251J8.1"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 169
                     isoform a"
                     /protein_id="NP_001138453.1"
                     /db_xref="CCDS:CCDS45028.1"
                     /db_xref="GeneID:728591"
                     /db_xref="HGNC:HGNC:34361"
                     /translation="MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITE
                     LEAKLNTDNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYER
                     MPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGL
                     HQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP"
     exon            179..258
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            259..369
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            370..410
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            411..509
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            510..563
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            564..640
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            641..1158
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /inference="alignment:Splign:2.1.0"
     regulatory      833..838
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /note="hexamer: AATAAA"
     regulatory      838..843
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /note="hexamer: AATAGA"
     polyA_site      855
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
                     /note="major polyA site"
     polyA_site      867
                     /gene="CCDC169"
                     /gene_synonym="C13orf38"
ORIGIN      
        1 accgcctcgt gccgtactgg cttctgggtg gcccttaatg tcttgtgctc taaggtgctg
       61 aggggaaaga cgcgggaggt ctctggcctg acactatgaa ggaagagaga aactacaact
      121 tcgacggtgt gagcaccaac cgcctgaaac agcagttgct ggaagaagtc cgcaagaagg
      181 atgcagtgca actctcaata tttgaactaa gacacaagat tacggaactg gaagccaaac
      241 tcaatactga caatgaaggt agtgaatgga aaacccgtta tgagacacaa cttgaattaa
      301 atgatgaact agaaaagcaa attgtttatc tcaaggagaa agtggaaaaa atccatggaa
      361 actcttcaga tagactatct tctattcgtg tctatgaacg aatgccagtg gaatccttaa
      421 acacattact taaacagcta gaagaagaaa agaagactct tgaaagtcaa gtgaaatact
      481 atgcacttaa actggaacaa gaatcaaagg cttaccagaa gatcaacaat gaacgccgta
      541 catacctagc tgaaatgtct cagggttctg gtttacatca agtttctaaa aggcaacagg
      601 tggatcaact gcctaggatg caagagaatc tagtgaaaac tggaagatat aatccagcta
      661 agcagaagac agtgagtgcc aagagaggac cagtaaaaaa gattacaaga ccaaaccatc
      721 ttccagaact ccatccatga ttccagaact ggatggattt ctatttcttc cttttttttt
      781 ccatttataa tattcaagtt ataaagttaa tggtcagcac atttcttcag ggaataaaat
      841 agataagaac tgccacattt ttctttagtt ccttttccag acgtgtgttc ctttgtctgc
      901 ataaaagtaa ttttctccag tgaccctaaa ctatgtaata gaagtgcttg agagttttaa
      961 aatatcctag ggaatctgaa ggctggcatc attacacttg ctttcaataa tatacccatg
     1021 atctgctctg atagtaacgt tgctattcta tttggtttct agttgactgt tagcaaaaag
     1081 tgtgtattca taaaaccttt ttgccatttt gggctggatc ttgctcagtt ttttaaattg
     1141 caggtttaaa caaagccg
//
