LOCUS       NM_001146197           21470 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens coiled-coil domain containing 168 (CCDC168), mRNA.
ACCESSION   NM_001146197 XM_001714647
VERSION     NM_001146197.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 21470)
  AUTHORS   Woolfson,D.N.
  TITLE     The design of coiled-coil structures and assemblies
  JOURNAL   Adv Protein Chem 70, 79-112 (2005)
   PUBMED   15837514
  REMARK    Review article
REFERENCE   2  (bases 1 to 21470)
  AUTHORS   Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
            Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
            Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
            Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
            Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
            Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
            Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
            Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
            Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
            French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
            Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
            Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
            Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
            Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
            Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
            McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
            Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
            Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
            Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
            Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
            Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
            Bentley,D.R., Rogers,J. and Ross,M.T.
  TITLE     The DNA sequence and analysis of human chromosome 13
  JOURNAL   Nature 428 (6982), 522-528 (2004)
   PUBMED   15057823
REFERENCE   3  (bases 1 to 21470)
  AUTHORS   Burkhard,P., Stetefeld,J. and Strelkov,S.V.
  TITLE     Coiled coils: a highly versatile protein folding motif
  JOURNAL   Trends Cell Biol 11 (2), 82-88 (2001)
   PUBMED   11166216
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL157769.12 and AL833908.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_001146197.2.
            
            Sequence Note: The RefSeq transcript and protein are predicted from
            genomic sequence based on conservation of a very long ORF in the
            genomes of several mammals including human, mouse, and dog. The
            precise splice pattern has not been experimentally determined.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU853215.1, DB098526.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000322527.4/ ENSP00000320232.3
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-371               AL157769.12        43421-43791         c
            372-405             AL157769.12        43262-43295         c
            406-448             AL157769.12        43129-43171         c
            449-21469           AL157769.12        14087-35107         c
            21470-21470         AL833908.1         1407-1407
FEATURES             Location/Qualifiers
     source          1..21470
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q33.1"
     gene            1..21470
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /note="coiled-coil domain containing 168"
                     /db_xref="GeneID:643677"
                     /db_xref="HGNC:HGNC:26851"
     exon            1..371
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /inference="alignment:Splign:2.1.0"
     CDS             141..21386
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /note="coiled-coil domain-containing protein 168"
                     /codon_start=1
                     /product="leucine-rich repeat transmembrane protein
                     CCDC168"
                     /protein_id="NP_001139669.1"
                     /db_xref="CCDS:CCDS73596.1"
                     /db_xref="GeneID:643677"
                     /db_xref="HGNC:HGNC:26851"
                     /translation="MSKQYYSFKKGVGSGLEDNTFMTLWDFLESWIIQNDWVAIFFII
                     LLGIIFEIILMKACASFWKKPTLPEKGSSDVQETEDSCPKSRKLAPENWSVINSSSGE
                     RVGTFLEKRITSSLTSEEKECNFEDRILFSREILWSGTSESEDQVSPSSESHVPSSNG
                     ISSSLPLFYSEVEETCLSHTEHPDREYETIQFSSKKLFSMMKTNKNKNSGFSSDLSFS
                     ASRFTVENEDLDVAPCPLAHLFLSRDQVRLLEENVRNQIPSKPKTKLGSRTTYQCSRS
                     QESLNQNQPSVGMVISVQAQDSFPGQNAFQNQGLYEVQFTSQAQYINHNQESIKSQPE
                     SKASNFAQPEDVMKKPFSSSTQDSFQSQDLDRNQHFVEVPSIVEAKYSVKGLESDEHL
                     GEDQHCVWFIDSNKVKYSIKGQDTIFKNAEFLVLTLNPNLVTEDMPQLRSVKAQGQQQ
                     IVSSELNQDSVYSSVPLLSTIKGQKNRRKTPDSKSKLSLNVPSLKAKKTPTSQVFQIT
                     VCHTLKNRNELGCKNNTEKKELHERKDISDIALHLISVSKLILPYVKNYSRKQLVKVM
                     PGLIKCGHFLQKQNKSPDTEKINYAGPLEETGISDITKKEKEYDKENKRLKNISPKML
                     PQLEQSFMVNTVQLKAPCLLVETNGKSKESLKDSITQAKGIGITEFHVLNSKKPFDLH
                     IPKHKTSLEEAISKPMQKLVSSPEMESNNRMKIQEDLQSSENSHLQLSNGEELPTSTP
                     KTQRCFPRENTQKQKDFLELVLELSNVGLLISPGSKMHKSSEELEAIKIQVNTESVNL
                     KESKPLILNVTEDSDLRESEELECNTGSNITNMHQDKETSDAFHSATYTTISQLPDTE
                     THSISKAKADTLRIIRLSHSASKQEKLPDEKETQNAEYIDKSCTFKKPQQCDRKEQEK
                     EANSELTQGFRFSIHLKQKPKYVKFQMEQISSGSSKAPNKEQEVQPQTLSTQTILENS
                     PCPMMDPFQVEKVKQSTDRPTDRESAGDPKNPLTMPENLPVGELLIETTEYSVPFGGN
                     LQKTTDSHIAEEKEDVKRYLPAVALGSFNNHLLTLPYFKRQEIKKKLSETKSVLSVKY
                     VIMKVKKPAISLMPYINICGTSNHRKKMGGNFEIIIKQILQDKIAAGMLLNVIYPPMS
                     ILPNTRMYSRLNAENHSHIKLVQEESQIEREEKYPYFINEGNESQNTLDAKLQDEVKG
                     VKETLPKAVLHDSCNLGLDAHLEKEIKTEKEMHQPIPFTETIIESVVSPIMELSHAEN
                     VKSTQKTQTDCKCTADSETPSPISGKSLIGDPLNQTRESYIPSNGSDTREMGYCFAEE
                     KTEIPKDLPATSPETFNYCTPVLSCSKVMKKRVTFALTTSTAKPKCVNTKAVKPSISE
                     TVSVTSHRKKSELDFKTKFKKINQTKGLVPECLNTLCSPMHSRLQREFCLPASQLKQG
                     ETADKTYTDVFAKNSISHDREEKLQDGKEEEHKVLLEAAPQLSQHLGSEAGQMKEIHL
                     ESDPVLNCLTLELHINGQRLQHQTGFEQTTLETSLQMGPLEAEELQKANETENDIKVL
                     GGPKIPPPKALQALENSDGLILNAYQKDNELVKSDEELNQPGSTNIQVQPQTHFTQTI
                     LKSTSCPTLDQFPFEKVESHVRFSPLKSGEAKVDEIIFYAREGGISSDSSHQKEQAGG
                     TEKKETAIFGSCMPALSTPKTTRNLKQFSDMKTLVNPKCGIIKAKKPSISYMLNIRAG
                     AGPKRRKELSCNLTTKMKELHQGKKGVDETYAFLTMTPDINKYSKVETEKDTLREKRL
                     SSTQVKQDTSPHEDSITSRDIKETLLQDEEQEERKQEALLKVIPQHLQHFMFRSGQGK
                     DLDFHKLENQGSRKILFVTKQDVPQQLQPAEPIQREETKKCLQTQNGTICTVNSKLLP
                     LKSEDSVNGEVLTGAIKRGVPTDRKCMGEQHNSGKGEKAEFNKDLQATVLELQKSPHG
                     GEAQKANLTDMESGSSNAMNMNVQHEREDKNIQKMLTESVPCYSQHLRFSTHQMKDPD
                     PCKSGSEPKSPEGRSWNLSHIVQKTKQETHFRETVLEPISGYMMKQSPHMQEGIKCME
                     GLKTSFPKTGKSKIGSIPRDTPWDENPRRKWDSSISEKTAWNQKNLQTVLKPLDFSSL
                     MSSEYESRSYTLEFIGKKSMSPKCVTLKAKQLRILQLFNIIRYSTENHRKKKQHRFKY
                     KMKGKQWYTSIGEALLSATEYAKSTTSKSMIDKLLYNTAARCILSNRTRRQNLDGHIT
                     EEKEEVQENVAAIFLGLLDFFMPVLSDSKNQRNTAQLSEKEIIFNAKCLTMKEKKSSI
                     SQIHKINRESTRKHRKKCKSYLKTVSNRKCQENHGHITEEEEEVQENSPATFLGPLDF
                     FMPVLSDSKNQINTIQLSERKIILNPKCLTMKEKKPPISQIHKISGQFTTKHRKKLES
                     NLKTKLKAMWQGENVADTFPNTTSFTPDSSDIKRQSGFQTEIDMRISGLSHTQPTQIE
                     SLAEGIARYSDPIDKRRTSNLVKGAKLHDRESGEEKQEHLTEMDPFYAENFMANTYLR
                     KDRHLGKSEDVLLGETFFSKSQIYKGNSEKNVKIEKNKNGKESLKVGLARMEKSDNCA
                     ELSEATDDAISNKYDKQNIGHSVLKENAFCNLAAIVPDSVGRHSPASEEMKRQNGRLK
                     MADRSSPQGRPLQAKQSAVSQSPDTAGYAVVSNNKEQKQNFKAQKTEAEVDLIDQEAK
                     INVAEEFNPESVFFSKIHPLQIENKKEFKTADWKTRADPKTFALPKKQQELCVSGTIW
                     SYPNPYTSISPKIIRHKDKAKTADVESTMHTKQIKLKAKRITVSQLLEYGTASNKKEL
                     RGNIQQQKSFQLSKNAVHRVLKAVYDSGYCVSSIKKLTEVKMEKDKPKDRTCILPQPK
                     LEKPLKEMQRSLSGCTDMSSILRKQEQDIREKEQKHQSISEDISQYYIGPLRISSQQI
                     NYSSFDAPRIRTDEELEFLIAQRAKEKDVGIAKHSVSIPWEREGSKRLDIPLNSKGQN
                     IFFTELDTSQQKTCQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYIN
                     RKISSHVLGKEGLKETDIFVGSKGQKFLCTNSEVQHKVPAEQKEQVNPDHVPESILDS
                     ESFLSKDPLHLKQAVNTARKENVTISESFNENLWGKEQSKLDITLKSNRQKMDFSKKL
                     RMKHLSNYYQNKENILESVLPCILHQLYIENPKKEGSAEEIMSSKVLSPMVEKASHEV
                     GIPVDQPPCSEGIHLNIKGRKEHPQESTHEAFPASVSHSLMDVLQIKSPKVKKALKAI
                     NSLGYLTSNTKGIGLLFPRQAEKEEKYTYKALPKPASHSKTDLFQFNASMQQEKLDAM
                     DIPHYDYLTSQTREAVKQMDVIVGYTQNSKKRQDLLKTGQKWQYLPISYENFWEHISC
                     PQKYPCLLQHLMPQEKEALSEGGNLSSRTPGLDLFSADQLSTITKNRLEWIVPLISPR
                     QMKKQDSMLPLGSYHKTIKYASLLFPKGMKSSDGVQVFDLISNNSSPKLRLGKKIETQ
                     KANEKVQKEVCLPITLHSLSASMPILQESKGQKDSVEQVIRKGVICHKRRTSKWKKSV
                     FSHILNTSDCGASSNRLEMQWNMTDKMVNVKHRMSEIDLVAAKICESILSLPHFKLNK
                     ETIDGVISSNVKSTKQHISQGKNDRVKAMDMKRIKSPNIILKPRKSSLSHILSIKEFP
                     LLLDIIKQEGKMQEGKGKSSMKLTNLCTSLPSLSHSNSNSRTKAGKDKSGTLKGCLPP
                     LKLQASSNARRVSSAESINRDSLSNVIESKCFPQKKKEDRENIVDVKDVMGLKCITLK
                     GKKSLFRHLLHGKEPQRSNKKLEKMTQEDESNLNVVQNKLCASILSPPHLEWNPRIKE
                     VYMRGITRFCLSSSTQQELSDTMEKCEQPIDDSLSSIEKAKHMPQKDKDRVEKALEKI
                     MHSKRIALEVKQPSIFQELELNIKEKGGKIQEDKEVEIWSKPFASISFLPYSKVGTIE
                     GEEAMRIKMRSSFSQPNLQESSDTEKTAYEKCISDNISNSVKKALESILQKEQRQKME
                     KIRALKKMKSSISQGIQLDIKEQEKRIEHIKGEPSVLLTNACASIPSPSHLQLDTRRE
                     KAEYVTEITRYYLPELSHQKSSEAGEKADGVASKGDITIKVQKAKDYMQQKEDDEVKI
                     SAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRG
                     AGQEKVDREDKEQGKMDHEVEEQQKADGVGIEQGKMDGDKNEQERVLFLYLPSNSSLT
                     HYILDTRIEGEEDQQGIIRPGILQPRHQKSSETGKKANGVPSEGDSASEVQKAKDYMQ
                     QKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKEDGEGE
                     EQGNRDGETEEQQQADGVGTEQEKRDGHKSKQETVLFLHLPSESSLTCYELNTRKEGE
                     EDLQGIIKSATLQLRQQKSFDAGKIAHTKSFGVDSSNDVKTVQEYKPQKEVDRGKTVS
                     VDYIMQPEGTIFEAEQLSLPHTLNIPGSSGSKTREVLTNIKEKLRHVQERKSELDVFL
                     TIPSLSHCKLDKRTAGKKEEQGVTRSFLPPSWHMESSDTGKLKYTLSYLNDITGDSNR
                     TKYMAQIQKDKANISEKSVMHPEYIAVKAEKSPLSHILKTKELQVNISQQGEKAQEGE
                     VEIVVLLSKTCPFVTSSAFLELDSIKEEEGEPRITRSFMPHLEIQESLPSRQTAPTKP
                     TESLVKKEKQLLPQKEDRVQTVSMHGLMHPNGAVFKAKTSAPPQVFSITEHSPLSKRK
                     EPQWGMKERAGQKQDRTGRPHVILTKTHPFMPSLSHHRFSPSQPKLPISSGAGKSRLA
                     NSNEGISSHKVILKANQQMPYKEAKDRVKIEGREGRILPKRIHLRAEALPLALLCNGK
                     NYSLHIEEQGEGVQESKKEPGVVPRKSASFPPPPFYLNCDTRRNEKEGTLGKTQFSFP
                     PLKIQDSSDSGKKAYTESLHGYTLSNSKGPVQPTAQGEEKGGLRIDMEDKMLPKCTDL
                     KAKQLLLSDILNTKKLQWKSKEQKRKIQEDKNKQVKGLPSINTSLLTPPYLKFDTTEG
                     QENVIRIAKVSLPQSRSKESSDAGRIACPEATHGELSSDVKQLKAHLLQKEEKDREKV
                     ADMTSVLDPNKMYLKAKKSPVLHTHSFSDLQWKTREQEEEKVQKVKSGPGVMLSKSPS
                     RSSPLHLNVNTGFQEESIPILTRPSFPLVKLQVSPDTEGGTCIRPIAGDILIYLQKGK
                     HVSQNKEEDDVQIVSILIFPKHQEEKVQECEGEPGVVLTKSTSLPSLSQLELDKETHL
                     GNEMLRLKRPILRRISHIGETVHRESVVGDIPKDVKNEKQHIPQKEERNQKKIIDMRG
                     TDITLKSKKSPRSCMLHRTELHVNIGGQGRKEHEGQDKPPGMIQRKMCILFSKPLPSN
                     LKLERATHADEERLGGKTSFVLPLMPSALPDTEKTADAEARSGDVRKGKPHRSQKENR
                     HEVKTIDMRFRIHCQEARISPMSHILNAKELVLNINKLEKKVHKDKDEACVVLSRTFL
                     SIPSAPPLYLDSGNKTDKDTPGITGSSCPQRTLHVPSNTQKITNRDSVEGVDKNVVKQ
                     AEQYVPRPEAEQQLTSNFMISVQQRNQPSRVRSEEDLNQLVLNSRDEDIYFTGFGTIR
                     SGKRPEWLFTGKKAQPVKYKTETLTAFLSYPTMDATKMGGLEEDTEIMDNLNHKISPK
                     ASVSLIRKISKELYVTLGTPANSKGFSVSERYAHQQETSSKVSPELAGSCKFDKPKED
                     GQSNDRISKMFSPKVLAPQTKGSLKKISIVTNWNAPQNIEEQDIVMKKQVIRRCEHGH
                     KTRTNTILSKFPLQSGKQKTPSETDVDKKTTAHLSLQMLPGIHMDMTEIDPAKGGRKQ
                     ALLISEQEEGVLEFLPKSLFPPWTFQFQSGDLEEKHQTDANTNINLEQKKLEMDNDST
                     VNQKEGKLKIGTNRALHLQEEKTEMHKARTANLEKERGRMDTSSSAHPHLLSLKAEES
                     QMKTQVITHRENSRLIMQKQKKELEASNAKQSIQLQKLFQRNVLDSFYSYVPLSPKRK
                     DQKGRLTIRDLKRELSTKYLTMKIQNHPIPQMLNITGRGTPSNRKKLEYDVKLKNIAS
                     WSKDVSGIFIRSLSISIMRSPHTDPKTNLEREKRICLPKFQEKSPNTSEMSKRDTLTI
                     VKGEQNFTNTVPQDPQPFAVDKQQMQKLPNVKSEANLRSEMNKKYLKAQTKERIVPEH
                     DVSRIIKKPDLRIIEQEEKILKRILTPTECPSMLEDPKLPKQRDQSEPVWDMTTQKVQ
                     QQKAFPGTVPIPPQVKSSEVKIVADSTNAEHLLPICEATKAISESQVKNMIQDKVSSD
                     KLDNIQAYKPDDLKSPPFPEGPDTISTAIYPKTQHKSLLEQFTPKEKNKLTSHLESKA
                     LEIQLNLIPEMARKSLQMFNFYPKGTISKDNSWRFYSRHKTMNFMSLEGTDTIEPNSK
                     HKHQKDSPLASNMKTLIVDVSSDSEETITKLQSINKLENGTSAVTSASEMLLPHTLQN
                     HSVKEKGKLLMHFSVKTLEIQMKAFPRIVRESYAMTSAHERKKPLSNCIHPGFTGPKR
                     QNRILLLSEEKSLHQIDLDLQYKYLRFLLGLPVGSTFPKPNVLPKHSKLNTIAVCKNV
                     NAGGQSGSLSIDTELLEQHISFKKQSPHENSSLIRKFPQPTLVCASDRDLHSPRKKDT
                     QVLSESEFHVTPEKNKQYHVWFQERNTCESVDLRTQRNATGSAVSCETQISEDFVDIQ
                     TDIESPADLDECSCLEVSESEECVFLEANSYLSQESENILFELQTGIPLENVYKITTD
                     LKSFYSEDSGSHCTRECRKETLIITPPSCKSHKSRKYRSSSKMKSPDWLCHSSSNTAE
                     IQSRSSSVSFSEEKISWTTKSRTSYSSAPLTESNIKSHLAKNQGKSHRHPESQERKKA
                     RSDLFRKNSSHWDHDYSCTHSKGKRDRKKRVYDYESERLDCFQSKHKSASKPHHDDIN
                     FYSERKQNRPFFFACVPADSLEVIPKTIRWTIPPETLRKRNFRIPLVAKISSSWNIWS
                     SSKKLLGSLSGSLTTVFHS"
     exon            372..405
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /inference="alignment:Splign:2.1.0"
     exon            406..448
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /inference="alignment:Splign:2.1.0"
     exon            449..21470
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /inference="alignment:Splign:2.1.0"
     regulatory      21449..21454
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /note="hexamer: AATACA"
     polyA_site      21470
                     /gene="CCDC168"
                     /gene_synonym="C13orf40"
                     /note="major polyA site"
ORIGIN      
        1 gcacttgata agataccagc agcactggcc aaatgttgca catggttatg agttgggcat
       61 accgaggttt tatatttcag ggcctctgaa atcaaggact tctgaatgag acaccagtct
      121 ctttcacata tgacattaaa atgtcaaagc aatattattc ctttaaaaaa ggggtaggga
      181 gtggactgga agataataca ttcatgacat tatgggactt tctagagtcc tggattattc
      241 aaaatgattg ggtggcaatt ttctttataa ttttactagg aattattttt gagataatac
      301 tcatgaaagc ttgtgcatcc ttttggaaga agcccacact tcctgaaaag ggtagttcag
      361 atgtccagga gacggaagac agttgcccca aaagcaggaa acttgctcca gagaattggt
      421 cagttattaa ttcatcttca ggagaaagag ttggcacctt tttagaaaaa agaattactt
      481 catcacttac atctgaagaa aaggaatgta actttgaaga tagaatttta ttctcacgtg
      541 aaatactatg gtcaggtact agtgaaagtg aagatcaagt aagtccctct agtgaaagtc
      601 atgtgccatc ttcaaatgga atcagctcat ctttgccatt gttttattca gaagtagagg
      661 aaacgtgtct aagccataca gagcatccag acagagaata tgaaacaata caattttcct
      721 ccaagaaatt attttcaatg atgaaaacca acaaaaacaa aaattcagga ttttcttctg
      781 atcttagctt ttcagcatct agattcactg tagaaaatga agatctagat gtggcacctt
      841 gccctcttgc ccacttattt ctttctagag atcaagttag acttctggaa gaaaatgtga
      901 ggaatcaaat tccttcaaaa cccaaaacta agttagggag cagaactact tatcaatgct
      961 caagatctca agagtccttg aatcagaatc aaccttctgt tggaatggtt atttctgtcc
     1021 aagcacagga ttcttttcca ggacaaaatg cttttcagaa tcaaggtctt tatgaagtcc
     1081 aatttactag tcaagcccaa tatataaatc ataaccaaga atcaattaag agccagcctg
     1141 agagcaaagc cagcaacttt gcccagcctg aagatgtgat gaagaagcca ttttctagca
     1201 gcacacaaga ctccttccag tcccaagatc tggataggaa ccaacatttt gttgaagttc
     1261 catcaattgt tgaggcaaaa tattcagtaa agggcctgga gtctgatgaa cacttaggtg
     1321 aggaccaaca ttgtgtttgg tttatagatt caaacaaggt taaatattca attaaggggc
     1381 aagacactat ttttaagaat gctgaatttc tcgttttaac tctgaatcca aatttagtca
     1441 ctgaagatat gccacaacta aggagtgtaa aagcacaagg ccagcaacaa attgtttcat
     1501 cagaattgaa ccaggattct gtatatagct cagtgcctct tttgtctacc attaaagggc
     1561 agaaaaatag aagaaaaaca ccagacagta aaagcaaact cagtcttaat gttccatctc
     1621 taaaagccaa aaaaacacca acttcacaag tatttcaaat cacagtatgt cacactttaa
     1681 aaaataggaa tgagttagga tgcaagaata acactgagaa gaaagaatta catgaaagga
     1741 aagatatatc agatatagct ttgcatctta tttctgtttc caagcttatt ctgccttatg
     1801 ttaaaaatta ttccagaaaa caactagtga aagtcatgcc gggtttaata aaatgtggac
     1861 attttctgca gaagcaaaat aagtcaccag atacagagaa aatcaattat gcaggtcctc
     1921 ttgaggagac aggaatctca gatattacta aaaaggaaaa ggagtatgac aaagaaaaca
     1981 aaagactaaa aaacatttca ccaaaaatgt tacctcagct agaacaatcc ttcatggtca
     2041 acactgttca actaaaagca ccttgtttac tagtagaaac aaatgggaag agtaaagaat
     2101 ctcttaaaga ctcaattaca caagcaaagg gaattggtat tacagaattt catgttctaa
     2161 atagtaaaaa accatttgat ctccatattc caaagcacaa gacatcttta gaagaagcta
     2221 tatcaaaacc tatgcagaaa cttgtttcct ctcctgaaat ggaatcgaac aatagaatga
     2281 aaatacagga ggacctacaa agttcagaaa attcccatct tcaactttca aatggagagg
     2341 agttaccaac cagtacacca aaaacgcaaa ggtgctttcc aagggaaaat acacagaaac
     2401 aaaaagattt tttggaactt gttctggagt tgtcaaatgt cggtttgctc atttccccag
     2461 gaagcaaaat gcataaaagc agtgaagaat tagaagccat aaaaattcaa gtgaatacag
     2521 aaagtgtaaa tctgaaggaa agtaaaccat tgatacttaa tgttacagaa gacagtgacc
     2581 tacgtgaaag tgaggaactg gaatgcaaca ctggaagtaa cataacaaat atgcatcaag
     2641 ataaagaaac gtctgatgca tttcacagtg ccacttacac taccatttct caactacctg
     2701 atacagaaac acatagcata tcaaaagcca aggcagacac attaagaata ataaggctca
     2761 gtcattcagc atcaaagcaa gagaaattac cagatgagaa ggaaacacag aacgcagaat
     2821 acattgataa gagctgtaca tttaaaaagc cacaacaatg tgatagaaag gaacaggaga
     2881 aagaggcaaa ttcagagctg acacaaggct tcaggttcag catacatcta aagcaaaagc
     2941 ccaagtatgt caaattccaa atggaacaga tcagttcagg aagtagtaaa gccccaaata
     3001 aagagcaaga agtccaacca caaactcttt ctacacaaac tattttggag aatagtccat
     3061 gccccatgat ggatccattt caagttgaga aggtgaagca aagcacagat agacctacag
     3121 acagagagag tgccggagat ccaaagaatc cacttacaat gccagagaac ttgccagttg
     3181 gtgaactttt aattgaaaca acagagtata gtgtcccatt tggtggaaac ctccaaaaga
     3241 caacggatag tcatattgca gaagaaaagg aagatgtaaa aagatattta cctgcagttg
     3301 ccctggggtc tttcaataac cacttgctta ctttaccata ttttaaaagg caggaaatta
     3361 aaaaaaaatt atcagaaaca aaaagtgtac tcagtgtcaa atatgtaatt atgaaagtaa
     3421 agaagccagc aatctcactg atgccttata ttaatatatg tggtacttca aaccacagga
     3481 aaaaaatggg aggcaatttt gaaattataa ttaaacagat actgcaagat aaaattgcag
     3541 caggtatgct tctgaatgtt atttaccctc ccatgtctat tttgcctaat actagaatgt
     3601 atagcagatt aaatgcagag aatcacagtc atatcaagct agtccaagag gaatcccaaa
     3661 ttgaaaggga agaaaagtat ccatatttca ttaatgaggg aaatgaatcc caaaacacac
     3721 tagatgctaa attgcaagat gaagtaaaag gcgtcaaaga aactctacca aaagcagtcc
     3781 tgcatgatag ctgcaacctt ggacttgatg cacatctaga gaaggagatt aaaacagaga
     3841 aagaaatgca tcaaccaatc ccattcacag aaactattat tgagtctgtt gtttctccca
     3901 taatggaact atctcatgct gagaatgtga agagtactca aaaaacacaa acagactgca
     3961 aatgcactgc agattcagag acgccttctc caatatcagg aaaatcactg attggagacc
     4021 ctttaaacca aacaagagaa agttatattc caagtaatgg aagtgataca agagaaatgg
     4081 gttactgttt tgcagaagaa aagacagaaa taccaaaaga tttaccagca acttcgccag
     4141 agactttcaa ttattgcact cctgttttat cttgttctaa agtgatgaaa aagagagtaa
     4201 catttgcact cacaacaagt acagcgaagc ccaaatgtgt aaatacaaag gctgtgaagc
     4261 catcaatctc agagacagtc agtgtcacaa gccacagaaa gaaatcagaa ttagacttta
     4321 agactaagtt taaaaagata aaccaaacta aaggattggt acctgaatgt ctaaataccc
     4381 tttgctctcc aatgcatagc agattgcaga gagagttctg tctccctgcg tctcaattaa
     4441 agcaaggaga aacagcagat aagacataca ctgatgtctt tgctaagaat agcatatccc
     4501 atgacagaga ggaaaaattg caagatggaa aggaagagga acataaagtt ttattagaag
     4561 cagcgccaca gctgagccag cacctggggt ctgaggcggg tcaaatgaag gaaatccatc
     4621 ttgaatcaga cccagtgctg aactgtttaa cactggagct acatattaat ggacaacgtt
     4681 tgcagcacca aacaggtttt gaacaaacta ctttagagac tagtctccaa atgggtcctt
     4741 tagaagctga agaactacaa aaagccaacg aaacagaaaa tgacataaaa gtccttggag
     4801 gtcctaagat tccacctccc aaagctttac aggctctgga gaacagcgat ggcttaatac
     4861 tcaatgcata tcagaaggat aatgagcttg tcaaatcaga tgaggaactg aaccaaccag
     4921 gaagtacaaa tattcaggta caaccacaaa cacattttac acaaactatt ttgaagtcta
     4981 cttcatgccc tacactggat caatttccat ttgaaaaggt agagagtcat gttaggtttt
     5041 cacctctaaa gtctggggaa gcaaaggttg atgaaatcat attttatgca agagaaggtg
     5101 gtatctcatc tgattctagc catcaaaagg aacaggctgg tggtactgaa aagaaagaga
     5161 cagcgatttt tggttcctgc atgcctgctt tatctacacc taaaacgacg agaaacttaa
     5221 aacaattttc agacatgaaa actttagtga atcccaaatg tggaattata aaggcaaaga
     5281 agccatcaat ttcatacatg ctcaatatca gggctggtgc tggtccgaaa cgtagaaaag
     5341 aactgagctg taacttgaca accaaaatga aagaactgca tcaaggcaaa aagggggtag
     5401 atgaaacata tgctttcctg actatgacac ctgacattaa caagtatagc aaggtagaaa
     5461 cagaaaaaga cacgctaaga gaaaaaagac tcagttctac tcaagtaaag caagatacat
     5521 ctccacatga agatagtatt acttcacgtg acattaaaga aacccttctt caagatgaag
     5581 agcaagaaga aaggaaacag gaggcattgt taaaagtaat tccacagcac ctgcaacatt
     5641 tcatgttccg ttcaggtcag gggaaggatc ttgactttca caaattagaa aaccaaggaa
     5701 gtaggaaaat tctgtttgtt accaaacaag atgtcccaca gcaacttcag cctgcagagc
     5761 caatacaaag agaggagaca aagaaatgcc tccagaccca aaatggcaca atatgtacag
     5821 taaattcaaa acttcttcct ctaaaatcag aggactcagt aaatggtgaa gttttaactg
     5881 gtgcaataaa acgtggtgta ccaactgata ggaaatgtat gggggaacag cacaattcag
     5941 gtaaagggga aaaggcagag tttaataaag atctacaagc aactgtcctg gagttacaga
     6001 aatcaccaca tggtggggag gcacagaagg ccaatttgac tgacatggaa agtggatcta
     6061 gtaatgcaat gaacatgaat gtacaacatg aaagggaaga taaaaatatt caaaaaatgt
     6121 taacagaatc agttccatgc tatagtcaac acctccgttt cagtacacat caaatgaaag
     6181 atcctgaccc ttgcaaatca ggatctgaac cgaagagtcc cgaaggcaga tcttggaatt
     6241 tgtctcacat agtgcaaaaa acaaagcaag aaacacactt tagagaaact gttttagagc
     6301 ctatttctgg atacatgatg aaacaaagtc ctcatatgca agaaggaata aaatgtatgg
     6361 aaggtctaaa gacttcattt cccaaaacag ggaaatcaaa gattggttca ataccacgtg
     6421 ataccccttg ggatgaaaat cctagaagga aatgggatag ttctatttct gagaaaactg
     6481 catggaatca aaaaaactta caaacagtct taaaaccttt agatttctcc agcctcatgt
     6541 catctgaata tgaaagccgg agctatacat tagagtttat aggcaagaaa agtatgagtc
     6601 ccaaatgtgt aactttgaag gcaaagcaac tacgaatttt gcagttgttt aatatcataa
     6661 gatattctac agaaaaccac agaaagaaaa agcaacaccg ttttaagtac aagatgaaag
     6721 ggaagcaatg gtacacaagt ataggagagg cattactcag tgccactgaa tatgctaaga
     6781 gtacaacatc caaatcaatg attgataaac tcttatacaa tacagcagcg aggtgcattc
     6841 tatctaacag aacacgccga caaaatctgg atggtcatat tacagaggaa aaggaagagg
     6901 tacaagaaaa tgtagctgca attttcttgg gtcttttaga tttcttcatg cctgttttat
     6961 ctgactctaa aaaccagagg aacacagcac agttatcaga aaaagaaatt atattcaatg
     7021 ccaaatgttt aactatgaag gaaaagaagt cgtcaatttc acagatacat aaaatcaata
     7081 gagagtctac cagaaaacat aggaagaaat gtaaatccta tttaaaaact gtatccaaca
     7141 gaaagtgcca agaaaatcat ggtcatatta cagaggaaga ggaagaagta caagaaaact
     7201 cacctgcaac tttcctgggt cctttagatt tcttcatgcc tgttttatct gactctaaaa
     7261 accagataaa cacaatacag ttatcagaaa ggaaaattat attgaatccc aaatgtttaa
     7321 ctatgaagga aaagaaacca ccaatttcac agatacataa aatcagtggg cagtttacta
     7381 caaaacatag gaagaaactt gaatccaatt taaaaaccaa actgaaagca atgtggcaag
     7441 gtgaaaatgt ggctgataca tttccaaata caacttcctt cactccagat tcctctgaca
     7501 ttaaaaggca aagtggattc caaacagaga tagacatgag aatatcaggg ttaagtcata
     7561 cacaaccaac acaaatagag tcactagctg aagggatagc aaggtattct gatcccattg
     7621 acaagagaag aacttccaac ttggtaaagg gagcaaaact acatgataga gaaagtgggg
     7681 aagagaagca agaacatctt acagaaatgg atccattcta tgcagaaaac ttcatggcaa
     7741 acacatatct tagaaaggat cgtcatcttg gtaaatcaga ggatgtgctt ttgggagaaa
     7801 cttttttctc aaaaagtcag atttacaaag ggaattcaga aaaaaatgta aaaatagaaa
     7861 aaaacaaaaa tggaaaagaa agtctcaaag ttgggctcgc aaggatggag aaatcagata
     7921 attgtgcaga actgagtgag gcaacagatg atgccatatc aaacaaatat gataaacaga
     7981 acattggcca ttctgtttta aaagaaaatg ctttctgtaa tttggcagca attgtcccag
     8041 attctgttgg caggcattca cctgcttcag aagaaatgaa aagacagaat ggcagactta
     8101 aaatggctga caggtcaagt ccccaaggta gacctttgca ggcaaagcaa tcagcagttt
     8161 cacaatcacc tgatactgca ggttatgctg ttgtaagcaa taataaggag cagaaacaga
     8221 actttaaagc ccagaagaca gaagcagaag ttgatttaat agatcaagaa gcaaagataa
     8281 atgttgcaga agagtttaat ccagaatctg tttttttctc taagatacat ccacttcaaa
     8341 ttgaaaacaa gaaagaattt aaaactgcag actggaaaac aagggcagat cccaagacat
     8401 ttgccctgcc aaagaaacag caagagctgt gtgtctcagg aactatctgg agttatccta
     8461 atccctacac atctatttct cctaaaatca taagacataa agataaggca aagacagcag
     8521 atgtggaaag tactatgcat accaaacaga taaaattgaa ggcaaaaaga ataacagttt
     8581 cccagctgct tgagtatggt actgcaagca ataaaaaaga actgagaggt aacatccagc
     8641 agcagaagtc attccagctg agtaaaaatg cagtacatcg agttctaaag gctgtttatg
     8701 actctggata ctgtgtgtct agcattaaaa agcttacaga agtaaaaatg gagaaagaca
     8761 agccaaaaga caggacatgc attcttccac agccaaagct ggagaaacca ctaaaagaaa
     8821 tgcaaaggtc attgtcaggt tgtactgata tgtccagcat tcttagaaaa caggaacaag
     8881 atattagaga aaaggaacaa aaacaccaaa gcatttcaga agacatatcc caatactata
     8941 ttggaccgtt aaggattagt tcacaacaaa tcaattacag tagtttcgat gccccacgaa
     9001 ttagaacaga tgaagaactt gaattcctca ttgcacaaag agcaaaggaa aaagatgtgg
     9061 gcattgccaa acattcagtt tcaattccgt gggagagaga aggatcgaag agactagata
     9121 ttccactaaa ctcaaaagga cagaatatat tttttacaga gttggatact tctcaacaga
     9181 agacttgcca ggagcaagaa ttgctgaaac aagaagatat ttctatgaca aacctggggt
     9241 ctatggcctg ccccattatg gaacctcttc atttggaaaa cacaggaaag gtaactgagg
     9301 aagaagatgt gtacattaac agaaaaatta gttcacatgt attgggaaaa gaaggattaa
     9361 aggaaactga tatatttgta ggttctaaag gacagaaatt tctttgtaca aattcagagg
     9421 tacagcacaa agtgcctgca gagcagaaag aacaggtgaa tccagatcat gttcccgaaa
     9481 gtattctgga ttctgaatct ttcctcagta aggaccctct tcacttaaaa caggcagtga
     9541 atacagcaag aaaagaaaat gttaccatct ctgaaagttt caatgaaaat ctttggggaa
     9601 aagagcaatc aaagttggat attacattaa aatcaaatag acagaaaatg gacttttcaa
     9661 aaaaattgag gatgaagcat ctaagtaatt attatcagaa taaagagaat attctggaat
     9721 ctgttctccc ttgcatattg catcaacttt atattgaaaa tcccaagaaa gaaggctcag
     9781 cagaagaaat catgagttca aaagttctaa gcccaatggt agagaaagca tcacatgaag
     9841 taggtattcc ggtggatcaa cctccatgtt cagaaggaat acatttgaat attaaaggaa
     9901 gaaaagaaca tccacaagaa agtacacacg aggcttttcc agcatctgtt tctcactctt
     9961 taatggacgt acttcagatt aagtcaccaa aggtaaagaa agcattaaag gcaatcaata
    10021 gtttagggta cctcacttca aatacaaaag gaattggctt gctttttcca agacaggcag
    10081 aaaaggaaga aaaatataca tacaaggctc ttccaaagcc tgcatctcac tccaaaacag
    10141 atctatttca gttcaatgca tctatgcaac aagagaaatt agatgctatg gatattccac
    10201 attatgacta tttaacttca cagacaagag aagcagtgaa acaaatggat gtcatagttg
    10261 gatatactca aaacagtaaa aaaagacaag acttactcaa aacaggccaa aaatggcagt
    10321 acctaccaat ttcctatgag aacttttggg agcatatatc ttgccctcaa aagtatccct
    10381 gtctcctgca acatttaatg cctcaggaaa aggaagcatt atcagaagga ggtaatttat
    10441 caagccggac accaggacta gacttgtttt ctgcagatca gctaagcact ataactaaga
    10501 atagactaga atggattgtg cccttgattt ctccaaggca gatgaaaaaa caagattcaa
    10561 tgctgccttt aggatcatac cataaaacta taaaatatgc aagtctctta tttccaaaag
    10621 gaatgaaatc atcagatggg gtacaggtct ttgatttaat atcaaataat agctcaccca
    10681 agttaagact tgggaagaag atagaaacac aaaaggcaaa tgaaaaggta caaaaagaag
    10741 tatgtctgcc tataacatta cattctcttt ctgcatccat gcctattttg caagaaagta
    10801 aaggacagaa ggatagcgta gaacaagtta ttaggaaagg cgtgatatgc cacaaaagga
    10861 gaacttcgaa atggaagaaa tcagtatttt cacatatact caataccagt gactgtggtg
    10921 cctcaagtaa cagactagaa atgcagtgga acatgacaga caaaatggtc aatgtgaaac
    10981 atagaatgag tgaaatagat ttggttgcag caaaaatatg tgagtctatt ctttctttac
    11041 ctcacttcaa attgaataaa gaaacaattg atggggtgat ctcaagtaat gttaaaagta
    11101 caaaacaaca catatcacag ggaaagaatg atagagtaaa agcaatggat atgaaaagaa
    11161 taaaaagccc taacatcatt ttgaagccaa ggaagtcatc actgtcacat atactcagta
    11221 taaaggaatt tcctttgctg ttagacatta taaaacaaga gggcaagatg caagaaggta
    11281 aaggtaaatc aagtatgaaa ctgacaaact tgtgtacttc tttaccatct ctatcacata
    11341 gtaattcaaa ttcaagaaca aaagcaggta aagataagtc aggaactcta aagggctgcc
    11401 ttccaccact aaagctccag gcatcatcaa atgccagaag agtatcatct gcagagtcaa
    11461 ttaatagaga cagtttaagt aatgtaatag aatcaaagtg ttttccacag aaaaagaagg
    11521 aagatagaga aaatatagta gatgtgaaag atgtaatggg cctcaaatgt atcactttga
    11581 aaggaaagaa atcacttttt agacatttac tgcatggaaa agaaccacaa cggagcaata
    11641 aaaaactaga gaaaatgacg caggaagatg aaagtaatct aaatgtagtt cagaataaac
    11701 tctgtgcttc tattctttct ccacctcact tggaatggaa tcctagaata aaagaggtat
    11761 acatgagagg aataacaaga ttctgtcttt catcatcaac acagcaggaa ttatcagata
    11821 caatggaaaa atgtgagcag ccaattgatg atagtttaag cagtattgaa aaagcaaaac
    11881 atatgccgca gaaagacaaa gacagagtgg aaaaggcttt ggaaaaaatc atgcattcca
    11941 aaagaatagc tttggaggtg aagcagcctt caatattcca agaattagag ttgaacatca
    12001 aagaaaaagg aggaaagatt caggaagata aagaagttga gatttggagc aaaccttttg
    12061 cttccatctc ttttctacct tactctaaag tgggcacaat agaaggagag gaagccatga
    12121 gaataaaaat gagatcctct ttttcacaac caaatctcca agagtcatca gatacagaga
    12181 aaacagcata tgaaaagtgt atttctgata atatctcaaa cagtgtaaaa aaggccctag
    12241 aatctatatt gcaaaaagaa cagaggcaaa aaatggaaaa aattagggct ttgaagaaaa
    12301 tgaaatcatc aatttcacag ggaattcagt tggacattaa agagcaagag aaaaggatag
    12361 aacatattaa aggtgaacca agtgtgcttc tgacaaatgc ctgcgcttcc attccttctc
    12421 cttctcattt acaactggat acaaggagag aaaaagcaga gtatgtcact gaaataacaa
    12481 gatactatct tccagaacta tcacaccaaa aatcatcaga ggcaggggaa aaagcagatg
    12541 gagtggccag taagggtgat atcacaatca aagtacaaaa agcaaaagat tacatgcaac
    12601 agaaagaaga cgatgaagta aaaatatcag ctaagaaaga cataatgcat ccagaagaca
    12661 aaggtctgaa agcaaagaag gcactttcac aggacctacc attgaatact aaagagccag
    12721 ggaaaatgga tcaagaagct caggagcaag ggaaagagga cagagaaggt gaggagcaag
    12781 ggaaagagga cagaagaggt gcaggacaag aaaaggttga tagagaagac aaagagcaag
    12841 ggaaaatgga tcacgaagtt gaagagcaac agaaagcaga tggagtaggc atagagcaag
    12901 ggaaaatgga tggagacaag aatgaacagg aaagagttct gttcctatat ttgccttcca
    12961 attcttctct aacccattat atattggaca caagaataga aggagaggaa gaccaacaag
    13021 gaataatcag acctggtatt ttacaaccaa ggcaccagaa atcatcagag acagggaaaa
    13081 aagcaaatgg ggtgcccagt gagggtgata gcgcaagtga agtacaaaaa gcaaaagatt
    13141 acatgcaaca gaaagaagag gatgaagtaa aaatatcagc tgagaaagac ttaatgcatc
    13201 cagaagacaa agatctgaaa ggaaagaagg cactttcaca gaacctacca ctgaatccta
    13261 aagagccagg gaaaagggat ggagaaggcc aggagcaagg gaaagaggac ggagaaggtg
    13321 aggagcaagg gaacagggat ggagaaactg aagagcaaca gcaagcagat ggagtaggca
    13381 cagagcaaga gaaaagggat ggacacaaga gtaaacagga aacagttctc ttcctacatt
    13441 tgccttctga gtcttctcta acttgttatg aattgaacac aagaaaagaa ggagaggaag
    13501 acttacaagg aataataaaa tctgctactt tgcaactaag gcagcagaaa tcatttgatg
    13561 cagggaaaat agcacataca aagtcttttg gggtggatag ctcaaatgat gtaaaaacag
    13621 tacaagaata caagccacag aaagaagtag atagaggaaa aacagtaagt gtggattata
    13681 taatgcaacc tgaaggcaca atttttgagg cagagcaatt atcacttcca catacactca
    13741 atatccctgg cagcagtggc tcaaaaacta gagaagtact aacaaacata aaagaaaaat
    13801 tgagacatgt acaggaaaga aaaagtgaac tggatgtgtt tctgacaata ccttctctat
    13861 ctcactgtaa attagacaaa cgaacagcag gcaaaaaaga ggaacaagga gtaacaagat
    13921 cttttcttcc accctcatgg cacatggaat catcagatac agggaaatta aaatatacat
    13981 tgtcatattt gaatgatatc acaggtgatt caaacagaac aaaatacatg gcccagatcc
    14041 aaaaggataa agcaaatatt tcagagaaaa gtgtaatgca tcccgagtac atagctgtaa
    14101 aggcagagaa atcacccctt tcccatatac taaaaacaaa ggaactgcag gtgaacatca
    14161 gtcaacaagg ggaaaaggca caagaaggtg aggtggaaat agttgtactt ctgagcaaaa
    14221 cttgtccttt tgtcacttct tcagctttcc ttgagttaga ctcaataaaa gaagaggaag
    14281 gtgaaccacg aataacaaga agctttatgc cacatcttga gatccaggaa tcattgcctt
    14341 caaggcaaac agcacctaca aagccaacag agagccttgt aaagaaagag aaacaactcc
    14401 ttccacagaa agaagacaga gtacaaacag tatccatgca tggcctgatg caccccaatg
    14461 gtgccgtttt caaggcaaag acatcagcac ctccacaagt gttcagcatc actgagcaca
    14521 gtcctctgag taagagaaag gagccacagt ggggcatgaa agagagagca ggacagaagc
    14581 aggacaggac aggacgtcct catgtgattc tgacaaaaac tcatccattc atgccttctc
    14641 tctctcacca tagattctct ccttcacaac caaagcttcc tatatcatca ggtgcaggaa
    14701 aaagcagact tgcaaattca aatgaaggta ttagctcaca taaagtaata ctaaaagcaa
    14761 accaacaaat gccatataaa gaggcaaagg acagagtaaa aatagaaggc agggaaggta
    14821 gaatactccc caaaaggata catttgaggg cagaggcact cccacttgca cttctatgca
    14881 atggaaagaa ctactctttg cacattgaag agcaagggga aggagtacag gaaagcaaaa
    14941 aggaacctgg agtggttccg aggaaatctg cttcattccc tcctcctcca ttttacctga
    15001 attgtgacac tagaaggaat gaaaaggaag gcacattagg aaaaacacaa ttcagttttc
    15061 caccactaaa gattcaggat tcatcagatt caggcaaaaa agcatatact gagtcactgc
    15121 atggttacac attaagcaac tcaaaaggac cagtgcaacc cacagcacag ggagaagaga
    15181 aaggtggact cagaatagat atggaagaca aaatgctccc caaatgtaca gacctgaaag
    15241 caaagcaatt actactctca gatatactca ataccaaaaa attgcagtgg aaaagtaaag
    15301 aacaaaagag aaagattcag gaagataaaa ataaacaagt taaaggactg ccaagcatta
    15361 atacttcttt acttactcca ccatatctta agtttgatac aacagaagga caggagaacg
    15421 tgataagaat tgcaaaagtg tctctcccac agtcacggtc caaggaatca tcagatgcag
    15481 ggagaatagc atgtccagaa gcaacccatg gagaactttc aagtgatgta aagcaattaa
    15541 aagcacacct gctacagaaa gaagagaagg atagagaaaa agttgcggat atgaccagtg
    15601 tactggatcc caacaaaatg tatttgaagg caaagaaatc gcctgtctta catacgcaca
    15661 gtttcagtga tcttcagtgg aaaactagag agcaagagga ggaaaaggtc cagaaagtta
    15721 aaagtgggcc aggtgtcatg ttgtctaaga gtccttctag atcctcccca cttcacctta
    15781 atgtgaatac agggtttcag gaggaaagca taccaatatt aacaagaccc tcttttcccc
    15841 tagtaaaact ccaggtatca ccagatactg agggaggcac atgtataagg ccaattgctg
    15901 gtgatatttt aatctatcta caaaaaggaa aacatgtgtc acagaacaag gaagaggatg
    15961 acgtgcaaat agtaagcatc ttaatattcc ccaaacatca ggaagagaag gtgcaggaat
    16021 gtgaaggtga accaggtgtg gttctgacca aatctacttc attgccatct ctatctcaac
    16081 tagaattgga taaagaaaca catttaggta atgaaatgct aagacttaaa agacctattt
    16141 tgcggagaat atcacacata ggggagactg tacatagaga gtccgtcgtt ggtgatatcc
    16201 caaaagatgt taaaaatgaa aagcaacata tccctcaaaa agaagagagg aaccaaaaaa
    16261 aaataatcga tatgagaggc acagatataa ctttgaagtc aaagaagtca cctcgttcct
    16321 gtatgctcca cagaacagaa ctgcatgtga acattggagg gcaaggacga aaggaacatg
    16381 aaggtcaaga taaaccacca ggtatgattc aaagaaaaat gtgcatactc ttttccaaac
    16441 ctttgccatc taaccttaaa ctggagagag ctacgcatgc agatgaagaa aggcttggag
    16501 gtaagacatc ctttgtactt ccactaatgc catcagcatt accagataca gagaaaacag
    16561 cagatgcaga ggcaaggagt ggtgatgtaa gaaaaggaaa accacatagg tcacagaaag
    16621 aaaacaggca tgaagtgaaa acgatagata tgaggttcag gatacactgc caagaggcaa
    16681 ggatttcacc aatgtcacat atccttaatg caaaggaatt agtgttgaat attaacaaac
    16741 tggagaaaaa agtacacaaa gataaagatg aagcatgtgt ggttctgtca aggacttttc
    16801 tttctatacc gtcagcacct cctctttatc tggattcagg gaacaaaaca gacaaagaca
    16861 ctccaggaat tacaggatca tcttgtccac agcgaactct ccatgtaccc tcaaataccc
    16921 agaaaataac aaatagagac tcagttgaag gcgttgataa aaacgttgtt aagcaagcag
    16981 aacagtatgt gccccgccca gaggcagagc aacagttgac ctcaaacttc atgatcagcg
    17041 tccagcaaag gaaccaacct tcacgagtca ggtcagaaga agatttgaat cagttagttt
    17101 taaactcacg ggatgaggac atttatttca cagggtttgg taccataaga agtgggaaaa
    17161 ggccggaatg gctctttaca gggaaaaagg ctcagcctgt aaaatacaaa acagaaactt
    17221 taactgcgtt tctttcctat cccacaatgg atgcaactaa aatgggaggt ctggaagaag
    17281 acactgaaat aatggataac ttaaaccata aaatcagtcc taaggcttca gtttcactga
    17341 taaggaaaat atctaaggaa ctgtatgtca cacttggcac ccctgcaaat tcaaaaggat
    17401 tttctgtttc agagagatac gctcaccagc aagaaacttc atcgaaagta tctccagaac
    17461 ttgcaggttc atgtaaattt gataagccaa aggaagatgg acaaagtaat gatagaatca
    17521 gcaaaatgtt ttctcccaaa gtgttagcac cacagacaaa gggatcactc aaaaaaataa
    17581 gtatcgtcac caactggaat gccccccaaa atatagaaga acaagatatt gtcatgaaaa
    17641 agcaagtgat ccgacggtgt gaacatgggc acaagaccag gacgaacact atcctttcta
    17701 agtttcccct tcaaagtgga aagcagaaga caccatcgga aacagatgtg gacaagaaaa
    17761 caacagcgca cctcagccta cagatgctac caggaataca catggatatg acagagattg
    17821 accctgcaaa agggggaagg aagcaggcat tgctcatttc agaacaagag gaaggtgttc
    17881 tggaatttct tccgaagtcc ctattccctc cctggacttt tcaatttcaa tcaggggatc
    17941 tggaggaaaa acatcaaaca gacgcaaaca ccaatataaa tctagagcag aaaaaattag
    18001 aaatggacaa tgatagtact gtgaatcaga aagaagggaa attaaaaata ggcacaaaca
    18061 gagctttaca tctgcaagaa gagaaaacag agatgcacaa ggccaggact gccaatctgg
    18121 agaaggagag aggaagaatg gacacaagca gtagtgcaca cccgcatctt ctatctctaa
    18181 aggcagagga atctcaaatg aagactcaag tcatcactca tagggagaac agccgcctaa
    18241 tcatgcaaaa gcagaaaaaa gaactagaag catctaatgc aaaacaaagc attcaactac
    18301 aaaaattatt tcaaagaaat gttctggatt cattttattc atatgttcct ctttctccca
    18361 aacgtaaaga tcagaaaggc agattaacaa taagagatct gaaaagagaa ttgagcacca
    18421 aatatttaac tatgaaaatc cagaatcacc caattccaca gatgcttaat atcacggggc
    18481 gtggtacacc aagcaataga aagaaattag agtatgatgt taagttaaag aacatagctt
    18541 cgtggagtaa agatgtctca ggaatattta tcagaagtct ttctatttcc atcatgcgtt
    18601 cacctcacac tgaccctaag acaaacctag aaagagaaaa gagaatctgt cttcctaaat
    18661 tccaggaaaa atcaccaaac actagtgaaa tgtctaagag agacacttta acaattgtaa
    18721 aaggggaaca gaattttaca aacacagttc cacaagatcc ccagcccttt gcagtggaca
    18781 aacaacaaat gcagaaactt cctaatgtca aatcagaagc aaacctcaga agtgaaatga
    18841 ataaaaaata cttaaaggca caaacaaaag aacggattgt tccagagcat gatgtctcaa
    18901 ggatcattaa aaaaccagac ttacgtatca tcgagcagga agaaaagatt ctaaaacgca
    18961 ttctgacacc cacagagtgt ccatctatgc ttgaagatcc aaagttaccc aagcaaaggg
    19021 atcagagtga accagtatgg gacatgacca cacaaaaggt tcagcagcaa aaagctttcc
    19081 caggaactgt gcccataccg cctcaagtta aaagtagcga agtcaaaata gttgcagaca
    19141 gtacaaatgc agaacattta cttcccattt gtgaagcaac caaagctatc tctgagtccc
    19201 aggttaaaaa tatgatccaa gacaaagttt cttctgataa actagataac atacaagcct
    19261 ataagcctga cgacttgaag tcaccacctt ttccagaggg tccagataca atatcaacag
    19321 caatatatcc caaaacgcag cacaaatccc ttttagaaca gtttactccc aaagaaaaaa
    19381 ataagcttac tagtcattta gagtcaaaag cacttgaaat acaactgaat ctgataccag
    19441 agatggcaag gaaatcttta caaatgttca acttttatcc aaaagggact atttcaaaag
    19501 ataacagttg gaggttctat tctagacata aaacaatgaa ctttatgtct ctagaaggga
    19561 ctgataccat agaacctaac tcaaaacata aacaccaaaa ggattcacct cttgccagca
    19621 atatgaagac actgattgtt gatgtttcaa gtgacagtga ggagacaatc acaaagctac
    19681 agagtattaa taagctagaa aatggaacat ctgcagtgac ttctgctagt gagatgctat
    19741 tgcctcatac cctccaaaac cactcagtaa aagaaaaagg caaactcctc atgcactttt
    19801 ctgtgaaaac attggagata caaatgaaag cctttcccag aattgtaaga gaatcttatg
    19861 caatgaccag tgctcatgag agaaagaaac ccttatctaa ctgtattcat cctggtttca
    19921 caggaccaaa acgacaaaac agaattttgt tactttctga ggagaaatct ctccatcaaa
    19981 tagatcttga tttacaatac aaataccttc gttttctcct ggggcttcct gttggaagta
    20041 cgttccctaa gccaaatgta cttcccaaac atagtaagtt aaacacaatt gcagtgtgta
    20101 aaaacgtaaa tgctggtgga caaagtggta gtctttccat tgatacagaa ctgttagaac
    20161 aacatatttc tttcaaaaag caaagtcccc atgaaaactc atcactcatc agaaaattcc
    20221 cacagccaac ccttgtgtgt gcttctgacc gtgatctgca cagcccgagg aagaaagata
    20281 ctcaagttct ttcagagtca gaattccatg tgactccaga aaaaaacaaa caatatcatg
    20341 tatggtttca agaaagaaat acatgtgaat ctgttgattt aaggacccag agaaatgcta
    20401 ctggttcagc tgtttcatgt gaaactcaga tttctgaaga ttttgttgat attcagacag
    20461 atattgagag tccagctgac ttggacgagt gttcatgtct tgaagtaagt gagagtgagg
    20521 aatgtgtgtt tctggaagcc aactcttatt taagtcagga atcagaaaac attctatttg
    20581 aattacagac aggcattcct ttggaaaatg tctacaaaat cacgactgat ttgaaatcat
    20641 tttacagtga agattcaggt tcccattgta ctagagagtg cagaaaggaa accttaatta
    20701 ttacaccacc ttcctgtaag tcccacaaaa gcaggaaata tagatcatct tccaaaatga
    20761 aatctcctga ctggttgtgt catagttcat caaatactgc ggaaattcag tctaggtcat
    20821 ctagtgtatc attcagtgaa gagaagattt catggactac caagagcaga acaagttact
    20881 cttcagctcc cttaactgaa tcaaatatta aatcacatct tgcaaaaaac caaggcaagt
    20941 ctcacaggca cccagaaagc caagaaagaa agaaggccag atctgattta tttaggaaga
    21001 acagcagtca ttgggaccac gattacagtt gtacacacag caaagggaaa cgtgacagaa
    21061 agaagagagt gtatgattat gagtcagaaa gattggattg tttccaaagc aaacataaat
    21121 cagcatcaaa acctcatcat gacgatatca acttctattc tgaaagaaaa caaaaccggc
    21181 cctttttttt tgcctgtgta ccggcagact cactggaggt tatacccaaa accattcgct
    21241 ggactattcc ccctgaaacc ttaaggaaaa gaaacttcag aattccccta gtggcaaaga
    21301 tttcaagttc ttggaatata tggagttcct ccaaaaagtt gttggggtcg ctctcggggt
    21361 cccttactac cgtttttcat agctgacatt accatagcta aactcctctg aagtggacag
    21421 ctggtcgcta ttgtgatatt ctgtgaaaaa tacaatcata taacatccaa
//
