LOCUS       NM_001080539            3597 bp    mRNA    linear   PRI 08-OCT-2024
DEFINITION  Homo sapiens coiled-coil domain containing 150 (CCDC150),
            transcript variant 1, mRNA.
ACCESSION   NM_001080539 XM_930591
VERSION     NM_001080539.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3597)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC068544.7.
            
            On Nov 22, 2018 this sequence version replaced NM_001080539.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA1968968, SAMEA2148093
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000389175.9/ ENSP00000373827.4
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AC068544.7         55637-55700
            65-228              AC068544.7         62263-62426
            229-449             AC068544.7         72555-72775
            450-628             AC068544.7         72880-73058
            629-697             AC068544.7         74714-74782
            698-814             AC068544.7         81489-81605
            815-944             AC068544.7         82641-82770
            945-988             AC068544.7         85755-85798
            989-1081            AC068544.7         88267-88359
            1082-1189           AC068544.7         90163-90270
            1190-1314           AC068544.7         92065-92189
            1315-1492           AC068544.7         92476-92653
            1493-1561           AC068544.7         93215-93283
            1562-1675           AC068544.7         110968-111081
            1676-1747           AC068544.7         117031-117102
            1748-1855           AC068544.7         128067-128174
            1856-1918           AC068544.7         128599-128661
            1919-2047           AC068544.7         134425-134553
            2048-2217           AC068544.7         135419-135588
            2218-2311           AC068544.7         136497-136590
            2312-2481           AC068544.7         137444-137613
            2482-2608           AC068544.7         141895-142021
            2609-2803           AC068544.7         145115-145309
            2804-2872           AC068544.7         145715-145783
            2873-3034           AC068544.7         145879-146040
            3035-3121           AC068544.7         146781-146867
            3122-3241           AC068544.7         147955-148074
            3242-3597           AC068544.7         148368-148723
FEATURES             Location/Qualifiers
     source          1..3597
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33.1"
     gene            1..3597
                     /gene="CCDC150"
                     /note="coiled-coil domain containing 150"
                     /db_xref="GeneID:284992"
                     /db_xref="HGNC:HGNC:26834"
     exon            1..64
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..3358
                     /gene="CCDC150"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 150"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 150
                     isoform 1"
                     /protein_id="NP_001074008.1"
                     /db_xref="CCDS:CCDS46478.1"
                     /db_xref="GeneID:284992"
                     /db_xref="HGNC:HGNC:26834"
                     /translation="MDCKVHMETTVSRPVLSPTHINATASETFTVLQQRMRIVEEQTS
                     SLRDDLIMLDFGEKRGYLEAPDCLEDLDSQKVISPIQNEAICAGKTDILWKNCEFLVN
                     RMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVMNL
                     RQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRR
                     QLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELL
                     AQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEHEENAYLRSEIMS
                     LHEASEKAQVLNDQLTKKCSELSCMLQTVTMEKARIIADHQAILQVEQKMMTQTFQEQ
                     NLLLDAAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLE
                     STIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINT
                     LTHNLQTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQI
                     KVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVK
                     SILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDRENKKVGNFQRQLAEAKEDNCK
                     VTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQ
                     ARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLDHIQEQLES
                     KELERQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKA
                     LDEANFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIE
                     RMKQIEKELKQMELIKDQYQKKNYEQSLSIQRFVCEMTNLQKEMQMLAKSQYDASVRN
                     KQQELHLEAERKIRQELENRCQELEETVRHLKKCKEATENTLKEASVESEQITANLEE
                     AHRWFKHRFDGLQLELTKNRLQRPSGEDRWQEKDQDVKHDVMSNQSVLHRWERKQNLR
                     PMPKKYHSEVQRK"
     exon            65..228
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            229..449
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            450..628
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            629..697
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            698..814
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            815..944
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            945..988
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1081
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1189
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1314
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1492
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1561
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..1675
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1747
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1855
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1918
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2047
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2217
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2311
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2481
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2482..2608
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2609..2803
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2804..2872
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            2873..3034
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            3035..3121
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            3122..3241
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     exon            3242..3597
                     /gene="CCDC150"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3565..3570
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC150"
                     /note="hexamer: AATAAA"
     polyA_site      3597
                     /gene="CCDC150"
                     /note="major polyA site"
ORIGIN      
        1 agttccacgg aaacccgctc gcctgctgca gtacggagcc tcaggcggac agatggactg
       61 taaggtacat atggaaacta cagtgtccag accggtcctt tctccaaccc acatcaacgc
      121 tacagcttct gaaacattca cagtacttca gcaaaggatg agaatagttg aggaacagac
      181 cagttcactg agggatgacc taataatgtt ggattttggt gaaaaaagag gctatttgga
      241 agctccagac tgtttagaag acctggacag ccagaaagtc attagtccta tccaaaatga
      301 agcaatttgt gcaggaaaaa cagatatttt atggaagaac tgtgagtttc tggtaaatcg
      361 aatgtgccgt cttgaaagcc tcatgcagtc cttgaagatg aacatctttc ggctgcaaac
      421 tgaaaaggat ttgaatcctc agaaaacagc ttttctgaaa gatcgactga atgcaataca
      481 ggaagagcat tctaaggacc tgaagctgtt gcatctcgaa gttatgaatt tgcgccagca
      541 actgagagct gtaaaagagg aagaagacaa ggcacaagat gaggtgcaaa ggttgactgc
      601 cactctgaag attgcctcgc agacaaagaa gaatgcagcc attattgaag aggaactgaa
      661 gaccacaaaa cgtaaaatga accttaaaat tcaagagcta aggagacaac tggctcagga
      721 gaagtacctt agggaatctt tagagaaatc agcatcagcc atgctcctca aaatacaaga
      781 aatgggatca acagtggagg tagaacgaaa acaggtgcac attttgcagc aaaactgcat
      841 tgctctacgt gattctatac agagcgctca agaactactg gcccaggaac aaaaaaaaaa
      901 agaagagttg gagattgcta cttcacagct caaatctgat ctaacttcta gagatgacct
      961 catttccaag ttggttgaag aaaataagaa cctgcagata tctttcaaca aggaacatga
     1021 agaaaatgca tatttgaggt ccgaaataat gtctcttcat gaagcatcag aaaaagcaca
     1081 agttttgaat gaccaattga ctaaaaagtg ttcagagttg agctgcatgc ttcagactgt
     1141 tactatggaa aaagccagaa tcattgctga ccatcaggcc attctgcagg tagagcagaa
     1201 aatgatgacg cagacatttc aagaacaaaa cttattgctg gatgcagccc atgccagtat
     1261 cacaaatgaa ctacagactg ttcagaatga gaaaacccaa ctccaggcac atctggatca
     1321 tttaatcctt gagcataacc agtgtatcca gaaagcacag gatgctgaaa agagaacagc
     1381 tgtgcaaaaa gagctgctag aatcaactat tgcaagattg cgaggtgaat tggaagcatc
     1441 aatgcaagag aagaagtctc tgctagagga gaaagaaaga tttcagaggg aggttaataa
     1501 aacagaaaaa gaaatagtgc aagaaagatg caatttggaa aaggaattag ctaaaaacaa
     1561 ggtagacata aatacattaa ctcataacct gcagactctt gaagaagaga ataagcacct
     1621 ggcagatcaa atggcttccc tagaacttca gcaagtcact tctgattacc atgggcttgc
     1681 ccaacagaag gtggaaaaaa tcactgaaag taaaaataaa ctggcctatg aaaacggaaa
     1741 actccagata aaagttaaac agctagaaga acaagtacag tcttttactg acaccagctt
     1801 acagaatgat catctacgca agatgaataa gtatttacag actaaatatg ctcaggcaaa
     1861 ctcagaactc agtgccaaga gggtacacct gcagcaggca gatgctcacc tgaaagaagt
     1921 gaaatctatt cttgaaagaa gtaaagagga gctgtcccga acagtgaagt gtcgtaatgc
     1981 ggccctgaaa gagagtcaga agttgaaaga agacctcgag gctgtggagg acagggaaaa
     2041 caagaaggtg ggaaactttc agcgacaatt ggcagaagct aaagaagaca actgcaaagt
     2101 cacaatcatg ttggagaatg tgctggcttc tcacagtaag atgcaaggtg ctctggagaa
     2161 agtacaaata gagcttgggc ggagggattc agagattgca ggcctcaaga aagaaaggga
     2221 tctcaatcaa cagagggtgc agaagctgga agctgaagtg gaccagtggc aggccaggat
     2281 gcttgtcatg gaggaccagc acaacagtga gattgaatct ctacaaaaag ctctaggtgt
     2341 agctagagaa gacaacagga aacttgctat gagtctggaa caagctctcc agacaaataa
     2401 tcatctgcaa acaaagctag atcacattca agagcaattg gaaagcaaag aacttgagcg
     2461 acagaatttg gaaaccttca aagaccggat gactgaagag tccaaagtgg aagcagaatt
     2521 gcatgctgaa cgcatagaag ctctaagaaa gcagtttcaa accgagagag aaactacaaa
     2581 gaaagtggca caacgggaag tggctgagct gaagaaagcc cttgatgaag ctaacttcag
     2641 atcagtggaa gtgtcccgga ccaaccgaga gctgcgacag aaacttgcag agctagaaaa
     2701 aatactagaa agtaacaagg agaaaataaa gaatcaaaag acccaaatta agctccactt
     2761 gtcagctaag gcgaataatg ctcagaatat agaaaggatg aagcaaatag aaaaagaatt
     2821 gaagcaaatg gagctaatta aggatcaata tcagaaaaag aactatgaac agtctttgag
     2881 tatccagaga tttgtgtgtg aaatgactaa cctgcagaaa gagatgcaga tgttggctaa
     2941 gagccaatat gatgcctcag tgcggaataa acagcaagag ctgcacctag aagcagagcg
     3001 gaaaataagg caggagctag agaatcggtg ccaggaattg gaagaaactg tcagacacct
     3061 gaagaaatgt aaagaggcaa cagagaatac gctgaaagaa gccagtgtgg aatcagaaca
     3121 gataacagct aatctggaag aagctcatcg ctggtttaag cacaggtttg atggtctaca
     3181 acttgagctg acaaaaaacc ggttgcagag gccttctggg gaagacaggt ggcaggaaaa
     3241 ggaccaagat gtaaaacatg atgtcatgtc caaccaatct gttctgcatc gatgggagag
     3301 aaaacagaat cttaggccca tgcccaagaa gtatcattct gaggtacaga ggaagtgatg
     3361 tccttgacaa gggagcttct ttatgtgtag ctacactcca tgattccaag agcccagcag
     3421 ccggggctgg cctgtttcta gagtcataag aacatgaagt ctttgatgtg ggctgaagat
     3481 tttggacctg agtttatcac tttatgaact cttatatcag tacaaaacta cccctttttt
     3541 tgtccctttt cacattttcc acccaataaa tttgtgttaa tttgttgtat gatagga
//
