LOCUS       NM_024821               7135 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens coiled-coil domain containing 134 (CCDC134),
            transcript variant 1, mRNA.
ACCESSION   NM_024821 XM_496529
VERSION     NM_024821.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7135)
  AUTHORS   Ma,M., Dubey,R., Jen,A., Pusapati,G.V., Singal,B., Shishkova,E.,
            Overmyer,K.A., Cormier-Daire,V., Fedry,J., Aravind,L., Coon,J.J.
            and Rohatgi,R.
  TITLE     Regulated N-glycosylation controls chaperone function and receptor
            trafficking
  JOURNAL   Science 386 (6722), 667-672 (2024)
   PUBMED   39509507
REFERENCE   2  (bases 1 to 7135)
  AUTHORS   Lampson,B.L., Ramiotarez,A.S., Baro,M., He,L., Hegde,M., Koduri,V.,
            Pfaff,J.L., Hanna,R.E., Kowal,J., Shirole,N.H., He,Y., Doench,J.G.,
            Contessa,J.N., Locher,K.P. and Kaelin,W.G. Jr.
  TITLE     Positive selection CRISPR screens reveal a druggable pocket in an
            oligosaccharyltransferase required for inflammatory signaling to
            NF-kappaB
  JOURNAL   Cell 187 (9), 2209-2223 (2024)
   PUBMED   38670073
REFERENCE   3  (bases 1 to 7135)
  AUTHORS   Huang,Z., Zhen,S., Jin,L., Chen,J., Han,Y., Lei,W. and Zhang,F.
  TITLE     miRNA-1260b Promotes Breast Cancer Cell Migration and Invasion by
            Downregulating CCDC134
  JOURNAL   Curr Gene Ther 23 (1), 60-71 (2023)
   PUBMED   36056852
  REMARK    GeneRIF: miRNA-1260b Promotes Breast Cancer Cell Migration and
            Invasion by Downregulating CCDC134.
REFERENCE   4  (bases 1 to 7135)
  AUTHORS   Yin,S., Liao,Q., Wang,Y., Shi,Q., Xia,P., Yi,M. and Huang,J.
  TITLE     Ccdc134 deficiency impairs cerebellar development and motor
            coordination
  JOURNAL   Genes Brain Behav 20 (7), e12763 (2021)
   PUBMED   34382738
  REMARK    GeneRIF: Ccdc134 deficiency impairs cerebellar development and
            motor coordination.
REFERENCE   5  (bases 1 to 7135)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 7135)
  AUTHORS   Huang,J., Xiao,L., Gong,X., Shao,W., Yin,Y., Liao,Q., Meng,Y.,
            Zhang,Y., Ma,D. and Qiu,X.
  TITLE     Cytokine-like molecule CCDC134 contributes to CD8 T-cell effector
            functions in cancer immunotherapy
  JOURNAL   Cancer Res 74 (20), 5734-5745 (2014)
   PUBMED   25125657
  REMARK    GeneRIF: CCDC134 promotes cell proliferation through the JAK3-STAT5
            pathway.
REFERENCE   7  (bases 1 to 7135)
  AUTHORS   Zhong,J., Zhao,M., Luo,Q., Ma,Y., Liu,J., Wang,J., Yang,M.,
            Yuan,X., Sang,J. and Huang,C.
  TITLE     CCDC134 is down-regulated in gastric cancer and its silencing
            promotes cell migration and invasion of GES-1 and AGS cells via the
            MAPK pathway
  JOURNAL   Mol Cell Biochem 372 (1-2), 1-8 (2013)
   PUBMED   23070808
  REMARK    GeneRIF: The attenuated expression of CCDC134 promoted the
            activation of Erk1/2 and JNK/SAPK, but had no effect on p38 in
            gastric cancer.
REFERENCE   8  (bases 1 to 7135)
  AUTHORS   Huang,J., Zhang,L., Liu,W., Liao,Q., Shi,T., Xiao,L., Hu,F. and
            Qiu,X.
  TITLE     CCDC134 interacts with hADA2a and functions as a regulator of
            hADA2a in acetyltransferase activity, DNA damage-induced apoptosis
            and cell cycle arrest
  JOURNAL   Histochem Cell Biol 138 (1), 41-55 (2012)
   PUBMED   22644376
  REMARK    GeneRIF: CCDC134 might act as a novel regulator of hADA2a, and
            plays roles in the PCAF complex via hADA2a to affect its
            acetyltransferase activity and UV-induced DNA damage repair.
REFERENCE   9  (bases 1 to 7135)
  AUTHORS   Kim,S., Swaminathan,S., Shen,L., Risacher,S.L., Nho,K., Foroud,T.,
            Shaw,L.M., Trojanowski,J.Q., Potkin,S.G., Huentelman,M.J.,
            Craig,D.W., DeChairo,B.M., Aisen,P.S., Petersen,R.C., Weiner,M.W.
            and Saykin,A.J.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative
  TITLE     Genome-wide association study of CSF biomarkers Abeta1-42, t-tau,
            and p-tau181p in the ADNI cohort
  JOURNAL   Neurology 76 (1), 69-79 (2011)
   PUBMED   21123754
REFERENCE   10 (bases 1 to 7135)
  AUTHORS   Huang,J., Shi,T., Ma,T., Zhang,Y., Ma,X., Lu,Y., Song,Q., Liu,W.,
            Ma,D. and Qiu,X.
  TITLE     CCDC134, a novel secretory protein, inhibits activation of ERK and
            JNK, but not p38 MAPK
  JOURNAL   Cell Mol Life Sci 65 (2), 338-349 (2008)
   PUBMED   18087676
  REMARK    GeneRIF: These results clearly indicate that CCDC134 is a novel
            member of the secretory family and down-regulates the Raf-1/MEK/ERK
            and JNK/ SAPK pathways.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX473493.1, BC017693.2, CB240942.1 and AL021453.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Apr 30, 2020 this sequence version replaced NM_024821.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1). Variants 1 and 3 encode the same isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.3350118.1,
                                           SRR18074969.1274611.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000255784.6/ ENSP00000255784.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-393               BX473493.1         47-439
            394-1262            BC017693.2         376-1244
            1263-1270           CB240942.1         17-24               c
            1271-7135           AL021453.1         46166-52030
FEATURES             Location/Qualifiers
     source          1..7135
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q13.2"
     gene            1..7135
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /note="coiled-coil domain containing 134"
                     /db_xref="GeneID:79879"
                     /db_xref="HGNC:HGNC:26185"
                     /db_xref="MIM:618788"
     exon            1..88
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     exon            89..207
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..794
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; coiled-coil domain-containing protein 134"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 134
                     isoform 1 precursor"
                     /protein_id="NP_079097.1"
                     /db_xref="CCDS:CCDS33654.1"
                     /db_xref="GeneID:79879"
                     /db_xref="HGNC:HGNC:26185"
                     /db_xref="MIM:618788"
                     /translation="MDLLQFLAFLFVLLLSGMGATGTLRTSLDPSLEIYKKMFEVKRR
                     EQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLTAADVLPDGPFPQDEKLK
                     DAFSHVVENTAFFGDVVLRFPRIVHYYFDHNSNWNLLIRWGISFCNQTGVFNQGPHSP
                     ILSLMAQELGISEKDSNFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKEEKRKEIRK
                     GPRISRSQSEL"
     exon            208..329
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     exon            330..414
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     exon            415..596
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     exon            597..668
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     exon            669..7135
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1241..1246
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /note="hexamer: AATAAA"
     polyA_site      1270
                     /gene="CCDC134"
                     /gene_synonym="OI22"
     regulatory      7115..7120
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /note="hexamer: AATATA"
     polyA_site      7135
                     /gene="CCDC134"
                     /gene_synonym="OI22"
                     /note="major polyA site"
ORIGIN      
        1 agttgctttg ctgttagcct gttggacctt cgagcctagc tgctcgcaca ggactcggcc
       61 acctgccctt cctgcaccga ctggccagct caagaggttt ggatatggac cttcttcaat
      121 tcctggcctt cctctttgtc ctgcttttgt ctgggatggg agccacaggc accttgagga
      181 cctccctgga cccaagcctg gagatctaca agaagatgtt tgaggtgaag cggcgggagc
      241 agctgttggc actgaagaac ctggcacagc tgaacgacat ccaccagcag tacaagatcc
      301 ttgatgtcat gctcaagggg ctctttaagg tgctggagga ctcccggaca gtgctcaccg
      361 ctgctgatgt gctcccagat gggcccttcc cccaggacga gaagctgaag gatgctttct
      421 cccacgtggt ggagaacacg gccttcttcg gcgatgtggt gctgcgcttc ccgaggattg
      481 tgcactatta ctttgaccac aactccaact ggaacctcct catccgctgg ggtatcagtt
      541 tctgcaacca gacaggcgtc ttcaaccagg ggccccactc gcccatcctc agcctgatgg
      601 cccaggagct ggggatcagt gagaaagact ccaacttcca gaacccattt aaaatcgacc
      661 gcacagagtt cattcccagc actgaccctt tccagaaggc cctgagagaa gaagagaaac
      721 gccgaaagaa agaggagaag cggaaggaga tccgaaaagg cccaaggatc tccagatccc
      781 agtctgagtt atagccctgg agcagctcag ggctcagggg gccacaagga ggcaggtcgg
      841 gaggaagaag aggtggaggt gtggttgtgg tggagagcac cagctagccc cttccagaag
      901 gggaggccac atttgcccgg ccccctggag ctgggtctga gccccagctg aagggactga
      961 gcctcagatg gctggatttt ctctcagggg cctcctgctg aaggggcctt cagaggattt
     1021 tatgctggaa atatgaccct gtgcagactg ctgggggagg caggaggatg cctgcctgga
     1081 ccctgttggt ggctgaagac ctctggccag ctggcttccg cccttggtgg ggaagcagca
     1141 gaactaggtt ctgagccacg ggtcagggtg ccaccctgct gctggcccca ctgtgtcaca
     1201 gagctgcctg gcacaggtcc cagcccctct gcagagacac aataaaagcc agcagaccct
     1261 ttggaccgac caaggctggt ggggacactg tgaggggacc agggcccctc agggatgtag
     1321 aaacagcttg gaggatgcct ctgccccacc aggaggggcc ccaggccctg gcagggcaga
     1381 gaaggaaggg gcttggcttg ggcctcctgg tcctacgcca tcactgccct tgacaaatga
     1441 ttggtgttgg gaaaggacct ggaagtgccc tgggacctgg gaaacattta gctcaagaag
     1501 accttggagc aacatgatcc ctgtcctcag atgtctgggg acagtcattg agcaagcaca
     1561 gggaagtcag cttgttctct ctggcagcgc tggaagacag tcaacctgtg ggtggggggc
     1621 tgcaggggga caggccgcag ccctgcagga ggccgtgctc cgcaatggct gccctaagct
     1681 gcatgggtca gacagcttcc cgtctcggga ggccacaggg cagggaagct gcagagggca
     1741 tgtggccctg ggtagggcag ctgcccttca ctcatgcccc tcccaagcag aggagggaag
     1801 ggctttagtg agaattctag ctctgcctct ttgaccttgc caagtcagga tctgcctctt
     1861 aaaggagcag agaaaaccat cccagatccc ctcgacaccc agccccctac cactgacaga
     1921 gcacaagtga gatctgagtg ttagcccttc agatttgctg actggccttg gcccacccct
     1981 ccctgtgctg cagcttcatt ggcaaaatga atttgatggt atctgtatcc cctgcccagc
     2041 cctaacctgt ttctctgagg ctggcctccc tacggggctg cagcagcaaa gggaagccaa
     2101 gccttagaga agcctcatgg aagggcccag aacatcctgc acccatcagt tactcggaag
     2161 taaggggaca agaagcagct ggaagagagc tgggtgtggg ggctgggagg agtgctggag
     2221 aaatttcccc atcagaaggc ccctcactgg gcagtggagg cagggcagtg tggtgggact
     2281 gactcaacag acatagtttc atctccaccc tgcccttctc aggttgtgtg accccagcca
     2341 catggacacc cgagtctgtg aactaaaggg ctggtccatg gcattaacag tggagggtgt
     2401 ccaggttctt gatgtcttga acaaagaatt gggcaaaatg cacaaagcaa ggaaggaatg
     2461 aagggtttta ctgagaatga aagtatactc cacagcatgg gagagggcct gagcataggg
     2521 actcaagggg cccgttacag aatttttggg agtaaatacc cactagagga ttccattggt
     2581 tacttgaggt acaccctatg taaatggaaa ggatgaagta aatttacaaa ttcatttaca
     2641 gcatataccc tatggggagg atattccctg ttatagctga agcgtgaatt ggccttatgt
     2701 tccctgcctc cagaccctat tttcctgcat caacgggaaa gggtcagatt cactggctca
     2761 gctgtttaac ctgtcctggt gccagcagct ggagctgggt gtcaggacca gcccgcaagc
     2821 tcttccctgc cggaaggacc aggccagtcg ctgtcctttt catgctagag agtggttgtg
     2881 gttgctgact tagcagagaa ggtgcttggc tttcccctta actggagaaa aaactttcta
     2941 agaaccaggc ctggttggca gcagacctag ctttcttggg gtggcaggga ggctaaagca
     3001 tacctcagga cagtcagtgg tgggtccagc ttcggctgga ggttctttct actgaataac
     3061 ttctacgggc tctgtcatta gcaggatttg tataatttga agcagagctg ggcaactgca
     3121 gagcaatggg gaagccagcc cagtgtggtg gcaagacctg ggcaacttgg gaccagcctg
     3181 ggctgtctct tgccagctgt tgttatcaga accaggctct tcacactcag atccttgggc
     3241 cccccatctc agaatgccca gtggttgaaa ggatgaaacc tggaatttaa gtgacttctc
     3301 agtgatgtgt gcccttctct gacggttcct tgttcatccc atgtatttac tgactgcctg
     3361 ctatatatgc agagccaaag agtggggcct ggtcttgaac tatctcctca tctgcccctt
     3421 ctggcacctc cttcctcctg ggctctttcc tctaataccg tcatcctctc tccaacctgg
     3481 ttaatcctgt cctttctgcc ctcaaatggg caccttcaaa gaaacaaata gaactactcc
     3541 actcgctccc tctctccctc cctttactgc cactattgat tgttatagtc acttgctcca
     3601 ggaagtccac ttgctgagtc ttactgcaga cagagcccac cccctgagct gtaaaggccc
     3661 tagggcacat gtttgtccag ctgcctcttg cagctgggat tgttaggtca ctatagcgct
     3721 accaactgca tataccactg tgggagtcgt gctggtggcg gtagtggtca caggtaccag
     3781 gggcagcagt gaaggggtgg ctctaatgcc aagtccagtg accagtgcca gggtgcccag
     3841 tggtggcaac agtggtgttt tcagtgtgat cttggacatt gctcctgtct actcagctgc
     3901 tagtctgtga gctccctgat atcctttaag acagcgtttt ccagcagcgg cactattaac
     3961 gtttggggct aggtaatcgt tgggtgtgtg agtgtgaaga gggctgtcct gtgtgttgta
     4021 ggctatttta gcagcatccc ggcctctccc tgccaggtgc ctgtagcagt cccccagtta
     4081 cgacaaccaa aaatgtgtcc agacattgcc agatgtccac tgggagggaa aacctctctg
     4141 gtccacagcc cttctcctta ttccagtccc acatcttcct ccccttcccc atcactgtcc
     4201 tcagagagat gctgttgaca gctccttgag gtgattctct caggcttgtt gttgtagttc
     4261 tctgctgtca agtctgagct gactctctct tccggattct tctttcctca cctgcccccg
     4321 tttgcatgaa gttttttatg gagctgtttc tattttcttt ttgggcagcc atactctcta
     4381 agacctaaaa gctgaatact cgcccggtta ctacctgata attctcatcg cttatgtttc
     4441 caaaaccaaa ctggttattt ccctctctaa ccccatctct gtgtcaaaca gtggagtaca
     4501 tgcttttggt taatccaatt ggaaggcttc ctagaggaag taatatctga actgaatcct
     4561 gaaagattag gggaagagga agaaaaggac aggtgctgtg ggaaaaaggg gaaagtgtca
     4621 gaggaagtaa atgaaaaacc atatacaaaa ttatcttctg tgacccgtag cacatgccca
     4681 atccatggta gatatcgaaa catagtggtt acccagtcta atccatccct tttctttctt
     4741 tctttctttt ttttcttttt ttttgagaca agtctcactt tgttgcctgc ctggagtgca
     4801 gtggtgcgat ctcggctcac tgcaaccccc gcctcccggg ttcaagtgat tcttctgcct
     4861 cagcctcctg agtagctagg actacaggtg cttgccacca tgaccagcta atttttgtat
     4921 tttcagtaga gatgggtttc accatattgg ccaggatggt ctcgatctct tgacttcgtg
     4981 atctgcctgc ctcggcctcc taaagtgctg ggattacagg cgtaagcaac cgtgcccggc
     5041 tgtccatctc ttttcagatg aagagctcag gttctgagga gtgacttgtc aaaagctgtt
     5101 ctacctctca gagccagccc ttgtcctcct gctagccaga gcaaggtacc acctggaaga
     5161 gatgttcagt tacatgggat ccagggccag agggaaaata tcagtgcttc ctgaggttcg
     5221 ggtccagcca cccttcttcc accatttcta ctgagccttc agttgtaccc cttcagtcca
     5281 cttggcgagg catcacgccc tctgggcagg ctcagtgggg aactatggga gcaggtgctg
     5341 tgtgccacct ctggaggggg tcactgaggt tctgggttgt ggggggtgcc ctgggccaga
     5401 gtgagttgta tgggagttgt tgctgaatcc ccccagagta ccagtcacac accagtgtga
     5461 ggggccttgc aagagccact gggcagcaca gttgaaggtg gcaccttcct gctcagtgct
     5521 gtgtccagag cagggtttag ttttctgtgt ctttcagggt gagactggtg tattctatac
     5581 cagcctccct gtgtgtgaac aatgacgaga acaatgttgt cttgctttcc caaaaaataa
     5641 gacactatct atttctcatt agttatacac gttcattata aaacgtaatt taagcaatac
     5701 tgaaatgcca aaaagaaagt aaaattcact ccaaaagtaa aattcacccc aaatctcact
     5761 actcctgtaa ctatgtctga cagccagctg ttgggtcttc catcgttttt aaccttcagg
     5821 tgagcacaca gatccttatt ttttcttttc ttttcttttt tttttttttt tttttttgag
     5881 acgcagtctc ctgttgccca ggctggagtg caatggcgcg atctctgctc accgtaactt
     5941 ctgcctcccg ggttcaagca agtctcctgc ctcagcttcc tgagtagctg ggattacagg
     6001 catgcaccat cacgcctggc taatttttgt atttttagta gagacggggt ttcaccaagc
     6061 tggccaagct ggtctcgaac tcccgacctc aggcaatccg cccacctcag cctcccaaag
     6121 tgctgggatt acaggcgtga gccaccttgc ccggactctc tttgtatttt ttctttcttt
     6181 tttttgagac agagtcttgc tctgtctccc aggctggagt gcagcgacat gatctcagct
     6241 cactgcagcc tctatctccc aggttccggc agttctccta ccggttagct gggattacag
     6301 gcatgcgcca ccacacccgg ctaatttttg tatttttagt agagacgggg tttcaccatg
     6361 ttggtcaggc tggtctccaa ctcctgacct caaatgatct gcacacctcg gcctcctaaa
     6421 gtgctggaat taccggtgtg agccaccgcg cctggccaga tccttatttt ttcaattgca
     6481 atacagcagt atgcaaggca cttactgtat gccaaagctt atgccgagag ctggctgcca
     6541 gcagctcctc ctgcctcgag gcctttgtcc atgtcatcat ttcccctttg gctgtaacag
     6601 ctgcagttct ctcataattt taggtttcat cttaaatgtc acttcttcag aggcttcttg
     6661 acagcacaag tcagggccct tgttagtttc atcacatcca ttacctttcc ttgatcactt
     6721 gtaccatcat ctgtaattta tttttatgtt taatacgggt gtgggatttc tgattttttt
     6781 ttttgctaga ctggaagctc tcagagggca ggaaccattt gtttccctgc cacagagatg
     6841 ttcaataaat attgtcaatt gaatgtgcaa ataatctcac ttaaccacag ctatgaggga
     6901 tgctatttta tccccatttt agagatgact aaactgaggc ttagaacaat taacccaagg
     6961 tcacagtgaa ttagtggatc catgtgtctg cctccacaca gcctgtgtgt tcttaattat
     7021 tgatcactaa gcaacagctg cctctcacaa actggcagga aacttcaact tttccctttt
     7081 atcaatatat tgtgaacgcc ttttcttgct aataaatata catttgtgtg cgtaa
//
