LOCUS       NM_144719               5456 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 13 (CCDC13), mRNA.
ACCESSION   NM_144719
VERSION     NM_144719.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5456)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 5456)
  AUTHORS   Goldstein,J.I., Jarskog,L.F., Hilliard,C., Alfirevic,A., Duncan,L.,
            Fourches,D., Huang,H., Lek,M., Neale,B.M., Ripke,S., Shianna,K.,
            Szatkiewicz,J.P., Tropsha,A., van den Oord,E.J., Cascorbi,I.,
            Dettling,M., Gazit,E., Goff,D.C., Holden,A.L., Kelly,D.L.,
            Malhotra,A.K., Nielsen,J., Pirmohamed,M., Rujescu,D., Werge,T.,
            Levy,D.L., Josiassen,R.C., Kennedy,J.L., Lieberman,J.A., Daly,M.J.
            and Sullivan,P.F.
  TITLE     Clozapine-induced agranulocytosis is associated with rare HLA-DQB1
            and HLA-B alleles
  JOURNAL   Nat Commun 5, 4757 (2014)
   PUBMED   25187353
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5456)
  AUTHORS   Staples,C.J., Myers,K.N., Beveridge,R.D., Patil,A.A., Howard,A.E.,
            Barone,G., Lee,A.J., Swanton,C., Howell,M., Maslen,S., Skehel,J.M.,
            Boulton,S.J. and Collis,S.J.
  TITLE     Ccdc13 is a novel human centriolar satellite protein required for
            ciliogenesis and genome stability
  JOURNAL   J Cell Sci 127 (Pt 13), 2910-2919 (2014)
   PUBMED   24816561
REFERENCE   4  (bases 1 to 5456)
  AUTHORS   Teumer,A., Holtfreter,B., Volker,U., Petersmann,A., Nauck,M.,
            Biffar,R., Volzke,H., Kroemer,H.K., Meisel,P., Homuth,G. and
            Kocher,T.
  TITLE     Genome-wide association study of chronic periodontitis in a general
            German population
  JOURNAL   J Clin Periodontol 40 (11), 977-985 (2013)
   PUBMED   24024966
REFERENCE   5  (bases 1 to 5456)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK058196.1, BC036050.1, AC006059.3 and BM664398.1.
            
            On May 17, 2019 this sequence version replaced NM_144719.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036050.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000310232.11/ ENSP00000309836.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AK058196.1         1-2
            3-1207              BC036050.1         5-1209
            1208-1208           AC006059.3         28800-28800
            1209-2822           BC036050.1         1211-2824
            2823-2830           BM664398.1         18-25               c
            2831-5456           AC006059.3         60093-62718
FEATURES             Location/Qualifiers
     source          1..5456
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p22.1"
     gene            1..5456
                     /gene="CCDC13"
                     /note="coiled-coil domain containing 13"
                     /db_xref="GeneID:152206"
                     /db_xref="HGNC:HGNC:26358"
     exon            1..78
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            79..305
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..2232
                     /gene="CCDC13"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 13"
                     /protein_id="NP_653320.3"
                     /db_xref="CCDS:CCDS2705.1"
                     /db_xref="GeneID:152206"
                     /db_xref="HGNC:HGNC:26358"
                     /translation="MAADESSQNTLRLQFKAMQEMQHKRLQKQMEKKREKELSLKSRA
                     DDQEEPLEVSDGLSLLHAGEPNSKNSFEKRVLEDEIEHLRNELRETVDENGRLYKLLK
                     ERDFEIKHLKKKIEEDRFAFTGTAGVAGDVVATKIVELSKKNRLLMAESEGAKTRVKQ
                     LTNRIQELERELQTALTRLSAKGATDAGAKPPRAQMGDRALLETPEVKALQDRLVATN
                     LKMSDLRNQIQSVKQELRMAQKVLAREVGEDINVQQLLSSPGTWRGRAQQILVLQSKV
                     QELEKQLGQARSQSAGTASDELSVYPDPRKLSAQEKNLLRIRSLEREKQEGLEKLASE
                     RDVLQRELEELKKKFEGMRSRNKLLSSEMKTLKSQMGTLVEKGRHDDELIDALMDQLK
                     QLQEILGSLSLQEEKTRVSQHHLDQQLNSEAQRSNSLVAQLQAMVAEREAKVRQLEME
                     IGQLNVHYLRNKGVGEGSSGREVSPAYTQFLEDPGLTKSPASAGDHVGRLGSSRSVTS
                     LGHTLVESALTRPSLPSPHRTSPRFSDSPEQKGWQAQVSEIKALWQAAEVERDRLTEF
                     VTVLQKRVEESNSKLLESERKLQEERHRTVVLEQHLEKIRLEPGKASASQRAAPRTKT
                     GLPTSNNRHNPTGSEKKDPSFAQLSDVPVESQMEELTTRLAIQVEENEMLKAALGSAL
                     RGKEEDFRMYHEILGQVKSVFLQALRQQKTGKQ"
     exon            306..454
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            455..597
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            598..687
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            688..804
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            805..909
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1071
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1248
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1455
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1595
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1679
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1802
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..1957
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2072
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     exon            2073..5456
                     /gene="CCDC13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2806..2811
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC13"
                     /note="hexamer: AATAAG"
     polyA_site      2825
                     /gene="CCDC13"
                     /note="major polyA site"
ORIGIN      
        1 agggcagcgc gtgtcggcgt ccggaggagg tgacctagcc gccgcggtcc tagaagggag
       61 aagtggagag agaccgctgg caggatggca gcagatgaaa gctcacagaa cactttgcgg
      121 ctccagttca aggcaatgca ggagatgcag cacaaacggt tacagaagca gatggagaaa
      181 aagagggaaa aagaactgag cctcaaaagc agagctgacg accaagagga gcccttggag
      241 gtttcagatg gcctcagcct tctccacgca ggggagccaa actcgaaaaa tagctttgag
      301 aagagggtgc ttgaagatga gattgaacac cttcgaaatg agctcaggga aacggtggac
      361 gagaacgggc gattgtataa gctgctgaag gaaagggact ttgaaatcaa acacctcaaa
      421 aagaaaatag aagaggacag atttgccttc acagggacag ccggtgtagc cggagacgtg
      481 gtcgccacca aaattgtgga gctatcaaaa aagaaccggc tgttgatggc agaatcagag
      541 ggtgcaaaaa ccagggtgaa gcagctgacc aatcgcatcc aggagctgga gcgggaactg
      601 cagacagccc tgaccaggct gtcagccaag ggggccaccg acgcaggagc caagccaccg
      661 agggcccaga tgggagacag agcattgctg gagaccccag aggtgaaggc cctgcaggac
      721 aggctggtgg ccaccaactt gaagatgagt gacctccgaa accagatcca gtctgtgaag
      781 caggagctgc ggatggcaca gaaggttttg gccagagagg ttggggaaga catcaacgtt
      841 cagcagctcc tatcttcgcc agggacctgg aggggtcggg ctcaacaaat tcttgttttg
      901 cagagcaagg ttcaagagct tgagaagcaa ttgggccagg cccggagcca gtctgcggga
      961 acagccagtg atgagttgtc tgtctatcca gacccaagga agctgtcggc acaggagaaa
     1021 aacctgctga ggatccgcag cctggaaagg gaaaaacagg aaggcttgga gaaacttgcc
     1081 agtgaacggg atgtcctcca gagagagctt gaagagctaa aaaagaagtt cgagggcatg
     1141 aggtctcgga acaagctgct gtcaagtgag atgaagaccc tcaagagtca gatgggaacc
     1201 ctggtggaga agggccggca tgatgacgag ctcatcgacg ccctcatgga ccagctgaag
     1261 cagctacagg agatcctagg cagcctgagt ctgcaggagg agaaaacgcg agtgtcccag
     1321 caccacctgg accagcaact gaacagcgag gctcagcgga gcaacagcct agtcgcccag
     1381 ctgcaggcca tggtagctga gcgggaggcc aaagtgcgac agctggagat ggagatcgga
     1441 caactcaatg tgcactatct tcggaataaa ggagtgggtg aggggtccag tggccgcgag
     1501 gtcagccctg cctataccca gttcctggag gacccaggcc tgaccaagtc cccggcctca
     1561 gcaggcgatc atgttggcag gcttggatct tctcgctctg tgaccagcct gggccacaca
     1621 ctggtggaat ctgctctcac gaggccttcc ctgcccagtc cccacaggac ctcacctagg
     1681 ttctcggact ccccagaaca aaaaggctgg caggcacaag tgtcagagat caaggccctc
     1741 tggcaggctg ccgaggtgga gcgtgaccgg ctcaccgagt ttgtcactgt cctgcagaaa
     1801 cgggtggagg agagcaacag caagctcctg gagtcagaga ggaagctgca ggaggagcga
     1861 caccgcaccg tggtgctgga gcaacatctg gagaagatac gcctggagcc agggaaggca
     1921 tcagcctccc agagagcagc tcccaggacc aaaacaggtc tgcccacctc taacaacagg
     1981 cacaacccaa ccgggagcga gaagaaggac ccatcctttg cccagctctc cgatgtgccc
     2041 gtggaatccc aaatggaaga gctgacaacc aggctggcca tccaggtgga ggagaatgaa
     2101 atgctaaagg ctgccctggg cagtgccctg cggggaaagg aggaggactt ccggatgtac
     2161 catgagatcc tgggccaggt gaaaagtgtc ttcctgcagg ccctgcggca gcagaagaca
     2221 ggcaagcaat aggatgacag cccagtgtcg gcctggccgg gtgggcagcc tcaggtcttg
     2281 agaggataag actctgtctg aggactccat ctgctccggg aagccagccc agggcagcca
     2341 gctcaaccac ttctaccaga agaggctcct taaggatgac caaaaccaat gtctcaggcc
     2401 aggaaggcag aagagaagcc ctggtgggac actgcaggag accctgggct ggctgggtta
     2461 cagcagcagg gaggcccagc agcccactgg cagaggcgag agctctggga tggcaaggcg
     2521 gctgtgaatg gacagatgca gtccctcggg caggtgttca tcgccctcat cctaggtact
     2581 agccctggat gtccccatgg cttcacacac agaagagccc ttggttaccc taagtgggca
     2641 tatcccccat gccactcagc cctgccctat cccctcaccc ccatcccggc tccatctgta
     2701 gccgtccaca ccctacacag acttggggca ctatgctctc aaccagtttg tcagcccact
     2761 cctcaggaca cttcctcagg tgcagaccct tggacttgta ataataataa gtattttcat
     2821 aatcactgca gctcccagtg agtgagcatc tactgtggca acctgacccc attcagtcct
     2881 ctaatgaccc aggggtttgt tgtcttattt gacagatgaa gaaactgagg ttcacagaaa
     2941 gaagctgagc taatatttaa ctgcagtctg cctgacccca aaaccagggt cttgccgttc
     3001 agagattacc cagggtaggc gcacccaccc accactgaac aaccccaccc ctaggcagca
     3061 gctccaagag gcatctttgt ttgctcacca agactgctga tggatgctgg tggcagaggg
     3121 ccgaggtggg gctcagctgg agcttcaggc agaagggttt tgaggtagtg gctccagtca
     3181 aaggtacagt gcacctccct cgccatggtg aacttggagg gatgctgcag gggcacccta
     3241 agatccgcag gcctctatga ctgtcagtgt tgccctttct cagctgtaac tatgcactta
     3301 tagctacagg aaggagtggc cccaaggagg gtcactcata gccacacacc ccaactccga
     3361 caccctggcc acacaggtgc acccacagcc ccacacaaag atgcagatgc acacacatac
     3421 ctcaattcag gagcatgcaa ctgtacgtgc acacaggcac ctccatgtgt gcacactcat
     3481 ggacacacag gtgcagatga gcacacacat gtggatgtgg acacacattc ccacacgtga
     3541 agacatagcc acttgtgtgt tgcttgtgca gtgatgcaca aatgcaggtg cacatactgt
     3601 gaaaacaccc ccttccccag gaaaagccac tggggctcct gcgagcatct tgtcagctcc
     3661 ttccttggaa aagccactgc ggctcctggg accctgtctt ctcagcccct tccttgggga
     3721 tggggctatg gagggaccct agctggcccc cactcctcag ggagcccctg accctgcatg
     3781 gggtcacacg gatctagaga tcccacagca agttagagca aaggccaccg ggatgaactg
     3841 atgattctgg tggggtccta agggtctctg ggaaggaaga gtttttctct ggttccttgt
     3901 gaaggaaaac ggccaggcag agagccagga gagagagggt ctgtgcttgg aggggacagt
     3961 gtgtgacagc gaggggtggg ctggatgtag agtctgaaca cagaggagtc agcaccttct
     4021 cctgcaggcc ctgaggagct ccagagggtg atctgagtat gaggggtaca ggctctggcc
     4081 tcagtgcagt cccagggagt gagaagcagg cataggatca gccatccttc ctcaagatca
     4141 cctcagggaa gtgcagagat ggtgtgaccc acactccagc cacttcaggg tggttctgct
     4201 gcccttcctg ggctatgcct gagaaaggaa ggagcattag gtcatggagt ctggacaggt
     4261 ggggctgcct ggggcatact tctctcccca cttaccagct gtgtggcctt gggcaagtta
     4321 tttaacctct ctgatcctcc acattctcat ctataaaatg cagacaataa tagaatcctc
     4381 cctcaggggg ctgttattaa tatgtatgtc aaagaataac ccaaagacgt ttcactaatt
     4441 attagctctc tgtttatttc tgtacaagga acatgtatct atagactgat ttcaacaaga
     4501 gttatataag agagagggga aagaaaaact gcagacaggc aggcacagga aatcttgttt
     4561 gcacattttt gggtaaactg atttgctggt gtcttgcttt ggccaactct gtatataaag
     4621 atgagtgttt cagctttcag attccacggg caaccttgac agcattgctg tggtgccatg
     4681 tgcgggagtg cctgtcatgt ctgctggcac ctaccaccgg gcacctcccc acccctagct
     4741 tggttagatc aggtctgctc cattccctca ttggaaccct ctgcagggtt cactgagata
     4801 aagtgtccat tgcttacagc agctgctcgc acacagtaag cgcttaataa ttattcgctc
     4861 ttagtgttcc ctccatttgt tcaaccagaa cttgttgagc agttcctctg ccccaggcac
     4921 agaggtgccg aggtgaggca aacacagtcc ctggcctcca ggaactctca gatcagctga
     4981 ggagagagac agactggtca caggtcacca ttccatccag ccagtcggcc accaggcagt
     5041 cagtgagtgc caacagcatg ccagcctctc caggcctggg agggacctag aggtgaatct
     5101 gacttgcttc ctcctttcag ggagtttcca gtccaatcag aggtgtggga aacgccatga
     5161 tggagctggg tggggaagga tgcaggaccg ggctgcagca ccacagggct tcccccacca
     5221 tccccacccc atccctgtgg cagttcccaa gttcccaacc tccttgatca gatctgggta
     5281 gagagggggc ttcacatctc cctgaggcaa aggagcaagg aggagtaaag ggaaggtggg
     5341 gagagcctgg gagaaggatt ttcaagggaa ggaggtcatc aaaggggtca aagataggga
     5401 ccctgagaaa cctaacttag gtgggccagg tgcacagcca ggcagctggt ctgtcc
//
