LOCUS       NM_138771               2470 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens coiled-coil domain containing 126 (CCDC126), mRNA.
ACCESSION   NM_138771
VERSION     NM_138771.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2470)
  AUTHORS   Chiang,C.Y., Ching,Y.H., Chang,T.Y., Hu,L.S., Yong,Y.S., Keak,P.Y.,
            Mustika,I., Lin,M.D. and Liao,B.Y.
  TITLE     Novel eye genes systematically discovered through an integrated
            analysis of mouse transcriptomes and phenome
  JOURNAL   Comput Struct Biotechnol J 18, 73-82 (2019)
   PUBMED   31934309
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2470)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2470)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL598772.1, AY358713.1 and AC006026.2.
            
            On Nov 23, 2018 this sequence version replaced NM_138771.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163658.61301.1,
                                           SRR3476690.953574.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000307471.8/ ENSP00000304355.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AL598772.1         5-34
            31-1113             AY358713.1         1-1083
            1114-2470           AC006026.2         84613-85969
FEATURES             Location/Qualifiers
     source          1..2470
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p15.3"
     gene            1..2470
                     /gene="CCDC126"
                     /note="coiled-coil domain containing 126"
                     /db_xref="GeneID:90693"
                     /db_xref="HGNC:HGNC:22398"
     exon            1..224
                     /gene="CCDC126"
                     /inference="alignment:Splign:2.1.0"
     exon            225..309
                     /gene="CCDC126"
                     /inference="alignment:Splign:2.1.0"
     exon            310..692
                     /gene="CCDC126"
                     /inference="alignment:Splign:2.1.0"
     CDS             455..877
                     /gene="CCDC126"
                     /note="coiled-coil domain-containing protein 126"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 126
                     precursor"
                     /protein_id="NP_620126.2"
                     /db_xref="CCDS:CCDS5384.1"
                     /db_xref="GeneID:90693"
                     /db_xref="HGNC:HGNC:22398"
                     /translation="MFFTISRKNMSQKLSLLLLVFGLIWGLMLLHYTFQQPRHQSSVK
                     LREQILDLSKRYVKALAEENKNTVDVENGASMAGYADLKRTIAVLLDDILQRLVKLEN
                     KVDYIVVNGSAANTTNGTSGNLVPVTTNKRTNVSGSIR"
     exon            693..2470
                     /gene="CCDC126"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2447..2452
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CCDC126"
                     /note="hexamer: AATAAA"
     polyA_site      2470
                     /gene="CCDC126"
                     /note="major polyA site"
ORIGIN      
        1 gaggcggagc ggaagccgag tgcgagggac gagcggagta aaatctccac aagctgggaa
       61 caaacctcgt cccaactccc acccaccggc gtttctccag ctcgatctgg aggctgcttc
      121 gccagtgtgg gacgcagctg acgcccgctt attagctctc gctgcgtcgc cccggctcag
      181 aagctccgtg gcggcggcga ccgtgacgag aagcccacgg ccagctcagt tctcttctac
      241 tttgggagag agagaaagtc agatgcccct tttaaactcc ctcttcaaaa ctcatctcct
      301 gggtgactga gttaatagag tggatacaac cttgctgaag atgaagaata tacaatattg
      361 aggatatttt tttctttttt ttttcaagtc ttgatttgtg gcttacctca agttaccatt
      421 tttcagtcaa gtctgtttgt ttgcttcttc agaaatgttt tttacaatct caagaaaaaa
      481 tatgtcccag aaattgagtt tactgttgct tgtatttgga ctcatttggg gattgatgtt
      541 actgcactat acttttcaac aaccaagaca tcaaagcagt gtcaagttac gtgagcaaat
      601 actagactta agcaaaagat atgttaaagc tctagcagag gaaaataaga acacagtgga
      661 tgtcgagaac ggtgcttcta tggcaggata tgcggatctg aaaagaacaa ttgctgtcct
      721 tctggatgac attttgcaac gattggtgaa gctggagaac aaagttgact atattgttgt
      781 gaatggctca gcagccaaca ccaccaatgg tactagtggg aatttggtgc cagtaaccac
      841 aaataaaaga acgaatgtct cgggcagtat cagatagcag ttgaaaatca ccttgtgctg
      901 ctccatccac tgtggattat atcctatggc agaaaagctt tataattgct ggcttaggac
      961 agagcaatac tttacaataa aagctctaca cattttcaag gagtatgctg gattcatgga
     1021 actctaattc tgtacataaa aattttaaag ttatttgttt gctttcaggc aagtctgttc
     1081 aatgctgtac tatgtcctta aagagaattt ggtaatttgg ttgatgtggt aagcagatag
     1141 gtgagttttg tataaatctt ttgtgtttga gatcaagctg aaatgaaaac actgaaaaac
     1201 atggattcat ttctataaca catttattta agtatataac acgttttttg gacaagtgaa
     1261 gaatgtttaa tcattctgtc atttgttctc aatagatgta actgttagac tacggctatt
     1321 tgaaaaaatg tgcttattgt actatatttt gttattccaa ttatgagcag agaaaggaaa
     1381 tataatgttg aaaataatgt tttgaaatca tgacccaaag aatgtattga tttgcactat
     1441 ccttcagaat aactgaaggt taattattgt atatttttaa aaattacact tataagagta
     1501 taatcttgaa atgggtagca gccactgtcc attacctatc gtaaacattg gggcaattta
     1561 ataacagcat taaaatagtt gtaaactcta atcttatact tattgaagaa taaaagatat
     1621 ttttatgatg agagtaacaa taaagtattc atgatttttc acatacatga atgttcattt
     1681 aaaagtttaa tcctttgagt gtctatgcta tcaggaaagc acattatttc catatttggg
     1741 ttaattttgc ttttattata ttggtctagg aggaagggac tttggagaat ggaactcttg
     1801 aggactttag ccaggtgtat ataataaagg tacttttgtg ctgcattaaa ttgcttggaa
     1861 aatgttaaca ttatattata taagagtatc ctttatgaaa ttttgaattt gtataacaga
     1921 tgcattagat attcatttta tataatggcc acttaaaata agaacattta aaatataaac
     1981 tatgaagatt gactatcttt tcaggaaaaa agctgtatat agcacaggga accctaatct
     2041 tgggtaattc tagtataaaa caaattatac ttttatttaa atttcccttg tagcaaatct
     2101 aattgccaca tggtgcccta tatttcatag tatttattct ctatagtaac tgcttaagtg
     2161 cagctagctt ctagatttag actatataga atttagatat tgtattgttc gtcattataa
     2221 tatgctacca catgtagcaa taattacaat attttattaa aataaatatg tgaaatattg
     2281 tttcatgaaa gacagatttc caaatctctc ttctcttctc tgtactgtct acctttatgt
     2341 gaagaaatta attatatgcc attgccaggt agaagtttgg aataattgtt tagtctctcc
     2401 tattagatgt ggacattttt gtttttgttt ttgttttcag ggatgaaata aaatatatta
     2461 tttctaccta
//
