LOCUS       NM_001385503            3727 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens caprin family member 2 (CAPRIN2), transcript variant
            15, mRNA.
ACCESSION   NM_001385503 XM_017019853
VERSION     NM_001385503.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3727)
  AUTHORS   Ma,B., Zhang,W., Wang,X., Jiang,H., Tang,L., Yang,W., Kang,Q. and
            Cao,J.
  TITLE     Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the
            Susceptibility to High Myopia-Induced Cataract in Han Chinese
            Population
  JOURNAL   Med Sci Monit 29, e937702 (2023)
   PUBMED   36710479
  REMARK    GeneRIF: Polymorphisms in TRIB2 and CAPRIN2 Genes Contribute to the
            Susceptibility to High Myopia-Induced Cataract in Han Chinese
            Population.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3727)
  AUTHORS   Zheng,Y., Zeng,J., Xia,H., Wang,X., Chen,H., Huang,L. and Zeng,C.
  TITLE     Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B antisense
            RNA 1 induces the proliferation and migration of colorectal cancer
            by miR-378b/CAPRIN2 axis
  JOURNAL   Bioengineered 12 (1), 5476-5490 (2021)
   PUBMED   34511033
  REMARK    GeneRIF: Upregulated lncRNA Cyclin-dependent kinase inhibitor 2B
            antisense RNA 1 induces the proliferation and migration of
            colorectal cancer by miR-378b/CAPRIN2 axis.
REFERENCE   3  (bases 1 to 3727)
  AUTHORS   Ai,Y., Wu,S., Zou,C. and Wei,H.
  TITLE     LINC00941 promotes oral squamous cell carcinoma progression via
            activating CAPRIN2 and canonical WNT/beta-catenin signaling pathway
  JOURNAL   J Cell Mol Med 24 (18), 10512-10524 (2020)
   PUBMED   32691935
  REMARK    GeneRIF: LINC00941 promotes oral squamous cell carcinoma
            progression via activating CAPRIN2 and canonical WNT/beta-catenin
            signaling pathway.
REFERENCE   4  (bases 1 to 3727)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 3727)
  AUTHORS   Wang,X., Jia,Y., Fei,C., Song,X. and Li,L.
  TITLE     Activation/Proliferation-associated Protein 2 (Caprin-2) Positively
            Regulates CDK14/Cyclin Y-mediated Lipoprotein Receptor-related
            Protein 5 and 6 (LRP5/6) Constitutive Phosphorylation
  JOURNAL   J Biol Chem 291 (51), 26427-26434 (2016)
   PUBMED   27821587
  REMARK    GeneRIF: findings revealed an unrecognized role of Caprin-2 in
            facilitating LRP5/6 constitutive phosphorylation at G2/M through
            forming a quaternary complex with CDK14, Cyclin Y, and LRP5/6.
REFERENCE   6  (bases 1 to 3727)
  AUTHORS   Shiina,N. and Tokunaga,M.
  TITLE     RNA granule protein 140 (RNG140), a paralog of RNG105 localized to
            distinct RNA granules in neuronal dendrites in the adult vertebrate
            brain
  JOURNAL   J Biol Chem 285 (31), 24260-24269 (2010)
   PUBMED   20516077
REFERENCE   7  (bases 1 to 3727)
  AUTHORS   Ding,Y., Xi,Y., Chen,T., Wang,J.Y., Tao,D.L., Wu,Z.L., Li,Y.P.,
            Li,C., Zeng,R. and Li,L.
  TITLE     Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6
            phosphorylation
  JOURNAL   J Cell Biol 182 (5), 865-872 (2008)
   PUBMED   18762581
  REMARK    GeneRIF: Caprin-2 promotes activation of the canonical Wnt
            signaling pathway by regulating LRP5/6 phosphorylation.
REFERENCE   8  (bases 1 to 3727)
  AUTHORS   Tao,W.A., Wollscheid,B., O'Brien,R., Eng,J.K., Li,X.J.,
            Bodenmiller,B., Watts,J.D., Hood,L. and Aebersold,R.
  TITLE     Quantitative phosphoproteome analysis using a dendrimer conjugation
            chemistry and tandem mass spectrometry
  JOURNAL   Nat Methods 2 (8), 591-598 (2005)
   PUBMED   16094384
REFERENCE   9  (bases 1 to 3727)
  AUTHORS   Grill,B., Wilson,G.M., Zhang,K.X., Wang,B., Doyonnas,R.,
            Quadroni,M. and Schrader,J.W.
  TITLE     Activation/division of lymphocytes results in increased levels of
            cytoplasmic activation/proliferation-associated protein-1:
            prototype of a new family of proteins
  JOURNAL   J Immunol 172 (4), 2389-2400 (2004)
   PUBMED   14764709
REFERENCE   10 (bases 1 to 3727)
  AUTHORS   Aerbajinai,W., Lee,Y.T., Wojda,U., Barr,V.A. and Miller,J.L.
  TITLE     Cloning and characterization of a gene expressed during terminal
            differentiation that encodes a novel inhibitor of growth
  JOURNAL   J Biol Chem 279 (3), 1916-1921 (2004)
   PUBMED   14593112
  REMARK    GeneRIF: regulated expression of EEG-1 is involved in the
            orchestrated regulation of growth that occurs as erythroblasts
            shift from a highly proliferative state toward their terminal phase
            of differentiation.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC010198.8.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jul 20, 2020 this sequence version replaced XM_017019853.1.
            
            Summary: The protein encoded by this gene may regulate the
            transport of mRNA. It may play a role in the differentiation of
            erythroblasts. Multiple transcript variants encoding different
            isoforms have been found for this gene. [provided by RefSeq, Feb
            2016].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.202881.1,
                                           SRR14038196.2944411.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000695402.1/ ENSP00000511883.1
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-201               AC010198.8         140508-140708
            202-417             AC010198.8         141900-142115
            418-480             AC010198.8         144326-144388
            481-567             AC010198.8         154353-154439
            568-806             AC010198.8         160253-160491
            807-889             AC010198.8         161748-161830
            890-1057            AC010198.8         163949-164116
            1058-1101           AC010198.8         165177-165220
            1102-1779           AC010198.8         166134-166811
            1780-1902           AC010198.8         169371-169493
            1903-1984           AC010198.8         171008-171089
            1985-2040           AC010198.8         172145-172200
            2041-2145           AC010198.8         174544-174648
            2146-2292           AC010198.8         176234-176380
            2293-2461           AC010198.8         178783-178951
            2462-2644           AC010198.8         180318-180500
            2645-2745           AC010198.8         181574-181674
            2746-2809           AC010198.8         183830-183893
            2810-3727           AC010198.8         184989-185906
FEATURES             Location/Qualifiers
     source          1..3727
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p11.21"
     gene            1..3727
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /note="caprin family member 2"
                     /db_xref="GeneID:65981"
                     /db_xref="HGNC:HGNC:21259"
                     /db_xref="MIM:610375"
     exon            1..201
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            202..417
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..3378
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /note="isoform 12 is encoded by transcript variant 15; RNA
                     granule protein 140; C1q domain-containing protein 1;
                     gastric cancer multidrug resistance-associated protein;
                     cytoplasmic activation/proliferation-associated protein 2"
                     /codon_start=1
                     /product="caprin-2 isoform 12"
                     /protein_id="NP_001372432.1"
                     /db_xref="CCDS:CCDS91677.1"
                     /db_xref="GeneID:65981"
                     /db_xref="HGNC:HGNC:21259"
                     /db_xref="MIM:610375"
                     /translation="MKSAKPQVNHSQHGESQRALSPLQSTLSSAASPSQAYETYIENG
                     LICLKHKIRNIEKKKLKLEDYKDRLKSGEHLNPDQLEAVEKYEEVLHNLEFAKELQKT
                     FSGLSLDLLKAQKKAQRREHMLKLEAEKKKLRTILQVQYVLQNLTQEHVQKDFKGGLN
                     GAVYLPSKELDYLIKFSKLTCPERNESLSVEDQMEQSSLYFWDLLEGSEKAVVGTTYK
                     HLKDLLSKLLNSGYFESIPVPKNAKEKEVPLEEEMLIQSEKKTQLSKTESVKESESLM
                     EFAQPEIQPQEFLNRRYMTEVDYSNKQGEEQPWEADYARKPNLPKRWDMLTEPDGQEK
                     KQESFKSWEASGKHQEVSKPAVSLEQRKQDTSKLRSTLPEEQKKQEISKSKPSPSQWK
                     QDTPKSKAGYVQEEQKKQETPKLWPVQLQKEQDPKKQTPKSWTPSMQSEQNTTKSWTT
                     PMCEEQDSKQPETPKSWENNVESQKHSLTSQSQISPKSWGVATASLIPNDQLLPRKLN
                     TEPKDVPKPVHQPVGSSSTLPKDPVLRKEKLQDLMTQIQGTCNFMQESVLDFDKPSSA
                     IPTSQPPSATPGSPVASKEQNLSSQSDFLQEPLQATSSPVTCSSNACLVTTDQASSGS
                     ETEFMTSETPEAAIPPGKQPSSLASPNPPMAKGSEQGFQSPPASSSSVTINTAPFQAM
                     QTVFNVNAPLPPRKEQEIKESPYSPGYNQSFTTASTQTPPQCQLPSIHVEQTVHSQET
                     ANYHPDGTIQVSNGSLAFYPAQTNVFPRPTQPFVNSRGSVRGCTRGGRLITNSYRSPG
                     GYKGFDTYRGLPSISNGNYSQLQFQAREYSGAPYSQRDNFQQCYKRGGTSGGPRANSR
                     AGWSDSSQVSSPERDNETFNSGDSGQGDSRSMTPVDVPVTNPAATILPVHVYPLPQQM
                     RVAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFIFHMLKL
                     AVNVPLYVNLMKNEEVLVSAYANDGAPDHETASNHAILQLFQGDQIWLRLHRGAIYGS
                     SWKYSTFSGYLLYQD"
     exon            418..480
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            481..567
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            568..806
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            807..889
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1057
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1101
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1779
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            1780..1902
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..1984
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2040
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2145
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2292
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2293..2461
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2462..2644
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2645..2745
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2746..2809
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     exon            2810..3727
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3709..3714
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /note="hexamer: AATAAA"
     polyA_site      3727
                     /gene="CAPRIN2"
                     /gene_synonym="C1QDC1; EEG-1; EEG1; RNG140"
                     /note="major polyA site"
ORIGIN      
        1 ctgggcgcga gcggctgagt cggctgggtc tctggcgccg cagaggccgc gggcgaggac
       61 cgggagggga gagggaggag acaggaggag gagacgcgag tgcggggtgg cgccggtcca
      121 cctccgcagc gctcctgcct cccccaggct ttggaaggcg ggcccgggct gcggcagcgg
      181 cggcctcggc tgcctgggga gtcaccttca ggccattcag aggaggaaag agaggggaat
      241 atgaagtcag ccaagcccca agtgaaccac agtcagcatg gggaaagcca gcgggccttg
      301 agccccctgc agtctactct gagttctgct gcatctcctt cccaagcgta tgagacctat
      361 attgaaaatg gactcatatg ccttaaacac aaaattagaa acatcgagaa aaagaagctc
      421 aaactggagg attataagga tcgcctgaaa agtggagagc atcttaatcc agaccagttg
      481 gaagctgtag agaaatatga agaagtgcta cataatttgg aatttgccaa ggagcttcaa
      541 aaaacctttt ctgggttgag cctagatcta ctaaaagcgc aaaagaaggc ccagagaagg
      601 gagcacatgc taaaacttga ggctgagaag aaaaagcttc gaactatact tcaagttcag
      661 tatgtattgc agaacttgac acaggagcac gtacaaaaag acttcaaagg gggtttgaat
      721 ggtgcagtgt atttgccttc aaaagaactt gactacctca ttaagttttc aaaactgacc
      781 tgccctgaaa gaaatgaaag tctgagtgtt gaagaccaga tggagcagtc atccttgtac
      841 ttttgggacc ttttggaagg tagtgagaaa gcagtggtag gaacgacata caaacacttg
      901 aaggatctac tgtctaaatt gctgaactca ggctattttg aaagtatccc agttcccaaa
      961 aatgccaagg aaaaggaagt accactggag gaagaaatgc taatacaatc agagaaaaaa
     1021 acacaattat cgaagactga atctgtcaaa gagtcagagt ctctaatgga atttgcccag
     1081 ccagagatac aaccacaaga gtttcttaac agacgctata tgacagaagt agattattca
     1141 aacaaacaag gcgaagagca accttgggaa gcagattatg ctagaaaacc aaatctccca
     1201 aaacgttggg atatgcttac tgaaccagat ggtcaagaga agaaacagga gtcctttaag
     1261 tcctgggagg cttctggtaa gcaccaggag gtatccaagc ctgcagtttc cttagaacag
     1321 aggaaacaag acacctcaaa actcaggtct actctgccgg aagagcagaa gaagcaggag
     1381 atctccaaat ccaagccatc tcctagccag tggaagcaag atacacctaa atccaaagca
     1441 gggtatgttc aagaggaaca aaagaaacag gagacaccaa agctgtggcc agttcagctg
     1501 cagaaagaac aagatccaaa gaagcaaact ccaaagtctt ggacaccttc catgcagagc
     1561 gaacagaaca ccaccaagtc atggaccact cccatgtgtg aagaacagga ttcaaaacag
     1621 ccagagactc caaaatcctg ggaaaacaat gttgagagtc aaaaacactc tttaacatca
     1681 cagtcacaga tttctccaaa gtcctgggga gtagctacag caagcctcat accaaatgac
     1741 cagctgctgc ccaggaagtt gaacacagaa cccaaagatg tgcctaagcc tgtgcatcag
     1801 cctgtaggtt cttcctctac ccttccgaag gatccagtat tgaggaaaga aaaactgcag
     1861 gatctgatga ctcagattca aggaacttgt aactttatgc aagagtctgt tcttgacttt
     1921 gacaaacctt caagtgcaat tccaacgtca caaccgcctt cagctactcc aggtagcccc
     1981 gtagcatcta aagaacaaaa tctgtccagt caaagtgatt ttcttcaaga gccgttacag
     2041 gctacttctt ctccagttac ttgtagctca aatgcttgct tggttactac cgatcaggct
     2101 tcttctggat ctgaaacaga gtttatgacc tcagagactc ctgaggcagc aattccccca
     2161 ggcaagcaac cgtcttcact agcttctcca aatcctccca tggcaaaggg ctctgaacag
     2221 ggcttccagt cacctccagc aagtagtagt tcagtaacca ttaacacagc accctttcaa
     2281 gccatgcaga cagtatttaa cgttaatgca cctctgcctc cacgaaaaga acaagaaata
     2341 aaagaatccc cttattcacc tggctacaat caaagtttta ccacagcaag tacacaaaca
     2401 ccaccccagt gccaactgcc atctatacat gtagaacaaa ctgtccattc tcaagagact
     2461 gcaaattatc atcctgatgg aactattcaa gtaagcaatg gtagccttgc cttttaccca
     2521 gcacagacga atgtgtttcc cagacctact cagccatttg tcaatagccg gggatctgtt
     2581 agaggatgta ctcgtggtgg gagattaata accaattcct atcggtcccc tggtggttat
     2641 aaaggttttg atacttatag aggactccct tcaatttcca atggaaatta tagccagctg
     2701 cagttccaag ctagagagta ttctggagca ccttattccc aaagggataa tttccagcag
     2761 tgttataagc gaggagggac atctggtggt ccacgagcaa attcgagagc agggtggagt
     2821 gattcttctc aggtgagcag cccagaaaga gacaacgaaa cctttaacag tggtgactct
     2881 ggacaaggag actcccgtag catgacccct gtggatgtgc cagtgacaaa tccagcagcc
     2941 accatactgc cagtacacgt ctaccctctg cctcagcaga tgcgagttgc cttctcagca
     3001 gccagaacct ctaatctggc ccctggaact ttagaccaac ctattgtgtt tgatcttctt
     3061 ctgaacaact taggagaaac ttttgatctt cagcttggta gatttaattg cccagtgaat
     3121 ggcacttacg ttttcatttt tcacatgcta aagctggcag tgaatgtgcc actgtatgtc
     3181 aacctcatga agaatgaaga ggtcttggta tcagcctatg ccaatgatgg tgctccagac
     3241 catgaaactg ctagcaatca tgcaattctt cagctcttcc agggagacca gatatggtta
     3301 cgtctgcaca ggggagcaat ttatggaagt agctggaaat attctacgtt ttcaggctat
     3361 cttctttatc aagattgaaa gtcagtacag tattgacaat aaaaggatgg tgttctaatt
     3421 agtgggattg aaggaaaagt agtctttgcc ctcatgactg attggtttag gaaaatgttt
     3481 ttgttcctag agggaggagg tccttacttt tttgttttcc ttcctgaggt gaaaaatcaa
     3541 gctgaatgac aattagcact aatctggcac tttataaatt gtgatgtagc ctcgctagtc
     3601 aagctgtgaa tgtatattgt ttgcacttaa tccttaactg tattaacgtt cagcttacta
     3661 aactgactgc ctcaagtcca ggcaagttac aatgccttgt tgtgcctcaa taaaaaagtt
     3721 acatgca
//
