LOCUS       XM_047431344            2046 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens calpain 2 (CAPN2), transcript variant X1,
            mRNA.
ACCESSION   XM_047431344
VERSION     XM_047431344.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2046
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2046
                     /gene="CAPN2"
                     /gene_synonym="CANP2; CANPL2; CANPml; mCANP"
                     /note="calpain 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 85 ESTs, 251 long SRA
                     reads, and 91% coverage of the annotated genomic feature
                     by RNAseq alignments, including 99 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:824"
                     /db_xref="HGNC:HGNC:1479"
                     /db_xref="MIM:114230"
     CDS             103..1446
                     /gene="CAPN2"
                     /gene_synonym="CANP2; CANPL2; CANPml; mCANP"
                     /codon_start=1
                     /product="calpain-2 catalytic subunit isoform X1"
                     /protein_id="XP_047287300.1"
                     /db_xref="GeneID:824"
                     /db_xref="HGNC:HGNC:1479"
                     /db_xref="MIM:114230"
                     /translation="MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGT
                     LFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGAL
                     GDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPT
                     KDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELK
                     KPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNG
                     SLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRH
                     YSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLE
                     EEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEEEKTESGKR"
     polyA_site      2046
                     /gene="CAPN2"
                     /gene_synonym="CANP2; CANPL2; CANPml; mCANP"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agtggccgca gcagcgcgcc gggccctggc cgcgccccag ccgagcgcag cgcggagtcg
       61 ccccgacctt tctctgcgca gtacggccgc cgggaccgca gcatggcggg catcgcggcc
      121 aagctggcga aggaccggga ggcggccgag gggctgggct cccacgacag ggccatcaag
      181 tacctcaacc aggactacga ggcgctgcgg aacgagtgcc tggaggccgg gacgctcttc
      241 caggacccgt ccttcccggc catcccctcg gccctgggct tcaaggagtt ggggccctac
      301 tccagcaaaa cccggggcat cgagtggaag cgccccacgg agatctgcgc tgacccccag
      361 tttatcattg gaggagccac ccgcacagac atctgccaag gagccctggg tgactgctgg
      421 ctgctggcag ccattgcctc cctcaccttg aatgaagaaa tcctggctcg agtcgtcccc
      481 ctaaaccaga gcttccagga aaactatgca gggatctttc acttccagtt ctggcaatac
      541 ggcgagtggg tggaggtggt ggtggatgac aggctgccca ccaaggacgg ggagctgctc
      601 tttgtgcatt cagccgaagg gagcgagttc tggagcgccc tgctggagaa ggcatacgcc
      661 aagatcaacg gatgctatga agcgctatca gggggtgcca ccactgaggg cttcgaagac
      721 ttcaccggag gcattgctga gtggtatgag ttgaagaagc cccctcccaa cctgttcaag
      781 atcatccaga aagctctgca aaaaggctct ctccttggct gctccatcga catcaccagc
      841 gccgcggact cggaggccat cacgtttcag aagctggtga aggggcacgc gtactcggtc
      901 accggagccg aggaggttga aagtaacgga agcctacaga aactgatccg catccgaaat
      961 ccctggggag aagtggagtg gacagggcgg tggaatgaca actgcccaag ctggaacact
     1021 atagacccag aggagaggga aaggctgacc agacggcatg aagatggaga attctggatg
     1081 tctttcagtg acttcctgag gcactattcc cgcctggaga tctgtaacct gaccccagac
     1141 actctcacca gcgataccta caagaagtgg aaactcacca aaatggatgg gaactggagg
     1201 cggggctcca ccgcgggagg ttgcaggaac tacccgaaca cattctggat gaaccctcag
     1261 tacctgatca agctggagga ggaggatgag gacgaggagg atggggagag cggctgcacc
     1321 ttcctggtgg ggctcattca gaagcaccga cggcggcaga ggaagatggg cgaggacatg
     1381 cacaccatcg gctttggcat ctatgaggtt ccagaggagg agaagactga gtcagggaaa
     1441 aggtgaaccc tgcagactgt actagaagac aacgcgggag cacagaggag accaggaccc
     1501 aattcccagg ctgtgtgacc ttggacacgt tacagctcct ctctgcattt cagggttttg
     1561 tttttttttt ttttgatttt tggtttgttt gtttgttttt tgtctcgctc tttcacccag
     1621 gatgaagtgc agtggcatga tctcgactca ctgcaacctc tacctcctgg gttcaagtga
     1681 ttctcctgct tcagcctccc cagtagctgg gactacaggc acgcaccagg atgccaggcc
     1741 aatttttgta tttttagtag agacggggtt tcaccatggt ggccaggctg gtcttgaact
     1801 cctgacctca ggtgatccac ccccttcagc ctcccaaagt gctaggatta caggtgtagc
     1861 caccgtgcct ggctgcattt cagtttattt ttcagtaaaa ctggtcaacc atccacctca
     1921 ctgcactacc gtggaatgac ttaaattttg cgagagcatt tgggcccaca gtcaccgctt
     1981 gctgaagcag atgggatgcc tggtccaagg tcacgattat taaagtagac acacggggca
     2041 ctttga
//
