LOCUS       XM_011537764            4879 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens calcium/calmodulin dependent protein kinase
            kinase 2 (CAMKK2), transcript variant X14, mRNA.
ACCESSION   XM_011537764
VERSION     XM_011537764.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011537764.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 38% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4879
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..4879
                     /gene="CAMKK2"
                     /gene_synonym="CAMKK; CAMKKB"
                     /note="calcium/calmodulin dependent protein kinase kinase
                     2; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 46 ESTs, 2125 long SRA reads, 1
                     Protein, and 90% coverage of the annotated genomic feature
                     by RNAseq alignments, including 25 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:10645"
                     /db_xref="HGNC:HGNC:1470"
                     /db_xref="MIM:615002"
     CDS             598..1872
                     /gene="CAMKK2"
                     /gene_synonym="CAMKK; CAMKKB"
                     /codon_start=1
                     /product="calcium/calmodulin-dependent protein kinase
                     kinase 2 isoform X10"
                     /protein_id="XP_011536066.1"
                     /db_xref="GeneID:10645"
                     /db_xref="HGNC:HGNC:1470"
                     /db_xref="MIM:615002"
                     /translation="MSWASPFIQGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFP
                     RRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMV
                     FELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDG
                     HIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYC
                     FVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEI
                     KLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGN
                     PFEGSRREERSLSAPGNLLTKKPTRECESLSELKEARQRRQPPGHRPAPRGGGGSALV
                     RGSPCVESCWAPAPGSPARMHPLRPEEAMEPE"
ORIGIN      
        1 gtggctccgc tgccggatgg gagtgcccca gtgtgctgga tgaagctggc gcatgcacca
       61 tgtcatcatg tgtctctagc cagcccagca gcaaccgggc cgccccccag gatgagctgg
      121 ggggcagggg cagcagcagc agcgaaagcc agaagccctg tgaggccctg cggggcctct
      181 catccttgag catccacctg ggcatggagt ccttcattgt ggtcaccgag tgtgagccgg
      241 gctgtgctgt ggacctcggc ttggcgcggg accggcccct ggaggccgat ggccaagagg
      301 tcccccttga cacctccggg tcccaggccc ggccccacct ctccggtcgc aagctgtctc
      361 tgcaagagcg gtcccagggt gggctggcag ccggtggcag cctggacatg aacggacgct
      421 gcatctgccc gtccctgccc tactcacccg tcagctcccc gcagtcctcg cctcggctgc
      481 cccggcggcc gacagtggag tctcaccacg tctccatcac gggtatgcag gactgtgtgc
      541 agctgaatca gtataccctg aaggatgaaa ttggaaagat cttaacttct ggatagtatg
      601 tcatgggcat ctccctttat ccagggctcc tatggtgtcg tcaagttggc ctacaatgaa
      661 aatgacaata cctactatgc aatgaaggtg ctgtccaaaa agaagctgat ccggcaggcc
      721 ggctttccac gtcgccctcc accccgaggc acccggccag ctcctggagg ctgcatccag
      781 cccaggggcc ccattgagca ggtgtaccag gaaattgcca tcctcaagaa gctggaccac
      841 cccaatgtgg tgaagctggt ggaggtcctg gatgacccca atgaggacca tctgtacatg
      901 gtgttcgaac tggtcaacca agggcccgtg atggaagtgc ccaccctcaa accactctct
      961 gaagaccagg cccgtttcta cttccaggat ctgatcaaag gcatcgagta cttacactac
     1021 cagaagatca tccaccgtga catcaaacct tccaacctcc tggtcggaga agatgggcac
     1081 atcaagatcg ctgactttgg tgtgagcaat gaattcaagg gcagtgacgc gctcctctcc
     1141 aacaccgtgg gcacgcccgc cttcatggca cccgagtcgc tctctgagac ccgcaagatc
     1201 ttctctggga aggccttgga tgtttgggcc atgggtgtga cactatactg ctttgtcttt
     1261 ggccagtgcc cattcatgga cgagcggatc atgtgtttac acagtaagat caagagtcag
     1321 gccctggaat ttccagacca gcccgacata gctgaggact tgaaggacct gatcacccgt
     1381 atgctggaca agaaccccga gtcgaggatc gtggtgccgg aaatcaagct gcacccctgg
     1441 gtcacgaggc atggggcgga gccgttgccg tcggaggatg agaactgcac gctggtcgaa
     1501 gtgactgaag aggaggtcga gaactcagtc aaacacattc ccagcttggc aaccgtgatc
     1561 ctggtgaaga ccatgatacg taaacgctcc tttgggaacc cattcgaggg cagccggcgg
     1621 gaggaacgct cactgtcagc gcctggaaac ttgctcacca aaaaaccaac cagggaatgt
     1681 gagtccctgt ctgagctcaa ggaagcaagg cagcgaagac aacctccagg gcaccgaccc
     1741 gccccccgtg ggggaggagg aagtgctctt gtgagaggca gtccctgcgt ggaaagttgc
     1801 tgggcccccg cccccggctc ccccgcacgc atgcatccac tgcggccgga ggaggccatg
     1861 gagcccgagt agctgcctgg atcgctcgac ctcgcatgcg cgccgcgtcg cctctggggg
     1921 gctgctgcac cgcgtttcca tagcagcatg tcctacggaa acccagcacg tgtgtagagc
     1981 ctcgatcgtc atctctggtt atttgttttt tcctttgttg ttttaaaggg gacaaaaaaa
     2041 aaaaaaggac ttgactccat gacgtcgacc gtggccgctg gctggctgga caggcgggtg
     2101 tgaggagttg cagacccaaa cccacgtgca ttttgggaca attgcttttt aaaacgtttt
     2161 tatgccaaaa atccttcatt gtgattttca gaaccacgtc agatatacca agtgactgtg
     2221 tgtggggttt gacaactgtg gaaaggcgag cagaaaactc cggcggtctg aggccatgga
     2281 ggtggttgct gcatttgaga gggagtaggg ggctagatgt ggctcctagt gcaaaccgga
     2341 aaccatggca ccttccagag ccgtggtctc aaggagtcag agcagggctg gccctcagta
     2401 gctgcaggga gctttgatgc aacttatttg taagaaggat ttttaaattt tttatgggta
     2461 gaattgtagt caggaaaaca gaaagggctt gaaatttaat aagtgctgct ggaaggggat
     2521 tttccaagcc tggaagggta ttcagcagct gtggtgggga aacatttctc ctgaaagact
     2581 gaacgtgttt cttcatgaca gctgctcaaa gcaggtttct gagatagctg accgagctct
     2641 ggtaaatctc tttgtcaaat tacgaaaact tcagggtgaa atcctatgct tccatgtaca
     2701 ttacatggct taagattaaa caaaaacatt tttcaagtct ctaactagag tgaactctag
     2761 agcacagtag ttcagaaact atttagagct tccaggatat atttcacagc ttcaggcatg
     2821 tgatcagtta gagccgatga aacctatgcc cgcctgtata tatattagca gcttagctag
     2881 ttcataacct gtatattcta aagactgcta aggttttgtt ttcattttaa atcctagctg
     2941 attgttgtgg tcaatgaaat acccagtttc tggagggcca ggtgggaaat gctttcactg
     3001 gaccaacaca caaatgatca tcctgaggat ctgagcttcc ctagactcca cacaataacc
     3061 ttggggcacc cttttagaga agactgttga aacccacagc actcgttggg gtatgaggaa
     3121 accagggctt ggcacaggaa gttccccttt gtagctaaaa gtccagaaag aaagggttca
     3181 tctttttgac ttccaactga tattgggaag tttggttgag gttcaagtgt gactccttcc
     3241 agagccacag gtaggggagt gtgaagttga gggggaggaa agctggaagg actctgcctt
     3301 gggagattcc cagctctgct ttccagcgct tggtggaatc tgggctgggg aaagacggca
     3361 ccgggaaact ctgcttcccc attgtttcca tctgatcagc tgtggtgtga ggacttctca
     3421 gacaaaggca aggcctcgtg cccctgccca gcccattcat ggagccctgg gccttcttgg
     3481 cttccataga tcctaagctc ttgactgtag tttagccaga cttgttttgc tatcttataa
     3541 gcagttcaga attagggaat gctggttttg aagagcaaag gacaggtagt ctagagaggg
     3601 tcgtctggcc tgcttgctgg gtctttgtaa cccagcactt cctcttgccc tcctggcttt
     3661 atgtttatgg ggagaggact caatagctcc accccttctg gcaccagatg gggcttggtt
     3721 agtttgcaat aagcaccttg cagaggttaa agccagcggg tccctagtct taggcccagc
     3781 ctgcttgtgt gggctctggc ctggcctggt ggctggccca gggggcagca gtgcttagag
     3841 cttctgcagg gcttctcttg tttacacagc tgcatcagac aatgccattt ctccccacca
     3901 cggaaccttc catctaagat ttcttccagg gaatgccagc aatcaggcag cacccagctg
     3961 tgggggcagt ggggtggggg agacccacat tgatgacttt ttttttttct tttaatgaag
     4021 aaacaccaaa gaaagctgtg gaaaggacct gccccacatg aaaaggataa gccaagatgg
     4081 ctgtaaacac agagcatttg agctgccact cttggagcac attgattttt caaaagccag
     4141 ctctgtcagg aaaggaggtg ctgttatgag cagctcttcc agtgggcaaa gaggacgccc
     4201 ataatttctt ccattgctag ctcatctgtg ggaccaattt ggtgtaagca acctgtggcc
     4261 tgcacttgtg gcctcgaagg aagcacaaac cctccatcca cttcccattt cctctgccct
     4321 tttccacctc ccccttccat cccaccagct gccagtggct cccagaaagc cttattgagc
     4381 cccttgttga cacttggggc tgcggaggcc tctccctact ggtctggcct ttcctgagag
     4441 gcaggtcttc cgtcctcaga gcctttctgg aacaaggaga atgcctgtgc aggtggacac
     4501 acaggcctgg cctgtcgctc tcacttgtct tccagcgggg agcttcacgt tgccgagtgg
     4561 aagaaccatg acctccactt gcttccaagg tgctagggaa gtttcagggt acgctggttc
     4621 ccctctccag ctggaggccg agtttctggg gactgcagat ttttctactc tgtgatcgat
     4681 tcaatgcccg atgcttctgt ttcattcccg accctttcta ctatgcattt tccttttatc
     4741 aggtgtataa agttaaatac tgtgtattta tcactaaaaa gtacatgaac ttaagagaca
     4801 actaagcctt tcgtgttttt ccacaggtgt ttaagcttct ctgtacagtt gaaataaaca
     4861 gacagcaaaa tggtgccaa
//
