LOCUS       XM_011515550            4602 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens calcium/calmodulin dependent protein kinase
            II beta (CAMK2B), transcript variant X3, mRNA.
ACCESSION   XM_011515550
VERSION     XM_011515550.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011515550.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4602
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..4602
                     /gene="CAMK2B"
                     /gene_synonym="CAM2; CAMK2; CAMKB; CaMKIIbeta; MRD54"
                     /note="calcium/calmodulin dependent protein kinase II
                     beta; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 78 ESTs, 702 long SRA
                     reads, 16 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 8 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:816"
                     /db_xref="HGNC:HGNC:1461"
                     /db_xref="MIM:607707"
     CDS             174..2231
                     /gene="CAMK2B"
                     /gene_synonym="CAM2; CAMK2; CAMKB; CaMKIIbeta; MRD54"
                     /codon_start=1
                     /product="calcium/calmodulin-dependent protein kinase type
                     II subunit beta isoform X3"
                     /protein_id="XP_011513852.1"
                     /db_xref="GeneID:816"
                     /db_xref="HGNC:HGNC:1461"
                     /db_xref="MIM:607707"
                     /translation="MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKI
                     INTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDI
                     VAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGL
                     AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDED
                     QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRS
                     TVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSAAKSLLNKKADGVKPQTNS
                     TKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDIL
                     SSVRRGSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGP
                     PPCLSPALLGPLSSPSPRISDILNSVRRGSGTPEAEGPSPVGPPPCPSPTIPGPLPTP
                     WMDDIPGLLPPPPVGRHQTGGGVEILLEKRLLGHGLGMAGQWLARKQEIIKTTEQLIE
                     AVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNP
                     HVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVA
                     PLQ"
ORIGIN      
        1 agatctcgcg tgcgctcgcc gcccggcgca gcccagcccg gcccccgcct ggcgccgcga
       61 gccgaggtgt ctcccgcgcc cgcgcccgtg tcgccgccgt gcccgcgagc gggagccgga
      121 gtcgccgccg cccgagcgca gccgagcgca cgccgagccc gtccgccgcc gccatggcca
      181 ccacggtgac ctgcacccgc ttcaccgacg agtaccagct ctacgaggat attggcaagg
      241 gggctttctc tgtggtccga cgctgtgtca agctctgcac cggccatgag tatgcagcca
      301 agatcatcaa caccaagaag ctgtcagcca gagatcacca gaagctggag agagaggctc
      361 ggatctgccg ccttctgaag cattccaaca tcgtgcgtct ccacgacagc atctccgagg
      421 agggcttcca ctacctggtc ttcgatctgg tcactggtgg ggagctcttt gaagacattg
      481 tggcgagaga gtactacagc gaggctgatg ccagtcactg tatccagcag atcctggagg
      541 ccgttctcca ttgtcaccaa atgggggtcg tccacagaga cctcaagccg gagaacctgc
      601 ttctggccag caagtgcaaa ggggctgcag tgaagctggc agacttcggc ctagctatcg
      661 aggtgcaggg ggaccagcag gcatggtttg gtttcgctgg cacaccaggc tacctgtccc
      721 ctgaggtcct tcgcaaagag gcgtatggca agcctgtgga catctgggca tgtggggtga
      781 tcctgtacat cctgctcgtg ggctacccac ccttctggga cgaggaccag cacaagctgt
      841 accagcagat caaggctggt gcctatgact tcccgtcccc tgagtgggac accgtcactc
      901 ctgaagccaa aaacctcatc aaccagatgc tgaccatcaa ccctgccaag cgcatcacag
      961 cccatgaggc cctgaagcac ccgtgggtct gccaacgctc cacggtagca tccatgatgc
     1021 acagacagga gactgtggag tgtctgaaaa agttcaatgc caggagaaag ctcaagggag
     1081 ccatcctcac caccatgctg gccacacgga atttctcagc agccaagagt ttactcaaca
     1141 agaaagcaga tggagtcaag ccccagacga atagcaccaa aaacagtgca gccgccacca
     1201 gccccaaagg gacgcttcct cctgccgccc tggagcctca aaccaccgtc atccataacc
     1261 cagtggacgg gattaaggag tcttctgaca gtgccaatac caccatagag gatgaagacg
     1321 ctaaagcccc cagggtcccc gacatcctga gctcagtgag gaggggctcg ggagccccag
     1381 aagccgaggg gcccctgccc tgcccatctc cggctccctt tagccccctg ccagccccat
     1441 cccccaggat ctctgacatc ctgaactctg tgagaagggg ttcaggaacc ccagaagccg
     1501 agggccccct ctcagcgggg cccccgccct gcctgtctcc ggctctccta ggccccctgt
     1561 cctccccgtc ccccaggatc tctgacatcc tgaactctgt gaggaggggc tcagggaccc
     1621 cagaagccga gggcccctcg ccagtggggc ccccgccctg cccatctccg actatccctg
     1681 gccccctgcc caccccatgg atggatgaca tcccagggct gctgccaccc ccacctgtgg
     1741 ggagacacca gactgggggt ggtgtggaga tactcttaga gaagaggctg ctgggccacg
     1801 ggctcggcat ggcagggcag tggctagccc ggaagcagga gatcattaag accacggagc
     1861 agctcatcga ggccgtcaac aacggtgact ttgaggccta cgcgaaaatc tgtgacccag
     1921 ggctgacctc gtttgagcct gaagcactgg gcaacctggt tgaagggatg gacttccaca
     1981 gattctactt cgagaacctg ctggccaaga acagcaagcc gatccacacg accatcctga
     2041 acccacacgt gcacgtcatt ggagaggatg ccgcctgcat cgcttacatc cggctcacgc
     2101 agtacattga cgggcagggc cggccccgca ccagccagtc tgaggagacc cgcgtgtggc
     2161 accgccgcga cggcaagtgg cagaacgtgc acttccactg ctcgggcgcg cctgtggccc
     2221 cgctgcagtg aagagctgcg ccctggtttc gccggacaga gttggtgttt ggagcccgac
     2281 tgccctcggg cacacggcct gcctgtcgca tgtttgtgtc tgcctcgttc cctcccctgg
     2341 tgcctgtgtc tgcagaaaaa caagaccaga tgtgatttgt taaaaaaaaa caaaaaaaaa
     2401 aaaaaaaaaa acaagatgac gacgacaacc acaaaaaaaa ttgacatcag atgaaatgaa
     2461 aaaaaaaaaa aacaaaaaaa actaaaggaa ggaaaaagct gtaaaaatca ctggcattcg
     2521 tggggccact ccccacccaa gctccacgtg tgtccgtctg tgctcctggc ctctggggga
     2581 ccagctggga catgaacttg tctgccaggc ccccgtcgcg tgctgaacgg tgttagtttg
     2641 taggtaacgc acacacccca cacctaaggt gtctgcatcc tcctgccaac gcatgggctc
     2701 cacgtggtgt gctcgctggc tgtcgtgact gtcagctgtc tcttgggagg ggctgtgggg
     2761 gcccgctggg ctgcctcctt tcccgctagt tgtgcctgag agttgctgtt gttcctgctt
     2821 tcccttccct tcctttcatc ccctgaaggg ctaggtgtgg gttttccgtg cccggtatcc
     2881 ccacacaccc agcacggaca acccttcggc agagcccagg ccggcccctc accccctgga
     2941 gtattgaaac tggagtcccg tccccaaggc cttcagagat gcccctacac acccagggct
     3001 ccagctctgg tccttctggg ggagtaaagt gcaaagaggg gcacagctta gttttgggcc
     3061 tctcgccgag caagagacag cactgctggc tacagctcca acacagccag ctgtggcaag
     3121 aggactctgc ctgggctggc ccccctcctg tgtgaggtgt ctgtcccttc tctgctggcc
     3181 agcagcagat gcactggcag ctcccaaccc tgtttccgcc cctcggccct cccccagcct
     3241 gttcggcttc tctgcagccc gcaaggggga gcagactttt gacaaaggac tgcgggcctc
     3301 gctcaagtcc ctgagccccc agctgaagct gggaggggag gccaggcttt gtgtctgggc
     3361 atattcgtct gctgatgggg tttggggaag cctggggctt ggggtttggt cgggtggtgc
     3421 agctagtggc agagcgggat cagaggtggt ggctgcccag cttctgggct gagacaaggg
     3481 tctgtgcagg ggtttactga agtgggagtg cctttggaat ctgggccggg agcagaaggg
     3541 agcaaaagct acagtgggag ccagcctagg gcacatggga ggcgtgaggg cagtgctgcc
     3601 cgtgcagtgt caggtgtgcc agtgccttgg cgggctgcag tgcgtgtgag ggcaccttct
     3661 aggtgggcca gggatgcagc tatggagata aggcgggctg gggacagaaa caggtgggca
     3721 cagggcccag gacaccagcg gatggagggc agggtctagc cctgtgctcc tgagcgtcgg
     3781 ctgcctgggt tcgaggcggt gggtccccgg ccccttgtga tggtgtgtac catgggggag
     3841 ctcggggaca gggcaagccc gagcatggtg gggctgcagg gtgggtctga agccaggttg
     3901 ggtgggggtg gtcacaagcc ctgactgcag agggtcaggg gctcctgccc cagtgcctgc
     3961 ccactttcaa ttcacattgt tttcaacaag gattttcttt atcttcccct acaaatcaag
     4021 ccaagggagg ggcacagaat ggggaacagg acacaggatc ctaaactcca aggggactgt
     4081 ccaccgatga acactcagag tggacaccat cttccgtcca cgctgtgccc aggacagctg
     4141 tccccatcca tgaacacagg gtaaacatct gccgggctcc gcaccagtgg ctccctgggc
     4201 catgggacag cggcagggct caccacggac agcacgtggc ccagcagccg gccaccctgg
     4261 cgtcctgggg cctcctcccc tcctctccct ctcaccttgt cacctccacg gagctgcctg
     4321 tctgggataa tttggggatt ttttttctgg gggataattc ttttgcatga cccctaaaga
     4381 gcaagccaca ccggtctgct agctaggtgt ccgcggtgtg gtggtggcgg ccgctggcca
     4441 gcgctgcaag gggtcggctg cccacggtgc tggctggcct cccctcctct ctctttttgc
     4501 tgagtttcat tgtcttttct ttctgagcct tgtaagtgta caaaaattat tcttattttg
     4561 ttctgtctcg ggaaactgca aataaaagaa aaacaggaca aa
//
