LOCUS       NM_153711               9787 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens calcium homeostasis modulator family member 5
            (CALHM5), mRNA.
ACCESSION   NM_153711
VERSION     NM_153711.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9787)
  AUTHORS   Bhat,E.A., Sajjad,N., Banawas,S. and Khan,J.
  TITLE     Human CALHM5: Insight in large pore lipid gating ATP channel and
            associated neurological pathologies
  JOURNAL   Mol Cell Biochem 476 (10), 3711-3718 (2021)
   PUBMED   34089472
  REMARK    GeneRIF: Human CALHM5: Insight in large pore lipid gating ATP
            channel and associated neurological pathologies.
            Review article
REFERENCE   2  (bases 1 to 9787)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 9787)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 9787)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY035391.1, BC032556.2, AL121953.21 and AA468683.1.
            
            On Nov 22, 2018 this sequence version replaced NM_153711.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.29163.1,
                                           SRR1660803.17019.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000368599.4/ ENSP00000357588.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 HY035391.1         108-113
            7-1145              BC032556.2         1-1139
            1146-9776           AL121953.21        12223-20853
            9777-9787           AA468683.1         16-26               c
FEATURES             Location/Qualifiers
     source          1..9787
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.1"
     gene            1..9787
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="calcium homeostasis modulator family member 5"
                     /db_xref="GeneID:254228"
                     /db_xref="HGNC:HGNC:21568"
     exon            1..598
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..988
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="protein FAM26E; family with sequence similarity 26
                     member E"
                     /codon_start=1
                     /product="calcium homeostasis modulator protein 5"
                     /protein_id="NP_714922.1"
                     /db_xref="CCDS:CCDS5108.1"
                     /db_xref="GeneID:254228"
                     /db_xref="HGNC:HGNC:21568"
                     /translation="MDAFQGILKFFLNQKTVIGYSFMALLTVGSERLFSVVAFKCPCS
                     TENMTYGLVFLFAPAWVLLILGFFLNNRSWRLFTGCCVNPRKIFPRGHSCRFFYVLGQ
                     ITLSSLVAPVMWLSVALLNGTFYECAMSGTRSSGLLELICKGKPKECWEELHKVSCGK
                     TSMLPTVNEELKLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTY
                     AQKEKEQLENTFLDYANKLSERNLKCFFENKRPDPFPMPTFAAWEAASELHSFHQSQQ
                     HYSTLHRVVDNGLQLSPEDDETTMVLVGTAHNM"
     exon            599..9787
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3396..3401
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="hexamer: AATAAA"
     polyA_site      3424
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="major polyA site"
     regulatory      3525..3530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="hexamer: AATAAA"
     polyA_site      3550
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
     regulatory      4814..4819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="hexamer: AATAAA"
     polyA_site      4834
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="major polyA site"
     regulatory      9319..9324
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="hexamer: AATAAA"
     polyA_site      9340
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
     regulatory      9763..9768
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
                     /note="hexamer: AATAAA"
     polyA_site      9787
                     /gene="CALHM5"
                     /gene_synonym="C6orf188; dJ493F7.3; FAM26E"
ORIGIN      
        1 gccacagctg ctctgccaat aacaaaggca cagcattttc cctctgtgca tctccaacat
       61 ggatgctttt cagggcattt taaaattctt ccttaatcag aaaactgtta ttggctacag
      121 cttcatggct ctgctgaccg tgggaagtga gcgtctcttt tctgttgtgg cttttaagtg
      181 cccctgcagc actgagaata tgacctatgg gctggttttc ctctttgctc ctgcctgggt
      241 gttactgatc ctgggattct ttctgaacaa taggtcgtgg agactcttca caggctgctg
      301 tgtgaatccc aggaaaatct ttcccagagg ccacagctgc cgtttcttct acgtcctcgg
      361 ccagatcact ctgagctcat tggtggctcc agtgatgtgg ctttctgtgg ctctgctcaa
      421 tggaactttc tatgaatgtg ccatgagcgg gacgagaagt tcaggactcc tggaactgat
      481 ttgcaagggt aagcccaaag agtgctggga agaacttcac aaagtatctt gtggcaaaac
      541 tagcatgcta cctaccgtca atgaagaact gaaactctcc cttcaggccc agtctcagat
      601 tctaggatgg tgcctgattt gttcagcgtc tttcttctct ctgctcacca catgttatgc
      661 tcgctgccga tctaaagtta gctaccttca gctgagtttt tggaagacat atgcacaaaa
      721 ggagaaggag cagttggaaa atacatttct ggactatgcc aacaagctga gcgagaggaa
      781 cctgaaatgt ttttttgaaa acaagaggcc agatcctttt cccatgccta cgtttgctgc
      841 ctgggaggct gcttcagagc tgcattcttt ccaccaaagc cagcaacact atagcaccct
      901 ccacagagtg gtggacaatg gtctgcaact tagccctgag gatgatgaga cgacaatggt
      961 ccttgtgggt actgcccaca atatgtagct catccaccat caatgactca tggtgttgag
     1021 tggcatgctc attctgtgat cctcctaacg tatcaccagc aacctgtgtg tctctgtatt
     1081 ttcttacatt tggagtatgt ttacaagaca ataacacaaa ggaaactgct ttgaagctct
     1141 caagtggaac atcaggatgt gctcaaattg atgctgaggg gtgacaaagg tgctcttgca
     1201 ttggtggaga ggggctcagt aggcctaaat gttgctccaa gatctaagat tttatcattc
     1261 aacagacaga ctcatgtgag agggctcatc agtctctgta aatattggtt gcagaattta
     1321 ggggcagaag caatggcttg tgagtgagca agttactctt aacataggtt gccctacaca
     1381 gtggctcctg cagtgtgatc agcaggagtc tctgtcctac aaatctacac ttttaaggat
     1441 gtatgaaatt gtggaattca ttccctcagg atctgaagat ctcagttctc aaaaatcaca
     1501 agttgcaaga atatgatacc taaaattgaa agtttttcac atgttttcac tgtatactga
     1561 aaatactccc ctggaagcag ggctgcatca taatttttgt gggctttatg tacttttgcc
     1621 tttgcgaacc atttcctaca ttcaaaatag tagtaacaaa tatatatata tatatatata
     1681 tatatatata tatatatata tatatataca cacacacaga aatatatatt tataactgca
     1741 ttgataaaag gtgaatatat tagcattttc ttcaacctaa aagtttatgt attttcttct
     1801 gattttaaaa gaaattaaaa acattttagt gggcccttac aagtattatg gtccttaggc
     1861 acagtgctta ctaggccgtg ggtatgtctt agtgcgtttg ggctactata acaaaatatc
     1921 atagataggt ggcttataca aaatagaaat ttatttctca cagttctgga ggctgggaag
     1981 tccgaggtca ggctgccagc atgctcaggt tctggtgaga gcaattttcc aggttgcaaa
     2041 ctgcttgctg acttctcagt gtccttccat ggtggaaagt gcaaataagc tcccttgagc
     2101 atttttataa ggcactaatc ccattcctgg aggctccacc ttcatgaccc aattacttct
     2161 caaggctctg cttcttagta ctatcagctt gggggttaag atttcaacat atgaaattgg
     2221 gggagacaca aacattcaga ctatagtagg gtaaattgac cttggctaaa ggtctgggga
     2281 cactgtccaa agcagtactg gcataaaact gcattgcagt cttacattta tcagaaataa
     2341 tgcaaatctt gcattctaca atgtactata tccatgttag tatgtacata tatatgtgta
     2401 tgtatatatg tacataaatt ctccttaaat ctctgagaag aattgtgctt taaaaaagaa
     2461 ctatgttttg tgctgtggct cataccttac agtggtagtc tatgtctctt agtttgagaa
     2521 agctgaatat taacttctta ttaacatgaa acatgatggc aaactgaatc ctacaagtat
     2581 aggacccaga acatatctat gttattgtca tttacaagaa gaaatatgta tttggtcttt
     2641 cttcctattc ctggtgcaga gctcctaaaa cctttgggac ctcccaagtg atgtgtctgg
     2701 tagtacgcga atgagatgac tgatagttag gggcttctga atggcctcag aatagggtct
     2761 ggttgccacg ggaaccaacc atgtgtttag agggttggaa ctttcagccc cactcccaga
     2821 ccttggggaa ggaagagggg ctgaaggttg agtcgatcac aaatggataa tgatttaatc
     2881 aatcatgcct aagaataaag cttcccataa aaatctaaag gacaaggttc agagagcttc
     2941 tgcattgctc aatacatgag gagtggtgag cccaaagggg ccgtggaagc tccgtgcccc
     3001 ttcccccaaa cctgttcctg tgcctccatc tggctgtttc tgagttatat tattttataa
     3061 tagactgatg atagtaaata aagccctttc ctgagttctg tgagctactc tagcaaatgg
     3121 tgaaatctga gaaggaaatc atgggaacct ctgctttgta gccacgtcag atagaagatg
     3181 tgagtaactt tggaacctac tgcttgtgac tggtgtctga agttggggga gatcttatgg
     3241 gactgagctc ttaacctgct ggggatctgc acttaatgcc gattaatgcc agaattgaat
     3301 tgtatgatat ccagttggta ttggagaatt ggccagtgtg ggagaaaacc cacacagttg
     3361 gtggcaagga gtgttcagtg ttgagtgtga atgtcaataa aaaaaggttt gttttttcta
     3421 cgtacaatat ctttgggaac ttggaggtgc agggtcagac gtctgtgtgt gtatgtggca
     3481 gggacagaac agggattagg gatgtgaggg ggtagagttt tcagaataaa gggagagaaa
     3541 attcagcaaa gagttctcct tcttaatctt tcttgactta aagtttgtct gcccttaagt
     3601 gtcttctgag ctggaaaaag acatatagga actggccgat gccgatgcct cttttgcagt
     3661 gtgtgagagg ctgaaacaga agttctacag aagtaggtta gctgtaagga gctgaggatt
     3721 gaggagtcat atctggggga tattcctgcc accctcaagt ccagggactt tctgcactca
     3781 aaaaacttac gctcatgaca atgactgcct cattcaagaa aacccaagct gactggcaag
     3841 aagccagcag cctgggtact tgttgctgca gcttagtaag tagcagaaga gctcatcctc
     3901 ctcctctgga agaagccact taacaggttc tcatcctgac tcctaaattc cttaacagtc
     3961 ctttactcag gaataaaaca agtccaagaa aacttatctg tcccacaaat agtcctggag
     4021 gcagtggagt aagataggga gagcaaattg gtgtctgctc ttgagtatct tgagggaatg
     4081 ggtatctaga ggcagcagga tgaactggct ttgatagcag agactttaaa atgtgtggac
     4141 cattagttgt ctttggatgt gctccctaga ggctgcgcct gacacaggga gctgtgtata
     4201 catgatttat taaaaggaaa tcctcttagg agaaacatat tagcaggata aacacaagaa
     4261 agaatgcagt tacaagtgga gtctcaatca atcccagagg aaattctggg acttcagcct
     4321 cagcttgacc tatggggggg ctctggaatg tcagatttct cctgatccca agtgtgctct
     4381 ggggcttcca ttgcagccaa gagagagcat tccccagaaa actccaggtg aggagtctcc
     4441 agtggcccaa gggtgatcct ccagaggagg ttacactgcc gaactgggac attggcaccc
     4501 tggatttgaa tatctagaga gggcacccaa tggtcatact aatgtttgcc ataacagtct
     4561 cttctaggtc tagacttgaa gcatatggaa gggtccttgg gctagagcca acccaagccc
     4621 aggctgactc ccttttaata cttctaattt tccctgaaga tctggtcttc tccctaccac
     4681 cactacccta ttacataaga gaaaaggatt ggagaatgct cttgaaaaga atgtgatgct
     4741 ttcccataca aggaatatac tcaaggaaaa atttcatggc acaaaatgct gattctgtcc
     4801 aatttatccc atgaataaat tgtgtacaca tatatatatg attcttttgt ttttcctgtg
     4861 cagttccttc cttttttcag gctcaaccac ttaattcagc tttaggatac attcagctta
     4921 ttcatatcaa atataaagtg ggagaaaaaa aggtatgtaa caaagattac aaaaataagg
     4981 catggcagac aaatcactac ataattctat gcattatacc ttaaagtaat gtattgtaaa
     5041 atatatgtgt ccaaagcaac ttttaaaatt tttgtatggt tttctacttg agacctttaa
     5101 agcatcacta aaaatgtata catttaatga gaaaacgatg acattattga ttcaaattag
     5161 ttgtttcaaa gcctgatgat ccactgattt actctaaaaa ctggttaaag caatccagaa
     5221 gtcactgggt agcagaaaac tgctaccgct tctcacatga tatatttcaa gtacttcaac
     5281 tattaactat attattctat ttagactttg gtggttccga attctctaag gtaattatct
     5341 taattttcta atatttccct ctcatttttc tctcttattt taaatatccc ctgttgtaca
     5401 agccagagga tattaatttc ctttgtgggt agtgcttgga cttctctgat tttagatccc
     5461 aaaatcatta agaaaaagct aagaggttgg catgagaggt tggatggaaa gcatctatct
     5521 gtgtttgtca gtagctctcg atgttggctg caaattggaa tcacctgggg gcctttgaca
     5581 atcacaatgt ctggacccat ttcctgagaa cctgatgtaa cttttctggg ttagggcctg
     5641 aacattgaga tttcttttaa aagctttcta agtgattata atgtgcagtc atggtgaaga
     5701 actactgatt ttatatgggg agtcagtgaa ggtggtgagg ggctgtgagg ttgaaatatt
     5761 ggaaatgtta tctggatttc aaacagtaga gtatgataaa aatttaaaaa ctggctctcc
     5821 aggaaaaaag agacatccta atatgatgta tttgccaata taccatgggt tttcttgggc
     5881 tgggatgaac tttcagaagt tttacagtga gcattttttt ttttatgaat ttaaattggt
     5941 tctagctaag caattttgga gtatctttga tgtacctggg tctctcattt taataaacat
     6001 aacagtggta tgttagtcag ggttctccag agaaacagaa ccaacagtac aacagtatat
     6061 atacatacat acatatatat gtgtgtgcat gtgtgtgtgt gtatgcgtgt atatatatat
     6121 atgctacata tatgaaaggg gatttcttgt gggaatatat attatatata acaaaacatg
     6181 acaaatatat aacaaaatat atgtgctata tatattgtgt gtgtatatat atatgaaaga
     6241 ggatttattg tggaaattgg ctcatgtgat tatgaaggct gagaaggccc atgacgtgcc
     6301 acctgtaagc tggagaatca gggaaatgtg tagggtggct caagtcccag tctgagggcc
     6361 tgagaaccag gggagttgat ggtacaaatc ccagagccaa aggcaaagga acctgaagtt
     6421 tttatttcca agggccaata gataaggaga atattggtga cccaactcca ggagacagag
     6481 aaaagattgg tgacccaact cgagtggaga gagagggaga gagagagaga cagagagcaa
     6541 atttgcccat cctctccctt tttgtcctac ccaggccctc aatggattgt atggtgcctg
     6601 cccaggttag gtgagggcag attttcctta ctcagtccac tgattcaaat gccaatcttt
     6661 tttggaaaca cccctacata catacccaga aataatgctt taataactat ctggctaccc
     6721 cttaatccaa tcaagttgac atctaaaatt aaccagcaca tgtgataaat taaatatggt
     6781 tcaatggctc cttctggcag atgtagtcgt gttatcctca ctttgaatct gaccttatga
     6841 accaataaaa tatggcagac atgaggtaga ttgttaagca gtatcacagt ttatgccttg
     6901 gtctcttaca atgttgcaat gctcaacagt ctggtaaaag ccactatgta agaactgcaa
     6961 ttactcaggg actaccaagc tctgaagagg cccaagctag ccagtgggag gagagagaga
     7021 gagataaaaa gagagagaga gagagatccc aatggctcca attgtctcag atattctagc
     7081 ttaggggtca ggcatgtgaa tgaaggagcc attttaaaca ttcaggcccc agtgtacacg
     7141 acatggagaa gaaccaggaa gtccaaccaa cagtgagaat aaaaggcccc agatctatgg
     7201 ccctaatcaa atcattgcag ccatctccaa acatttgacc cactccagtg gaggctgcag
     7261 gctttgtaga gaagtccttg ccatgtccta tccaactcca tgaccccaaa aatcatgagc
     7321 ttaaataaat gtttgtggct ttaagccact gaattttggg gcaatatgaa gcgacagaac
     7381 ctgaacacta acatgaaaat cagaatttat aaaaagacaa aaattacagg caaattgtat
     7441 ttatacattt atacattctc cctatgcata gagagcattt tcttcaatca tgttttcttt
     7501 ttctttaggt tccagttagc agtatagcat ctacagcatg atttgataga tgctgataag
     7561 taggtctcta aaatctctcc accaaagctg gagattcact ttcaattatt tttggttaat
     7621 ttttgtttga aaggaataca aacatattat tgggaggagt aacacattaa actattattt
     7681 gtcattaata tctacgaaaa aatagcaagt gagggtttca gactaggctg gccttcagta
     7741 agctggaaag agattgttct tctagtcgtc tctcaaaatg ttatcttcag actgtcaaca
     7801 tcagtatcac gatgaagctt gttagaaatg cagaatcaga cagtatctaa aacctgttga
     7861 gtcaagcctg cagtttaacg tgatcctagc tgattccagt tcaagctaaa tttgataaca
     7921 ctaaggcagt ggttctcaaa ctttagtcca tataaaaatc atctggaggg cttattaaaa
     7981 tgtggattgc tgaactccac ccccagggtg tctgattcag taggtctggg gtgaggcaag
     8041 ataatctgca tttctaacag gttctcaggt gatactgatg ctgctggtct agggactaca
     8101 tcttgaaaat aactgctcta cagcacagag caggctattc tggggaaggc aggctgtaag
     8161 aaactcagaa tcctggcctg cactccagat ctactgaatc ggtcatcagc ccgtccaaga
     8221 ttttggggtg cctttccatt cattcaagga tacctttcta ttcattcaag gatatatttt
     8281 gtcctttagg aatattttaa agtttacttc acataagttt tacatgtttc ttgtaaactc
     8341 tatttgtagg tgttttcttt gttcctgttg taaatggttt cttttttcca ctatatcttt
     8401 ctaagtgatt gttgtctgag tacgtgaaaa gctattgtct tatgcttatt aattttatct
     8461 ctctactaat tcttttattg tttgtagggc ttttcagaat ttgaaagtaa acattttgca
     8521 acctttgatg acaaaatgga tctagacaat aaataatgaa ttctaaacta ttaggtgaaa
     8581 gcagaatggg gtcagaccta tgcaatttga agccactcat ctatattagc atcactaaaa
     8641 atcaaagcag atgctacgtg ccttatgatg caaggcaaga ataagtacat agtatcacat
     8701 gtgaaatatt gtttcctaag aagctaaacc taatcaagta tttagacatt actgctagtt
     8761 tataggaaac ataagcaaca aaaaacaagg caattagcac cacaaaaaaa caaccaggta
     8821 catctagatc taacagaaca ttccatttta cagatgactc agtctcccca cagattaaca
     8881 gtattaagaa aggagaataa aggagatata agtgacttaa taaccagata tgctatatag
     8941 accttatttg tatcctgttt ccaacaacca actgtaacaa gatatctttg agatatttag
     9001 gaaaatatga atgaatatta gatgattttt agagaattat taattttgct atgtgtggta
     9061 atggtgtgcc gatttatgtt ttttaaaaag ttcttcagtt agagatgtat atttaaatat
     9121 ttatgtgtga actgccatga tgtctagaag tttctttaaa atactctaga aaaaagagtt
     9181 tagggagaaa gctgaaagat gaaataagat tggcaaaata tggaaactat tgaagctgga
     9241 tggtaggtac acggaattca ttacattatt ctctttacat ttgtatatgt ttgaaaaatt
     9301 tcataaggta cacaacaaaa taaatgacat ggtcacctca gttattttgc tgaagttttg
     9361 tcaatcaccc cctgcttagc tggagtttac cttctagtat cattctcagc aaaggctcac
     9421 aggaatgcta ttctctgaat tcttacatat tcagcctgtt ggcctgttct cgaattgaag
     9481 gacagcttgt ctggttcata ctttctctac atgagtgtat tgtaagcatt acttcattgt
     9541 cttttgtcat tgaatattgc tgaggtggcc acagcctgat ttctgatgcc atctctattt
     9601 ctttctttat tactaacaag atgttttatc ctatattctc attggtttct ttatctttca
     9661 tgtccaaaaa tgttaaatag gccttcaggt aggtcttttt ggaacgattt ttcctgctac
     9721 aagtttactc tttcattgtg gagaatcatt ttcttatatt tcaataaaaa agttggaaaa
     9781 ttttcaa
//
