LOCUS       NM_005795               6112 bp    mRNA    linear   PRI 06-DEC-2024
DEFINITION  Homo sapiens calcitonin receptor like receptor (CALCRL), transcript
            variant 1, mRNA.
ACCESSION   NM_005795
VERSION     NM_005795.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6112)
  AUTHORS   Selvarajan,I., Kiema,M., Huang,R.T., Li,J., Zhu,J., Polonen,P.,
            Ord,T., Ounap,K., Godiwala,M., Golebiewski,A.K., Ravindran,A.,
            Maklin,K., Toropainen,A., Stolze,L.K., Arce,M., Magnusson,P.U.,
            White,S., Romanoski,C.E., Heinaniemi,M., Laakkonen,J.P., Fang,Y.
            and Kaikkonen,M.U.
  TITLE     Coronary Artery Disease Risk Variant Dampens the Expression of
            CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer
            in Endothelial Cells In Vitro
  JOURNAL   Arterioscler Thromb Vasc Biol 44 (6), 1330-1345 (2024)
   PUBMED   38602103
  REMARK    GeneRIF: Coronary Artery Disease Risk Variant Dampens the
            Expression of CALCRL by Reducing HSF Binding to Shear Stress
            Responsive Enhancer in Endothelial Cells In Vitro.
REFERENCE   2  (bases 1 to 6112)
  AUTHORS   Tang,S., Li,S., Shi,X., Sheng,L., Mu,Q., Wang,Y., Zhu,H., Xu,K.,
            Zhou,M., Xu,Z., Wu,A. and Ouyang,G.
  TITLE     CALCRL induces resistance to daunorubicin in acute myeloid leukemia
            cells through upregulation of XRCC5/TYK2/JAK1 pathway
  JOURNAL   Anticancer Drugs 35 (2), 163-176 (2024)
   PUBMED   37948318
  REMARK    GeneRIF: CALCRL induces resistance to daunorubicin in acute myeloid
            leukemia cells through upregulation of XRCC5/TYK2/JAK1 pathway.
REFERENCE   3  (bases 1 to 6112)
  AUTHORS   Tang,S., Zhu,H., Sheng,L., Mu,Q., Wang,Y., Xu,K., Zhou,M., Xu,Z.,
            Wu,A. and Ouyang,G.
  TITLE     CALCRL knockdown suppresses cancer stemness and chemoresistance in
            acute myeloid leukemia with FLT3-ITD and DNM3TA-R882 double
            mutations
  JOURNAL   Drug Dev Res 85 (1), e22137 (2024)
   PUBMED   38349260
  REMARK    GeneRIF: CALCRL knockdown suppresses cancer stemness and
            chemoresistance in acute myeloid leukemia with FLT3-ITD and
            DNM3TA-R882 double mutations.
REFERENCE   4  (bases 1 to 6112)
  AUTHORS   Huang,Z., Zhang,H., Xing,C., Zhang,L., Zhu,H., Deng,Z., Yin,L.,
            Dong,E., Wang,C. and Peng,H.
  TITLE     Identification and validation of CALCRL-associated prognostic genes
            in acute myeloid leukemia
  JOURNAL   Gene 809, 146009 (2022)
   PUBMED   34655717
  REMARK    GeneRIF: Identification and validation of CALCRL-associated
            prognostic genes in acute myeloid leukemia.
REFERENCE   5  (bases 1 to 6112)
  AUTHORS   Josephs,T.M., Belousoff,M.J., Liang,Y.L., Piper,S.J., Cao,J.,
            Garama,D.J., Leach,K., Gregory,K.J., Christopoulos,A., Hay,D.L.,
            Danev,R., Wootten,D. and Sexton,P.M.
  TITLE     Structure and dynamics of the CGRP receptor in apo and
            peptide-bound forms
  JOURNAL   Science 372 (6538) (2021)
   PUBMED   33602864
  REMARK    GeneRIF: Structure and dynamics of the CGRP receptor in apo and
            peptide-bound forms.
REFERENCE   6  (bases 1 to 6112)
  AUTHORS   McLatchie,L.M., Fraser,N.J., Main,M.J., Wise,A., Brown,J.,
            Thompson,N., Solari,R., Lee,M.G. and Foord,S.M.
  TITLE     RAMPs regulate the transport and ligand specificity of the
            calcitonin-receptor-like receptor
  JOURNAL   Nature 393 (6683), 333-339 (1998)
   PUBMED   9620797
REFERENCE   7  (bases 1 to 6112)
  AUTHORS   Aiyar,N., Rand,K., Elshourbagy,N.A., Zeng,Z., Adamou,J.E.,
            Bergsma,D.J. and Li,Y.
  TITLE     A cDNA encoding the calcitonin gene-related peptide type 1 receptor
  JOURNAL   J Biol Chem 271 (19), 11325-11329 (1996)
   PUBMED   8626685
REFERENCE   8  (bases 1 to 6112)
  AUTHORS   Fluhmann,B., Muff,R., Hunziker,W., Fischer,J.A. and Born,W.
  TITLE     A human orphan calcitonin receptor-like structure
  JOURNAL   Biochem Biophys Res Commun 206 (1), 341-347 (1995)
   PUBMED   7818539
REFERENCE   9  (bases 1 to 6112)
  AUTHORS   Foord,S.M. and Craig,R.K.
  TITLE     Isolation and characterisation of a human
            calcitonin-gene-related-peptide receptor
  JOURNAL   Eur J Biochem 170 (1-2), 373-379 (1987)
   PUBMED   2826160
REFERENCE   10 (bases 1 to 6112)
  AUTHORS   Skofitsch,G. and Jacobowitz,D.M.
  TITLE     Autoradiographic distribution of 125I calcitonin gene-related
            peptide binding sites in the rat central nervous system
  JOURNAL   Peptides 6 (5), 975-986 (1985)
   PUBMED   3001670
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA217003.1, AC007319.2, U17473.1 and AC074020.4.
            
            On Nov 23, 2018 this sequence version replaced NM_005795.5.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments. An in-frame
            AUG is located 11 codons upstream of the annotated translation
            start site but is not being annotated as a start site since it is
            not conserved and is in a weak Kozak sequence context.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK291630.1, SRR1660803.65897.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000392370.8/
                                                ENSP00000376177.3
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                DA217003.1         43-76
            35-45               AC007319.2         100687-100697       c
            46-286              U17473.1           9-249
            287-296             AC007319.2         40154-40163         c
            297-2223            U17473.1           261-2187
            2224-6112           AC074020.4         139955-143843       c
FEATURES             Location/Qualifiers
     source          1..6112
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q32.1"
     gene            1..6112
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="calcitonin receptor like receptor"
                     /db_xref="GeneID:10203"
                     /db_xref="HGNC:HGNC:16709"
                     /db_xref="MIM:114190"
     exon            1..214
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            215..305
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            306..470
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            471..557
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     CDS             507..1892
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="calcitonin gene-related peptide type 1 receptor;
                     CGRP type 1 receptor; calcitonin receptor-like"
                     /codon_start=1
                     /product="calcitonin gene-related peptide type 1 receptor
                     precursor"
                     /protein_id="NP_005786.1"
                     /db_xref="CCDS:CCDS2293.1"
                     /db_xref="GeneID:10203"
                     /db_xref="HGNC:HGNC:16709"
                     /db_xref="MIM:114190"
                     /translation="MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTA
                     QYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVT
                     KICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISL
                     GIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFI
                     HLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSL
                     YYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKA
                     VRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQ
                     AILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIE
                     NVLLKPENLYN"
     exon            558..690
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            691..801
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            802..914
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1006
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1133
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1287
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1348
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1415
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1634
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1676
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..6112
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4761..4766
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="hexamer: ATTAAA"
     polyA_site      4784
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="major polyA site"
     regulatory      4938..4943
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="hexamer: AATAAA"
     polyA_site      4957
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="major polyA site"
     regulatory      6099..6104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
                     /note="hexamer: AATATA"
     polyA_site      6112
                     /gene="CALCRL"
                     /gene_synonym="CGRPR; CRLR; LMPHM8"
ORIGIN      
        1 agaacaacct ctctctctcc agcagagagt gtcacctcct gctttaggac catcaagctc
       61 tgctaactga atctcatcct aattgcagga tcacattgca aagctttcac tctttcccac
      121 cttgcttgtg ggtaaatctc ttctgcggaa tctcagaaag taaagttcca tcctgagaat
      181 atttcacaaa gaatttcctt aagagctgga ctgggtcttg acccctgaat ttaagaaatt
      241 cttaaagaca atgtcaaata tgatccaaga gaaaatgtga tttgagactg gagacaattg
      301 tgcatatcgt ctaataataa aaacccatac tagcctatag aaaacaatat ttgaaagatt
      361 gctaccacta aaaagaaaac tactacaact tgacaagact gctgcaaact tcaatttgtc
      421 aaccacaact tgacaaggtt gctataaaac aagattgcta caacttctag tttatgttat
      481 acagcatatt tcattttggc ttaatgatgg agaaaaagtg taccctgtat tttctggttc
      541 tcttgccttt ttttatgatt cttgttacag cagaattaga agagagtcct gaggactcaa
      601 ttcagttggg agttactaga aataaaatca tgacagctca atatgaatgt taccaaaaga
      661 ttatgcaaga ccccattcaa caagcagaag gcgtttactg caacagaacc tgggatggat
      721 ggctctgctg gaacgatgtt gcagcaggaa ctgaatcaat gcagctctgc cctgattact
      781 ttcaggactt tgatccatca gaaaaagtta caaagatctg tgaccaagat ggaaactggt
      841 ttagacatcc agcaagcaac agaacatgga caaattatac ccagtgtaat gttaacaccc
      901 acgagaaagt gaagactgca ctaaatttgt tttacctgac cataattgga cacggattgt
      961 ctattgcatc actgcttatc tcgcttggca tattctttta tttcaagagc ctaagttgcc
     1021 aaaggattac cttacacaaa aatctgttct tctcatttgt ttgtaactct gttgtaacaa
     1081 tcattcacct cactgcagtg gccaacaacc aggccttagt agccacaaat cctgttagtt
     1141 gcaaagtgtc ccagttcatt catctttacc tgatgggctg taattacttt tggatgctct
     1201 gtgaaggcat ttacctacac acactcattg tggtggccgt gtttgcagag aagcaacatt
     1261 taatgtggta ttattttctt ggctggggat ttccactgat tcctgcttgt atacatgcca
     1321 ttgctagaag cttatattac aatgacaatt gctggatcag ttctgatacc catctcctct
     1381 acattatcca tggcccaatt tgtgctgctt tactggtgaa tctttttttc ttgttaaata
     1441 ttgtacgcgt tctcatcacc aagttaaaag ttacacacca agcggaatcc aatctgtaca
     1501 tgaaagctgt gagagctact cttatcttgg tgccattgct tggcattgaa tttgtgctga
     1561 ttccatggcg acctgaagga aagattgcag aggaggtata tgactacatc atgcacatcc
     1621 ttatgcactt ccagggtctt ttggtctcta ccattttctg cttctttaat ggagaggttc
     1681 aagcaattct gagaagaaac tggaatcaat acaaaatcca atttggaaac agcttttcca
     1741 actcagaagc tcttcgtagt gcgtcttaca cagtgtcaac aatcagtgat ggtccaggtt
     1801 atagtcatga ctgtcctagt gaacacttaa atggaaaaag catccatgat attgaaaatg
     1861 ttctcttaaa accagaaaat ttatataatt gaaaatagaa ggatggttgt ctcactgttt
     1921 tgtgcttctc ctaactcaag gacttggacc catgactctg tagccagaag acttcaatat
     1981 taaatgactt tttgaatgtc ataaagaaga gccttcacat gaaattagta gtgtgttgat
     2041 aagagtgtaa catccagctc tatgtgggaa aaaagaaatc ctggtttgta atgtttgtca
     2101 gtaaatactc ccactatgcc tgatgtgacg ctactaacct gacatcacca agtgtggaat
     2161 tggagaaaag cacaatcaac ttttctgagc tggtgtaagc cagttccagc acaccattgc
     2221 atgaattcac aaacaaatgg ctgtaaaact aaacatacat gttgggcatg attctaccct
     2281 tattgcccca agagacctag ctaaggtcta taaacatgaa gggaaaatta gcttttagtt
     2341 ttaaaactct ttatcccatc ttgattgggg cagttgactt tttttttgcc cagagtgccg
     2401 tagtcctttt tgtaactacc ctctcaaatg gacaatacca gaagtgaatt atccctgctg
     2461 gctttctttt ctctatgaaa agcaactgag tacaattgtt atgatctact catttgctga
     2521 cacatcagtt atatcttgtg gcatatccat tgtggaaact ggatgaacag gatgtataat
     2581 atgcaatcct acttctatat cattaggaaa acatcttagt tgatgctaca aaacaccttg
     2641 tcaacctctt cctgtcttac caaacagtgg gagggaattc ctagctgtaa atataaattt
     2701 tgtcccttcc atttctactg tataaacaaa ttagcaatca ttttatataa agaaaatcaa
     2761 tgaaggattt cttattttct tggaattttg taaaaagaaa ttgtgaaaaa tgagcttgta
     2821 aatactccat tattttattt tatagtctca aatcaaatac atacaaccta tgtaattttt
     2881 aaagcaaata tataatgcaa caatgtgtgt atgttaatat ctgatactgt atctgggctg
     2941 attttttaaa taaaatagag tctggaatgc tatatttggt aaatatttta aagacaacca
     3001 gatgccagca tcagaagtct gtttgagaac taagagaaca gaaacatcta tcataagata
     3061 tatttatttt aaaaacacaa ggtcactatt ttattgaata tatttgtttt gataactcat
     3121 accttaataa taggtgtgtt tgacatattt cttttttcat tttgacaatg aactcacatt
     3181 ctaatccaga aattttaaac aactactgtg ataaatacca atctgctact tttatagatt
     3241 ttaccccatt aaaatattac tttactgact tttactatgt gaagatatat agctttggaa
     3301 atgtcccagg ctattcaaga aatataaaaa actagaagga tactatatat accatataca
     3361 atgctttaat attttaatag agctactgta tataatacaa attagggaaa tacttgaata
     3421 tatcattgag aaaaaattat tgtcagatct tactgaatta ttgtcagact ttattaaata
     3481 aagatagaag aaaaccttgc taatgaatta aagtgaaatt tgcatgggat tcagtttctc
     3541 taatgttatt ttccgctgaa atctctaaag aacaagaatg acttcaatta gtaaaagtca
     3601 attttgggaa aagtcatggg tatctgtttt ttaagtgtgt caatctgatt aaaatggatg
     3661 aaacaaatta ctcatcataa gttgtttctt aagctgtcaa tatgtcaata gatggtgagt
     3721 tcagaactta tttcaaattg ctaagacaaa ttatctaaat tcgtaagaat taacatatag
     3781 aatggtctgg tcagtacatt tataatttat ctatgcatga aaaagtattg ttttgtttga
     3841 aacatgaatt tcatagcaag ctgccataga aaggaacgca ggctgttcta gaccttcaac
     3901 tgcctaaatt atacaaaaat tcattttaat aaactcaatt attagctatt tattattcaa
     3961 agacccatat ttaaatcctt tgctgaccat gttgacatat atcagccttc ttctagacaa
     4021 actgtcaact ctcaaccatc ttgacagtag aagtgacagt aaaaaatgtt gaatgatcag
     4081 agattatatt aaaataaaca tgtaattttc aagtattttt gttgtgcttt tataatatta
     4141 attctagatc agatttattt tatagccagg gtttgtctgt tgtagagtct tgaggcgtag
     4201 cagtcattca tgattaatca ctgttagttt tgtacccata tatttttaga atagttttaa
     4261 atgttagatt tctcaaaagc taaatgctac ttaatatctt tgtatcatac tcataaagca
     4321 aagtaaatct gacacttttt ttaaagcaaa cttctttgct gtcaaaaaaa taaatttggg
     4381 gaaatttcta gcttttaaaa tgtagatctg cattttactg tgattacttg tgaaagtcat
     4441 attttaattt tctaaattct aatttgtcat tttatttcct aaagttaatt tccaatgcat
     4501 ttattcataa aatattcatt ctggaatgca gtgtttgttt aaatgtaatc caatgtatat
     4561 agaattagtg gtggctgtag tgctgtattt attgcttata atttttttta aatgtgaact
     4621 tacttttaat tttctcttgg ttttaatctg ctagtagaaa ccactagtta tctgtaaaaa
     4681 tatattcaag atattctgat caattataac aatttatgtt atgcctagag tatatctcta
     4741 ttttttgatt gtatgaaaat attaaagtta tgagttaaag tttattttca ctgatattta
     4801 ctacagtgcc aaataatcta atttataaac ataattctta cagtaatcaa tgggatactt
     4861 ctcaaaatta acaaatctct taacaaaata tatcttttgc cctctttaaa gtcttcagta
     4921 aaccagtaaa tgaattcaat aaaccaatta agaaaaagtc atgatttgtt tttcaaacta
     4981 aaaaaatcca actatactac aatggatgca aactccttct tatgctgaaa gaagaaaaag
     5041 gatgtctcaa aataagaaaa tgttcagaaa ttcatctcct ttatctacta tatttcattt
     5101 tgtagttttg tttaaatatt agaaagaaaa ataagtattt aaaggtaatt tttaaagagg
     5161 gcatattcat ggctctcaca caaatataaa atgaaaatgt ttcaaagatt tcgtttaact
     5221 cattaattaa tgaaggaaca agtaagatgt tacaaaaatt caaaggagaa ttcaaaatat
     5281 cacactatat gagaatatta aaaatgttga aataaattta taaataagtg caaaaccact
     5341 ctatccttag ggcaataatc agttgcattc cacttaataa ctaattttta tttttatgat
     5401 caataataat gtacatcatt ttctgttttc tggagaaaat gcccatttaa aacacttgtg
     5461 tttttttctt ataatctctc ctccttgtga ttatactaat ctcaaagaaa gaatattctt
     5521 gattaaaaat attgctagtt taataaggtt tggcctattg ttgagatagg tacatgagag
     5581 tgttaattac aatatagacc tcctcaagtt ggttttacaa atctagaacc atagtgcact
     5641 ttttaacagc ttcattgaga tatacttgac atatcatata atacttcata ttcaaagcag
     5701 tttttagtat attagtagag tatattttaa tacatccata gagacacgct accatcacca
     5761 atttcattac atttttatga ccttgagaag aaacagtgta tcctttagcc atcacttctc
     5821 tatccctcta tctctacttt catttcagct ataaacatca ctaatttaca ttctgtctca
     5881 acagatttcc ctattctaga ctttcatatg attgtaatca tatagtatgt gaccttttgt
     5941 gactaaatga tttcacttat gtttttaaaa ttcattcatg ttttggcatg tatcaatgtt
     6001 tccttttatt ccattgggtg aacataccac attttattta ttcatttgtc tgttgatgga
     6061 tatgtttgtt ttgcttttac cttttggtta ttataaataa tatacctata aa
//
