LOCUS       XM_047420822            4124 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens calcium voltage-gated channel auxiliary
            subunit alpha2delta 1 (CACNA2D1), transcript variant X11, mRNA.
ACCESSION   XM_047420822
VERSION     XM_047420822.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4124
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..4124
                     /gene="CACNA2D1"
                     /gene_synonym="CACNA2; CACNL2A; CCHL2A; DEE110; LINC01112;
                     lncRNA-N3"
                     /note="calcium voltage-gated channel auxiliary subunit
                     alpha2delta 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 15 ESTs, 222 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 38 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:781"
                     /db_xref="HGNC:HGNC:1399"
                     /db_xref="MIM:114204"
     CDS             498..3737
                     /gene="CACNA2D1"
                     /gene_synonym="CACNA2; CACNL2A; CCHL2A; DEE110; LINC01112;
                     lncRNA-N3"
                     /codon_start=1
                     /product="voltage-dependent calcium channel subunit
                     alpha-2/delta-1 isoform X11"
                     /protein_id="XP_047276778.1"
                     /db_xref="GeneID:781"
                     /db_xref="HGNC:HGNC:1399"
                     /db_xref="MIM:114204"
                     /translation="MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDL
                     VTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLAL
                     EAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQIS
                     YQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYY
                     PASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSV
                     SEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYK
                     KGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFNKYNKDKKVRVFTFSVGQH
                     NYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVY
                     LDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCP
                     NGYYFAIDPNGYVLLHPNLQPKEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRT
                     LVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARYSETL
                     KPDNFEESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVL
                     LDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFY
                     KRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWI
                     ENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDP
                     SLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAA
                     WSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDC
                     GNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRK
                     GPDVCFDNNVLDQLKCTTSRACTMMSAPIFILLQVFMWCGWSVTFSNFS"
     polyA_site      4124
                     /gene="CACNA2D1"
                     /gene_synonym="CACNA2; CACNL2A; CCHL2A; DEE110; LINC01112;
                     lncRNA-N3"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gacttgccta agaagccaga cggagcctct cgcttccaca agtctctctg cctgccattc
       61 cccgattcct gcagccaccc ccaccctcca gcgccgtcac ccctcctccg cccccgcccc
      121 cgcctccgcc ttcgcctcgg caatcggggg aataaatcag ggaggaaacc gagagggaga
      181 gcgagagcgc gcgagcgccg gcgggctcgc cgaggtctgt ttccaaagtc gcccttgatg
      241 gcggcggagg caaggcggcc gcggcgcgga gcagccgacg cacgctagtg ggtccgcccg
      301 ccaccgcccc ttcctcggcg tccgctcccg cccttgccgt cccccgcgcg gctccgcgcc
      361 tcgggccccg ggcgcagcca gccctccaga cgcccgcggt cccggcggcg tgtgctgctc
      421 ttcctccgcc cgcggtttcc agcgccgctc cttcccccgc ttgggcaggg agggggcatt
      481 gatcttcgat cgcgaagatg gctgctggct gcctgctggc cttgactctg acacttttcc
      541 aatctttgct catcggcccc tcgtcggagg agccgttccc ttcggccgtc actatcaaat
      601 catgggtgga taagatgcaa gaagaccttg tcacactggc aaaaacagca agtggagtca
      661 atcagcttgt tgatatttat gagaaatatc aagatttgta tactgtggaa ccaaataatg
      721 cacgccagct ggtagaaatt gcagccaggg atattgagaa acttctgagc aacagatcta
      781 aagccctggt gcgcctggca ttggaagcgg agaaagttca agcagctcac cagtggagag
      841 aagattttgc aagcaatgaa gttgtctact acaatgcaaa ggatgatctc gatcctgaga
      901 aaaatgacag tgagccaggc agccagagga taaaacctgt tttcattgaa gatgctaatt
      961 ttggacgaca aatatcttat cagcacgcag cagtccatat tcctactgac atctatgagg
     1021 gctcaacaat tgtgttaaat gaactcaact ggacaagtgc cttagatgaa gttttcaaaa
     1081 agaatcgcga ggaagaccct tcattattgt ggcaggtttt tggcagtgcc actggcctag
     1141 ctcgatatta tccagcttca ccatgggttg ataatagtag aactccaaat aagattgacc
     1201 tttatgatgt acgcagaaga ccatggtaca tccaaggagc tgcatctcct aaagacatgc
     1261 ttattctggt ggatgtgagt ggaagtgtta gtggattgac acttaaactg atccgaacat
     1321 ctgtctccga aatgttagaa accctctcag atgatgattt cgtgaatgta gcttcattta
     1381 acagcaatgc tcaggatgta agctgttttc agcaccttgt ccaagcaaat gtaagaaata
     1441 aaaaagtgtt gaaagacgcg gtgaataata tcacagccaa aggaattaca gattataaga
     1501 agggctttag ttttgctttt gaacagctgc ttaattataa tgtttccaga gcaaactgca
     1561 ataagattat tatgctattc acggatggag gagaagagag agcccaggag atatttaaca
     1621 aatacaataa agataaaaaa gtacgtgtat tcacgttttc agttggtcaa cacaattatg
     1681 acagaggacc tattcagtgg atggcctgtg aaaacaaagg ttattattat gaaattcctt
     1741 ccattggtgc aataagaatc aatactcagg aatatttgga tgttttggga agaccaatgg
     1801 ttttagcagg agacaaagct aagcaagtcc aatggacaaa tgtgtacctg gatgcattgg
     1861 aactgggact tgtcattact ggaactcttc cggtcttcaa cataaccggc caatttgaaa
     1921 ataagacaaa cttaaagaac cagctgattc ttggtgtgat gggagtagat gtgtctttgg
     1981 aagatattaa aagactgaca ccacgtttta cactgtgccc caatgggtat tactttgcaa
     2041 tcgatcctaa tggttatgtt ttattacatc caaatcttca gccaaaggag ccagtaacat
     2101 tggatttcct tgatgcagag ttagagaatg atattaaagt ggagattcga aataagatga
     2161 ttgatgggga aagtggagaa aaaacattca gaactctggt taaatctcaa gatgagagat
     2221 atattgacaa aggaaacagg acatacacat ggacacctgt caatggcaca gattacagtt
     2281 tggccttggt attaccaacc tacagttttt actatataaa agccaaacta gaagagacaa
     2341 taactcaggc cagatattcg gaaaccctga agccagataa ttttgaagaa tctggctata
     2401 cattcatagc accaagagat tactgcaatg acctgaaaat atcggataat aacactgaat
     2461 ttcttttaaa tttcaacgag tttattgata gaaaaactcc aaacaaccca tcatgtaacg
     2521 cggatttgat taatagagtc ttgcttgatg caggctttac aaatgaactt gtccaaaatt
     2581 actggagtaa gcagaaaaat atcaagggag tgaaagcacg atttgttgtg actgatggtg
     2641 ggattaccag agtttatccc aaagaggctg gagaaaattg gcaagaaaac ccagagacat
     2701 atgaggacag cttctataaa aggagcctag ataatgataa ctatgttttc actgctccct
     2761 actttaacaa aagtggacct ggtgcctatg aatcgggcat tatggtaagc aaagctgtag
     2821 aaatatatat tcaagggaaa cttcttaaac ctgcagttgt tggaattaaa attgatgtaa
     2881 attcctggat agagaatttc accaaaacct caatcagaga tccgtgtgct ggtccagttt
     2941 gtgactgcaa aagaaacagt gacgtaatgg attgtgtgat tctggatgat ggtgggtttc
     3001 ttctgatggc aaatcatgat gattatacta atcagattgg aagatttttt ggagagattg
     3061 atcccagctt gatgagacac ctggttaata tatcagttta tgcttttaac aaatcttatg
     3121 attatcagtc agtatgtgag cccggtgctg caccaaaaca aggagcagga catcgctcag
     3181 catatgtgcc atcagtagca gacatattac aaattggctg gtgggccact gctgctgcct
     3241 ggtctattct acagcagttt ctcttgagtt tgacctttcc acgactcctt gaggcagttg
     3301 agatggagga tgatgacttc acggcctccc tgtccaagca gagctgcatt actgaacaaa
     3361 cccagtattt cttcgataac gacagtaaat cattcagtgg tgtattagac tgtggaaact
     3421 gttccagaat ctttcatgga gaaaagctta tgaacaccaa cttaatattc ataatggttg
     3481 agagcaaagg gacatgtcca tgtgacacac gactgctcat acaagcggag cagacttctg
     3541 acggtccaaa tccttgtgac atggttaagc aacccagata ccgaaaaggg cctgatgtct
     3601 gctttgataa caatgtcttg gatcaactta agtgcacaac gagtcgtgcc tgtaccatga
     3661 tgtcagctcc tatcttcatt ttactgcaag ttttcatgtg gtgtggatgg tcagtcactt
     3721 tctctaattt ttcttagttt ttgtttttgg cttgaaattc tagaaaatca cccatattcc
     3781 taaatctgcg atattaatgt tcctgaaacc aggttattaa aatctcagga ccaatgttgt
     3841 tgttttgtaa atagctgatt tcaaatggca tgtacatttc taatcctaaa tgaaacatat
     3901 tcaatattta tgtaaaaatc atttttcata aagtttttgt gtaaaaattg tcattacaga
     3961 gacagatata caggcttcat ggtattttat gagaactacc taatgacaat ttttagaggt
     4021 ggttatctca atttatttac aaaagatgct aacacaaatt taatgcactc tttcaattcc
     4081 tttcagattt ttctactttt taaaataaat ctgacttaaa taac
//
