LOCUS       XM_006716120            7324 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens calcium voltage-gated channel auxiliary
            subunit alpha2delta 1 (CACNA2D1), transcript variant X12, mRNA.
ACCESSION   XM_006716120
VERSION     XM_006716120.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006716120.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7324
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..7324
                     /gene="CACNA2D1"
                     /gene_synonym="CACNA2; CACNL2A; CCHL2A; DEE110; LINC01112;
                     lncRNA-N3"
                     /note="calcium voltage-gated channel auxiliary subunit
                     alpha2delta 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 21 ESTs, 775 long SRA
                     reads, and 100% coverage of the annotated genomic feature
                     by RNAseq alignments, including 1 sample with support for
                     all annotated introns"
                     /db_xref="GeneID:781"
                     /db_xref="HGNC:HGNC:1399"
                     /db_xref="MIM:114204"
     CDS             161..3376
                     /gene="CACNA2D1"
                     /gene_synonym="CACNA2; CACNL2A; CCHL2A; DEE110; LINC01112;
                     lncRNA-N3"
                     /codon_start=1
                     /product="voltage-dependent calcium channel subunit
                     alpha-2/delta-1 isoform X12"
                     /protein_id="XP_006716183.1"
                     /db_xref="GeneID:781"
                     /db_xref="HGNC:HGNC:1399"
                     /db_xref="MIM:114204"
                     /translation="MQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAA
                     RDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPG
                     SQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREE
                     DPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLIL
                     VDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNK
                     KVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIF
                     NKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLG
                     RPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMG
                     VDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGVGIPTINLRKRRPN
                     IQNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNR
                     TYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGKMKDSETLKPDNFEES
                     GYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNE
                     LVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDN
                     YVFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSI
                     RDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVN
                     ISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFL
                     LSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFH
                     GEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRKGPDVCFDN
                     NVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHRLL"
ORIGIN      
        1 agtcagactc gccttctctc ttgcagtctg cctcccttga caggtgtgag ggacttccta
       61 agtgtcgcaa gccagccacc tggcatcagc cacccctgat gtagcgtgca ccttcagacc
      121 actgagctca tgaaagagta tcaaatcatg ggtggataag atgcaagaag accttgtcac
      181 actggcaaaa acagcaagtg gagtcaatca gcttgttgat atttatgaga aatatcaaga
      241 tttgtatact gtggaaccaa ataatgcacg ccagctggta gaaattgcag ccagggatat
      301 tgagaaactt ctgagcaaca gatctaaagc cctggtgcgc ctggcattgg aagcggagaa
      361 agttcaagca gctcaccagt ggagagaaga ttttgcaagc aatgaagttg tctactacaa
      421 tgcaaaggat gatctcgatc ctgagaaaaa tgacagtgag ccaggcagcc agaggataaa
      481 acctgttttc attgaagatg ctaattttgg acgacaaata tcttatcagc acgcagcagt
      541 ccatattcct actgacatct atgagggctc aacaattgtg ttaaatgaac tcaactggac
      601 aagtgcctta gatgaagttt tcaaaaagaa tcgcgaggaa gacccttcat tattgtggca
      661 ggtttttggc agtgccactg gcctagctcg atattatcca gcttcaccat gggttgataa
      721 tagtagaact ccaaataaga ttgaccttta tgatgtacgc agaagaccat ggtacatcca
      781 aggagctgca tctcctaaag acatgcttat tctggtggat gtgagtggaa gtgttagtgg
      841 attgacactt aaactgatcc gaacatctgt ctccgaaatg ttagaaaccc tctcagatga
      901 tgatttcgtg aatgtagctt catttaacag caatgctcag gatgtaagct gttttcagca
      961 ccttgtccaa gcaaatgtaa gaaataaaaa agtgttgaaa gacgcggtga ataatatcac
     1021 agccaaagga attacagatt ataagaaggg ctttagtttt gcttttgaac agctgcttaa
     1081 ttataatgtt tccagagcaa actgcaataa gattattatg ctattcacgg atggaggaga
     1141 agagagagcc caggagatat ttaacaaata caataaagat aaaaaagtac gtgtattcac
     1201 gttttcagtt ggtcaacaca attatgacag aggacctatt cagtggatgg cctgtgaaaa
     1261 caaaggttat tattatgaaa ttccttccat tggtgcaata agaatcaata ctcaggaata
     1321 tttggatgtt ttgggaagac caatggtttt agcaggagac aaagctaagc aagtccaatg
     1381 gacaaatgtg tacctggatg cattggaact gggacttgtc attactggaa ctcttccggt
     1441 cttcaacata accggccaat ttgaaaataa gacaaactta aagaaccagc tgattcttgg
     1501 tgtgatggga gtagatgtgt ctttggaaga tattaaaaga ctgacaccac gttttacact
     1561 gtgccccaat gggtattact ttgcaatcga tcctaatggt tatgttttat tacatccaaa
     1621 tcttcagcca aagcctattg gtgtaggtat accaacaatt aatttaagaa aaaggagacc
     1681 caatatccag aaccccaaat ctcaggagcc agtaacattg gatttccttg atgcagagtt
     1741 agagaatgat attaaagtgg agattcgaaa taagatgatt gatggggaaa gtggagaaaa
     1801 aacattcaga actctggtta aatctcaaga tgagagatat attgacaaag gaaacaggac
     1861 atacacatgg acacctgtca atggcacaga ttacagtttg gccttggtat taccaaccta
     1921 cagtttttac tatataaaag ccaaactaga agagacaata actcaggcca gatcaaaaaa
     1981 gggcaaaatg aaggattcgg aaaccctgaa gccagataat tttgaagaat ctggctatac
     2041 attcatagca ccaagagatt actgcaatga cctgaaaata tcggataata acactgaatt
     2101 tcttttaaat ttcaacgagt ttattgatag aaaaactcca aacaacccat catgtaacgc
     2161 ggatttgatt aatagagtct tgcttgatgc aggctttaca aatgaacttg tccaaaatta
     2221 ctggagtaag cagaaaaata tcaagggagt gaaagcacga tttgttgtga ctgatggtgg
     2281 gattaccaga gtttatccca aagaggctgg agaaaattgg caagaaaacc cagagacata
     2341 tgaggacagc ttctataaaa ggagcctaga taatgataac tatgttttca ctgctcccta
     2401 ctttaacaaa agtggacctg gtgcctatga atcgggcatt atggtaagca aagctgtaga
     2461 aatatatatt caagggaaac ttcttaaacc tgcagttgtt ggaattaaaa ttgatgtaaa
     2521 ttcctggata gagaatttca ccaaaacctc aatcagagat ccgtgtgctg gtccagtttg
     2581 tgactgcaaa agaaacagtg acgtaatgga ttgtgtgatt ctggatgatg gtgggtttct
     2641 tctgatggca aatcatgatg attatactaa tcagattgga agattttttg gagagattga
     2701 tcccagcttg atgagacacc tggttaatat atcagtttat gcttttaaca aatcttatga
     2761 ttatcagtca gtatgtgagc ccggtgctgc accaaaacaa ggagcaggac atcgctcagc
     2821 atatgtgcca tcagtagcag acatattaca aattggctgg tgggccactg ctgctgcctg
     2881 gtctattcta cagcagtttc tcttgagttt gacctttcca cgactccttg aggcagttga
     2941 gatggaggat gatgacttca cggcctccct gtccaagcag agctgcatta ctgaacaaac
     3001 ccagtatttc ttcgataacg acagtaaatc attcagtggt gtattagact gtggaaactg
     3061 ttccagaatc tttcatggag aaaagcttat gaacaccaac ttaatattca taatggttga
     3121 gagcaaaggg acatgtccat gtgacacacg actgctcata caagcggagc agacttctga
     3181 cggtccaaat ccttgtgaca tggttaagca acccagatac cgaaaagggc ctgatgtctg
     3241 ctttgataac aatgtcttgg aggattatac tgactgtggt ggtgtttctg gattaaatcc
     3301 ctccctgtgg tatatcattg gaatccagtt tctactactt tggctggtat ctggcagcac
     3361 acaccgcctg ttatgacctt ctaaaaacca aatctgcata gttaaactcc agaccctgcc
     3421 aaaacatgag ccctgccctc aattacagta acgtagggtc agctataaaa tcagacaaac
     3481 attagctggg cctgttccat ggcataacac taaggcgcag actcctaagg cacccactgg
     3541 ctgcatgtca gggtgtcaga tccttaaacg tgtgtgaatg ctgcatcatc tatgtgtaac
     3601 atcaaagcaa aatcctatac gtgtcctcta ttggaaaatt tgggagtttg ttgttgcatt
     3661 gttggtgatt acatgtgaaa gggttcccca tacaattgtt aatgaaccat aagaaatgtc
     3721 ttgatattga cctggaattt tgacttgctg caattttact aagaaaatct ctaaggggaa
     3781 agaaattatt tttgccttca ctttttcttc tgtgaaaagt taattcctgc tttaagtagc
     3841 aattattgaa atatatagag aaagagagaa ttaacattgg tctaaattgt tgaaatataa
     3901 ataatggcta attttctatg aaaaatttgc catgaataaa atgccttatg aagaacggct
     3961 tctttgccaa aaataaaaca caattgatga ccaattcaat tttgatgggg taatgaattg
     4021 atggtttgaa aatagtaact aagaaattat taaactaaag gtgcttgagg gagaaattag
     4081 aatatgtgac atatttcctc ataaatgtaa gcaagccctt aataaatgct ttgatgtaat
     4141 gttccttttg ttcacagtac agttatgtag tgctagccag atatttaaaa atgctctaag
     4201 aaaagcttgt caggggggag ggggaaatgt ttttcttgtg ataaatgaac tttggtttac
     4261 caagggtatt ttgcatgatg ctgctgctat tttaactttt cagttgtttt ttctcttact
     4321 gtagagtgta gtcattgaaa agttaactga gtgatattgt tatgtaagaa tctgaacctt
     4381 gcagtgtaaa tgcacttaag tcatctttaa aatgttgtta aactactctg aatatactgt
     4441 gcaatgtaaa tgctgaatga ttggggttag ataaatggtg aaatgagaat taatgaattt
     4501 tatacagatt catgctttcg cctgataacc tatgtacaga tattttaagt acataaatca
     4561 gatttgacac atttattttt tgaaaagtac atatatgttc tcaatgaaga ttcatcctag
     4621 gtttcctctt tgttcgtttc aatagtagca catacaatcc aaaagttcct gctactgctg
     4681 cttttgccct tccattttaa atggtatgat cgtttggcca aaatttccat gcaagttgat
     4741 aagggtttta caataatctg aacaaatagg aaaccttgaa tctctatgta tgcacatgaa
     4801 tacttgattg tgaataataa aagttgtttt ttatacagcc tcattggtga aaatggttag
     4861 tgtagtaaat cagatatttc attatagact aatatggtag cagattattt atgcttttaa
     4921 aaattatttt ctggagcaaa cagtatttga agaaaaggta aaaactatga atgtgtaatt
     4981 ctaagaatag ttaataattt tactgaaggc tgaacgtatg tagatatttt ttatgataaa
     5041 atgcagtttt tctttttttg gaacatgcca attactggta tgtgtatatg ctggaaattt
     5101 tcttacatat cctttttaag tcaaagttat taacattatc cagcatgctt taatatgctc
     5161 cacatatcaa agatataacc aataatttaa cgtagcttaa aagataacat ttgttttgtt
     5221 tttagctttg catacatttg taattccctc ccaccaccaa tataccttag gtaccatttg
     5281 tgtacatttc aagatttttt ttttcaataa aaaggtgggg ggaaatggaa tcactttgcc
     5341 aactattgtt ctaagagttg acatcagtta ccatttctaa tgcattgttg tgattttgta
     5401 gtgtcattca taactggtat tgacatttta gaaaacacca aagtgattta aaatatatgt
     5461 ggggaaaaaa acttctcact ctagtaacaa tgttttaatc atgttgtttg ttaaatattt
     5521 aaaagttatt gttcaatttt tgctagacta tcttaaatca tgatagtgtt gggaaggggg
     5581 tatcaaaata taaaattgtt agtttgtgta tataaacaat gcacattaaa acaattgaat
     5641 tgcttccagc atacaacaaa ctaccttaaa attatgttca aaatctatta aatatatttt
     5701 catggctaat gtcgagtata tgttttcatc aattacattg ttattgtatt aatcgcggtt
     5761 aaacttggca tctcttggca ggatcctatt taatttctgt tgccatcaaa atatatttat
     5821 atgcatgagt tttgctataa acctttattt tctgctataa agttatatat tatgacaacc
     5881 ataaatgcaa ttacaaattg ggtaagaaca agctgaataa aagttgttcc catgactaat
     5941 attagtcttc atgcttttag catatttttt aagacagtaa cactcatccc atcaaattat
     6001 tacattacat ttagtatttt tctgagttac attgacaaga acttaaatta tagcctgtta
     6061 ttaatattga tttccaacga ctgaacagta caacagatca ataaaaaagt ttatacactg
     6121 ctttaactaa tttttgttat actcatgtgg cttagtgtag ttagtcacta aaacagagtt
     6181 caagtgagct tggcaatggt gttgagtaac aagaaagaat tttgcattaa tgatttcttt
     6241 ttattttcct catttaaaca accagcatta ctgccaaaca ccaaccgtgg tccatatttg
     6301 taacaggttt ttaacatgac atagttagca agtttgattg aagagatttt taggtcctgg
     6361 gcctataaga ttttagtatg atcttttttc atgtttctaa tgcttgaggt gttactgctt
     6421 aacttgggaa aaaaaaaaac aaaaaacagt gttcctgcca tttgtaagtt ttcctataat
     6481 attcctttta ttaactttaa aactggactt atcgggttca aataggcagt atccctttta
     6541 agtgaccttt gcaacccaag tgttacttgc ttatttgatg ctctcttgta ttttaaatct
     6601 catttaaatc tttgtctgtg accaacaaag cttaagattt tgtcttcatt taaaactctg
     6661 aatctattcc attgatcatg ttagacgttc aaatgtttaa tggtatagtc tgacctagtg
     6721 aaacaaaatg gatgttgtta ctttttttaa agaatagaat gaaataacta tttcacttgc
     6781 ccaaaatttt aaatattttt tcatctaaac ttgtattgtt tcccatagca gaatgtcaat
     6841 attcacagta catttctgta aagagcaaac caatataatg ttttgagtgt tgaaaaaaat
     6901 tccagatttt tgaagaatta gacaactctt catctacctt atttctagtt cacacagtta
     6961 tctcaaattc cactgaaact aatgggatac tgtcttgtgt agatgccagt tgagtttata
     7021 atgtgaccta gtaaagctgt cttttttgtt gtgttgtatg agtgtcggat catgctttta
     7081 ggaatacttt tattaaaatg gtgtgcattc atgcaaaagg ccaactggct tttgtgaaca
     7141 atagatcttt tctccccttt attttgttct cttgacactt ttgtgaaaat tacctagcct
     7201 gataaaaaca ttttgtaaaa atttgtataa tactgttata aaatatttat aatcccagaa
     7261 aatgttgtgt taaatcttgt gcaaaaacag tatattcaga ataaaagttt atcatttaaa
     7321 gtca
//
