LOCUS       NM_001129836           13795 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens calcium voltage-gated channel subunit alpha1 C
            (CACNA1C), transcript variant 10, mRNA.
ACCESSION   NM_001129836
VERSION     NM_001129836.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 13795)
  AUTHORS   Zhang,X., Liang,X., Cheng,X., Chen,J., Deng,W., Zhang,Y., Cui,L.,
            Cheng,X., Li,X., Yang,C., Ye,B. and Cao,L.
  TITLE     [CACNA1C rs58619945 genotype influences the cortical thickness of
            attention network among patients with Bipolar disorder]
  JOURNAL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 41 (9), 1045-1052 (2024)
   PUBMED   39217481
  REMARK    GeneRIF: [CACNA1C rs58619945 genotype influences the cortical
            thickness of attention network among patients with Bipolar
            disorder].
REFERENCE   2  (bases 1 to 13795)
  AUTHORS   Yang,Y., Zhu,Z., Hui,L. and Sun,P.
  TITLE     Effects of CACNA1C and ANK3 on cognitive function in patients with
            bipolar disorder
  JOURNAL   Prog Neuropsychopharmacol Biol Psychiatry 133, 111016 (2024)
   PUBMED   38657895
  REMARK    GeneRIF: Effects of CACNA1C and ANK3 on cognitive function in
            patients with bipolar disorder.
REFERENCE   3  (bases 1 to 13795)
  AUTHORS   Almodovar-Paya,C., Guardiola-Ripoll,M., Giralt-Lopez,M.,
            Oscoz-Irurozqui,M., Canales-Rodriguez,E.J., Madre,M.,
            Soler-Vidal,J., Ramiro,N., Callado,L.F., Arias,B., Gallego,C.,
            Pomarol-Clotet,E. and Fatjo-Vilas,M.
  TITLE     NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom
            severity through neuroanatomical changes in schizophrenia
  JOURNAL   Brain Struct Funct 229 (5), 1299-1315 (2024)
   PUBMED   38720004
  REMARK    GeneRIF: NRN1 epistasis with BDNF and CACNA1C: mediation effects on
            symptom severity through neuroanatomical changes in schizophrenia.
REFERENCE   4  (bases 1 to 13795)
  AUTHORS   Gao,S., Yao,X., Chen,J., Huang,G., Fan,X., Xue,L., Li,Z., Wu,T.,
            Zheng,Y., Huang,J., Jin,X., Wang,Y., Wang,Z., Yu,Y., Liu,L.,
            Pan,X., Song,C. and Yan,N.
  TITLE     Structural basis for human Cav1.2 inhibition by multiple drugs and
            the neurotoxin calciseptine
  JOURNAL   Cell 186 (24), 5363-5374 (2023)
   PUBMED   37972591
  REMARK    GeneRIF: Structural basis for human Cav1.2 inhibition by multiple
            drugs and the neurotoxin calciseptine.
REFERENCE   5  (bases 1 to 13795)
  AUTHORS   Brugada,R., Campuzano,O., Sarquella-Brugada,G., Brugada,P.,
            Brugada,J. and Hong,K.
  TITLE     Brugada Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301690
REFERENCE   6  (bases 1 to 13795)
  AUTHORS   Napolitano,C. and Priori,S.G.
  TITLE     CACNA1C-Related Disorders
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301577
REFERENCE   7  (bases 1 to 13795)
  AUTHORS   Groffen,A.J., Bikker,H. and Christiaans,I.
  TITLE     Long QT Syndrome Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301308
REFERENCE   8  (bases 1 to 13795)
  AUTHORS   Sun,W., McPherson,J.D., Hoang,D.Q., Wasmuth,J.J., Evans,G.A. and
            Montal,M.
  TITLE     Mapping of a human brain voltage-gated calcium channel to human
            chromosome 12p13-pter
  JOURNAL   Genomics 14 (4), 1092-1094 (1992)
   PUBMED   1335957
REFERENCE   9  (bases 1 to 13795)
  AUTHORS   Powers,P.A., Gregg,R.G. and Hogan,K.
  TITLE     Linkage mapping of the human gene for the alpha 1 subunit of the
            cardiac DHP-sensitive Ca2+ channel (CACNL1A1) to chromosome
            12p13.2-pter using a dinucleotide repeat
  JOURNAL   Genomics 14 (1), 206-207 (1992)
   PUBMED   1330882
REFERENCE   10 (bases 1 to 13795)
  AUTHORS   Soldatov,N.M.
  TITLE     Molecular diversity of L-type Ca2+ channel transcripts in human
            fibroblasts
  JOURNAL   Proc Natl Acad Sci U S A 89 (10), 4628-4632 (1992)
   PUBMED   1316612
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC005342.1, Z34820.1 and
            AC007618.21.
            
            On Aug 13, 2020 this sequence version replaced NM_001129836.1.
            
            Summary: This gene encodes an alpha-1 subunit of a
            voltage-dependent calcium channel. Calcium channels mediate the
            influx of calcium ions into the cell upon membrane polarization.
            The alpha-1 subunit consists of 24 transmembrane segments and forms
            the pore through which ions pass into the cell. The calcium channel
            consists of a complex of alpha-1, alpha-2/delta, beta, and gamma
            subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of
            these proteins, either encoded by different genes or the result of
            alternative splicing of transcripts. The protein encoded by this
            gene binds to and is inhibited by dihydropyridine. Alternative
            splicing results in many transcript variants encoding different
            proteins. Some of the predicted proteins may not produce functional
            ion channel subunits. [provided by RefSeq, Oct 2012].
            
            Transcript Variant: This variant (10), also referred to has HLCC89,
            lacks three alternate in-frame exons, compared to variant 1,
            resulting in a shorter protein (isoform 10), compared to isoform 1.
            This isoform (10) is predicted to form a non-functional calcium
            channel subunit because it contains an aberrant number of
            transmembrane domains.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Z34820.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               AC005342.1         177303-177565
            264-576             AC005342.1         177566-177878
            577-6959            Z34820.1           1-6383
            6960-13794          AC007618.21        774-7608            c
            13795-13795         AC007618.21        773-773             c
FEATURES             Location/Qualifiers
     source          1..13795
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p13.33"
     gene            1..13795
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="calcium voltage-gated channel subunit alpha1 C"
                     /db_xref="GeneID:775"
                     /db_xref="HGNC:HGNC:1390"
                     /db_xref="MIM:114205"
     exon            1..625
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     CDS             577..7044
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="isoform 10 is encoded by transcript variant 10;
                     calcium channel, cardic dihydropyridine-sensitive, alpha-1
                     subunit; DHPR, alpha-1 subunit; voltage-dependent L-type
                     Ca2+ channel alpha 1 subunit; calcium channel,
                     voltage-dependent, L type, alpha 1C subunit; CACNA1C
                     intronic transcript 2; CACNA1C intronic transcript 2
                     (non-protein coding)"
                     /codon_start=1
                     /product="voltage-dependent L-type calcium channel subunit
                     alpha-1C isoform 10"
                     /protein_id="NP_001123308.1"
                     /db_xref="CCDS:CCDS44797.1"
                     /db_xref="GeneID:775"
                     /db_xref="HGNC:HGNC:1390"
                     /db_xref="MIM:114205"
                     /translation="MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIP
                     TPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR
                     ALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLE
                     RVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKA
                     DGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVL
                     FVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKP
                     GWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIG
                     SFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
                     NEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRR
                     WNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLAL
                     FTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL
                     LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEM
                     QTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICG
                     NYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGE
                     SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVG
                     PRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSS
                     ISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL
                     DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIG
                     NIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQP
                     RSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFF
                     IIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIP
                     KNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLF
                     TVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV
                     GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALP
                     YVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQ
                     DIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD
                     NFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP
                     HRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIW
                     KRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
                     QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSY
                     YQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANI
                     NNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAM
                     AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSP
                     KRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR
                     SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT
                     PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIE
                     VTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAG
                     CVRARGRPSEEELQDSRVYVSSL"
     exon            626..947
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1053
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1193
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1333
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1492
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1689
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1793
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1966
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1967..2057
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2084
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2245
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2246..2471
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2679
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..2800
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2915
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2916..3036
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..3106
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3239
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3240..3369
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3370..3429
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3430..3536
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3537..3624
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3625..3732
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3733..3785
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3786..3932
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3933..4134
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4135..4293
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4294..4404
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4405..4488
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4489..4572
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4573..4701
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4702..4767
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4768..4859
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4860..5025
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5026..5153
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5154..5250
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5251..5353
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5354..5455
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5456..5583
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5584..5718
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5719..6071
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6072..6200
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6201..6307
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6308..6411
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6412..6744
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6745..13795
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7974..7979
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AATAGA"
     polyA_site      8004
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="major polyA site"
     regulatory      8688..8693
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AATATA"
     polyA_site      8707
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
     regulatory      8751..8756
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AGTAAA"
     polyA_site      8787
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
     regulatory      13773..13778
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AATAAA"
     polyA_site      13795
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="major polyA site"
ORIGIN      
        1 gtctccctct cgctgcctct gcagaaacag ctcctgccag agcggcgctc ggcgcggcgc
       61 ggcgggcccg gagcggcggc ggcggctctt cctgcctccg cgcccaggag ttgccggctc
      121 cctttgacag cagagagccg ggcaggggcc tcaggaggac tcgctgggag tgggcagagg
      181 cgcctcggcc cctgccggcc caggcgggcc ccgcgcgccc cccgcccctc ctctccgcct
      241 cttctcgccc tgcctctccc gatttatttt ttcaaatggt gtagccgccg gaggtgcggt
      301 gctcagttct tggaaggggc ccggatgtac tgaggatgcg ttacagtttc actcgaggag
      361 gcagtagtgg aaaggagcag tttttggggt ttgatgccat aatgggaatc aggtaatcgt
      421 cggcggggaa gaagaaacgc tgcagaccac ggcttcctcg aatcttgcgc gaaagccgcc
      481 ggcctcggag gagggattaa tccagacccg ccggggggtg ttttcacatt tcttcctctt
      541 cgtggctgct cctcctatta aaaccatttt tggtccatgg tcaatgagaa tacgaggatg
      601 tacattccag aggaaaacca ccaaggttcc aactatggga gcccacgccc cgcccatgcc
      661 aacatgaatg ccaatgcggc agcggggctg gcccctgagc acatccccac cccgggggct
      721 gccctgtcgt ggcaggcggc catcgacgca gcccggcagg ctaagctgat gggcagcgct
      781 ggcaatgcga ccatctccac agtcagctcc acgcagcgga agcggcagca atatgggaaa
      841 cccaagaagc agggcagcac cacggccaca cgcccgcccc gagccctgct ctgcctgacc
      901 ctgaagaacc ccatccggag ggcctgcatc agcattgtcg aatggaaacc atttgaaata
      961 attattttac tgactatttt tgccaattgt gtggccttag cgatctatat tccctttcca
     1021 gaagatgatt ccaacgccac caattccaac ctggaacgag tggaatatct ctttctcata
     1081 atttttacgg tggaagcgtt tttaaaagta atcgcctatg gactcctctt tcaccccaat
     1141 gcctacctcc gcaacggctg gaacctacta gattttataa ttgtggttgt ggggcttttt
     1201 agtgcaattt tagaacaagc aaccaaagca gatggggcaa acgctctcgg agggaaaggg
     1261 gccggatttg atgtgaaggc gctgagggcc ttccgcgtgc tgcgccccct gcggctggtg
     1321 tccggagtcc caagtctcca ggtggtcctg aattccatca tcaaggccat ggtccccctg
     1381 ctgcacatcg ccctgcttgt gctgtttgtc atcatcatct acgccatcat cggcttggag
     1441 ctcttcatgg ggaagatgca caagacctgc tacaaccagg agggcatagc agatgttcca
     1501 gcagaagatg acccttcccc ttgtgcgctg gaaacgggcc acgggcggca gtgccagaac
     1561 ggcacggtgt gcaagcccgg ctgggatggt cccaagcacg gcatcaccaa ctttgacaac
     1621 tttgccttcg ccatgctcac ggtgttccag tgcatcacca tggagggctg gacggacgtg
     1681 ctgtactggg tcaatgatgc cgtaggaagg gactggccct ggatctattt tgttacacta
     1741 atcatcatag ggtcattttt tgtacttaac ttggttctcg gtgtgcttag cggagagttt
     1801 tccaaagaga gggagaaggc caaggcccgg ggagatttcc agaagctgcg ggagaagcag
     1861 cagctagaag aggatctcaa aggctacctg gattggatca ctcaggccga agacatcgat
     1921 cctgagaatg aggacgaagg catggatgag gagaagcccc gaaacatgag catgcccacc
     1981 agtgagaccg agtccgtcaa caccgaaaac gtggctggag gtgacatcga gggagaaaac
     2041 tgcggggcca ggctggccca ccggatctcc aagtcaaagt tcagccgcta ctggcgccgg
     2101 tggaatcggt tctgcagaag gaagtgccgc gccgcagtca agtctaatgt cttctactgg
     2161 ctggtgattt tcctggtgtt cctcaacacg ctcaccattg cctctgagca ctacaaccag
     2221 cccaactggc tcacagaagt ccaagacacg gcaaacaagg ccctgctggc cctgttcacg
     2281 gcagagatgc tcctgaagat gtacagcctg ggcctgcagg cctacttcgt gtccctcttc
     2341 aaccgctttg actgcttcgt cgtgtgtggc ggcatcctgg agaccatcct ggtggagacc
     2401 aagatcatgt ccccactggg catctccgtg ctcagatgcg tccggctgct gaggattttc
     2461 aagatcacga ggtactggaa ctccttgagc aacctggtgg catccttgct gaactctgtg
     2521 cgctccatcg cctccctgct ccttctcctc ttcctcttca tcatcatctt ctccctcctg
     2581 gggatgcagc tctttggagg aaagttcaac tttgatgaga tgcagacccg gaggagcaca
     2641 ttcgataact tcccccagtc cctcctcact gtgtttcaga tcctgaccgg ggaggactgg
     2701 aattcggtga tgtatgatgg gatcatggct tatggcggcc cctcttttcc agggatgtta
     2761 gtctgtattt acttcatcat cctcttcatc tgtggaaact atatcctact gaatgtgttc
     2821 ttggccattg ctgtggacaa cctggctgat gctgagagcc tcacatctgc ccaaaaggag
     2881 gaggaagagg agaaggagag aaagaagctg gccaggactg ccagcccaga gaagaaacaa
     2941 gagttggtgg agaagccggc agtgggggaa tccaaggagg agaagattga gctgaaatcc
     3001 atcacggctg acggagagtc tccacccgcc accaagatca acatggatga cctccagccc
     3061 aatgaaaatg aggataagag cccctacccc aacccagaaa ctacaggaga agaggatgag
     3121 gaggagccag agatgcctgt cggccctcgc ccacgaccac tctctgagct tcaccttaag
     3181 gaaaaggcag tgcccatgcc agaagccagc gcgtttttca tcttcagctc taacaacagg
     3241 tttcgcctcc agtgccaccg cattgtcaat gacacgatct tcaccaacct gatcctcttc
     3301 ttcattctgc tcagcagcat ttccctggct gctgaggacc cggtccagca cacctccttc
     3361 aggaaccata tcctaggcaa tgcagactat gtcttcacta gtatctttac attagaaatt
     3421 atccttaaga tgactgctta tggggctttc ttgcacaagg gttctttctg ccggaactac
     3481 ttcaacatcc tggacctgct ggtggtcagc gtgtccctca tctcctttgg catccagtcc
     3541 agtgcaatca atgtcgtgaa gatcttgcga gtcctgcgag tactcaggcc cctgagggcc
     3601 atcaacaggg ccaaggggct aaagcatgtg gttcagtgtg tgtttgtcgc catccggacc
     3661 atcgggaaca tcgtgattgt caccaccctg ctgcagttca tgtttgcctg catcggggtc
     3721 cagctcttca agggaaagct gtacacctgt tcagacagtt ccaagcagac agaggcggaa
     3781 tgcaagggca actacatcac gtacaaagac ggggaggttg accaccccat catccaaccc
     3841 cgcagctggg agaacagcaa gtttgacttt gacaatgttc tggcagccat gatggccctc
     3901 ttcaccgtct ccaccttcga agggtggcca gagctgctgt accgctccat cgactcccac
     3961 acggaagaca agggccccat ctacaactac cgtgtggaga tctccatctt cttcatcatc
     4021 tacatcatca tcatcgcctt cttcatgatg aacatcttcg tgggcttcgt catcgtcacc
     4081 tttcaggagc agggggagca ggagtacaag aactgtgagc tggacaagaa ccagcgacag
     4141 tgcgtggaat acgccctcaa ggcccggccc ctgcggaggt acatccccaa gaaccagcac
     4201 cagtacaaag tgtggtacgt ggtcaactcc acctacttcg agtacctgat gttcgtcctc
     4261 atcctgctca acaccatctg cctggccatg cagcactacg gccagagctg cctgttcaaa
     4321 atcgccatga acatcctcaa catgctcttc actggcctct tcaccgtgga gatgatcctg
     4381 aagctcattg ccttcaaacc caagggttac tttagtgatc cctggaatgt ttttgacttc
     4441 ctcatcgtaa ttggcagcat aattgacgtc attctcagtg agactaatca ctatttctgt
     4501 gatgcatgga atacatttga cgccttgatt gttgtgggta gcattgttga tatagcaatc
     4561 accgaggtaa acaacgcaga ggaaaactcc cgcatctcca tcaccttctt ccgcctgttc
     4621 cgggtcatgc gtctggtgaa gctgctgagc cgtggggagg gcatccggac gctgctgtgg
     4681 accttcatca agtccttcca ggccctgccc tatgtggccc tcctgatcgt gatgctgttc
     4741 ttcatctacg cggtgatcgg gatgcaggtg tttgggaaaa ttgccctgaa tgataccaca
     4801 gagatcaacc ggaacaacaa ctttcagacc ttcccccagg ccgtgctgct cctcttcagg
     4861 tgtgccaccg gggaggcctg gcaggacatc atgctggcct gcatgccagg caagaagtgt
     4921 gccccagagt ccgagcccag caacagcacg gagggtgaaa caccctgtgg tagcagcttt
     4981 gctgtcttct acttcatcag cttctacatg ctctgtgcct tcctgatcat caacctcttt
     5041 gtagctgtca tcatggacaa ctttgactac ctgacaaggg actggtccat ccttggtccc
     5101 caccacctgg atgagtttaa aagaatctgg gcagagtatg accctgaagc caagggtcgt
     5161 atcaaacacc tggatgtggt gaccctcctc cggcggattc agccgccact aggttttggg
     5221 aagctgtgcc ctcaccgcgt ggcttgcaaa cgcctggtct ccatgaacat gcctctgaac
     5281 agcgacggga cagtcatgtt caatgccacc ctgtttgccc tggtcaggac ggccctgagg
     5341 atcaaaacag aagggaacct agaacaagcc aatgaggagc tgcgggcgat catcaagaag
     5401 atctggaagc ggaccagcat gaagctgctg gaccaggtgg tgccccctgc aggtgatgat
     5461 gaggtcaccg ttggcaagtt ctacgccacg ttcctgatcc aggagtactt ccggaagttc
     5521 aagaagcgca aagagcaggg ccttgtgggc aagccctccc agaggaacgc gctgtctctg
     5581 caggctggct tgcgcacact gcatgacatc gggcctgaga tccgacgggc catctctgga
     5641 gatctcaccg ctgaggagga gctggacaag gccatgaagg aggctgtgtc cgctgcttct
     5701 gaagatgaca tcttcaggag ggccggtggc ctgttcggca accacgtcag ctactaccaa
     5761 agcgacggcc ggagcgcctt cccccagacc ttcaccactc agcgcccgct gcacatcaac
     5821 aaggcgggca gcagccaggg cgacactgag tcgccatccc acgagaagct ggtggactcc
     5881 accttcaccc cgagcagcta ctcgtccacc ggctccaacg ccaacatcaa caacgccaac
     5941 aacaccgccc tgggtcgcct ccctcgcccc gccggctacc ccagcacggt cagcactgtg
     6001 gagggccacg ggcccccctt gtcccctgcc atccgggtgc aggaggtggc gtggaagctc
     6061 agctccaaca ggtgccactc ccgggagagc caggcagcca tggcgggtca ggaggagacg
     6121 tctcaggatg agacctatga agtgaagatg aaccatgaca cggaggcctg cagtgagccc
     6181 agcctgctct ccacagagat gctctcctac caggatgacg aaaatcggca actgacgctc
     6241 ccagaggagg acaagaggga catccggcaa tctccgaaga ggggtttcct ccgctctgcc
     6301 tcactaggtc gaagggcctc cttccacctg gaatgtctga agcgacagaa ggaccgaggg
     6361 ggagacatct ctcagaagac agtcctgccc ttgcatctgg ttcatcatca ggcattggca
     6421 gtggcaggcc tgagccccct cctccagaga agccattccc ctgcctcatt ccctaggcct
     6481 tttgccaccc caccagccac acctggcagc cgaggctggc ccccacagcc cgtccccacc
     6541 ctgcggcttg agggggtcga gtccagtgag aaactcaaca gcagcttccc atccatccac
     6601 tgcggctcct gggctgagac cacccccggt ggcgggggca gcagcgccgc ccggagagtc
     6661 cggcccgtct ccctcatggt gcccagccag gctggggccc cagggaggca gttccacggc
     6721 agtgccagca gcctggtgga agcggtcttg atttcagaag gactggggca gtttgctcaa
     6781 gatcccaagt tcatcgaggt caccacccag gagctggccg acgcctgcga catgaccata
     6841 gaggagatgg agagcgcggc cgacaacatc ctcagcgggg gcgccccaca gagccccaat
     6901 ggcgccctct taccctttgt gaactgcagg gacgcggggc aggaccgagc cgggggcgaa
     6961 gaggacgcgg gctgtgtgcg cgcgcggggt cgaccgagtg aggaggagct ccaggacagc
     7021 agggtctacg tcagcagcct gtagtgggcg ctgccagatg cgggcttttt tttatttgtt
     7081 tcaatgttcc taatgggttc gtttcagaag tgcctcactg ttctcgtgac ctggagttaa
     7141 ccggaacagc gtcttcattc atttctgttg ggaccagacg cggagcctgg gtgcgcgagc
     7201 cgccctccgg gaggaaggcg cccggctgcg tctgcagagg cggggagagg aggcggcgag
     7261 ggtcccgggg cgcgaggaag gcgcctgccc tctcccagct cgcaggcccc gggcccggcc
     7321 gcgcctccgc ggggagagca ccccggcttc ccgcgcgccc tcaccaaaag gaccctacag
     7381 caaacgggtg tctttcgact ctgcttgtag aaaccatttg cacatattct gtacgagcct
     7441 cgctgtctcc ctagagccag ggccctgcgg atttggagaa gggagcgggg caggacttcc
     7501 aggaggaccc caacccggcc cggagaggga ggaggaggcc tccaggggcg cggagctctg
     7561 gggatgggcg tcgggccggc agtggtgcgg ctcactccgt ccctgcccac ctgcgacggg
     7621 atcccccgac cggcacgggc cacgccgagc tcccggccag ccgccggccc gcaggcagcg
     7681 cgagggagga gctgcgccgc cggctccgcc caaccaggtg gtgctgagct tccgctgagc
     7741 gctcttttgt tttgtggttt gacacttttc ttgacagcat gttgcagttt cttttcggtt
     7801 ttggtttttt ttaaatgttt tattttgctt tcccagcggg aggggaggaa gaagagtgtt
     7861 tacaaagtcc tgtagccccc tcacctttct gttttcactt ttgccaatgt acatcgggtt
     7921 tggttttctt gtattattta aacggttgtg gtttcctttt tccacggagg ttcaatagaa
     7981 gccgctgcag gagagtttta ccaaccattg tgtatgccca ataatttgtt atcatttcct
     8041 taggtagtaa cctatttttg ttctggtttg gttcggttat ctaatggaaa ggtaactggc
     8101 aatgcacttg atgtggtctt gcacatgtgg gtgatagagt tgggttcctt tttatgctgg
     8161 gtgtacaggt gggtttggga gagaggagca tgcgcgagag agtctccgag tgtgtgcgac
     8221 gcgtgtgtgt gtggtgggtt gtctgtgtgc atatgtcctg cccgtgtata tgcacccaca
     8281 ccatgtgccc gtgcacacca gtgactacgc agtcccccct ttctggttta gctgtgggaa
     8341 gatctgaatc tggggccgtt tgaaagcaaa aacaaaccac tgtctctgct tctgaaacgg
     8401 gaatcagtaa ctctttgcat tttctgtccc acaagatatg caaaaacaat gcaataatat
     8461 tcatttaaaa atacaattgt gagttgtgtt ggcattaaaa ctgtatttta aaaaaagaca
     8521 gaaatttaag ggaaaaacac aagaaggcat tttgcttcaa tatattccgt gtaatgtttt
     8581 attgcattga taatgtttct gttgaagaaa ccgttatact tgaattcagg tcagtttcag
     8641 tatttttcaa atattttttt aaaactgaat tgcaattgtg ccaagcgaat ataatgaatt
     8701 gaattaagtt ggttttcgga ttcacttctt gtatattttg ctgcatgtaa agtaaatcat
     8761 tttgtatttg gagtgtgaca agctttacct ttgaactcaa gtgcttttct atatgtggtt
     8821 gggggaaagg gaacaagttt tctttagttt gcacaatgag caaaggtatc accagtgtag
     8881 tcattattct gctctccaca aacaggtttg gacattactg ttttgcatat cttgtgtttg
     8941 cttacatttc cctcaatttt tccaaaatcg tttgctgggt atgtttgtac cgcctcttgc
     9001 tgtgagagac caggacctat tttattccag tcttcactct gtccactctg ctctggtcat
     9061 ctgatttggt acttctccaa gaacagccct tcactgtgag gtgcagggag gcgttctgat
     9121 gagccctcag tcactgggcc gtcatccgca tcccccatgg aagaggtagc tggctttccc
     9181 ttcccttcca ccacacggaa ttttctcttt ggcttcctta ggaaagtgta cactaaccgg
     9241 gaggataaaa ttaaagtcag gctgcttgga gggaggggca tcctcacttc cggattcttg
     9301 ttgctctacc caacaaggac agcaggggct cgagaaagga actggtgaaa ccctgatcca
     9361 tctgaaagtc aactctgcgt gctcctttct ccatcccttc ctcactctgg agcagccttt
     9421 ccttcaggct tgccctaatg tttgggctgc cggggagggg gccaggacaa gggaagaggc
     9481 atccggagct cacagtgggg gtgggaacag atttttgtgg gggcatctct aatgctcact
     9541 tatatctccc tagaacatca ctcttttggt gctgtgtcct tcaaatgtat gtcaacagtg
     9601 gtggctgaaa agggactgct ttggggaaaa caggacccaa ccattcaccc agaattgacc
     9661 cattaaatct cttccagtcc tagtgttccc tgagcccctc ttggcacata tataagtaag
     9721 ctagaaatta caataaggga cagtccattc ctctatgaca gcttgctgga ctgattcatg
     9781 acaaagtgga gaaatgtact caatactccc cggttaacac agtctagaaa cagagtttct
     9841 ttatggatat ccacacccaa gtcatccaaa ctttcttgat tccttttcac tgccatcaag
     9901 gtcctctaga aattgagttt aggtatcatc ctttgaaaag ttcccaagat ttctaccagg
     9961 aggtacacac aggcgttccc tgtctagggc aggaggacta tcctagcttg accttctgat
    10021 ccactagaat aagactggcg tatgatgcct gtcatcagaa cagactggca caagtagtga
    10081 catcaatgaa ccacagcaca atcttccaag tgatgtctac tctccaccta aaatggaatt
    10141 ttccccatga ccttgtaaaa cataattgtc acatcttcca tacccctcct gacagccccc
    10201 aagtgtcagg agaaaacagt caggggctaa gggcccaagg gacttgaaga aacaacagtt
    10261 taaggtctgc agtttggtca acttaattct tgtcctccga ccagccctgc ctctttcatt
    10321 tccagacctt ggagaatttt tcccagcttt gattcagaag gtactagtta taaccccttt
    10381 ccttcttctt aatccaatag gcctcactct cactgggaaa tccactcaaa ggaacaaggc
    10441 aatgtctctc attctatttc ccagttccaa attccaggtg cttgtctgga gtgaagctac
    10501 ccgttacttt ctcccagctt ttctccaccc agcatgtctc ctgcccatgc agctgaagac
    10561 agtggggcaa cctcaggaga agcagacctt tccatgccca agttcatctc ctgagcaaca
    10621 gtgacaccta gaaaatgagg actttggaag tcacccaaaa gatggtggct actttatgga
    10681 gtcctgaaga tacacagcca ccactcctaa aggcaaagaa agaaaacacg aatgtaggtc
    10741 agggatagag tggaaccctg gtcatcgggg tttttagcct catcgtggga aaggtggtaa
    10801 aggaggatga tggcatctcc atccctagag gccaagaatt gaaatatcat tgtcaaggat
    10861 tagaaacaat tcagcaaaga ggccacaaaa agggcctgct gactcccaga agacctcttt
    10921 aaaccccagg ggaggcaaat acttgctgat ggagtctggg ccgtttccat attttaaaga
    10981 agacctgcct ctggggcaaa tgtcagcaca gagaggactg ggaggagaat ggaggcaaga
    11041 aaagggcata ttttgactcc ctctgtgcct cttcccagtt catggaagga tgtgttcagc
    11101 ttacccaccc acagtgacca gtgtggtgga gccgctgaca tctcaaggat ctatttggga
    11161 aggtgagaag agtactcatt ccatctgggg gtgttgttcc agccacatca gcctacctgg
    11221 tgggatgtgg gggtgtctgc caccctgtcc cccctctgct gatgtccctc ccctcaggct
    11281 gtccaggtgc cacctgacac aggctgctgt gcaaagacag gcggggaagc ccaaacctca
    11341 ctcccaggga ggccctcagc cgccagagtc caggttctcc agaggctacg atttgaggag
    11401 gttgaggggg aagacaggag ggaaagaaaa gtcctacaac tgtcaggaat ggggcacctt
    11461 tccctgtccc taagcaaagc tccctcttcc cactgccctc cccagcccca gctccctgtc
    11521 ctccccaaca cctagtgaga aagacggtgc gtggaaggga gtcccatggg cagatgctta
    11581 cacgacctct ttgtgaagcc tcttctgggt ttaacttcat tcatcaattt attcttatgt
    11641 caaagcaatg aaacttttct ttctggagcc agataccaat acaacaggtg aacgggtttc
    11701 tgccacatct ctacattgac gggggatgct tgaacaaccc ccctcactac acagacacac
    11761 accgttaagg cacaagggct ggggttgagc tctagatgag ggactttcct gctcctgcaa
    11821 gggtgagcac tgtatacaca gacaaggagg gtgcagtaga gtgactccct tggatggaag
    11881 tagtaccatc agaacctact attattatga cataaattct atttacatac attgagagaa
    11941 tactacaatc aacacttttt cctgggatga ctttaagagg tttgagccac agcacctgaa
    12001 gtggcaaaga tccatggtct ttgtagggta ttagagaact cttccagtca cctctgaaag
    12061 cactctagat cttgcagctg agtggatgaa gtgtaacaaa tctgttgcac gctgagagga
    12121 gtcagaatta gcatttttca tgaaagttcc ccacgtctct actaagaatg aggaagaaaa
    12181 gactaagact aggtaattac acagaggctt gaaatgttac atcaccagag ccaagtcctc
    12241 tcccttcaga tcagttactg gctgctacac agggacaccc ccaccttttc agggcatccc
    12301 atgcactcca cttctcagga tctaaggaat ttgactttgt agggatccca gaaagggcac
    12361 tgtgccactt cccctggtgt gaatcagaca tacattgtac attcatttct aaaattcact
    12421 catgcacctc aaaccaaggt cattatccaa aaaaaaaaaa aaaaagctct gggtggaaga
    12481 gtttgtaagt tttaagagag ggtcatttct atgtgaggaa atgcagaaat ggacagaatg
    12541 attcttattc actgtttggg tctggagaat tcccattgtg gaaatcttag agatctcaag
    12601 tttattacca agggaataag gaaaaaaagg tgagcaggca ccaggccaag cagtggctcc
    12661 cttgccaagg aacctgaggc tgcaggtttc agggaccccc ttgaagaaac ctctcctggc
    12721 cattggccag gagaaaagag aagtctctcc tgtagagtca caagagaagc aaaagagggt
    12781 gggtcactgg gtcctggaca tagcccccaa ccccaagact tcccaatatg gagaaactac
    12841 accaatgttt aaaaggggaa aaggaaagaa cttgtacatc aagggaagat gatttgtaaa
    12901 cacacagtcc tgtgcagaaa gatccccttc aggaggtgtc tccagcatcc caaagctgtg
    12961 cgcaccttct cttttcctgc ctcaggccac ctatgcatcc agctgcagcc catacccaca
    13021 cctgaaatcc atctcttgaa tcccagccag gttatatacc accccattgc catgtcctgt
    13081 cctggccaga atgcatgctg ttcccccaag cctcgtggga gtgaggccat gggaaacaga
    13141 gatgagcatg tctggacaag tctgtgatgg tagtggatga gaataaccca tggcaaaaca
    13201 cgcacattca ttaagaaata gggcgacaga ttccccgttg gtgaagcact gaaaggtcta
    13261 ttactctcat aatattgctg ttttatttta atccaccaga gctaccatgc aaaactttcc
    13321 tcctgtgaaa cgctccagat aaagctcctc taatctcccc ttccctcatg tcctccagct
    13381 caaacccacc ttcatccccc aaaccaatct gtatcatgcc tgttatcaga gaggcacaga
    13441 aagatgggca gtgcctccgt tgtcaccatt ccccacaccc ctacacaccc ccacaccctc
    13501 ccctccaggc tccacgactt cacagtctta ctgttgtaaa tatcattgta cagtttgtaa
    13561 tcctcaaata atcccattgt cagaggcctc gcctgatggg ccttctcacc ctcgagaaag
    13621 gccagggaat ctagaagggg caacccttca aggagagctt cagggtcatc tctgtgtgag
    13681 acactattgt atattcctgt aagattgcat ttttatctaa ggaatgatgt tatttaaaaa
    13741 acaaacaaaa aacacaaaaa ataagaattg caaataaatt tcttaacaat gtcta
//
