LOCUS       NM_001129835           13801 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens calcium voltage-gated channel subunit alpha1 C
            (CACNA1C), transcript variant 9, mRNA.
ACCESSION   NM_001129835
VERSION     NM_001129835.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 13801)
  AUTHORS   Zhang,X., Liang,X., Cheng,X., Chen,J., Deng,W., Zhang,Y., Cui,L.,
            Cheng,X., Li,X., Yang,C., Ye,B. and Cao,L.
  TITLE     [CACNA1C rs58619945 genotype influences the cortical thickness of
            attention network among patients with Bipolar disorder]
  JOURNAL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 41 (9), 1045-1052 (2024)
   PUBMED   39217481
  REMARK    GeneRIF: [CACNA1C rs58619945 genotype influences the cortical
            thickness of attention network among patients with Bipolar
            disorder].
REFERENCE   2  (bases 1 to 13801)
  AUTHORS   Yang,Y., Zhu,Z., Hui,L. and Sun,P.
  TITLE     Effects of CACNA1C and ANK3 on cognitive function in patients with
            bipolar disorder
  JOURNAL   Prog Neuropsychopharmacol Biol Psychiatry 133, 111016 (2024)
   PUBMED   38657895
  REMARK    GeneRIF: Effects of CACNA1C and ANK3 on cognitive function in
            patients with bipolar disorder.
REFERENCE   3  (bases 1 to 13801)
  AUTHORS   Almodovar-Paya,C., Guardiola-Ripoll,M., Giralt-Lopez,M.,
            Oscoz-Irurozqui,M., Canales-Rodriguez,E.J., Madre,M.,
            Soler-Vidal,J., Ramiro,N., Callado,L.F., Arias,B., Gallego,C.,
            Pomarol-Clotet,E. and Fatjo-Vilas,M.
  TITLE     NRN1 epistasis with BDNF and CACNA1C: mediation effects on symptom
            severity through neuroanatomical changes in schizophrenia
  JOURNAL   Brain Struct Funct 229 (5), 1299-1315 (2024)
   PUBMED   38720004
  REMARK    GeneRIF: NRN1 epistasis with BDNF and CACNA1C: mediation effects on
            symptom severity through neuroanatomical changes in schizophrenia.
REFERENCE   4  (bases 1 to 13801)
  AUTHORS   Gao,S., Yao,X., Chen,J., Huang,G., Fan,X., Xue,L., Li,Z., Wu,T.,
            Zheng,Y., Huang,J., Jin,X., Wang,Y., Wang,Z., Yu,Y., Liu,L.,
            Pan,X., Song,C. and Yan,N.
  TITLE     Structural basis for human Cav1.2 inhibition by multiple drugs and
            the neurotoxin calciseptine
  JOURNAL   Cell 186 (24), 5363-5374 (2023)
   PUBMED   37972591
  REMARK    GeneRIF: Structural basis for human Cav1.2 inhibition by multiple
            drugs and the neurotoxin calciseptine.
REFERENCE   5  (bases 1 to 13801)
  AUTHORS   Brugada,R., Campuzano,O., Sarquella-Brugada,G., Brugada,P.,
            Brugada,J. and Hong,K.
  TITLE     Brugada Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301690
REFERENCE   6  (bases 1 to 13801)
  AUTHORS   Napolitano,C. and Priori,S.G.
  TITLE     CACNA1C-Related Disorders
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301577
REFERENCE   7  (bases 1 to 13801)
  AUTHORS   Groffen,A.J., Bikker,H. and Christiaans,I.
  TITLE     Long QT Syndrome Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301308
REFERENCE   8  (bases 1 to 13801)
  AUTHORS   Sun,W., McPherson,J.D., Hoang,D.Q., Wasmuth,J.J., Evans,G.A. and
            Montal,M.
  TITLE     Mapping of a human brain voltage-gated calcium channel to human
            chromosome 12p13-pter
  JOURNAL   Genomics 14 (4), 1092-1094 (1992)
   PUBMED   1335957
REFERENCE   9  (bases 1 to 13801)
  AUTHORS   Powers,P.A., Gregg,R.G. and Hogan,K.
  TITLE     Linkage mapping of the human gene for the alpha 1 subunit of the
            cardiac DHP-sensitive Ca2+ channel (CACNL1A1) to chromosome
            12p13.2-pter using a dinucleotide repeat
  JOURNAL   Genomics 14 (1), 206-207 (1992)
   PUBMED   1330882
REFERENCE   10 (bases 1 to 13801)
  AUTHORS   Soldatov,N.M.
  TITLE     Molecular diversity of L-type Ca2+ channel transcripts in human
            fibroblasts
  JOURNAL   Proc Natl Acad Sci U S A 89 (10), 4628-4632 (1992)
   PUBMED   1316612
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC005342.1, Z74996.1 and
            AC007618.21.
            
            On Aug 13, 2020 this sequence version replaced NM_001129835.1.
            
            Summary: This gene encodes an alpha-1 subunit of a
            voltage-dependent calcium channel. Calcium channels mediate the
            influx of calcium ions into the cell upon membrane polarization.
            The alpha-1 subunit consists of 24 transmembrane segments and forms
            the pore through which ions pass into the cell. The calcium channel
            consists of a complex of alpha-1, alpha-2/delta, beta, and gamma
            subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of
            these proteins, either encoded by different genes or the result of
            alternative splicing of transcripts. The protein encoded by this
            gene binds to and is inhibited by dihydropyridine. Alternative
            splicing results in many transcript variants encoding different
            proteins. Some of the predicted proteins may not produce functional
            ion channel subunits. [provided by RefSeq, Oct 2012].
            
            Transcript Variant: This variant (9), also referred to has HLCC72,
            lacks three alternate in-frame exons and uses an alternate in-frame
            splice site in the 3' coding region, compared to variant 1,
            resulting in a shorter protein (isoform 9), compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Z74996.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2147975, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               AC005342.1         177303-177565
            264-576             AC005342.1         177566-177878
            577-6965            Z74996.1           1-6389
            6966-13800          AC007618.21        774-7608            c
            13801-13801         AC007618.21        773-773             c
FEATURES             Location/Qualifiers
     source          1..13801
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p13.33"
     gene            1..13801
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="calcium voltage-gated channel subunit alpha1 C"
                     /db_xref="GeneID:775"
                     /db_xref="HGNC:HGNC:1390"
                     /db_xref="MIM:114205"
     exon            1..625
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     CDS             577..7050
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="isoform 9 is encoded by transcript variant 9;
                     calcium channel, cardic dihydropyridine-sensitive, alpha-1
                     subunit; DHPR, alpha-1 subunit; voltage-dependent L-type
                     Ca2+ channel alpha 1 subunit; calcium channel,
                     voltage-dependent, L type, alpha 1C subunit; CACNA1C
                     intronic transcript 2; CACNA1C intronic transcript 2
                     (non-protein coding)"
                     /codon_start=1
                     /product="voltage-dependent L-type calcium channel subunit
                     alpha-1C isoform 9"
                     /protein_id="NP_001123307.1"
                     /db_xref="CCDS:CCDS44799.1"
                     /db_xref="GeneID:775"
                     /db_xref="HGNC:HGNC:1390"
                     /db_xref="MIM:114205"
                     /translation="MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIP
                     TPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR
                     ALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLE
                     RVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKA
                     DGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVL
                     FVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKP
                     GWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIG
                     SFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
                     NEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRR
                     WNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLAL
                     FTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL
                     LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEM
                     QTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICG
                     NYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGE
                     SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVG
                     PRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSS
                     ISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL
                     DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIG
                     NIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQP
                     RSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFF
                     IIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIP
                     KNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLF
                     TVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN
                     SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIG
                     MQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESE
                     PSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHL
                     DEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNS
                     DGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKK
                     IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNAL
                     SLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHV
                     SYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNA
                     NINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQA
                     AMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ
                     SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL
                     QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAE
                     TTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKF
                     IEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
                     AGCVRARGRPSEEELQDSRVYVSSL"
     exon            626..947
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1053
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1193
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..1333
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1492
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1689
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1793
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1966
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            1967..2057
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2084
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2245
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2246..2471
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2472..2679
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..2800
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2915
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            2916..3036
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..3106
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3239
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3240..3369
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3370..3429
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3430..3536
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3537..3624
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3625..3732
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3733..3785
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3786..3932
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            3933..4134
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4135..4293
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4294..4404
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4405..4488
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4489..4521
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4522..4650
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4651..4716
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4717..4808
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4809..4974
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            4975..5102
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5103..5199
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5200..5302
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5303..5461
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5462..5589
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5590..5724
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            5725..6077
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6078..6206
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6207..6313
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6314..6417
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6418..6750
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     exon            6751..13801
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7980..7985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AATAGA"
     polyA_site      8010
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="major polyA site"
     regulatory      8694..8699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AATATA"
     polyA_site      8713
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
     regulatory      8757..8762
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AGTAAA"
     polyA_site      8793
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
     regulatory      13779..13784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="hexamer: AATAAA"
     polyA_site      13801
                     /gene="CACNA1C"
                     /gene_synonym="CACH2; CACN2; CACNA1C-IT2; CACNL1A1;
                     CaV1.2; CCHL1A1; LQT8; NEDHLSS; TS; TS. LQT8"
                     /note="major polyA site"
ORIGIN      
        1 gtctccctct cgctgcctct gcagaaacag ctcctgccag agcggcgctc ggcgcggcgc
       61 ggcgggcccg gagcggcggc ggcggctctt cctgcctccg cgcccaggag ttgccggctc
      121 cctttgacag cagagagccg ggcaggggcc tcaggaggac tcgctgggag tgggcagagg
      181 cgcctcggcc cctgccggcc caggcgggcc ccgcgcgccc cccgcccctc ctctccgcct
      241 cttctcgccc tgcctctccc gatttatttt ttcaaatggt gtagccgccg gaggtgcggt
      301 gctcagttct tggaaggggc ccggatgtac tgaggatgcg ttacagtttc actcgaggag
      361 gcagtagtgg aaaggagcag tttttggggt ttgatgccat aatgggaatc aggtaatcgt
      421 cggcggggaa gaagaaacgc tgcagaccac ggcttcctcg aatcttgcgc gaaagccgcc
      481 ggcctcggag gagggattaa tccagacccg ccggggggtg ttttcacatt tcttcctctt
      541 cgtggctgct cctcctatta aaaccatttt tggtccatgg tcaatgagaa tacgaggatg
      601 tacattccag aggaaaacca ccaaggttcc aactatggga gcccacgccc cgcccatgcc
      661 aacatgaatg ccaatgcggc agcggggctg gcccctgagc acatccccac cccgggggct
      721 gccctgtcgt ggcaggcggc catcgacgca gcccggcagg ctaagctgat gggcagcgct
      781 ggcaatgcga ccatctccac agtcagctcc acgcagcgga agcggcagca atatgggaaa
      841 cccaagaagc agggcagcac cacggccaca cgcccgcccc gagccctgct ctgcctgacc
      901 ctgaagaacc ccatccggag ggcctgcatc agcattgtcg aatggaaacc atttgaaata
      961 attattttac tgactatttt tgccaattgt gtggccttag cgatctatat tccctttcca
     1021 gaagatgatt ccaacgccac caattccaac ctggaacgag tggaatatct ctttctcata
     1081 atttttacgg tggaagcgtt tttaaaagta atcgcctatg gactcctctt tcaccccaat
     1141 gcctacctcc gcaacggctg gaacctacta gattttataa ttgtggttgt ggggcttttt
     1201 agtgcaattt tagaacaagc aaccaaagca gatggggcaa acgctctcgg agggaaaggg
     1261 gccggatttg atgtgaaggc gctgagggcc ttccgcgtgc tgcgccccct gcggctggtg
     1321 tccggagtcc caagtctcca ggtggtcctg aattccatca tcaaggccat ggtccccctg
     1381 ctgcacatcg ccctgcttgt gctgtttgtc atcatcatct acgccatcat cggcttggag
     1441 ctcttcatgg ggaagatgca caagacctgc tacaaccagg agggcatagc agatgttcca
     1501 gcagaagatg acccttcccc ttgtgcgctg gaaacgggcc acgggcggca gtgccagaac
     1561 ggcacggtgt gcaagcccgg ctgggatggt cccaagcacg gcatcaccaa ctttgacaac
     1621 tttgccttcg ccatgctcac ggtgttccag tgcatcacca tggagggctg gacggacgtg
     1681 ctgtactggg tcaatgatgc cgtaggaagg gactggccct ggatctattt tgttacacta
     1741 atcatcatag ggtcattttt tgtacttaac ttggttctcg gtgtgcttag cggagagttt
     1801 tccaaagaga gggagaaggc caaggcccgg ggagatttcc agaagctgcg ggagaagcag
     1861 cagctagaag aggatctcaa aggctacctg gattggatca ctcaggccga agacatcgat
     1921 cctgagaatg aggacgaagg catggatgag gagaagcccc gaaacatgag catgcccacc
     1981 agtgagaccg agtccgtcaa caccgaaaac gtggctggag gtgacatcga gggagaaaac
     2041 tgcggggcca ggctggccca ccggatctcc aagtcaaagt tcagccgcta ctggcgccgg
     2101 tggaatcggt tctgcagaag gaagtgccgc gccgcagtca agtctaatgt cttctactgg
     2161 ctggtgattt tcctggtgtt cctcaacacg ctcaccattg cctctgagca ctacaaccag
     2221 cccaactggc tcacagaagt ccaagacacg gcaaacaagg ccctgctggc cctgttcacg
     2281 gcagagatgc tcctgaagat gtacagcctg ggcctgcagg cctacttcgt gtccctcttc
     2341 aaccgctttg actgcttcgt cgtgtgtggc ggcatcctgg agaccatcct ggtggagacc
     2401 aagatcatgt ccccactggg catctccgtg ctcagatgcg tccggctgct gaggattttc
     2461 aagatcacga ggtactggaa ctccttgagc aacctggtgg catccttgct gaactctgtg
     2521 cgctccatcg cctccctgct ccttctcctc ttcctcttca tcatcatctt ctccctcctg
     2581 gggatgcagc tctttggagg aaagttcaac tttgatgaga tgcagacccg gaggagcaca
     2641 ttcgataact tcccccagtc cctcctcact gtgtttcaga tcctgaccgg ggaggactgg
     2701 aattcggtga tgtatgatgg gatcatggct tatggcggcc cctcttttcc agggatgtta
     2761 gtctgtattt acttcatcat cctcttcatc tgtggaaact atatcctact gaatgtgttc
     2821 ttggccattg ctgtggacaa cctggctgat gctgagagcc tcacatctgc ccaaaaggag
     2881 gaggaagagg agaaggagag aaagaagctg gccaggactg ccagcccaga gaagaaacaa
     2941 gagttggtgg agaagccggc agtgggggaa tccaaggagg agaagattga gctgaaatcc
     3001 atcacggctg acggagagtc tccacccgcc accaagatca acatggatga cctccagccc
     3061 aatgaaaatg aggataagag cccctacccc aacccagaaa ctacaggaga agaggatgag
     3121 gaggagccag agatgcctgt cggccctcgc ccacgaccac tctctgagct tcaccttaag
     3181 gaaaaggcag tgcccatgcc agaagccagc gcgtttttca tcttcagctc taacaacagg
     3241 tttcgcctcc agtgccaccg cattgtcaat gacacgatct tcaccaacct gatcctcttc
     3301 ttcattctgc tcagcagcat ttccctggct gctgaggacc cggtccagca cacctccttc
     3361 aggaaccata tcctaggcaa tgcagactat gtcttcacta gtatctttac attagaaatt
     3421 atccttaaga tgactgctta tggggctttc ttgcacaagg gttctttctg ccggaactac
     3481 ttcaacatcc tggacctgct ggtggtcagc gtgtccctca tctcctttgg catccagtcc
     3541 agtgcaatca atgtcgtgaa gatcttgcga gtcctgcgag tactcaggcc cctgagggcc
     3601 atcaacaggg ccaaggggct aaagcatgtg gttcagtgtg tgtttgtcgc catccggacc
     3661 atcgggaaca tcgtgattgt caccaccctg ctgcagttca tgtttgcctg catcggggtc
     3721 cagctcttca agggaaagct gtacacctgt tcagacagtt ccaagcagac agaggcggaa
     3781 tgcaagggca actacatcac gtacaaagac ggggaggttg accaccccat catccaaccc
     3841 cgcagctggg agaacagcaa gtttgacttt gacaatgttc tggcagccat gatggccctc
     3901 ttcaccgtct ccaccttcga agggtggcca gagctgctgt accgctccat cgactcccac
     3961 acggaagaca agggccccat ctacaactac cgtgtggaga tctccatctt cttcatcatc
     4021 tacatcatca tcatcgcctt cttcatgatg aacatcttcg tgggcttcgt catcgtcacc
     4081 tttcaggagc agggggagca ggagtacaag aactgtgagc tggacaagaa ccagcgacag
     4141 tgcgtggaat acgccctcaa ggcccggccc ctgcggaggt acatccccaa gaaccagcac
     4201 cagtacaaag tgtggtacgt ggtcaactcc acctacttcg agtacctgat gttcgtcctc
     4261 atcctgctca acaccatctg cctggccatg cagcactacg gccagagctg cctgttcaaa
     4321 atcgccatga acatcctcaa catgctcttc actggcctct tcaccgtgga gatgatcctg
     4381 aagctcattg ccttcaaacc caagcactat ttctgtgatg catggaatac atttgacgcc
     4441 ttgattgttg tgggtagcat tgttgatata gcaatcaccg aggtaaaccc agctgaacat
     4501 acccaatgct ctccctctat gaacgcagag gaaaactccc gcatctccat caccttcttc
     4561 cgcctgttcc gggtcatgcg tctggtgaag ctgctgagcc gtggggaggg catccggacg
     4621 ctgctgtgga ccttcatcaa gtccttccag gccctgccct atgtggccct cctgatcgtg
     4681 atgctgttct tcatctacgc ggtgatcggg atgcaggtgt ttgggaaaat tgccctgaat
     4741 gataccacag agatcaaccg gaacaacaac tttcagacct tcccccaggc cgtgctgctc
     4801 ctcttcaggt gtgccaccgg ggaggcctgg caggacatca tgctggcctg catgccaggc
     4861 aagaagtgtg ccccagagtc cgagcccagc aacagcacgg agggtgaaac accctgtggt
     4921 agcagctttg ctgtcttcta cttcatcagc ttctacatgc tctgtgcctt cctgatcatc
     4981 aacctctttg tagctgtcat catggacaac tttgactacc tgacaaggga ctggtccatc
     5041 cttggtcccc accacctgga tgagtttaaa agaatctggg cagagtatga ccctgaagcc
     5101 aagggtcgta tcaaacacct ggatgtggtg accctcctcc ggcggattca gccgccacta
     5161 ggttttggga agctgtgccc tcaccgcgtg gcttgcaaac gcctggtctc catgaacatg
     5221 cctctgaaca gcgacgggac agtcatgttc aatgccaccc tgtttgccct ggtcaggacg
     5281 gccctgagga tcaaaacaga agagggaccc agcccatcag aggcccacca aggggctgag
     5341 gatcctttcc gccctgcagg gaacctagaa caagccaatg aggagctgcg ggcgatcatc
     5401 aagaagatct ggaagcggac cagcatgaag ctgctggacc aggtggtgcc ccctgcaggt
     5461 gatgatgagg tcaccgttgg caagttctac gccacgttcc tgatccagga gtacttccgg
     5521 aagttcaaga agcgcaaaga gcagggcctt gtgggcaagc cctcccagag gaacgcgctg
     5581 tctctgcagg ctggcttgcg cacactgcat gacatcgggc ctgagatccg acgggccatc
     5641 tctggagatc tcaccgctga ggaggagctg gacaaggcca tgaaggaggc tgtgtccgct
     5701 gcttctgaag atgacatctt caggagggcc ggtggcctgt tcggcaacca cgtcagctac
     5761 taccaaagcg acggccggag cgccttcccc cagaccttca ccactcagcg cccgctgcac
     5821 atcaacaagg cgggcagcag ccagggcgac actgagtcgc catcccacga gaagctggtg
     5881 gactccacct tcaccccgag cagctactcg tccaccggct ccaacgccaa catcaacaac
     5941 gccaacaaca ccgccctggg tcgcctccct cgccccgccg gctaccccag cacggtcagc
     6001 actgtggagg gccacgggcc ccccttgtcc cctgccatcc gggtgcagga ggtggcgtgg
     6061 aagctcagct ccaacaggtg ccactcccgg gagagccagg cagccatggc gggtcaggag
     6121 gagacgtctc aggatgagac ctatgaagtg aagatgaacc atgacacgga ggcctgcagt
     6181 gagcccagcc tgctctccac agagatgctc tcctaccagg atgacgaaaa tcggcaactg
     6241 acgctcccag aggaggacaa gagggacatc cggcaatctc cgaagagggg tttcctccgc
     6301 tctgcctcac taggtcgaag ggcctccttc cacctggaat gtctgaagcg acagaaggac
     6361 cgagggggag acatctctca gaagacagtc ctgcccttgc atctggttca tcatcaggca
     6421 ttggcagtgg caggcctgag ccccctcctc cagagaagcc attcccctgc ctcattccct
     6481 aggccttttg ccaccccacc agccacacct ggcagccgag gctggccccc acagcccgtc
     6541 cccaccctgc ggcttgaggg ggtcgagtcc agtgagaaac tcaacagcag cttcccatcc
     6601 atccactgcg gctcctgggc tgagaccacc cccggtggcg ggggcagcag cgccgcccgg
     6661 agagtccggc ccgtctccct catggtgccc agccaggctg gggccccagg gaggcagttc
     6721 cacggcagtg ccagcagcct ggtggaagcg gtcttgattt cagaaggact ggggcagttt
     6781 gctcaagatc ccaagttcat cgaggtcacc acccaggagc tggccgacgc ctgcgacatg
     6841 accatagagg agatggagag cgcggccgac aacatcctca gcgggggcgc cccacagagc
     6901 cccaatggcg ccctcttacc ctttgtgaac tgcagggacg cggggcagga ccgagccggg
     6961 ggcgaagagg acgcgggctg tgtgcgcgcg cggggtcgac cgagtgagga ggagctccag
     7021 gacagcaggg tctacgtcag cagcctgtag tgggcgctgc cagatgcggg ctttttttta
     7081 tttgtttcaa tgttcctaat gggttcgttt cagaagtgcc tcactgttct cgtgacctgg
     7141 agttaaccgg aacagcgtct tcattcattt ctgttgggac cagacgcgga gcctgggtgc
     7201 gcgagccgcc ctccgggagg aaggcgcccg gctgcgtctg cagaggcggg gagaggaggc
     7261 ggcgagggtc ccggggcgcg aggaaggcgc ctgccctctc ccagctcgca ggccccgggc
     7321 ccggccgcgc ctccgcgggg agagcacccc ggcttcccgc gcgccctcac caaaaggacc
     7381 ctacagcaaa cgggtgtctt tcgactctgc ttgtagaaac catttgcaca tattctgtac
     7441 gagcctcgct gtctccctag agccagggcc ctgcggattt ggagaaggga gcggggcagg
     7501 acttccagga ggaccccaac ccggcccgga gagggaggag gaggcctcca ggggcgcgga
     7561 gctctgggga tgggcgtcgg gccggcagtg gtgcggctca ctccgtccct gcccacctgc
     7621 gacgggatcc cccgaccggc acgggccacg ccgagctccc ggccagccgc cggcccgcag
     7681 gcagcgcgag ggaggagctg cgccgccggc tccgcccaac caggtggtgc tgagcttccg
     7741 ctgagcgctc ttttgttttg tggtttgaca cttttcttga cagcatgttg cagtttcttt
     7801 tcggttttgg ttttttttaa atgttttatt ttgctttccc agcgggaggg gaggaagaag
     7861 agtgtttaca aagtcctgta gccccctcac ctttctgttt tcacttttgc caatgtacat
     7921 cgggtttggt tttcttgtat tatttaaacg gttgtggttt cctttttcca cggaggttca
     7981 atagaagccg ctgcaggaga gttttaccaa ccattgtgta tgcccaataa tttgttatca
     8041 tttccttagg tagtaaccta tttttgttct ggtttggttc ggttatctaa tggaaaggta
     8101 actggcaatg cacttgatgt ggtcttgcac atgtgggtga tagagttggg ttccttttta
     8161 tgctgggtgt acaggtgggt ttgggagaga ggagcatgcg cgagagagtc tccgagtgtg
     8221 tgcgacgcgt gtgtgtgtgg tgggttgtct gtgtgcatat gtcctgcccg tgtatatgca
     8281 cccacaccat gtgcccgtgc acaccagtga ctacgcagtc ccccctttct ggtttagctg
     8341 tgggaagatc tgaatctggg gccgtttgaa agcaaaaaca aaccactgtc tctgcttctg
     8401 aaacgggaat cagtaactct ttgcattttc tgtcccacaa gatatgcaaa aacaatgcaa
     8461 taatattcat ttaaaaatac aattgtgagt tgtgttggca ttaaaactgt attttaaaaa
     8521 aagacagaaa tttaagggaa aaacacaaga aggcattttg cttcaatata ttccgtgtaa
     8581 tgttttattg cattgataat gtttctgttg aagaaaccgt tatacttgaa ttcaggtcag
     8641 tttcagtatt tttcaaatat ttttttaaaa ctgaattgca attgtgccaa gcgaatataa
     8701 tgaattgaat taagttggtt ttcggattca cttcttgtat attttgctgc atgtaaagta
     8761 aatcattttg tatttggagt gtgacaagct ttacctttga actcaagtgc ttttctatat
     8821 gtggttgggg gaaagggaac aagttttctt tagtttgcac aatgagcaaa ggtatcacca
     8881 gtgtagtcat tattctgctc tccacaaaca ggtttggaca ttactgtttt gcatatcttg
     8941 tgtttgctta catttccctc aatttttcca aaatcgtttg ctgggtatgt ttgtaccgcc
     9001 tcttgctgtg agagaccagg acctatttta ttccagtctt cactctgtcc actctgctct
     9061 ggtcatctga tttggtactt ctccaagaac agcccttcac tgtgaggtgc agggaggcgt
     9121 tctgatgagc cctcagtcac tgggccgtca tccgcatccc ccatggaaga ggtagctggc
     9181 tttcccttcc cttccaccac acggaatttt ctctttggct tccttaggaa agtgtacact
     9241 aaccgggagg ataaaattaa agtcaggctg cttggaggga ggggcatcct cacttccgga
     9301 ttcttgttgc tctacccaac aaggacagca ggggctcgag aaaggaactg gtgaaaccct
     9361 gatccatctg aaagtcaact ctgcgtgctc ctttctccat cccttcctca ctctggagca
     9421 gcctttcctt caggcttgcc ctaatgtttg ggctgccggg gagggggcca ggacaaggga
     9481 agaggcatcc ggagctcaca gtgggggtgg gaacagattt ttgtgggggc atctctaatg
     9541 ctcacttata tctccctaga acatcactct tttggtgctg tgtccttcaa atgtatgtca
     9601 acagtggtgg ctgaaaaggg actgctttgg ggaaaacagg acccaaccat tcacccagaa
     9661 ttgacccatt aaatctcttc cagtcctagt gttccctgag cccctcttgg cacatatata
     9721 agtaagctag aaattacaat aagggacagt ccattcctct atgacagctt gctggactga
     9781 ttcatgacaa agtggagaaa tgtactcaat actccccggt taacacagtc tagaaacaga
     9841 gtttctttat ggatatccac acccaagtca tccaaacttt cttgattcct tttcactgcc
     9901 atcaaggtcc tctagaaatt gagtttaggt atcatccttt gaaaagttcc caagatttct
     9961 accaggaggt acacacaggc gttccctgtc tagggcagga ggactatcct agcttgacct
    10021 tctgatccac tagaataaga ctggcgtatg atgcctgtca tcagaacaga ctggcacaag
    10081 tagtgacatc aatgaaccac agcacaatct tccaagtgat gtctactctc cacctaaaat
    10141 ggaattttcc ccatgacctt gtaaaacata attgtcacat cttccatacc cctcctgaca
    10201 gcccccaagt gtcaggagaa aacagtcagg ggctaagggc ccaagggact tgaagaaaca
    10261 acagtttaag gtctgcagtt tggtcaactt aattcttgtc ctccgaccag ccctgcctct
    10321 ttcatttcca gaccttggag aatttttccc agctttgatt cagaaggtac tagttataac
    10381 ccctttcctt cttcttaatc caataggcct cactctcact gggaaatcca ctcaaaggaa
    10441 caaggcaatg tctctcattc tatttcccag ttccaaattc caggtgcttg tctggagtga
    10501 agctacccgt tactttctcc cagcttttct ccacccagca tgtctcctgc ccatgcagct
    10561 gaagacagtg gggcaacctc aggagaagca gacctttcca tgcccaagtt catctcctga
    10621 gcaacagtga cacctagaaa atgaggactt tggaagtcac ccaaaagatg gtggctactt
    10681 tatggagtcc tgaagataca cagccaccac tcctaaaggc aaagaaagaa aacacgaatg
    10741 taggtcaggg atagagtgga accctggtca tcggggtttt tagcctcatc gtgggaaagg
    10801 tggtaaagga ggatgatggc atctccatcc ctagaggcca agaattgaaa tatcattgtc
    10861 aaggattaga aacaattcag caaagaggcc acaaaaaggg cctgctgact cccagaagac
    10921 ctctttaaac cccaggggag gcaaatactt gctgatggag tctgggccgt ttccatattt
    10981 taaagaagac ctgcctctgg ggcaaatgtc agcacagaga ggactgggag gagaatggag
    11041 gcaagaaaag ggcatatttt gactccctct gtgcctcttc ccagttcatg gaaggatgtg
    11101 ttcagcttac ccacccacag tgaccagtgt ggtggagccg ctgacatctc aaggatctat
    11161 ttgggaaggt gagaagagta ctcattccat ctgggggtgt tgttccagcc acatcagcct
    11221 acctggtggg atgtgggggt gtctgccacc ctgtcccccc tctgctgatg tccctcccct
    11281 caggctgtcc aggtgccacc tgacacaggc tgctgtgcaa agacaggcgg ggaagcccaa
    11341 acctcactcc cagggaggcc ctcagccgcc agagtccagg ttctccagag gctacgattt
    11401 gaggaggttg agggggaaga caggagggaa agaaaagtcc tacaactgtc aggaatgggg
    11461 cacctttccc tgtccctaag caaagctccc tcttcccact gccctcccca gccccagctc
    11521 cctgtcctcc ccaacaccta gtgagaaaga cggtgcgtgg aagggagtcc catgggcaga
    11581 tgcttacacg acctctttgt gaagcctctt ctgggtttaa cttcattcat caatttattc
    11641 ttatgtcaaa gcaatgaaac ttttctttct ggagccagat accaatacaa caggtgaacg
    11701 ggtttctgcc acatctctac attgacgggg gatgcttgaa caacccccct cactacacag
    11761 acacacaccg ttaaggcaca agggctgggg ttgagctcta gatgagggac tttcctgctc
    11821 ctgcaagggt gagcactgta tacacagaca aggagggtgc agtagagtga ctcccttgga
    11881 tggaagtagt accatcagaa cctactatta ttatgacata aattctattt acatacattg
    11941 agagaatact acaatcaaca ctttttcctg ggatgacttt aagaggtttg agccacagca
    12001 cctgaagtgg caaagatcca tggtctttgt agggtattag agaactcttc cagtcacctc
    12061 tgaaagcact ctagatcttg cagctgagtg gatgaagtgt aacaaatctg ttgcacgctg
    12121 agaggagtca gaattagcat ttttcatgaa agttccccac gtctctacta agaatgagga
    12181 agaaaagact aagactaggt aattacacag aggcttgaaa tgttacatca ccagagccaa
    12241 gtcctctccc ttcagatcag ttactggctg ctacacaggg acacccccac cttttcaggg
    12301 catcccatgc actccacttc tcaggatcta aggaatttga ctttgtaggg atcccagaaa
    12361 gggcactgtg ccacttcccc tggtgtgaat cagacataca ttgtacattc atttctaaaa
    12421 ttcactcatg cacctcaaac caaggtcatt atccaaaaaa aaaaaaaaaa agctctgggt
    12481 ggaagagttt gtaagtttta agagagggtc atttctatgt gaggaaatgc agaaatggac
    12541 agaatgattc ttattcactg tttgggtctg gagaattccc attgtggaaa tcttagagat
    12601 ctcaagttta ttaccaaggg aataaggaaa aaaaggtgag caggcaccag gccaagcagt
    12661 ggctcccttg ccaaggaacc tgaggctgca ggtttcaggg acccccttga agaaacctct
    12721 cctggccatt ggccaggaga aaagagaagt ctctcctgta gagtcacaag agaagcaaaa
    12781 gagggtgggt cactgggtcc tggacatagc ccccaacccc aagacttccc aatatggaga
    12841 aactacacca atgtttaaaa ggggaaaagg aaagaacttg tacatcaagg gaagatgatt
    12901 tgtaaacaca cagtcctgtg cagaaagatc cccttcagga ggtgtctcca gcatcccaaa
    12961 gctgtgcgca ccttctcttt tcctgcctca ggccacctat gcatccagct gcagcccata
    13021 cccacacctg aaatccatct cttgaatccc agccaggtta tataccaccc cattgccatg
    13081 tcctgtcctg gccagaatgc atgctgttcc cccaagcctc gtgggagtga ggccatggga
    13141 aacagagatg agcatgtctg gacaagtctg tgatggtagt ggatgagaat aacccatggc
    13201 aaaacacgca cattcattaa gaaatagggc gacagattcc ccgttggtga agcactgaaa
    13261 ggtctattac tctcataata ttgctgtttt attttaatcc accagagcta ccatgcaaaa
    13321 ctttcctcct gtgaaacgct ccagataaag ctcctctaat ctccccttcc ctcatgtcct
    13381 ccagctcaaa cccaccttca tcccccaaac caatctgtat catgcctgtt atcagagagg
    13441 cacagaaaga tgggcagtgc ctccgttgtc accattcccc acacccctac acacccccac
    13501 accctcccct ccaggctcca cgacttcaca gtcttactgt tgtaaatatc attgtacagt
    13561 ttgtaatcct caaataatcc cattgtcaga ggcctcgcct gatgggcctt ctcaccctcg
    13621 agaaaggcca gggaatctag aaggggcaac ccttcaagga gagcttcagg gtcatctctg
    13681 tgtgagacac tattgtatat tcctgtaaga ttgcattttt atctaaggaa tgatgttatt
    13741 taaaaaacaa acaaaaaaca caaaaaataa gaattgcaaa taaatttctt aacaatgtct
    13801 a
//
