LOCUS       NM_001012993            2687 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens chromosome 9 open reading frame 152 (C9orf152), mRNA.
ACCESSION   NM_001012993 XM_376899
VERSION     NM_001012993.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2687)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2687)
  AUTHORS   Liu,L., Fan,Y., Zhang,Z., Yang,C., Geng,T., Gong,D., Hou,Z. and
            Ning,Z.
  TITLE     Analysis of gene expression and regulation implicates C2H9orf152
            has an important role in calcium metabolism and chicken
            reproduction
  JOURNAL   Anim Reprod Sci 176, 1-10 (2017)
   PUBMED   27889102
REFERENCE   3  (bases 1 to 2687)
  AUTHORS   Ozyildirim,A.M., Wistow,G.J., Gao,J., Wang,J., Dickinson,D.P.,
            Frierson,H.F. Jr. and Laurie,G.W.
  TITLE     The lacrimal gland transcriptome is an unusually rich source of
            rare and poorly characterized gene transcripts
  JOURNAL   Invest Ophthalmol Vis Sci 46 (5), 1572-1580 (2005)
   PUBMED   15851553
REFERENCE   4  (bases 1 to 2687)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL353598.12.
            
            On Jun 8, 2020 this sequence version replaced NM_001012993.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC110807.1, BX648620.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000400613.5/ ENSP00000383456.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-773               AL353598.12        46168-46940         c
            774-2687            AL353598.12        38342-40255         c
FEATURES             Location/Qualifiers
     source          1..2687
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q31.3"
     gene            1..2687
                     /gene="C9orf152"
                     /gene_synonym="bA470J20.2"
                     /note="chromosome 9 open reading frame 152"
                     /db_xref="GeneID:401546"
                     /db_xref="HGNC:HGNC:31455"
     exon            1..773
                     /gene="C9orf152"
                     /gene_synonym="bA470J20.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             581..1300
                     /gene="C9orf152"
                     /gene_synonym="bA470J20.2"
                     /codon_start=1
                     /product="uncharacterized protein C9orf152"
                     /protein_id="NP_001013011.2"
                     /db_xref="CCDS:CCDS35102.2"
                     /db_xref="GeneID:401546"
                     /db_xref="HGNC:HGNC:31455"
                     /translation="MEGLPCPCPALPHFWQLRSHLMAEGSRTQAPGKGPPLSIQFLRA
                     QYEGLKRQQRTQAHLLVLPKGGNTPAPAESMVNAVWINKERRSSLSLEEADSEVEGRL
                     EEAAQGCLQAPKSPWHTHLEMHCLVQTSPQDTSHQVHHRGKLVGSDQRLPPEGDTHLF
                     ETNQMTQQGTGIPEAAQLPCQVGNTQTKAVESGLKFSTQCPLSIKNPHRSGKPAYYPF
                     PQRKTPRISQAARNLGLYGSA"
     exon            774..2687
                     /gene="C9orf152"
                     /gene_synonym="bA470J20.2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2660..2665
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C9orf152"
                     /gene_synonym="bA470J20.2"
                     /note="hexamer: AATAAA"
     polyA_site      2687
                     /gene="C9orf152"
                     /gene_synonym="bA470J20.2"
                     /note="major polyA site"
ORIGIN      
        1 agtcccagct ctgccaggaa aggggagact tcaccgtggc actgggaatt ggattctaaa
       61 ctttaggatc aagcaatgga aggacctgga ataagacacc ttcttgaccc ccctgaaggg
      121 ctctgagcag ctgggcttgc ctttctcttt gctcccccag tcctcccctt acttctcggt
      181 ctcccactcc ccatcactcc tttccctgcc tcctcctgcc tgtctccatc ttcctccctc
      241 tctttcttct ctcgccccat taatccccgc ttgtcactat cacctccttc ctccagtctt
      301 tcccccttcg ctgccccttc tttcctctga catttccttc tcctcttact gccactgtct
      361 cccacctttc tcctccccca catttctccc tatccctacc tcctcttccc cttcatcttt
      421 ctccttcccc cttatttttc tatctccttc ctcagtccca ctcctctttc caccctcctt
      481 ttgcccgtca cttctccttc tccctcactg ccccctccct ctctctcccc tccccaggtc
      541 ctgccccacc cagctgtgtt tgcttttctc ccggatccgg atggaggggt tgccctgccc
      601 gtgcccagcc ctgccccact tctggcagct taggtctcac ttaatggctg agggctccag
      661 gactcaggcc cctgggaaag ggcccccact cagcatccag ttcctgcgag cccagtatga
      721 aggcttgaag aggcagcaga ggacccaggc ccacctcctg gtgcttccaa aaggaggaaa
      781 cacacctgct cctgcagaat cgatggtcaa tgctgtttgg attaacaagg agagaagaag
      841 ctcactgtcc ctggaagagg cagattctga ggtggagggg aggctggagg aggctgccca
      901 gggctgcctt caggccccca agtctccatg gcacacgcac ctggagatgc attgtttggt
      961 ccaaacctcc ccccaggaca ccagtcatca agtacatcat aggggcaagc ttgtgggatc
     1021 tgatcaaagg ctccctcctg aaggagacac acacttgttt gaaaccaatc agatgactca
     1081 gcaaggaacc ggaatcccag aggctgccca gcttccatgc caggtgggca atacccaaac
     1141 aaaggcagtg gaatctggct taaaattcag cactcaatgt cctctttcca taaagaaccc
     1201 acacaggtct ggcaaaccag cttactatcc atttccccag aggaaaacac ccaggatctc
     1261 ccaagctgcc cggaacctgg gcttatatgg ctcagcgtga agctttctat tctgccagat
     1321 gtcttgacct tgaggccacc tatggcctta tagaagaacc aaggaggcag agccacaacg
     1381 aggtctctag ctatgagcaa gaactggact aacctaatta taggaattgt gggagacgaa
     1441 cttcacaatg gtaacatggt tttacccttc caataagaag agacttccca ggccaaattg
     1501 cccacagttt aggatgaaga ggactgtctg gtcagtgcag ccccattctg acattactat
     1561 gaggtcctgg atatccattc cttggggagg accagtaaga catctgctcc atccctggaa
     1621 ctggataatt ttggaacata aaccagggac ctagccaaca gaatgcctta gcaatgccca
     1681 ggggtcaatg ggcgtggcat tcttgttttc aatgtcttct gatgatttct catatattct
     1741 ggagaagaca agctctgaga attcagatgc tttttctggt ggctatgtct ggggggccat
     1801 ctcacttaga agtcacaaca ctcattggca gtgatcacat catttcaatt tgggcttccc
     1861 aaagtatggt cacccagggt atgaaggtga gatcaatgct acctaccatt ttgtgtcttt
     1921 aaggggtctt tagaaagggc taatcatctg tcactgctca ctgagacatg tacattccag
     1981 catcatcaca gagttatctc cttccttcct tccttccttc cttccttcct tccttctgtc
     2041 tctccctccc tccctccctt cctcccttct ttccttcttt ctttcctctc ttccttcttg
     2101 ccttctttcc tgccttcctg cctatctttt ctctctctct ctctctgcaa attaagttct
     2161 tattaaaaac tgccaatcat tgacgatata taatgatgag atcctgaaca aaagaggcaa
     2221 agaaatgctc ctacttgaaa aatacacatt ccctatagac tgcctcctgt ttagtccaac
     2281 ttagatcact cagatccttc ctgggatcaa atatattttt aaacctaaga caaagcgaag
     2341 caggtgtcac ttgggtgata gggaaaaaag cttgtatttc ctggttaatg tttagctttt
     2401 gtaatgctat ttaaacacac ctaaggtgcc tttccctcat ctcaggtgct ttctctgtaa
     2461 agtttcactc ccacctttct tttctctgca tggccgtcca gtcttgccca tctacatcca
     2521 gagctgttaa ctagtagtgt cattacctgt gaaaaacatg tagaagcttc cttgaaccac
     2581 ccagaaatcc actcaaattt ggggattgtc attccttttg tgaataatta atacaattca
     2641 gttgtttttt aaatattcta ataaaaaagg aaattttctc aaaaaaa
//
