LOCUS       NM_001386514            1221 bp    mRNA    linear   PRI 05-AUG-2024
DEFINITION  Homo sapiens chromosome 7 open reading frame 78 (C7orf78),
            transcript variant 6, mRNA.
ACCESSION   NM_001386514
VERSION     NM_001386514.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1221)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   2  (bases 1 to 1221)
  AUTHORS   Brandenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J.,
            Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Mandalam,R.,
            Lebkowski,J. and Stanton,L.W.
  TITLE     Transcriptome characterization elucidates signaling networks that
            control human ES cell growth and differentiation
  JOURNAL   Nat Biotechnol 22 (6), 707-716 (2004)
   PUBMED   15146197
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC013470.10, AC092064.4 and AC005281.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2144333,
                              SAMN03267765 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000636804.2/ ENSP00000490444.1
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               AC013470.10        18648-18753         c
            107-562             AC092064.4         1778-2233
            563-647             AC092064.4         4627-4711
            648-790             AC092064.4         7709-7851
            791-870             AC092064.4         9820-9899
            871-1221            AC005281.2         5063-5413
FEATURES             Location/Qualifiers
     source          1..1221
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p21.3"
     gene            1..1221
                     /gene="C7orf78"
                     /note="chromosome 7 open reading frame 78"
                     /db_xref="GeneID:102725191"
                     /db_xref="HGNC:HGNC:55185"
     exon            1..106
                     /gene="C7orf78"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..874
                     /gene="C7orf78"
                     /note="isoform 3 is encoded by transcript variant 6"
                     /codon_start=1
                     /product="putative uncharacterized protein C7orf78 isoform
                     3"
                     /protein_id="NP_001373443.1"
                     /db_xref="CCDS:CCDS94055.1"
                     /db_xref="GeneID:102725191"
                     /db_xref="HGNC:HGNC:55185"
                     /translation="MIPPCENAPHIIYHESQRGTRDRDIAKRLQYPSRQDLNSKWKKS
                     VLQPPQCKMKVNVWEIKPPDFSYKLYTSLRIPERSSKPIKEEKRRKKISFPETMLHLP
                     SIRNHPKEVTAPKFITTFPHLDLQKAKLMFVKSGQYPRGVYVNPKPHDFRQYQPGLPN
                     FETTYEKDPFGLKFKSQHLSTVHGYQLPKDDKQKTSTERFITHKHCECTWDSKLILTK
                     APWPVRSASYTRHRRQRDAYSAFMDRVEEKFTKICKSR"
     exon            107..562
                     /gene="C7orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            563..647
                     /gene="C7orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            648..790
                     /gene="C7orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            791..870
                     /gene="C7orf78"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1221
                     /gene="C7orf78"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaaagcaaa ggataatgtt aaactgttag tctctcttgg ctttacagaa aagatttgct
       61 gagatatatt actctaaaac ttttatgaaa agctatcttt caaatgattc ctccatgtga
      121 aaatgccccc cacataatat accatgagtc tcagagaggc acaagagata gggatattgc
      181 aaagaggctg caatatcctt cacgacagga tctcaactcc aaatggaaaa aaagtgttct
      241 gcaacctcca caatgtaaaa tgaaagttaa tgtatgggaa ataaagcctc ctgattttag
      301 ctacaaactg tatacatctt tgagaattcc agaaagatca tcaaaaccaa ttaaggaaga
      361 aaaaaggagg aaaaaaatca gttttccaga aacaatgctt cacttgccca gcataaggaa
      421 tcatcctaag gaggttacag ctcctaaatt tataactaca tttccacatc tggatttaca
      481 aaaagcaaag ttaatgtttg tgaagagtgg acaatatcca aggggtgtat atgtcaatcc
      541 caaaccacat gactttcgac agtaccaacc tggtttacca aactttgaga caacttatga
      601 aaaggacccc tttggattaa aatttaaatc acaacactta agtacagtac atgggtacca
      661 gttaccgaaa gatgataaac agaagactag tacagaaaga tttatcaccc acaagcattg
      721 tgaatgcacc tgggattcaa aactaatttt gacgaaagcc ccatggcctg ttagatctgc
      781 ttcatataca agacatagaa ggcagcgtga tgcatacagt gcatttatgg atcgtgtgga
      841 agaaaagttt acaaagatat gcaagagcag atagctgatg gaccaaaaca gcatagggct
      901 tcctgaactc tggcctgaat gttcatctcc cgtgcatttc ccagtgagaa cattgatgaa
      961 ttctggcacc ttcctggatt ctacagaaat ctgcactctc ccagaggcat gagaaagtgc
     1021 taaaacaaca aatgaaagtt gcataatttg aaattccctt gttaccacag ggatcagaat
     1081 ccaatcataa ggcttttgat ttagtttgtg aaagttagat cttgcaacta tgagtggaaa
     1141 tgctgataat gtgctttctg ttaatgtcca aagttaaaga tgctctagtc tcaggtaaag
     1201 ctaatgtgag acaaacaaca a
//
