LOCUS       NM_145304               1153 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens chromosome 7 open reading frame 33 (C7orf33), mRNA.
ACCESSION   NM_145304
VERSION     NM_145304.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1153)
  AUTHORS   Scherer,S.W., Cheung,J., MacDonald,J.R., Osborne,L.R.,
            Nakabayashi,K., Herbrick,J.A., Carson,A.R., Parker-Katiraee,L.,
            Skaug,J., Khaja,R., Zhang,J., Hudek,A.K., Li,M., Haddad,M.,
            Duggan,G.E., Fernandez,B.A., Kanematsu,E., Gentles,S.,
            Christopoulos,C.C., Choufani,S., Kwasnicka,D., Zheng,X.H., Lai,Z.,
            Nusskern,D., Zhang,Q., Gu,Z., Lu,F., Zeesman,S., Nowaczyk,M.J.,
            Teshima,I., Chitayat,D., Shuman,C., Weksberg,R., Zackai,E.H.,
            Grebe,T.A., Cox,S.R., Kirkpatrick,S.J., Rahman,N., Friedman,J.M.,
            Heng,H.H., Pelicci,P.G., Lo-Coco,F., Belloni,E., Shaffer,L.G.,
            Pober,B., Morton,C.C., Gusella,J.F., Bruns,G.A., Korf,B.R.,
            Quade,B.J., Ligon,A.H., Ferguson,H., Higgins,A.W., Leach,N.T.,
            Herrick,S.R., Lemyre,E., Farra,C.G., Kim,H.G., Summers,A.M.,
            Gripp,K.W., Roberts,W., Szatmari,P., Winsor,E.J., Grzeschik,K.H.,
            Teebi,A., Minassian,B.A., Kere,J., Armengol,L., Pujana,M.A.,
            Estivill,X., Wilson,M.D., Koop,B.F., Tosi,S., Moore,G.E.,
            Boright,A.P., Zlotorynski,E., Kerem,B., Kroisel,P.M., Petek,E.,
            Oscier,D.G., Mould,S.J., Dohner,H., Dohner,K., Rommens,J.M.,
            Vincent,J.B., Venter,J.C., Li,P.W., Mural,R.J., Adams,M.D. and
            Tsui,L.C.
  TITLE     Human chromosome 7: DNA sequence and biology
  JOURNAL   Science 300 (5620), 767-772 (2003)
   PUBMED   12690205
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC021251.2 and AC005229.2.
            
            On Nov 22, 2018 this sequence version replaced NM_145304.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC021251.2, CV029100.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000307003.3/ ENSP00000304071.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-720               BC021251.2         202-921
            721-721             AC005229.2         145860-145860       c
            722-1153            BC021251.2         923-1354
FEATURES             Location/Qualifiers
     source          1..1153
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q36.1"
     gene            1..1153
                     /gene="C7orf33"
                     /note="chromosome 7 open reading frame 33"
                     /db_xref="GeneID:202865"
                     /db_xref="HGNC:HGNC:21724"
     exon            1..364
                     /gene="C7orf33"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..694
                     /gene="C7orf33"
                     /codon_start=1
                     /product="uncharacterized protein C7orf33"
                     /protein_id="NP_660347.1"
                     /db_xref="CCDS:CCDS5890.1"
                     /db_xref="GeneID:202865"
                     /db_xref="HGNC:HGNC:21724"
                     /translation="MQVEVQSLSLEECPWRLPGPQCECEALLPSGARRRIDLRLSGRA
                     VAVWVHVRGGPGQFNLSYATGRHKKPNPHQNMNRGMEFIAPVSAPTKSGAPWHFLSQG
                     PTDAQRAVRIRPGTRMGLSSDPVVGTLSSSYLDLLTLSYKPGRTVTSSYLNVRGHEVR
                     KLQNSVEATRISRTDSS"
     exon            365..619
                     /gene="C7orf33"
                     /inference="alignment:Splign:2.1.0"
     exon            620..1153
                     /gene="C7orf33"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1131..1136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C7orf33"
                     /note="hexamer: AGTAAA"
     polyA_site      1153
                     /gene="C7orf33"
                     /note="major polyA site"
ORIGIN      
        1 acttatggtg atgccaatcc agtggtcagg agcgaggcgc ccagcctgtg tctgaatcct
       61 cctactgacc ctggggatcc gtgcgacttg atcttagata ttggtggtga agcgccgctc
      121 tccttgacag catccaggaa aggtaattac ctttgccaaa atgcaagtgg aagttcaaag
      181 cctcagcctt gaagagtgtc cctggagact tccaggcccc caatgtgaat gtgaagccct
      241 cctgcccagt ggggcaaggc gccggattga ccttcgcctg agtgggaggg cagtcgctgt
      301 ttgggtccac gttaggggcg gtccaggtca atttaacttg tcatatgcca cgggaagaca
      361 taagaagcca aacccacacc aaaacatgaa ccgggggatg gaatttattg ctcctgtatc
      421 agctcccacc aaatctggtg ccccgtggca ttttctttct caaggtccca cggatgccca
      481 gagagcagtc agaatcaggc caggcaccag gatgggcttg tcctcagatc cagttgtcgg
      541 caccttgtct tccagttacc tagatctgct aactctctct tacaagcctg ggaggacagt
      601 gacaagttca tacctaaacg tacgtgggca tgaagtaaga aagctccaga attctgttga
      661 ggccacaagg atttccagaa ctgacagcag ttaagaattt tgcagaatct aagagtcaca
      721 tctctaaatt tgtgtagatt gtgaaatctc ttcttgcaag aaaaaagaga aatagctgaa
      781 gttctggaaa taacagttga tgaaaacttg gtaatctgaa gtctgaactt tgaacaccag
      841 cagacaggct gagaattctc tttgatcatg agcccaagtt ccacgtgtac ctgcaggaat
      901 ctgtgtggca tttgtgcact ggtgtggggc ccaggagagg accacggagt gacaagccac
      961 caggttctaa agggagacga agatccccag aggacctgga tagagatgtt tccctgacca
     1021 ttgtctgctg tgtgctcccg atgatgagac tctagagttt acaactgaaa cacactgtca
     1081 tttatgatat tatttgtaat atctggtatg tctaagtaaa acatgcattc agtaaaactc
     1141 gcgatgaaac tta
//
