LOCUS       NM_001145020             627 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens chromosome 6 open reading frame 52 (C6orf52),
            transcript variant 1, mRNA.
ACCESSION   NM_001145020 XM_001718541 XM_371798 XM_938497
VERSION     NM_001145020.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 627)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL358777.12, BC016820.1, AI376550.1, AI809192.1 and AW293245.1.
            
            On Aug 13, 2020 this sequence version replaced NM_001145020.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14243140.7347394.1,
                                           ERR4352442.158199.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000259983.8/ ENSP00000259983.3
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AL358777.12        118054-118063       c
            11-83               BC016820.1         5-77
            84-144              AI376550.1         287-347             c
            145-590             AI809192.1         40-485              c
            591-627             AW293245.1         20-56               c
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p24.2"
     gene            1..627
                     /gene="C6orf52"
                     /note="chromosome 6 open reading frame 52"
                     /db_xref="GeneID:347744"
                     /db_xref="HGNC:HGNC:20881"
     exon            1..123
                     /gene="C6orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            124..205
                     /gene="C6orf52"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..593
                     /gene="C6orf52"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="putative uncharacterized protein C6orf52 isoform
                     1"
                     /protein_id="NP_001138492.1"
                     /db_xref="CCDS:CCDS47371.1"
                     /db_xref="GeneID:347744"
                     /db_xref="HGNC:HGNC:20881"
                     /translation="MAQPESSADFGIAQQNNYYCYWQSLPSAIRVKQEFQPSQSYRYG
                     NWYARQHGSYLLSGYSYGCAVDGNGKDCFSAHETPEHTAGTLVMPKETTPLAENQDED
                     PLEDPHLHLNIEESNQEFMVKSEELYDSLMNCHWQPLDTVHSEIPDETPK"
     exon            206..404
                     /gene="C6orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            405..450
                     /gene="C6orf52"
                     /inference="alignment:Splign:2.1.0"
     exon            451..627
                     /gene="C6orf52"
                     /inference="alignment:Splign:2.1.0"
     regulatory      606..611
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C6orf52"
                     /note="hexamer: ATTAAA"
     polyA_site      627
                     /gene="C6orf52"
                     /note="major polyA site"
ORIGIN      
        1 gacttccggc cggttgctta ggggctgtag cgccggcagc gtgcattgtt gtgggctgtg
       61 tactagtagg gtaggagttt ttgttcaggg accagcggaa cgaggctttc tgtcgttaat
      121 aggtttctgg gtaaatggcc caaccagaga gttctgcaga ttttggcata gctcaacaaa
      181 ataactatta ctgctactgg caaagtctcc cctctgctat tagagtgaag caggagttcc
      241 agcccagcca gagttaccgc tatggcaact ggtatgcgcg acagcacggc tcttaccttc
      301 tttctggcta cagctatggc tgtgcagtgg atggaaatgg aaaggactgt ttttctgcgc
      361 atgagacccc tgaacacaca gctggaactc tggttatgcc taaggaaacc acacctctag
      421 ctgaaaacca agatgaagac ccactagaag atccacatct tcatttgaat attgaggaat
      481 caaaccaaga gtttatggtg aaaagtgaag aactctacga ctccctcatg aattgccact
      541 ggcagcctct ggacacagtt cactccgaaa tcccagatga gaccccgaag tgaagcaagg
      601 tgttcattaa actccgcaat tatcata
//
